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See detailSerotype distribution of invasive Streptococcus agalactiae isolated from neonates and adults in Belgium over a 4-year period (1995-1999)
MELIN, Pierrette ULiege; De Mol, Patrick ULiege

in Martin, Diana R.; Tagg, John R. (Eds.) Streptococci and Streptococcal Diseases Entering the New Millenium - Proceeding of the XIV LISSSD (2000, November)

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See detailUtilisation de la télédétection pour le suivi des parcours en zone agro-pastorale sahélienne
Djaby, Bakary ULiege

Master of advanced studies dissertation (2000)

L'importance des terres de parcours au Sahel a depuis les sécheresses, favorisées l'observation des ressources pastorales par la télédétection basse résolution. Parmi les indices de végétation issus des ... [more ▼]

L'importance des terres de parcours au Sahel a depuis les sécheresses, favorisées l'observation des ressources pastorales par la télédétection basse résolution. Parmi les indices de végétation issus des images fournies par les différents senseurs, le NDVI est le plus couramment utilisé. Plusieurs travaux ont montré que cet indice est affecté par les variations des propriétés spectrales des sols. Cette caractéristique limite la détection de la végétation dans les milieux à couvert végétal faible comme en zone agropastorale sahélienne. Afin de pallier cette insuffisance du NDVI, plusieurs autres indices ont vu le jour comme le TSAVI dont les caractéristiques se sont montrées performantes en milieu expérimental pour le suivi de la végétation éparse. Au cours de ce travail, le TSAVI est élaboré et utilisé en mode opérationnel en comparaison avec le NDVI. Les deux indices utilisés sont issus des images de SPOT-VEGETATION, le nouveau senseur européen opérationnel depuis 1998. Cette comparaison est faite à travers l'évolution au cours de la saison des deux indices et l'évaluation de la phytomasse herbacée dans un milieu où l'occupation des sols est connue. Les résultats obtenus montrent que le TSAVI diffère très peu du NDVI au cours de la période de végétation active. Les différences observées résident dans la capacité du TSAVI à identifier les zones d'émergence précoce de la végétation, en début de saison des pluies. Dans une classification supervisée avec la signature indiciaire des sols de la région du Fakara, le TSAVI se montre plus performant avec une erreur d'omission inférieure de 10% à celle du NDVI. Dans l'évaluation de la phytomasse herbacée, les relations obtenues montrent que le NDVI est plus indiqué que le TSAVI. Malgré l'utilisation de données sur l'occupation des sols, les relations obtenues entre les indices et les masses végétales sont faibles. Cette faiblesse des relations est en partie liée au morcellement du territoire en milieu agropastoral sahélien. En revanche, dans les zones qui apparaissent homogènes, les résultats indiquent des liaisons fortes entre les indices et la masse végétale des mauvaises herbes. Les zones agropastorales du Sahel semblent plus indiquées dans un suivi qualitatif avec la télédétection basse résolution. La complexité de l'occupation des sols liée à plusieurs facteurs peut cependant être abordée avec une combinaison télédétection haute résolution et basse résolution pour une amélioration de l'information sur la sécurité alimentaire au Sahel. [less ▲]

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See detailDifferences in Experimental Virulence of Bovine Viral Diarrhoea Viral Strains Isolated from Haemorrhagic Syndromes
Hamers, C.; Couvreur, B.; Dehan, Pierre ULiege et al

in Veterinary Journal (2000), 160(3), 250-8

In the late 1980s, a new hypervirulent and epidemic form of bovine viral diarrhoea virus (BVDV) infection appeared in North America. A similar but sporadic syndrome was later reported in Europe. To ... [more ▼]

In the late 1980s, a new hypervirulent and epidemic form of bovine viral diarrhoea virus (BVDV) infection appeared in North America. A similar but sporadic syndrome was later reported in Europe. To compare the pathogenic characters of the North American and European hypervirulent strains, we inoculated BVDV naive calves with BVDV strains isolated from haemorrhagic syndromes originating in Belgium, France and the USA. The experimental procedure comprised daily clinical examination and measurement of blood and virological parameters.The American BVD890/256 strain induced severe thrombocytopaenia, profuse diarrhoea and pneumonia in all calves, indicating that hypervirulent BVDV could be the primary infectious agent of pneumonia. Interestingly, a strong correlation was observed between the intense viraemia and a decreased platelet count. None of the European strains tested induced significant pathological signs, although isolated from cases presenting haemorrhagic syndrome. [less ▲]

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See detailMesure de vibrations par holographie dynamique multi-expositions
Georges, Marc ULiege; Thizy, Cédric ULiege; Lemaire, Philippe et al

in Actes du Premier colloque francophone Méthodes et Techniques Optiques pour l'Industrie (2000, November)

