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See detailPrimary non-Hodgkin's lymphoma of the nasal cavity: prognostic significance of paranasal extension and role of radiotherapy and chemotherapy
Li, Y-X; COUCKE, Philippe ULg; Li, J-Y et al

in International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society (1998), 83(3), 449-456

BACKGROUND. This study was conducted to determine whether the paranasal extension of a primary non-Hodgkin’s lymphoma (NHL) of the nasal cavity has any deleterious effect on patient outcome. METHODS. One ... [more ▼]

BACKGROUND. This study was conducted to determine whether the paranasal extension of a primary non-Hodgkin’s lymphoma (NHL) of the nasal cavity has any deleterious effect on patient outcome. METHODS. One hundred and seventy-five patients with previously untreated nasal NHL were reviewed. There were 2 with low grade, 107 with intermediate grade, 17 with high grade, and 49 with unclassifiable lymphomas. In 48 cases the immunophenotype was available and 46 were T-cell lymphoma. According to the Ann Arbor system, there were 133 patients with Stage IE, 28 with Stage IIE, 4 with Stage IIIE, and 10 with Stage IVE lymphomas. Stage IE was subdivided into limited Stage IE (i.e., confined to the nasal cavity [67 patients]) or extensive Stage IE (i.e., presenting with extension beyond the nasal cavity [66 patients]). For patients with limited Stage IE disease the treatment of choice was radiotherapy with or without chemotherapy. In patients with extensive Stage IE disease, treatment was comprised of a combination of chemotherapy and radiotherapy or radiotherapy alone. For patients with a more advanced stage of disease (IIE–IVE), chemotherapy was an integral part of the treatment and was completed by irradiation, especially for patients with Stage IIE disease. RESULTS. The actuarial overall survival (OS) and disease free survival (DFS) rates at 5 years for the whole group were 65% and 57%, respectively. The 5-year OS and DFS rates were influenced by stage, with a gradual decrease from 75% and 68% for Stage IE disease to 35% and 28% for Stage IIE disease, and 31% and 19% for Stage IIIE/IVE disease. Patients with limited Stage IE disease survived significantly longer (90% 5-year OS) compared with those with extensive Stage IE disease (57% 5-year OS; P , 0.001). For 67 patients with limited Stage IE disease, the 5-year OS was 89% with radiotherapy alone and 92% with radiotherapy and chemotherapy, whereas for 66 patients with extensive Stage IE disease, the 5-year OS was 54% with radiotherapy and 58% with combined modality therapy or chemotherapy (P . 0.05). CONCLUSIONS. The prognosis of patients with primary NHL of the nasal cavity is stage dependent. In this large cohort of Stage IE patients, it was demonstrated that the paranasal local extension was a significant prognostic factor associated with poorer treatment outcome. The authors believe that Ann Arbor Stage IE should be subclassified further into limited and extensive Stage IE. The addition of chemotherapy did not appear to modify significantly the survival of patients with either limited or extensive Stage IE disease. The extranodal progression observed in patients with extensive Stage IE and Stage IIE-IVE disease clearly illustrates the need for improvement of systemic treatment. Cancer 1998;83:449–56. [less ▲]

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See detailAssessment of respiratory mechanics with impulse oscillometry in horses with upper and lower airway obstruction
Van Erck, Emmanuelle; Duvivier, D. H.; Art, Tatiana ULg et al

in Plügers Archives European Journal of Physiology (1998)

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See detailHeavy-flavour pentaquarks in a chiral constituent quark model
Genovese, M.; Richard, J. M.; Stancu, Floarea ULg et al

in Physics Letters B (1998), B425

Within the chiral constituent quark model of Glozman and Riska, we discuss the stability of heavy pentaquarks, i.e. hadrons containing four light quarks and a heavy antiquark. The spin-dependent part of ... [more ▼]

Within the chiral constituent quark model of Glozman and Riska, we discuss the stability of heavy pentaquarks, i.e. hadrons containing four light quarks and a heavy antiquark. The spin-dependent part of the Hamiltonian is dominated by the short-range part of the Goldstone-boson-exchange interaction. We find that these systems are not bound, having an energy above the lowest dissociation threshold into a baryon and a meson. [less ▲]

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See detailL'enseignement des sciences. UN défi pour notre système éducatif
Monseur, Christian ULg; Demeuse, Marc

in Athena (1998)

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See detailMammals from the Azores islands (Portugal): an updated overview
Mathias, Maria da Luz; Ramalhinho, Maria Graça; Santos-Reis, Margarida et al

in Mammalia (1998), 62(3), 397-407

Nine species of mammals are recorded for the Azores islands: one insectivore (Erinaceus europaeus), two bats (Myotis myotis, Nyctalus azoreum), one lagomorph (Oryctolagus cuniculus), three rodents (Rattus ... [more ▼]

