![]() Nuclear Factor-Kappa B, Cancer, and ApoptosisBours, Vincent ; ; et alin Biochemical Pharmacology (2000), 60(8), 1085-9 The role of nuclear factor (NF)-kappa B in the regulation of apoptosis in normal and cancer cells has been extensively studied in recent years. Constitutive NF-kappa B activity in B lymphocytes as well as ... [more ▼] The role of nuclear factor (NF)-kappa B in the regulation of apoptosis in normal and cancer cells has been extensively studied in recent years. Constitutive NF-kappa B activity in B lymphocytes as well as in Hodgkin's disease and breast cancer cells protects these cells against apoptosis. It has also been reported that NF-kappa B activation by tumor necrosis factor (TNF)-alpha, chemotherapeutic drugs, or ionizing radiations can protect several cell types against apoptosis, suggesting that NF-kappa B could participate in resistance to cancer treatment. These observations were explained by the regulation of antiapoptotic gene expression by NF-kappa B. However, in our experience, inhibition of NF-kappa B activity in several cancer cell lines has a very variable effect on cell mortality, depending on the cell type, the stimulus, and the level of NF-kappa B inhibition. Moreover, in some experimental systems, NF-kappa B activation is required for the onset of apoptosis. Therefore, it is likely that the NF-kappa B antiapoptotic role in response to chemotherapy is cell type- and signal-dependent and that the level of NF-kappa B inhibition is important. These issues will have to be carefully investigated before considering NF-kappa B as a target for genetic or pharmacological anticancer therapies. [less ▲] Detailed reference viewed: 15 (6 ULg) Local buckling in case of fireFranssen, Jean-Marc ; Conference (2000, October 13) Detailed reference viewed: 11 (0 ULg) Etude de la structure physique du territoire dans le périmètre d'extension et les pôles d'activités économiques de l'aéroport de Bierset et dans les franges d'urbanisation des zones d'habitat: FActuers géotchniques et hydrogéologiques (Avant-projet de révision ponctuelle des plans de secteur de Liège et de Huy-Waremme)Ruthy, Ingrid ; ; Monjoie, Albéric ![]() Report (2000) Detailed reference viewed: 19 (0 ULg) Prévention des infections périnatales à streptocoques du groupe B.Melin, Pierrette ![]() Scientific conference (2000, October 05) Detailed reference viewed: 4 (1 ULg) L'influence des réglementations d'ordre public sur la validité des contratsDelnoy, Michel ![]() in Immobilier (2000), 17 Detailed reference viewed: 19 (0 ULg) HST/STIS Observations of a Dawn Auroral Storm on Jupiter; ; et al in Bulletin of the American Astronomical Society (2000, October 01) The HST/STIS recorded a detailed time series of images and spectra of the UV emissions from a dawn auroral storm on Jupiter on 21 Sept. 1999. The images show complex and evolving fine structure in the ... [more ▼] The HST/STIS recorded a detailed time series of images and spectra of the UV emissions from a dawn auroral storm on Jupiter on 21 Sept. 1999. The images show complex and evolving fine structure in the storm, while the emission center remained along the main oval and near dawn in magnetic local time. We serendipitously recorded low resolution UV spectra of the north-south spatial distribution of the auroral emissions. These spectra show far stronger hydrocarbon absorptions than observed in any previous auroral spectra. This indicates an unusually deep penetration of the incident primary particles with respect to the neutral atmosphere, and correspondingly high energy of the primary particles. We can thus use these spectra to identify many complex hydrocarbons in Jupiter's auroral atmosphere which are not normally measured in auroral spectra. These results will be presented along with model fits to the spectra derived both from fitting the observed hydrocarbon absorption features and from comparison with a photochemical model for the expected composition of the auroral atmosphere. This research has been supported by grant GO-8171.01-97A from the Space Telescope Science Institute to the University of Michigan. [less ▲] Detailed reference viewed: 7 (1 ULg) A fluorescence model of the C[SUB]3[/SUB] radical in comets; Arpigny, Claude ; et alin Bulletin of the American Astronomical Society (2000, October 01) The fluorescence spectrum of the C[SUB]3[/SUB] radical in comets is investigated. A theoretical model which takes into account the rotational structure and the different vibrational levels of the bending ... [more ▼] The fluorescence spectrum of the C[SUB]3[/SUB] radical in comets is investigated. A theoretical model which takes into account the rotational structure and the different vibrational levels of the bending mode ν [SUB]2[/SUB] involved in the emision of the 4050 à \ group, is elaborated. This model is used to interpret high-resolution spectra of some recent comets. The agreement between observed and theoretical spectra is satisfactory with some realistic assumptions on the electronic oscillator strength and the dipole moment derivative, which determine the relative importance of the rotation-vibration transitions. Different synthetic spectra which show the influence of the Swings effect and the consequences of the change in the heliocentric distance are also calculated and are presented. [less ▲] Detailed reference viewed: 4 (1 ULg) The isotope ratios [SUP]12[/SUP]C/[SUP]13[/SUP]C and [SUP]14[/SUP]N/[SUP]15[/SUP]N in comet C/1995 O1 (Hale-Bopp)Arpigny, Claude ; ; Manfroid, Jean et alin Bulletin of the American Astronomical Society (2000, October 01) The abundance ratios of stable isotopes of the light elements in comets may provide clues of cosmogonical significance. Measuring isotopic ratios in an optical cometary spectrum is, however, a rather ... [more ▼] The abundance ratios of stable isotopes of the light elements in comets may provide clues of cosmogonical significance. Measuring isotopic ratios in an optical cometary spectrum is, however, a rather difficult task for different reasons. Such measurements require, in particular, very high spectral resolution and are feasible so far only on bright objects. In 1997 we observed comet Hale-Bopp with the 2.6 m Nordic Optical Telescope on La Palma, Canary Islands, with a view to estimating the [SUP]12[/SUP]C/[SUP]13[/SUP]C abundance ratio. About twenty high-resolution (λ /Πλ ~ 70000) spectra of the strong CN Violet (0,0) band were secured with the SOFIN spectrograph from 7 to 13 April. The heliocentric and geocentric distances of the comet were then close to 0.9 AU and 1.4 AU, respectively. While the data do show the expected lines of the [SUP]13[/SUP]C[SUP]14[/SUP]N isotopic molecule, we have been surprised to find in addition a number of very weak features, which are real and turn out to be positioned very near to the theoretical wavelengths of lines pertaining to the R branch of [SUP]12[/SUP]C[SUP]15[/SUP]N. After a short description of the reduction and analysis of the data our paper discusses the results derived for [SUP]12[/SUP]C/[SUP]13[/SUP]C and [SUP]14[/SUP]N/[SUP]15[/SUP]N as well as their possible implications. We also present a brief review of the carbon and nitrogen isotopic ratios in various solar system objects and consider the question whether any nucleosynthesis site(s) is (are) known where pairs of values similar to those we measure in comet Hale-Bopp could be produced. [less ▲] Detailed reference viewed: 9 (1 ULg) Reactivity of functional SAN toward coreactive EPR-g-MA at planar interface; ; et al in Journal of Polymer Science. Part A, Polymer Chemistry (2000), 38(19), 3682-3689 The grafting kinetics of reactive poly(styrene-co-acrylonitrile) (SAN) onto EPR-g-MA was studied under isothermal conditions, at the planar interface of an SAN/ethylene-propylene rubber (EPR) bilayer film ... [more ▼] The grafting kinetics of reactive poly(styrene-co-acrylonitrile) (SAN) onto EPR-g-MA was studied under isothermal conditions, at the planar interface of an SAN/ethylene-propylene rubber (EPR) bilayer film in relation to the type of reactive groups, NH2 versus carbamate (which is an amine precursor), attached to SAN. The amount of SAN chemically bound to EPR chains at the interface was estimated by selectively washing off the unreacted SAN chains before X-ray photon spectroscopic analysis of the released surface. It is clear that the mutual reactivity of the reactive groups, i.e., the NH2-MA pair versus the carbamate-MA pair, has a decisive effect on the amount of SAN that reacts with EPR-g-MA at the interface. In case of SAN-carb, the grafting reaction is controlled by the thermolysis of the carbamate groups into primary amines. [less ▲] Detailed reference viewed: 15 (4 ULg) Contribution à l’étude de la fonction musculaire du sujet fibromyalgiqueMaquet, Didier ; Croisier, Jean-Louis ; Renard, Cindy et alin Actes du symposium « Evidence Based Physiotherapy » de la Fédération Nationale des Docteurs et Licenciés en Kinésithérapie (2000, October) Detailed reference viewed: 12 (1 ULg) "L'enregistrement des entrepreneurs sous son aspect solidarité"Moreau, Pierre ![]() in Le point sur le droit des sûretés (2000) Detailed reference viewed: 9 (3 ULg) Adaptive Applications over Active Networks: Case Study on Layered Multicast; Leduc, Guy ![]() in IP Networks Versus conventional Switched Networks (2000, October) In this paper we study the potential and limitations of active networks in the context of adaptive applications. We present a survey of active networking research applied to adaptive applications, and a ... [more ▼] In this paper we study the potential and limitations of active networks in the context of adaptive applications. We present a survey of active networking research applied to adaptive applications, and a case study on a layered multicast active application. This active application is a congestion control protocol that selectively discards data in the active routers, and prunes multicast tree branches affected by persistent congestion. Our first results indicate that active networks can indeed help such an application to adapt to heterogeneous receivers, with a minimum amount of state overhead, equivalent to that of a single IP multicast group. [less ▲] Detailed reference viewed: 6 (1 ULg) Etude sur modèle réduit hydraulique de l'évacuateur de crue du barrage de l'Oued Lag (Algérie)Lejeune, André ; Pirotton, Michel ; Erpicum, Sébastien ![]() Report (2000) Detailed reference viewed: 34 (2 ULg)![]() Rééducation raisonnée des lésions opérées du ligament croisé antérieur du genouCroisier, Jean-Louis ; Forthomme, Bénédicte ; Huskin, Jean-Pierre et alin Kiné Acta (2000), 356 Detailed reference viewed: 46 (13 ULg)![]() Le cas clinique du mois. A propos d'une presentation inhabituelle de syndrome cave