References of "2000"
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See detailFonctionnement exécutif et maladie d’Alzheimer
Collette, Fabienne ULg

Scientific conference (2000, November)

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See detailLes fibroses pulmonaires idiopathiques: nouvelle classification histopathologique et aspects cliniques
Blaise, Pierre ULg; Louis, Renaud ULg; Bartsch, Pierre ULg

in Revue Médicale de Liège (2000), 55(11), 986-90

Idiopathic pulmonary fibrosis (IPF) comprises different interstitial lung diseases of unknown origin. They are classified into four groups based on pathologic criteria: UIP, DIP, AIP and NSIP. This ... [more ▼]

Idiopathic pulmonary fibrosis (IPF) comprises different interstitial lung diseases of unknown origin. They are classified into four groups based on pathologic criteria: UIP, DIP, AIP and NSIP. This classification helps in terms of prognosis and treatment. In addition to history, physical examination and common investigations (chest X ray, pulmonary function testing), a bronchoalveolar lavage (BAL), a high-resolution CT scan and ideally a open-lung biopsy are needed to establish a precise diagnosis. The patients are usually treated by immunosuppressive agents, and mainly by corticoids. However, in UIP, lung transplantation is the only way to improve survival. [less ▲]

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See detailIdentification des compétences recherchées pour l’animation en piscine
Cloes, Marc ULg

Scientific conference (2000, November)

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See detailCultures visuelles au XIXe siècle
Havelange, Carl ULg

Book published by Ligue Braille (2000)

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See detailWalter Demaria, architetture 1967 - 2000
Cohen, Maurizio ULg

Book published by Skira (2000)

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See detailModelling gas flow through the faulted clayey overburden of a deep water offshore reservoir.
Radu, Jean-Pol ULg; Charlier, Robert ULg; Cui, Y.-J. et al

in 3rd Euroconference on rock physics and rock mechanics (2000, November)

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See detailLe point sur le time-sharing
Vanbrabant, Bernard ULg

in Droit des biens (2000)

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See detailStrep B OIA and prenatal cultures for identification of GBS carriers at delivery
Melin, Pierrette ULg

Conference (2000, October 31)

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See detailDetermination of the Enantiomers of 3-Tert.-Butylamino-1,2-Propanediol by High-Performance Liquid Chromatography Using Mass Spectrometric Detection
Toussaint, B.; Streel, B.; Ceccato, Attilio ULg et al

in Journal of Chromatography. A (2000), 896(1-2), 201-7

The chiral synthesis of beta-blockers such as (S)-timolol requires a sensitive analytical method for the enantioseparation of its intermediate, 3-tert.-butylamino-1,2-propanediol, in the ng/ml range. The ... [more ▼]

The chiral synthesis of beta-blockers such as (S)-timolol requires a sensitive analytical method for the enantioseparation of its intermediate, 3-tert.-butylamino-1,2-propanediol, in the ng/ml range. The method developed is based on on-line normal-phase LC-MS-MS using a chiral stationary phase and an atmospheric pressure chemical ionization (APCI) interface. The MS detection of 3-tert.-butylamino-1,2-propanediol was first optimized with a pneumatically-assisted electrospray interface (ionspray). The APCI interface was then selected for LC-MS-MS because of the incompatibility of electrospray with n-hexane. The method was validated for both enantiomers in the 25-500 ng/ml concentration range. [less ▲]

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See detailQuantitative Analysis of N-Acetylcysteine and Its Pharmacopeial Impurities in a Pharmaceutical Formulation by Liquid Chromatography-Uv Detection-Mass Spectrometry
Toussaint, B.; Pitti, C.; Streel, B. et al

in Journal of Chromatography. A (2000), 896(1-2), 191-9

A new method for the simultaneous determination of N-acetylcysteine and its pharmacopeial impurities, cysteine, cystine, N,N'-diacetylcystine and N,S-diacetylcysteine in an effervescent tablet has been ... [more ▼]

A new method for the simultaneous determination of N-acetylcysteine and its pharmacopeial impurities, cysteine, cystine, N,N'-diacetylcystine and N,S-diacetylcysteine in an effervescent tablet has been developed. The method is based on on-line LC-UV-MS using a pneumatically-assisted electrospray interface (ionspray). The stability of the thiol moieties of the analytes was ensured by the acidic pH of the LC mobile phase. Quantitation of N-acetylcysteine was performed with UV detection to avoid ion-source overloading effect due to its higher concentration, whereas the impurities could be easily separated and quantified in MS. The method was validated in terms of stability, linearity, precision and accuracy. [less ▲]

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See detailLa détection des signaux financiers annonciateurs de faillite en contexte PME : une approche méthodologique spécifique
Van Caillie, Didier ULg

in AIREPME (Ed.) Actes du 5ème Congrès International Francophone sur la PME (2000, October 26)

This paper proposes and discusses a structured and coherent methodology allowing to build up early warning business failure prediction models that are really able to incorporate the specificites of the ... [more ▼]

This paper proposes and discusses a structured and coherent methodology allowing to build up early warning business failure prediction models that are really able to incorporate the specificites of the financial data published by SMEs. [less ▲]

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See detailThe Extreme-Right in Western Europe : a Reevaluation
Martiniello, Marco ULg

Scientific conference (2000, October 25)

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See detailSyndromes paranéoplasiques du système nerveux périphérique
DIVE, Dominique ULg; WANG, François-Charles ULg

Scientific conference (2000, October 24)

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See detailQuelques compositeurs belges à la Monnaie : le projet discographique du tricentenaire
Pirenne, Christophe ULg

Conference given outside the academic context (2000)

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See detailL’empreinte de Brecht en Belgique
Delhalle, Nancy ULg

Conference (2000, October 20)

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See detailGene activation by varicella-zoster virus IE4 protein requires its dimerization and involves both the arginine-rich sequence, the central part, and the carboxyl-terminal cysteine-rich region
Baudoux, Laurence; Defechereux, Patricia; Rentier, Bernard ULg et al

in Journal of Biological Chemistry (2000), 275(42), 32822-32831

Varicella-zoster virus (VZV) open reading frame 4-encoded protein (IE4) possesses transactivating properties for VZV genes as well as for those of heterologous viruses. Since most transcription factors ... [more ▼]

Varicella-zoster virus (VZV) open reading frame 4-encoded protein (IE4) possesses transactivating properties for VZV genes as well as for those of heterologous viruses. Since most transcription factors act as dimers, IE4 dimerization was studied using the mammalian two-hybrid system. Introduction of mutations in the IE4 open reading frame demonstrated that both the central region and the carboxyl-terminal cysteine-rich domain were important for efficient dimerization. Within the carboxyl-terminal domain, substitution of amino acids encompassing residues 443-447 totally abolished dimerization. Gene activation by IE4 was studied by transient transfection with an IE4 expression plasmid and a reporter gene under the control of either the human immunodeficiency virus, type 1, long terminal repeat or the VZV thymidine kinase promoter. Regions of IE4 important for dimerization were also shown to be crucial for transactivation. In addition, the arginine-rich domains Rb and Re of the amino-terminal region were also demonstrated to be important for transactivation, whereas the Ra domain as well as an acidic and bZIP-containing regions were shown to be dispensable for gene transactivation. A nucleocytoplasmic shuttling of IE4 has also been characterized, involving a nuclear localization signal identified within the Rb domain and a nuclear export mechanism partially depending on Crm-1. [less ▲]

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