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See detailUrinary excretion of high Mr PEG (4000 Da) in rats
Nollevaux, G; Loret, S; Barakat, I et al

Conference (2000, November 18)

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See detailNf-Kappab Activation in Response to Toxical and Therapeutical Agents: Role in Inflammation and Cancer Treatment
Bours, Vincent ULg; Bonizzi, Giuseppina; Bentires-Alj, Mohamed et al

in Toxicology (2000), 153(1-3), 27-38

The NF-kappaB transcription factor is ubiquitously expressed and controls the expression of a large number of genes. Experimental data clearly indicate that NF-kappaB is a major regulator of the ... [more ▼]

The NF-kappaB transcription factor is ubiquitously expressed and controls the expression of a large number of genes. Experimental data clearly indicate that NF-kappaB is a major regulator of the inflammatory reaction by controlling the expression of pro-inflammatory molecules in response to cytokines, oxidative stress and infectious agents. We demonstrated that NF-kappaB activation by IL-1beta follows three distinct cell-specific pathways. Moreover, our studies indicated that in one model of inflammatory diseases, horse recurrent airway obstruction (RAO), the extent of NF-kappaB basal activity correlates with pulmonary dysfunction. Another role of NF-kappaB activity protects cancer cells against apoptosis and could participate in the resistance to cancer treatment. However, we did not observe any increased cytotoxicity after treatment with anticancer drugs or TNF-alpha of cells expressing a NF-kappaB inhibitor. Therefore, we can conclude that the inhibition of apoptosis by NF-kappaB is likely to be cell type and stimulus-dependent. Further studies are required to determine whether NF-kappaB could be a target for anticancer treatments. [less ▲]

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See detailMechanisms of Persistent Nf-Kappa B Activity in the Bronchi of an Animal Model of Asthma
Bureau, Fabrice ULg; Delhalle, Sylvie; Bonizzi, Giuseppina et al

in Journal of Immunology (2000), 165(10), 5822-5830

In most cells trans-activating NF-kappaB induces many inflammatory proteins as well as its own inhibitor, IkappaB-alpha, thus assuring a transient response upon stimulation. However, NF-kappaB-dependent ... [more ▼]

In most cells trans-activating NF-kappaB induces many inflammatory proteins as well as its own inhibitor, IkappaB-alpha, thus assuring a transient response upon stimulation. However, NF-kappaB-dependent inflammatory gene expression is persistent in asthmatic bronchi, even after allergen eviction. In the present report we used bronchial brushing samples (BBSs) from heaves-affected horses (a spontaneous model of asthma) to elucidate the mechanisms by which NF-kappaB activity is maintained in asthmatic airways. NF-kappaB activity was high in granulocytic and nongranulocytic BBS cells. However, NF-kappaB activity highly correlated to granulocyte percentage and was only abrogated after granulocytic death in cultured BBSs. Before granulocytic death, NF-kappaB activity was suppressed by simultaneous addition of neutralizing anti-IL-1beta and anti-TNF-alpha Abs to the medium of cultured BBSs. Surprisingly, IkappaB-beta, whose expression is not regulated by NF-kappaB, unlike IkappaB-alpha, was the most prominent NF-kappaB inhibitor found in BBSs. The amounts of IkappaB-beta were low in BBSs obtained from diseased horses, but drastically increased after addition of the neutralizing anti-IL-1beta and anti-TNF-alpha Abs. These results indicate that sustained NF-kappaB activation in asthmatic bronchi is driven by granulocytes and is mediated by IL-1beta and TNF-alpha. Moreover, an imbalance between high levels of IL-1beta- and TNF-alpha-mediated IkappaB-beta degradation and low levels of IkappaB-beta synthesis is likely to be the mechanism preventing NF-kappaB deactivation in asthmatic airways before granulocytic death. [less ▲]

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See detailRadioimmunoassay measurement of insulin-like growth factor-I in camels: effects of anticoagulants and body condition score in suckling female.
Hammadi, M.; Khorchani, T.; Moslah, M. et al

in Proceedings of the 2nd Belgian Workshop on Animal Endocrinology (2000, November 15)

