Mieux connaître sa voix

Conference given outside the academic context (1998)

Streptococcus agalactiae (dans rapport de surveillance des maladies infectieuses 1997)

Report (1998)

Morphometric Study of the Equine Navicular Bone: Variations with Breeds and Types of Horse and Influence of Exercise

in Journal of Anatomy (1998), 193((Pt 4)), 535-49

Navicular bones from the 4 limbs of 95 horses, classified in 9 categories, were studied. The anatomical bases were established for the morphometry of the navicular bone and its variations according to the ... [more ▼]

Navicular bones from the 4 limbs of 95 horses, classified in 9 categories, were studied. The anatomical bases were established for the morphometry of the navicular bone and its variations according to the category of horse, after corrections were made for front or rear limb, sex, weight, size and age. In ponies, navicular bone measurements were smallest for light ponies and regularly increased with body size, but in horses, navicular bone dimensions were smallest for the athletic halfbred, intermediate for draft horse, thoroughbreds and sedentary halfbreds and largest for heavy halfbreds. The athletic halfbred thus showed reduced bone dimensions when compared with other horse types. Navicular bones from 61 horses were studied histomorphometrically. Light horses and ponies possessed larger amounts of cancellous bone and less cortical bone. Draft horses and heavy ponies showed marked thickening of cortical bone with minimum intracortical porosity, and a decrease in marrow spaces associated with more trabecular bone. Two distinct zones were observed for the flexor surface cortex: an external zone composed mainly of poorly remodelled lamellar bone, disposed in a distoproximal oblique direction, and an internal zone composed mainly of secondary bone, with a lateromedial direction for haversian canals. Flexor cortex external zone tended to be smaller for heavy ponies than for the light ponies. It was the opposite for horses, with the largest amount of external zone registered for draft horses. In athletic horses, we observed an increase in the amount of cortical bone at the expense of cancellous bone which could be the result of reduced resorption and increased formation at the corticoendosteal junction. Cancellous bone was reduced for the athletic horses but the number of trabeculae and their specific surfaces were larger. Increased bone formation and reduced resorption could also account for these differences. [less ▲]

Alkoxyamine-mediated Controlled Radical Polymerization in Emulsion

Poster (1998, November)

Alkoxyamine-mediated Controlled Radical Polymerization in Emulsion is presented here.

Vers une formation initiale en didactique des langues germaniques axée sur l'articulation de la théorie et de la pratique didactiques

in Hiligsmann, Philippe (Ed.) ANBF-Nieuwsbrief (1998, November)

Selon G. Simons, le simple organigramme d'un cours de didactique spéciale véhicule une certaine représentation de ce que sont ou devraient être l'enseignement et l'apprentissage. Cette conception est ... [more ▼]

Selon G. Simons, le simple organigramme d'un cours de didactique spéciale véhicule une certaine représentation de ce que sont ou devraient être l'enseignement et l'apprentissage. Cette conception est progressivement intériorisée par les étudiants, dans le cas présent, de futurs enseignants en langues germaniques, et constitue un curriculum latent qui risque d'influencer (in)directement leur manière d'enseigner. Dans cette communication, G. Simons décrit et commente brièvement un ensemble de micro-réformes introduites dans la macro-structure méthodologique de la formation initiale en Didactique des Langues germaniques à l'Université de Liège de 1990 à 1998. Toutes ces micro-réformes poursuivent un seul et même objectif final : favoriser l'articulation de la théorie et de la pratique didactiques ou former des praticiens réfléchis. [less ▲]

tournois internationaux, SUPPORTERS, HOOLIGANS ET MESURES DE PREVENTION DANS LES STADES EN EUROPE

Report (1998)

Analyse de la nature, de la dynamique et du mode de fonctionnement des supporters européens, dont les noyaux durs, attachés à des équipes nationales (avec une attention particulière aux pays de l’Est ... [more ▼]

Analyse de la nature, de la dynamique et du mode de fonctionnement des supporters européens, dont les noyaux durs, attachés à des équipes nationales (avec une attention particulière aux pays de l’Est). Constitution d’une « typologie» sur les caractéristiques, comportements et habitudes des supporters internationaux. Analyse et évaluation de l’impact des stratégies de contrôle des supporters et des mesures de sécurité policières (maintien de l’ordre public), préventives (stewarding, fanprojects, animations) et organisationnelles (infrastructures, billetterie, vente d’alcool) mises en place dans les stades de football européens, notamment à l’occasion des tournois internationaux (Championnats d’Europe des Nations et Coupes du Monde). Propositions afin de transposer et adapter des stratégies d’intervention expérimentées avec des effets positifs à l’étranger pour l’organisation sécuritaire de l’Euro 2.000 [less ▲]

