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See detailStable isotope characteristics of some infra-littoral benthic food-webs of Papuasian eastern coasts
Dauby, Patrick ULg; Nyssen, Fabienne; Lepoint, Gilles ULg et al

Poster (1998, December)

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See detailQuelle formation pour quels formateurs pour quel enseignement des langues (le cas du français langue étrangère) ?
Defays, Jean-Marc ULg

in Un enseignement moderne des langues vivantes étrangères pour des citoyens européens (1998)

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See detailPowerful alternative asymmetric catalytic dihydroxylation of olefins
Colaux, Catherine ULg; Krief, Alain

Poster (1998, December)

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See detailMise à jour de l'Atlas des chemins vicinaux
Collette, Jean-Pierre ULg; Hanocq, Philippe ULg; Zirbes, Christian

Report (1998)

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See detailJeunesse et violence à l'école: approche sociologique
Robert, Jocelyne ULg

in Education-Formation (1998), 252(hiver),

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See detailA propos des prothèses mammaires. L'examen senologique conventionnel
Lifrange, Eric ULg; Colin, Claude ULg

in Revue Médicale de Liège (1998), 53(12), 746-9

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See detailInternal functionalization in hyperbranched polyesters
Trollsas, Michaël; Hedrick, James L.; Mecerreyes, David et al

in Journal of Polymer Science. Part A, Polymer Chemistry (1998), 35(17), 3187-3192

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See detailStereocomplexation of sPMMA-PBD-sPMMA triblock copolymers with isotactic PMMA. II: Effect of molecular weight
Yu, Jian Ming; Jérôme, Robert ULg

in Polymer (1998), 39(25), 6567-6575

Thermoplastic elastomers consisting of triblock copolymers (MBM) with outer syndiotactic poly(methyl methacrylate) (sPMMA) blocks associated to an inner polybutadiene (PBD) block have been modified by ... [more ▼]

Thermoplastic elastomers consisting of triblock copolymers (MBM) with outer syndiotactic poly(methyl methacrylate) (sPMMA) blocks associated to an inner polybutadiene (PBD) block have been modified by stereocomplexation with isotactic PMMA (iPMMA) at a constant 2/1 sPMMA/iPMMA (or s/i) mixing ratio. Toluene cast films of these stereocomplexes have been studied by thermal analysis as a function of molecular weight of the sPMMA blocks and the iPMMA homopolymer. Although the melting temperature of the stereocomplex (Tm) is independent of molecular weight of the sPMMA blocks ( sPMMA) in the studied range from 7000 to 46 000, the melting enthalpy increases with increasing sPMMA. This effect is, however, erased by the sample annealing at 140°C for 15 h, and a melting enthalpy of cα. 33 J/g total PMMA is then observed whatever the copolymer composition. One melting endotherm is observed in case of low sPMMA. although two melting endotherms are reported for higher sPMMA depending, however, on the heating rate. Two endotherms are indeed observed at small sPMMA as the heating rate is low. Molecular weight of iPMMA has no significant effect on either the melting temperature or the melting enthalpy of the stereocomplexes. Dynamic mechanical analysis has confirmed the phase separation of the complexed triblock copolymers. At constant molecular weight of PBD and iPMMA, stereocomplexation increases the tensile strength of MBM copolymers containing small sPMMA blocks, whereas the opposite effect is observed for longer sPMMA blocks. When the same MBM copolymer is complexed by iPMMA, the tensile properties are independent of the molecular weight of iPMMA at least in the range from 5000 to 74 000. [less ▲]

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See detailMultimodular Penicillin-Binding Proteins: An Enigmatic Family of Orthologs and Paralogs
Goffin, Colette ULg; Ghuysen, Jean-Marie ULg

in Microbiology & Molecular Biology Reviews (1998), 62(4), 1079-1093

The monofunctional penicillin-binding DD-peptidases and penicillin-hydrolyzing serine beta-lactamases diverged from a common ancestor by the acquisition of structural changes in the polypeptide chain ... [more ▼]

The monofunctional penicillin-binding DD-peptidases and penicillin-hydrolyzing serine beta-lactamases diverged from a common ancestor by the acquisition of structural changes in the polypeptide chain while retaining the same folding, three-motif amino acid sequence signature, serine-assisted catalytic mechanism, and active-site topology. Fusion events gave rise to multimodular penicillin-binding proteins (PBPs). The acyl serine transferase penicillin-binding (PB) module possesses the three active-site defining motifs of the superfamily; it is linked to the carboxy end of a non-penicillin-binding (n-PB) module through a conserved fusion site; the two modules form a single polypeptide chain which folds on the exterior of the plasma membrane and is anchored by a transmembrane spanner; and the full-size PBPs cluster into two classes, A and B. In the class A PBPs, the n-PB modules are a continuum of diverging sequences; they possess a five-motif amino acid sequence signature, and conserved dicarboxylic amino acid residues are probably elements of the glycosyl transferase catalytic center. The PB modules fall into five subclasses: A1 and A2 in gram-negative bacteria and A3, A4, and A5 in gram-positive bacteria. The full-size class A PBPs combine the required enzymatic activities for peptidoglycan assembly from lipid-transported disaccharide-peptide units and almost certainly prescribe different, PB-module specific traits in peptidoglycan cross-linking. In the class B PBPs, the PB and n-PB modules cluster in a concerted manner. A PB module of subclass B2 or B3 is linked to an n-PB module of subclass B2 or B3 in gram-negative bacteria, and a PB module of subclass B1, B4, or B5 is linked to an n-PB module of subclass B1, B4, or B5 in gram-positive bacteria. Class B PBPs are involved in cell morphogenesis. The three motifs borne by the n-PB modules are probably sites for module-module interaction and the polypeptide stretches which extend between motifs 1 and 2 are sites for protein-protein interaction. The full-size class B PBPs are an assortment of orthologs and paralogs, which prescribe traits as complex as wall expansion and septum formation. PBPs of subclass B1 are unique to gram-positive bacteria. They are not essential, but they represent an important mechanism of resistance to penicillin among the enterococci and staphylococci. Natural evolution and PBP- and beta-lactamase-mediated resistance show that the ability of the catalytic centers to adapt their properties to new situations is limitless. Studies of the reaction pathways by using the methods of quantum chemistry suggest that resistance to penicillin is a road of no return. [less ▲]