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See detailA homologous radioimmunoassay for quantification of insulin-like growth factor-binding protein-3 in blood from cattle.
Renaville, Robert ULg; Bertozzi, Carlo; Hornick, J. L. et al

in Proceedings of the 2nd Belgian Workshop on Animal Endocrinology. (2000, November 15)

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See detailAlimentation et fertilité en Blanc Bleu Belge
Beckers, Yves ULg

Conference given outside the academic context (2000)

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See detailPituitary Adenomas : Preoperative treatment of acromegaly
Beckers, Albert ULg

Scientific conference (2000, November 11)

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See detailLife Sciences in the Euregio Meuse-Rhine
Jérôme, Robert ULg; Klee, D; Koole, L et al

Conference (2000, November 09)

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See detailRapport d'atelier: Pratique d'orientation et représentation des études et des professions
Broonen, Jean-Paul ULg; Rozet, A.; Degrüne, A.

in Conseil général des Etudes; Orientation Universitaire; Guidance Etude (Eds.) et al Journée de l'Orientation. Réflexion sur le processus d'orientation et analyse des fondements des pratiques de l'orientation; valeurs sociales et vision politique sous-jacentes. Actes (2000)

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See detailApport de l'analyse sensorrielle dans l'étude d'aliments à texture diversifiée.
Blecker, Christophe ULg

Scientific conference (2000, November 08)

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See detailLa troponine, nouveau marqueur de l'infarctus du myocarde
Chapelle, Jean-Paul ULg

Conference (2000, November 06)

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See detailContrôle de congestion pour la transmission multipoint en couches
El Khayat, Ibtissam; Leduc, Guy ULg

Conference (2000, November 06)

Le contrôle de congestion en transmission multipoints est rendu difficile par l'hétérogénéité des récepteurs. En effet, pour la transmission vidéo par exemple, il serait peu raisonnable que l'émetteur ... [more ▼]

Le contrôle de congestion en transmission multipoints est rendu difficile par l'hétérogénéité des récepteurs. En effet, pour la transmission vidéo par exemple, il serait peu raisonnable que l'émetteur adapte son débit en fonction du récepteur le moins performant ou de celui qui subit temporairement la congestion la plus sévère. Pour contourner ce problème, l'émetteur peut émettre un flux structuré en couches, de telle sorte que la couche de base donne une qualité minimale et que les couches suivantes améliorent successivement cette qualité. L'algorithme de contrôle de congestion proposé est basé sur ce schéma. Il permet à chaque récepteur de sélectionner dynamiquement un sous-ensemble adéquat de couches en répondant aux objectifs suivants. Premièrement, l'algorithme doit être équitable vis-à-vis de TCP; ce qui signifie que les débits du flux multicouches reçu et celui d'un flux TCP placé dans les mêmes conditions doivent être plus ou moins les mêmes. Deuxièmement, les récepteurs doivent être suffisamment coordonnés pour qu'une congestion résultant de l'ajout d'une couche par l'un d'eux ne puisse être interprétée par un autre récepteur comme une congestion résultant de ses propres décisions ou d'un trafic perturbateur. Enfin, lorsque deux sessions multicouches empruntent un même goulet, nous souhaitons que les récepteurs obtiennent le même débit, ce qui signifiera en général des nombres de couches différents si les débits des couches sont distincts. [less ▲]

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See detailAmbulatory blood pressure monitoring : a tool or a toy?
Rorive, Georges ULg; Krzesinski, Jean-Marie ULg

Scientific conference (2000, November 04)

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See detailMulticulturalism and Ethnicity in Europe
Martiniello, Marco ULg

Scientific conference (2000, November 02)

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See detailLinear and nonlinear Rayleigh-Bénard-Marangoni instability with surface deformations
Regnier, Vincent; Dauby, Pierre ULg; Lebon, Georgy ULg

in Physics of Fluids (2000), 12

Thermoconvective instabilities in a bilayer liquid-gas system with a deformed interface are investigated. In the first part of the work which is devoted to a linear approach, emphasis is put on the role ... [more ▼]