Nine species of mammals are recorded for the Azores islands: one insectivore (Erinaceus europaeus), two bats (Myotis myotis, Nyctalus azoreum), one lagomorph (Oryctolagus cuniculus), three rodents (Rattus norvegicus, R. rattus, Mus musculus domesticus) and two carnivores (Mustela nivalis, M. furo). Here, notes on the origin and known distribution are given for each species, together with taxonomical and ecological cmments. Except for bats all the remaining species seem to have been introduced under the influence of the man's exploratory and commercial activities [less ▲]

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See detailFinancing sources for village agents of the rice channel in the Mekong Region
Dogot, Thomas ULg; Lebailly, Philippe ULg

in BADC; Vietnam Women's Union (Eds.) Proceedings of the Workshop "Projects with a credit component in South-East Asia" (1998)

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See detailHow the *H-particle* unravels the quark dynamics
Stancu, Floarea ULg; Pepin, S.; Glozman, L Ya

in Physical Review. D : Particles and Fields (1998), D57

It is shown that the short-range part of the Goldstone boson exchange interaction between the constituent quarks, which explains baryon spectroscopy and the short-range repulsion in the NN system, induces ... [more ▼]

It is shown that the short-range part of the Goldstone boson exchange interaction between the constituent quarks, which explains baryon spectroscopy and the short-range repulsion in the NN system, induces a strong short-range repulsion in the flavour-singlet state of the $S=-2$ system with $J^P=0^+$. This suggests that a deeply bound H-particle should not exist. We compare our approach with other models employing different hyperfine interactions between quarks in the nonperturbative regime of QCD. [less ▲]

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See detailAnalysis of dentate gyrus long-term potentiation in calretinin mutant mice
Schurmans, Stéphane ULg

in Cell Biology International (1998), 22(5), 372-374

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See detailChirurgie vasculaire chez l'octogénaire
VAN DAMME, Hendrik ULg; SMITZ, Simon ULg; LARBUISSON, Robert ULg et al

in Revue Médicale de Liège (1998), 53(3), 149-57

The prevalence of peripheral vascular disease increases with aging of the population. About 8% of the octogenarians present significant carotid artery stenosis, about 4% have an abdominal aortic anneurysm ... [more ▼]

The prevalence of peripheral vascular disease increases with aging of the population. About 8% of the octogenarians present significant carotid artery stenosis, about 4% have an abdominal aortic anneurysm of 40 mm or more, and 6% suffer critical limb ischemia. Carotid endarterectomy in octogenarians is a valuable tool for stroke prevention, only if the combined perioperative stroke-mortality rate is lower than 3%. Operating an abdominal aneurysm of 50 mm or more in octogenarians is characterized by an operative mortality that is higher compared to that observed in a younger patient group (4.7% vs 2.7%). Aneurysm-surgery remains nevertheless justified, since it is the only way to prevent the evolution to rupture, that is almost fatal. Limb salvage surgery should always be considered for an 80-years patient with critical limb ischemia, since readaptation after major limb-amputation is not evident for octogenarians. An extensive review of literature is presented concerning vascular aging and results of carotid surgery, aneurysm repair and lower limb revascularization in octogenarians. The authors report their own recent experience with carotid surgery and aneurysm repair in patients aged 80 years or older. [less ▲]

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See detailHydrodynamical and ecosystem modelling on an IBM SP/2 (part II)
Elmoussaoui, A.; Grégoire, Marilaure ULg; Nomérange, P. et al

in Procedings of the third annual MMARIE meeting (1998)

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See detailBlues-Essential Album Guide (Gospel & Blues Musicians and Singers : biographical entries)
Sacré, Robert ULg

in Rucker, Leland (Ed.) Music Hound Blues - The Essential Album Guide (1998)

Notices biographiques de : The Aces, Billy Boy Arnold,, Eddie Burns, C.J. Chenier, Robert Covington, Thomas A.Dorsey, Henry Gray, Guitar Gabriel, Jessie Mae Hemphill, Eddie Lee Jones,, Lazy Lester ... [more ▼]

Notices biographiques de : The Aces, Billy Boy Arnold,, Eddie Burns, C.J. Chenier, Robert Covington, Thomas A.Dorsey, Henry Gray, Guitar Gabriel, Jessie Mae Hemphill, Eddie Lee Jones,, Lazy Lester, Lonesome Sundown, Louisiana Red, Memphis Minnie, Mississippi Heat, Rosetta Tharpe, Baby Boy Warren, Big John Wrencher, Johnny Young. [less ▲]

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See detailEffects of the interaction between habitat properties and disturbance characteristics on the interior/edge ratio.
Bogaert, Jan ULg; Verbeeck, A; Impens, I

in Farina, A (Ed.) Proceedings of the VII International Congress of Ecology (1998)

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See detailComment j'explore ... la néphropathie diabétique. Deuxième partie: suivi de la filtration glomérulaire
Weekers, Laurent ULg; Scheen, André ULg; Godon, J. P.

in Revue Médicale de Liège (1998), 53(9), 571-5

The natural history of diabetic renal disease can be divided into different stages according to the degree of albuminuria and the level of glomerular filtration rate (GFR). Assessment of the early ... [more ▼]