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See detailPropriété intellectuelle : vers une exception à l’épuisement communautaire?
Munoz, Rodolphe ULiege

in Journal des Tribunaux Droit Européen (2000), 73

La théorie de l’épuisement empêche une entreprise de s’opposer à la commercialisation d’un produit qui a été écoulé sur un autre marché. L’épuisement est dit "communautaire" ou régional: la protection ne ... [more ▼]

La théorie de l’épuisement empêche une entreprise de s’opposer à la commercialisation d’un produit qui a été écoulé sur un autre marché. L’épuisement est dit "communautaire" ou régional: la protection ne peut être invoquée dans un Etat membre lorsque le produit a déjà été mis sur le marché dans un autre pays de la Communauté. La jurisprudence analysée dans cet article indique que l’épuisement pourrait devenir mondial. Aucune firme ne pourrait alors empêcher l’écoulement d’un produit commercialisé dans un pays tiers. Les vendeurs pourraient écouler dans la Communauté des produits achetés moins cher à l’étranger. Cela serait particulièrement intéressant pour les produits électroniques, qui sont traditionnellement chers en Europe. Le processus entraînerait, à moyen terme, une diminution des prix sur le continent européen. [less ▲]

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See detailComment je traite ... le myelome multiple refractaire par thalidomide
Scerbo, F.; Matus, G.; Sautois, Brieuc ULiege et al

in Revue Médicale de Liège (2000), 55(11), 970-3

Despite the use of high-dose chemotherapy with autologous hematopoietic stem cell transplantation, multiple myeloma remains largely uncurable. Indeed complete remission rate is about 50% and median ... [more ▼]

Despite the use of high-dose chemotherapy with autologous hematopoietic stem cell transplantation, multiple myeloma remains largely uncurable. Indeed complete remission rate is about 50% and median survival reaches 5 years without plateau. Recently thalidomide has been identified as a promising agent. We report the clinical story of 2 patients with refractory myeloma that we treated successfully with thalidomide. [less ▲]

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See detailMMP-2 and MMP-9-Linked Gelatinolytic Activity in the Sputum from Patients with Asthma and Chronic Obstructive Pulmonary Disease
Cataldo, Didier ULiege; Munaut, Carine ULiege; Noël, Agnès ULiege et al

in International Archives of Allergy & Immunology (2000), 123(3), 259-67

BACKGROUND: The course of asthma and chronic obstructive pulmonary disease (COPD) is associated with bronchial morphological changes. Metalloproteinases are thought to play a role in these structural ... [more ▼]

BACKGROUND: The course of asthma and chronic obstructive pulmonary disease (COPD) is associated with bronchial morphological changes. Metalloproteinases are thought to play a role in these structural changes. METHODS: We studied the gelatinolytic activity present in the induced sputum from 20 patients with asthma, 20 with COPD and 19 healthy controls. The assessment of gelatinolytic activity was performed by quantitative zymography, and gelatinolytic species were identified by Western blot analysis. Tissue inhibitor of metalloproteinase-1 (TIMP-1) was detected by reverse zymography and ELISA. RESULTS: From zymography, we found significantly higher gelatinolytic activity linked to pro-matrix metalloproteinase-9 (pro-MMP-9) in the sputum from asthmatics (p < 0.0001) and COPD patients (p < 0.0001) compared to the control group. Furthermore, the activated form of MMP-9 (85 kD) was found in the sputum from 60% of asthmatics and 85% of COPD patients, but was absent in that of control subjects (p < 0.0001). Importantly, although less frequently detectable than pro-MMP-9, pro- MMP-2 (72 kD) was found more frequently in asthmatics (50%) than in control subjects (5%) (p < 0. 005). We also described two unusual gelatinolytic species of 45 and 120 kD and showed that they derived from MMP-9 according to their ability to bind gelatin and anti-MMP-9 antibody. Levels of TIMP-1 were higher in asthmatics (p < 0.05) and COPD patients (p < 0.05) than in controls. CONCLUSION: Asthmatics and COPD patients display an increased gelatinolytic activity linked to MMP-2 and MMP-9 and higher levels of TIMP-1 in their sputum. [less ▲]

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See detailPaul van Ostaijen
Spinoy, Erik ULiege

in Brems, Hugo; Van Deel, Tom; Zuiderent, Ad (Eds.) Kritisch lexicon van de moderne Nederlandstalige literatuur (2000)

This is a survey of the life and work of the important Flemish expressionist poet Paul van Ostaijen.