Thermoconvective instabilities in a bilayer liquid-gas system with a deformed interface are investigated. In the first part of the work which is devoted to a linear approach, emphasis is put on the role of the upper gas layer on the instability phenomenon. The condition to be satisfied by the gas to remain purely conductive is established. The so-called Oberbeck-Boussinesq approximation is discussed and its range of validity is carefully defined. Instead of the classical Rayleigh, Marangoni, crispation, and Galileo numbers, new dimensionless groups are introduced. A critical comparison with several previous works is made. The nonlinear analysis consists in studying the different convective patterns which can appear above the threshold. Particular attention is devoted to the shape of the interface and the so-called ``hybrid'' relief. The amplitude of the deformation is also determined and comparison with experimental data is discussed. [less ▲]

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See detailThe Old Halo metallicity gradient: the trace of a self-enrichment process
Parmentier, Geneviève ULg; Jehin, Emmanuel ULg; Magain, Pierre ULg et al

in Astronomy and Astrophysics (2000), 363

Based on a model of globular cluster self-enrichment published in a previous paper, we present an explanation for the metallicity gradient observed throughout the galactic Old Halo. Our self-enrichment ... [more ▼]

Based on a model of globular cluster self-enrichment published in a previous paper, we present an explanation for the metallicity gradient observed throughout the galactic Old Halo. Our self-enrichment model is based on the ability of globular cluster progenitor clouds to retain the ejecta of a first generation of Type II Supernovae. The key point is that this ability depends on the pressure exerted on the progenitor cloud by the surrounding protogalactic medium and therefore on the location of the cloud in the protoGalaxy. Since there is no significant (if any) metallicity gradient in the whole halo, we also present a review in favour of a galactic halo partly built via accretions and mergers of satellite systems. Some of them bear their own globular clusters and therefore ``contaminate'' the system of globular clusters formed ``in situ'', namely within the original potential well of the Galaxy. Therefore, the comparison between our self-enrichment model and the observational data should be limited to the genuine galactic globular clusters, the so-called Old Halo group. [less ▲]

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See detailAmplitude equations and thermoconvective rolls far from the threshold
Dauby, Pierre ULg; Desaive, Thomas ULg

in Proceedings of the 53rd annual meeting of the division of fluid dynamics of the American physical society (2000, November 01)

Amplitude equations are used to show that third order harmonics of a basic roll convective pattern can appear in the highly nonlinear régime of Rayleigh-Bénard thermoconvection. The phenomenon is induced ... [more ▼]

Amplitude equations are used to show that third order harmonics of a basic roll convective pattern can appear in the highly nonlinear régime of Rayleigh-Bénard thermoconvection. The phenomenon is induced by the nonlinear interaction of the roll pattern with its second order harmonics, which were first generated by the quadratic nonlinearity due to the convective terms of the time derivatives in the field equations. Good qualitative agreement with experimental data is obtained with only 4 amplitude equations. More precise quantitative results are deduced by increasing the number of amplitude equations. Comparison with purely numerical calculations is also discussed. [less ▲]

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See detailPolarization holography reveals the nature of the grating in polymers containing azo-dye
Blanche, Pierre-Alexandre ULg; Lemaire, P. C.; Maertens, Christophe et al

in Optics Communications (2000), 185(1-3), 1-12

To study the origin of reversible holographic recording in three polymers containing the same azo-dye, we have measured the diffraction efficiency and analyzed the gratings characteristics for various ... [more ▼]

To study the origin of reversible holographic recording in three polymers containing the same azo-dye, we have measured the diffraction efficiency and analyzed the gratings characteristics for various writing beams polarizations. The amplitude of the holographic grating, as well as the ratio between index and absorption modulations, have been investigated by gratings shifting. The total amount of diffracted power and the diffraction efficiency versus the reading beam polarization has been measured by non-degenerated four waves mixing. These experiments have revealed that the molecular mechanisms of holographic recording in the studied compounds are different. The photoinduced orientation of the chromophores is predominant for C6-C11-DMNPAA; so, in C11-C6-DMNPAA (DMNPAA: 2,5-dimethyl-4-(p-nitrophenylazo)anisole), the refractive index variation comes from the presence of both trans and cis populations generated by photoisomerization. The behavior of the PVK:DMNPAA is included between these extreme cases since both phenomena act. [less ▲]