Evaluation of a Diphenylphosphorylazide-Crosslinked Collagen Membrane for Guided Bone Regeneration in Mandibular Defects in Rats

in Journal of Periodontology (1998), 69(11), 1238-46

In the present study, the potential of a diphenylphosphorylazide-crosslinked type I bovine collagen membrane was evaluated in the healing of mandibular bone defects applying the biological concept of ... [more ▼]

In the present study, the potential of a diphenylphosphorylazide-crosslinked type I bovine collagen membrane was evaluated in the healing of mandibular bone defects applying the biological concept of guided bone regeneration. The experiment was carried out on 25 Wistar rats. After exposing the mandibular ramus bilaterally, 5 mm diameter full-thickness circular bone defects were surgically created. While the defect on one side was covered by the membrane (experimental), the defect on the other side was left uncovered (control) before closure of the overlying soft tissues. The rats were sacrificed in groups of 5 after 7, 15, 30, 90, and 180 days of healing. Although at early stages of healing similar amounts of bone formation were observed in the experimental and control defects, after 1 month of healing, most of the experimental defects were completely closed with new bone, while in the control defects, only limited amounts of new bone were observed at the rims and in the lingual aspect of the lesions. In the 90- and 180-day animals, all experimental defects were completely closed, while in the control defects, no statistically significant increase in bone regeneration was observed. The increase in percentage of bone regeneration in the experimental defects was statistically significant between the 15-day specimens as compared with the 7-day specimens (P < 0.01) and likewise between 30-day and 15-day specimens (P < 0.001). It can be concluded that a DPPA-crosslinked collagen membrane yields biocompatibility, ad hoc mechanical hindrance, and handling characteristics suitable for guided bone regeneration applications in this experimental model. [less ▲]

Fgf-3 and Fgf-4 Elicit Distinct Oncogenic Properties in Mouse Mammary Myoepithelial Cells

in Oncogene (1998), 17(16), 2059-71

Fibroblast Growth Factors 3 (FGF-3) and 4 (FGF-4) were compared for the effects they each exert on EF43 mouse cells. This non-transformed mammary cell line appears to be myoepithelial mainly because it ... [more ▼]

Fibroblast Growth Factors 3 (FGF-3) and 4 (FGF-4) were compared for the effects they each exert on EF43 mouse cells. This non-transformed mammary cell line appears to be myoepithelial mainly because it expresses alpha-smooth muscle actin. The EF43 cells were infected with similar vectors that carry either the short fgf-3 sequence (the product of which goes into the secretory pathway), fgf-4 or the selection gene only as control. In syngeneic animals, EF43.fgf-3 cells were tumorigenic only when orthotopically implanted whereas EF43.fgf-4 cells invariably gave rise to aggressive tumors. However, both tumor types were metastatic as evidenced by the blue micrometastases observed when the implanted cells expressed lacZ. In vitro, the FGF-3 producing cells were strongly invasive in matrigel coated chambers whereas the EF43.fgf-4 cells only were invasive in type I-collagen gels. Interestingly, FGF-3 production greatly stimulated the synthesis of pro-MMP-9 (Matrix Metalloprotease-9) and, to a lesser extent, that of pro-MMP-2. FGF-3 also up-regulated the production of plasminogen activators. In contrast, FGF-4 had no effect on these secretions and the medium conditioned by the EF43.fgf-4 cells displayed the largest plasminogen activator-inhibitor activity. These results show that FGF-3 and FGF-4 have distinct mechanisms of action on myoepithelial cells. [less ▲]

Les migrations de remontée des poissons dans la Meuse liégeoise et l’Ourthe. Bilan des connaissances et perspectives.

Conference (1998, October 21)

Tnf-Alpha and Ifn-Gamma Down-Regulate the Expression of the Metastasis-Associated Bi-Functional 37lrp/P40 Gene and Protein in Transformed Keratinocytes

in Biochemical and Biophysical Research Communications (1998), 251(2), 564-9

The 37 LRP/p40 molecule is a bi-functional protein in which expression is increased in a large variety of cancers in association with their metastatic phenotype. Here we present the first data concerning ... [more ▼]

The 37 LRP/p40 molecule is a bi-functional protein in which expression is increased in a large variety of cancers in association with their metastatic phenotype. Here we present the first data concerning the 37 LRP/p40 gene promoter activity and show that it is very active in a cervix carcinoma cell line. Interestingly, despite hallmarks of a housekeeping gene, we show that the 37 LRP/p40 gene promoter can be down-regulated by two potentially anticancerous cytokines, TNF-alpha and IFN-gamma. In addition, the dual fate of the protein, i.e., being intracellularly involved in the cell translation machinery and incorporated into a 67-kDa cell surface protein functioning as a laminin receptor (67LR), is differentially affected by the treatment. Our data suggest multiple regulation levels in the control of the 67LR/37LRP/p40 molecule expression and uncover new clues for the understanding of both the control of expression of this metastasis-associated molecule and the IFN-gamma and TNF-alpha anticancerous action. [less ▲]