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See detailA rapid immunochromatographic test (ICT) for serological diagnosis of tuberculosis
Hayette, Marie-Pierre ULg; Serpe, K.; Gonissen, Viviane et al

Poster (1998, November 28)

The lCT tuberculosis is an in vitro immunodiagnostic test for the detection of antibodies to Mycobacterium tuberculosis in serum or plasma. This test targets 5 recombinant M tuberculosis proteins ... [more ▼]

The lCT tuberculosis is an in vitro immunodiagnostic test for the detection of antibodies to Mycobacterium tuberculosis in serum or plasma. This test targets 5 recombinant M tuberculosis proteins, including the 38 and 85 KDa antigens. We evaluated this test on 65 sera from patients with and without TB living in Liege. Patients and methods: This test was performed on two groups : The TB group included 31 patients condidered to have an active tuberculosis : pulmonary (26 cases) or extrapulmonary (5 cases). All of them had at least one sample with positive culture and received anti-tuberculous treatment. The identification of TB strains was performed with Accuprobe M tuberculosis complexe (Gen-Probe). The second group (control group) included 34 patients with the following characteristics: BCG negative nonexposed healthy (19), BCG positive or exposed healthy (2), non-TB respiratory disease (10), atypical TB (3). The identification of the atypical mycobacteria was determined according to the biochemical characteristics or by molecular biology. Results. The sensitivity is 38.7%, the specificity is 94%. The positive predictive value is 85.7% and the negative predictive value is 62,7%. Two false lCT positive results were found in the control group: both patients had a past infection with TB. Conclusion: This test is very easy and rapid to perform, has a good specificity but lacks sensitivity in low prevalence countries. A positive lCT allows same day diagnosis of Mycobacterium tuberculosis infection. [less ▲]

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See detailExploration isocinétique du genou : importance pour la rééducation fonctionnelle
Croisier, Jean-Louis ULg

in Actes du Symposium National de Réadaptation (1998, November 28)

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See detailConditions pratiques et thérapeutiques de la césarienne dans l'espèce bovine : résultats d'une enquête franco-belge.
Hanzen, Christian ULg; Houtain, Jean Yves

in Navetat, Henri; Schelcher, François (Eds.) Le nouveau peripartum (1998, November 28)

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See detailDesign, synthesis and biological evaluation of sulfonylureas as original non-prostanoid thromboxane A2 receptor antagonists
Dogne, J. M.; De Leval, X.; Damas, J. et al

Poster (1998, November 27)

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See detailDu réel à l'imaginaire : figuration d'une lecture
Servais, Christine ULg

Conference (1998, November 27)

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See detailDesign, synthesis and biological evaluation of sulfonylureas as original non-prostanoïd thromboxane A2 receptor antagonists
Dogne, J. M.; De Leval, X.; Damas, J. et al

Conference (1998, November 27)

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See detailChemical Experts & their roles in the Belgian Sugar Industry
Melard, François ULg

Conference (1998, November 25)

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See detailPharmacological study of original 3-alkylamino-2-methyl-2H-pyrido[4,3-e]-1,2,4-thiadiazine 1,1-dioxides
Ouedraogo, R.; Nguyen, Q. A.; Antoine, M. H. et al

Poster (1998, November 21)

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See detailEstablishment of a new Tet-On cell line inducible for expression of CIPAR1 gene
Cornet, Anne ULg

Scientific conference (1998, November 21)

In prostate cancer therapy, the components of the cell death could play an important role: it is conceivable that targeted tranfer of such genes into prostatic cells could be useful. In our laboratory, a ... [more ▼]

In prostate cancer therapy, the components of the cell death could play an important role: it is conceivable that targeted tranfer of such genes into prostatic cells could be useful. In our laboratory, a new gene, the CIPAR1 (fro Castration Induced Prostatic Apoptosis Related 1), was identified by Marc Bruyninx. This gene is upregulated when the rat prostate is induced to undergo apoptosis. To learn more about the cellular function of the CIPAR1, we have decided to establish a stable cell line inducible for the expression of CIPAR1 using the "Tet-On expression system" of Clontech. Thanks to this system, we now possess a Tet-On cell line expressing CIPAR1 under Tet control. It has a high expression level of CIPAR1 and this expression can be quantitatively regulated. We hope that this stable cell line will let us elucidate the cellular functions of CIPAR1. [less ▲]

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See detailEtude de la stratégie d'autorépétition les personnes porteuses d'une trisomie 21
Frenkel, Stéphanie ULg

Conference given outside the academic context (1998)

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