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See detailInteractive tool aiding the actors involved in a building project, to sketch the envelope during the preliminary stages of the design, while taking into account their own objectives, in a multicriteria and multiactors approach
Hauglustaine, Jean-Marie ULiege

in Mangin, Jean-Claude; Miramond, Marcel (Eds.) 2e conférence internationale sur l'Aide à la Décision dans le domaine Génie Civil et Urbain (2000, November)

The present study has for objective to introduce, during the sketch design, a rational method of aiding to design the envelope of a building, targeting the respect of costs (for the construction and in ... [more ▼]

The present study has for objective to introduce, during the sketch design, a rational method of aiding to design the envelope of a building, targeting the respect of costs (for the construction and in use of the building) and the improvement of the energy performance of the project. In respect of the multicriteria and multiactors context of any building project, an interactive tool is being developed, which is using decision-making aids, in order to improve the architectural response to the client’s and regulations requirements, while aiding; - the client: in the expression of his requirements and in his participation to the multiple partners negotiation; - the project authors: in their elaboration of the parametric and graphic forces of the architectural project, they can develop in accordance with the actors’ objectives. Permanently informed about the project performances, the user may go, as he pleases, in the parametric or in the graphic module, in order to reach the most preferred compromise. [less ▲]

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See detailMédias, finance et industrie : haro sur la démocratie
Geuens, Geoffrey ULiege

Article for general public (2000)

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See detailProduction of Bovine Herpesvirus Type 1-Seronegative Latent Carriers by Administration of a Live-Attenuated Vaccine in Passively Immunized Calves
Lemaire, Mylène; Meyer, Gilles; Baranowski, Eric et al

in Journal of Clinical Microbiology (2000), 38(11), 4233-8

The consequences of the vaccination of neonatal calves with the widely used live-attenuated temperature-sensitive (ts) bovine herpesvirus type 1 (BHV-1) were investigated. The ts strain established acute ... [more ▼]

The consequences of the vaccination of neonatal calves with the widely used live-attenuated temperature-sensitive (ts) bovine herpesvirus type 1 (BHV-1) were investigated. The ts strain established acute and latent infections in all vaccinated calves either with or without passive immunity. Four of seven calves vaccinated under passive immunity became clearly BHV-1 seronegative by different serological tests, as did uninfected control calves after the disappearance of maternal antibodies, and they remained so for long periods. A cell-mediated immune response was detected by a BHV-1 gamma interferon assay, but this test failed to detect the seronegative latent carriers (SNLCs). While they are not detected, SNLCs represent a threat for BHV-1-free herds or countries. This study demonstrates that SNLCs can be easily obtained by inoculation with a live-attenuated BHV-1 under passive immunity and that latent carrier animals without any antibody do exist. Consequently, this situation could represent a good model to experimentally produce SNLCs. [less ▲]

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See detailALPS/ULSAP Software for Ultimate Strength Design of Steel Grillages under Combined Loads
Rigo, Philippe ULiege; Toderan, C.; Hughes et al

in SIMOUEST’2000, European Conference, Marine Technology (2000, November)

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See detailLBR-5, a Ship Hull Optimization Tool
Rigo, Philippe ULiege; Hage, André ULiege

in SIMOUEST’2000, European Conference, Marine Technology (2000, November)

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See detailAre Cities of Northern Europe at Risk ?
Plumier, André ULiege; Jongmans, Denis

in Proceedings of the Workshop Mitigation of Seismic Risk - Support to recently Affected European Countries (2000, November)

A benchmark study on seimic risk has been realised on Liege, Belgium, at the request of the Regional Authority. Its main interest is that it deals with the seismic risk of a city in a low seismicity ... [more ▼]

A benchmark study on seimic risk has been realised on Liege, Belgium, at the request of the Regional Authority. Its main interest is that it deals with the seismic risk of a city in a low seismicity region. The work involves a hazard study based on the recently defined map of seismicity of Belgium, the definition of the individual vulnerability of buildings, the combination of hazard and vulnerability to define risk and static evaluations of connecting details in non engineered structures. For the evaluation of vulnerability, a simplified screening method has been defined. The main conclusion is that in regions where the Peak Ground Acceleration is higher than 0,1g and the building stock does not possess good structural quality, the seismic risk may be considered high. [less ▲]

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See detailSeismic Resistant Composite Structures
Mazzolani, F.; Gioncu, V.; Akiyama, H. et al

in Mazzolani, F.; Gioncu, V. (Eds.) Seismic Resistant Steel Structures (2000)

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See detailReactive compatibilization of SAN/EPR blends: Effect of rubber content and reactivity of the SAN functional groups
Pagnoulle, Christophe; Martin, Philippe; Jérôme, Robert ULiege

in Macromolecular Chemistry and Physics (2000), 201(16), 2181-2194

SAN containing 20 wt.-% reactive SAN-X was melt blended with EPDM containing 50 wt.-% maleic anhydride EPR grafted chains (EP-g-MA). The rubber content was changed from 15 to 80 wt.-%, and 2 types of ... [more ▼]