The natural history of diabetic renal disease can be divided into different stages according to the degree of albuminuria and the level of glomerular filtration rate (GFR). Assessment of the early hyperfiltration state, as well as determination of the rate of decline in kidney function at a later stage require precise and accurate methods to measure GFR. In this article, we briefly remind the reader of the physiological basis of GFR. We then review the different techniques for the monitoring of kidney function (inulin clearance, endogenous creatinine clearance, plasma disappearance of a radiolabelled tracer) and discuss the pro and cons of each of them in different clinical settings. Finally, we try to define a rational use of these techniques in everyday clinical practice. [less ▲]

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See detailHemovigilance: Clinical Tolerance of Solvent-Detergent Treated Plasma
Baudoux, Etienne ULg; Margraff, U.; Coenen, Alain ULg et al

in Vox Sanguinis (1998), 74(Suppl 1), 237-9

OBJECTIVE: This study was conducted to assess retrospectively the clinical tolerance of SD treated plasma and to compare it to other labile blood products (red blood cell and platelet concentrates ... [more ▼]

OBJECTIVE: This study was conducted to assess retrospectively the clinical tolerance of SD treated plasma and to compare it to other labile blood products (red blood cell and platelet concentrates). METHODS: Adverse events (AEs) related to the use of blood products at the Blood Transfusion Center (BTC) are routinely collected through a formalised system of hemovigilance. All AEs reported are entered into a safety data base which was used for the study. All AEs reported during a one-year period to the BTC were retrospectively re-assessed and descriptive statistics calculated. RESULTS: 5064 units of SD treated plasma were transfused to 894 recipients during the study period at the occasion of 1553 transfusions. No AE associated to SD treatment plasma was reported during that period. In contrast, during the same period, 485 AEs associated with the use of red blood cell concentrates (RBCC) were reported in 251 patients at the occasion of 262 transfusions. 2.1% (251/11,748) of the patients transfused with RBCC experienced one or more AEs. The incidence of AEs per unit transfused was 1.3% (485/37,332), and 2.4% (485/20,460) of RBCC transfusions were associated with one or more AEs. 142 AEs associated with the use of platelet concentrate (PC) were observed in 69 patients at the occasion of 73 transfusions. 4.2% (69/1645) of patients transfused with PC experienced one or more AEs. The incidence of AEs per unit transfused was 1.1% (142/12,772), and 2.8% (142/5034) of PC transfusions were associated with one or more AEs. All reported AEs were classified and non serious. The most frequently observed AEs were fever, chills and rashes which accounted for roughly 64% of all reported AEs. CONCLUSION: As for the overall clinical tolerance of red cell and platelet concentrates, the results of this study are in complete agreement with the published literature. The study also confirms the extremely good tolerability of SD treated plasma in comparison with other labile blood products. [less ▲]

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See detailComparaison empirique de méthodes de prédiction en régression linéaire multiple
Fonton, N. H.; Palm, Rodolphe ULg

in Revue de Statistique Appliquée (1998), XLVI(3), 53-64

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See detailThe production of pro- and anti-inflammatory cytokines in neonates assessed by stimulated whole cord blood culture and by plasma levels at birth.
SEGHAYE, Marie-Christine ULg; Heyl, W.; Grabitz, R. G. et al

in Biology of the Neonate (1998), 73(4), 220-7

The capability of neonates to achieve cytokine balance was evaluated. Production of the pro-inflammatory cytokines TNF alpha and IL-8, of the natural anti-inflammatory cytokine IL10 and of the regulator ... [more ▼]

The capability of neonates to achieve cytokine balance was evaluated. Production of the pro-inflammatory cytokines TNF alpha and IL-8, of the natural anti-inflammatory cytokine IL10 and of the regulator of the acute phase response IL6 was assessed after whole blood stimulation by lipopolysaccharide in cord blood (n = 10), adult volunteers serving as control (n = 17). Additionally, circulating cytokines were determined in cord and in maternal blood immediately after delivery (n = 27, respectively). Significant production of TNF alpha, IL8, IL10 and IL6 was observed in cord blood after lipopolysaccharide stimulation and was similar to cytokine production in adult blood. The plasma concentrations of TNF alpha were significantly higher in cord than in maternal blood, while plasma concentrations of IL10 and IL6 were significantly lower. Our results demonstrate fully developed capability of whole cord blood to synthesize pro- and anti-inflammatory cytokines in response to a pro-inflammatory stimulation in vitro. In vivo, however, higher circulating TNF alpha and lower IL10 and IL6 levels in cord blood suggest that the inflammatory stress associated with normal delivery does not induce detectable anti-inflammatory response in neonates at birth. [less ▲]

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See detailEvolution de l'agriculture wallonne au cours des vingt dernières années
Burny, Philippe ULg

in Association belge d'Economie Rurale (Ed.) Deuxième workshop pour économistes agricoles (1998)

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