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See detailAn Optical Time Delay Estimate for the Double Gravitational Lens System B1600+434
Burud, I.; Hjorth, J.; Jaunsen, A. O. et al

in Astrophysical Journal (2000), 544

We present optical I-band light curves of the gravitationally lensed double QSO B1600+434 from observations obtained at the Nordic Optical Telescope (NOT) between 1998 April and 1999 November. The ... [more ▼]

We present optical I-band light curves of the gravitationally lensed double QSO B1600+434 from observations obtained at the Nordic Optical Telescope (NOT) between 1998 April and 1999 November. The photometry has been performed by simultaneous deconvolution of all the data frames, involving a numerical lens galaxy model. Four methods have been applied to determine the time delay between the two QSO components, giving a mean estimate of Deltat=51+/-4 days (95% confidence level). This is the fourth optical time delay ever measured. Adopting a Omega=0.3, Lambda=0 universe and using the mass model of Maller et al., this time delay estimate yields a Hubble parameter of H[SUB]0[/SUB]=52[SUP]+14[/SUP][SUB]-8[/SUB] km s[SUP]-1[/SUP] Mpc[SUP]-1[/SUP] (95% confidence level), where the errors include time delay as well as model uncertainties. There are time-dependent offsets between the two (appropriately shifted) light curves that indicate the presence of external variations due to microlensing. Based on observations made with the Nordic Optical Telescope, operated on the island of La Palma jointly by Denmark, Finland, Iceland, Norway, and Sweden, in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias. [less ▲]

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See detailCoordinated monitoring of the eccentric O-star binary Iota Orionis: the X-ray analysis
Pittard, Julian M; Stevens, Ian R; Corcoran, Michael F et al

in Monthly Notices of the Royal Astronomical Society (2000), 319

We analyse two ASCA observations of the highly eccentric O9 III+B1 III binary Iota Orionis obtained at periastron and apastron. Based on the assumption of a strong colliding-wind shock between the stellar ... [more ▼]

We analyse two ASCA observations of the highly eccentric O9 III+B1 III binary Iota Orionis obtained at periastron and apastron. Based on the assumption of a strong colliding-wind shock between the stellar components, we expected to see significant variation in the X-ray emission between these phases. The observations proved otherwise: the X-ray luminosities and spectral distributions were remarkably similar. The only noteworthy feature in the X-ray data was the hint of a proximity effect during periastron passage. Although this `flare' is of relatively low significance, it is supported by the notable proximity effects seen in the optical, and the phasing of the X-ray and optical events is in very good agreement. However, other interpretations are also possible. In view of the degradation of the SIS instrument and source contamination in the GIS data we discuss the accuracy of these results, and also analyse archival ROSAT observations. We investigate why we do not see a clear colliding-wind signature. A simple model shows that the wind attenuation to the expected position of the shock apex is negligible throughout the orbit, which poses the puzzling question of why the expected 1/D variation (i.e. a factor of 7.5) in the intrinsic luminosity is not seen in the data. Two scenarios are proposed: either the colliding-wind emission is unexpectedly weak such that intrinsic shocks in the winds dominate the emission, or, alternatively, the emission observed is colliding-wind emission but in a more complex form than we would naively expect. Complex hydrodynamical models are then analysed. Despite strongly phase-variable emission from the models, both are consistent with the observations. We find that if the mass-loss rates of the stars are low then intrinsic wind shocks could dominate the emission. However, when we assume higher mass-loss rates of the stars, we find that the observed emission could also be consistent with a purely colliding-wind origin. A summary of the strengths and weaknesses of each interpretation is presented. To distinguish between the different models X-ray observations with improved phase coverage will be necessary. [less ▲]

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