superieur; Martinez, Christophe ; Ghuysen, Alexandre et alin Revue Médicale de Liège (2000), 55(10), 905-9 We report the case of a 48-year-old man who was admitted to our emergency department because of a superior vena caval syndrome from which the symptoms occurred only during exercise. His past history ... [more ▼] We report the case of a 48-year-old man who was admitted to our emergency department because of a superior vena caval syndrome from which the symptoms occurred only during exercise. His past history included an episode of lower limb deep venous thrombosis. Because an atrio-ventricular partial block was fortuitously evidenced, the patient was submitted to a pacemaker insertion. A few years later, the patient suffered from rapid dyspnea on exercise, associated with facial cyanosis and systemic hypotension. The exploration by phlebography evidenced that the inferior vena cava was completely obstructed. Therefore the venous return from the lower part of the body to right heart was obtained through hypertrophy of the vena azygos. In addition, the presence of cardiac pacing electrodes induced a stenosis at the level of the superior vena cava, just before its entrance into the right atrium. Such a venous network accounted for the occurrence of a chronic superior vena caval syndrome associated with peripheral arterial hypotension during exercise. Treatment consisted of a superior vena caval percutaneous transluminal balloon angioplasty followed by a Wallstent insertion. This procedure led to a correction of all hemodynamic abnormalities responsible for reported pathophysiological limitations to stress. [less ▲] Detailed reference viewed: 68 (3 ULg)![]() 2-(2-Oxoimidazolidinyl)Ethyl 2-Methylprop-2-EnoateSpirlet, Marie-Rose ; Desreux, Jean-François ; et alin Acta Crystallographica Section C-Crystal Structure Communications (2000), 56((Pt 10)), 1258-9 In the crystal structure of the title compound, C(9)H(14)N(2)O(3), the molecules are linked by N-H.O=C bonds into chains parallel to [001]. Large crystals are readily obtained, presumably because of the ... [more ▼] In the crystal structure of the title compound, C(9)H(14)N(2)O(3), the molecules are linked by N-H.O=C bonds into chains parallel to [001]. Large crystals are readily obtained, presumably because of the hydrogen bonds and an energetically stable conformation of the molecule. [less ▲] Detailed reference viewed: 36 (5 ULg) "Freud chez les didacticiens: de la gram-mère castratrice à l'inconscient grammatical"Defays, Jean-Marc ![]() Conference (2000, October) Detailed reference viewed: 24 (2 ULg) Comparative Evaluation of Four Detectors in the High-Performance Liquid Chromatographic Analysis of Chiral Nonaromatic Alcohols; ; et al in Journal of Chromatographic Science (2000), 38(10), 450-7 A comparative evaluation of ultraviolet, polarimetric, refractive index, and evaporative light-scattering detection coupled with high-performance liquid chromatography has been developed for the ... [more ▼] A comparative evaluation of ultraviolet, polarimetric, refractive index, and evaporative light-scattering detection coupled with high-performance liquid chromatography has been developed for the separation and quantitation of the enantiomers of chiral nonaromatic alcohols, some of which are intermediates in the synthesis of chiral drugs. (R,S)-3-tert-butylamino-1,2-propanediol; (R,S)-glycidol; and (R,S)-1-(4-morpholino)-2-octanol are selected as model compounds in order to compare the detection sensitivity and the linearity of the response with the four detectors. Separation of the enantiomers is performed using chiral stationary phases in normal-phase liquid chromatography. A one-day validation is achieved for (S)-3-tert-butylamino-1,2-propanediol with each detector, and limits of quantitation are determined for the three compounds. Advantages and limitations of the four detectors are discussed. [less ▲] Detailed reference viewed: 8 (1 ULg) Die Wirklichkeit der Ränder –Antisemitisches als Realismus der Marginalien in der Literatur der JahrhundertwendePontzen, Alexandra ![]() Scientific conference (2000, October) Detailed reference viewed: 3 (0 ULg) Multicriteria and multiactors aspects of an interactive tool aiding to sketch the building envelope during the first stages of the architectural designHauglustaine, Jean-Marie ![]() Conference (2000, October) The main objective of the present study is to introduce a rational method of aiding to design the envelope of a building, during the sketch design. The design method has for both objectives the respect of ... [more ▼] The main objective of the present study is to introduce a rational method of aiding to design the envelope of a building, during the sketch design. The design method has for both objectives the respect of building costs (for the construction itself and in use), and the improvement of the energy performance. In the multicriteria and multiactors context, this interactive tool is using decision-making aids, in order to improve the architectural response to the client’s and regulations requirements, while aiding: - the project authors in their conception tasks, by making up the project architectural forces, in accordance with the actors’ objectives; - and the client in his participation in the multiple partners negotiation. [less ▲] Detailed reference viewed: 28 (0 ULg) |
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