SAN containing 20 wt.-% reactive SAN-X was melt blended with EPDM containing 50 wt.-% maleic anhydride EPR grafted chains (EP-g-MA). The rubber content was changed from 15 to 80 wt.-%, and 2 types of reactive groups (X) were attached to SAN (0.028 mol X/ wt.-%), i. e. primary amines and carbamates which are primary amine precursors at the processing temperature. Phase morphology, tensile properties and impact strength depend not only on the rubber content but also on the relative reactivity of the amine and the carbamate groups towards maleic anhydride, in a strong dependence on the reaction rate and the reaction completeness. The dispersion mechanism has been discussed, including formation of sub-inclusions. Dependence of the impact resistance on the rubber phase content for non-reactive blends (□) and blends modified by SAN-NH2 (;) and SAN-carb (o), respectively. [less ▲]

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See detailHeavy Metals Contamination and Body Condition of Wintering Guillemots (Uria Aalge) at the Belgian Coast from 1993 to 1998
Debacker, Virginie ULiege; Jauniaux, Thierry ULiege; Coignoul, Freddy ULiege et al

in Environmental Research (2000), A84(3), 310-317

A sample of 166 common guillemots (Uria aalge) recovered from Belgian beaches during five wintering seasons, from 1993-1994 to 1997-1998, were examined. At necropsy, postmortem examination including body ... [more ▼]

A sample of 166 common guillemots (Uria aalge) recovered from Belgian beaches during five wintering seasons, from 1993-1994 to 1997-1998, were examined. At necropsy, postmortem examination including body mass, fat reserves, presence or not of intestinal contents, eventual status of oiling, and pathological changes (cachexia, acute hemorrhagic gastroenteropathy (GEAH)) was attributed to each individual. Mild to severe cachexia, a pathology characterized by moderate to severe atrophy of the pectoral muscle as well as reduced amounts or absence of subcutaneous and/or abdominal fat, was observed for most specimens (85.8%). Heavy metal analyses (Cu, Zn, Fe, Cd, Ni, Cr, and Pb) of the tissues (typically liver, kidney, and pectoral muscle) were performed, and total lipids were determined (liver and pectoral muscle). The guillemots collected at the Belgian coast exhibited higher Cu and Zn concentrations compared to individuals collected in more preserved areas of the North Sea such as the northern colonies. A general decrease of their total body mass as well as liver, kidney, and pectoral muscle mass was associated to increasing cachexia severity. Moreover, significantly increasing heavy metal levels (Cu and Zn) in the tissues as well as depleted muscle lipid contents were observed parallel to increasing cachexia severity. On the contrary the organs' total metal burden barely correlates to this status. These observations tend to indicate a general redistribution of heavy metals within the organs as a result of prolonged starvation and protein catabolism (cachectic status). Such a redistribution could well be an additional stress to birds already experiencing stressfull conditions (starvation, oiling). [less ▲]

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See detailThe Dppa Gene of Bacillus Subtilis Encodes a New D-Aminopeptidase
Cheggour, Abdelatif; Fanuel, Laurence; Duez, Colette ULiege et al

in Molecular Microbiology (2000), 38(3), 504-13

Different strains of Bacillus were screened for their ability to hydrolyse D-alanyl-p-nitroanilide. Activity was detected in Bacillus pumilus, Bacillus brevis, Bacillus licheniformis 749I and Bacillus ... [more ▼]

Different strains of Bacillus were screened for their ability to hydrolyse D-alanyl-p-nitroanilide. Activity was detected in Bacillus pumilus, Bacillus brevis, Bacillus licheniformis 749I and Bacillus subtilis 168. The last strain was the best producer and was selected for the production and purification of the enzyme. The determination of the N-terminal sequence identified the enzyme as the product of the dppA gene (previously named dciAA) belonging to the dipeptide ABC transport (dpp) operon expressed early during sporulation. Open reading frames (ORFs) encoding putative related proteins were found in the genomes of a variety of Archaea and both sporulating and non-sporulating bacteria. The enzyme behaves as a D-aminopeptidase and represents the prototype of a new peptidase family. Among the tested substrates, the highest activities were found with D-Ala-D-Ala and D-Ala-Gly-Gly. The active enzyme behaves as an octamer of identical 30 kDa subunits. It exhibits a broad pH optimum, extending between pH 9 and 11. It is reversibly inhibited in the presence of Zn2+ chelators, and the sequence comparisons highlight the conservation of potential Zn-binding residues. As it has been shown by others that null mutations in the dpp operon do not inhibit spore formation, the physiological role of DppA is probably an adaptation to nutrient deficiency. [less ▲]

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See detailPowerful Alternative Asymmetric Catalytic Dihydroxylation of Olefins
Colaux, Catherine ULiege; Krief, Alain

Poster (2000, November)

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