Applications cliniques du soage de la troponine cardiaque: comparaison avec les marqueurs myocardiques classiques

Conference (1998, October 17)

Le traitement microchirurgical des sulcus, vergetures par dissection au Laser C02 et injection de collagène. Résultats à propos de 31 cas.

Conference (1998, October 15)

Interlocking Biological and Political Uncertainties in Public Decision Making : A Case Study at Mellery (Belgium)

Conference (1998, October 13)

A central question in health hazard associated with environmental pollution is the evaluation of level of exposure to a mixture of carcinogens and the estimation of the global health impact on the ... [more ▼]

A central question in health hazard associated with environmental pollution is the evaluation of level of exposure to a mixture of carcinogens and the estimation of the global health impact on the residents. The point is important to found a public health decision for site intervention or residents relocalisation. Belgium had to face such a problem at Mellery, a village which became internationally famous some years ago, when local residents denonced a local pollution originating from an industrial waste depository facility situated only 500 m from the centre of their village, in a former sand quarry. A central piece of the actions of the authorities was the original campaign organised to measure directly the level of exposure to carcinogens of a large group of voluntary local residents, children included, by measuring biomarkers of exposure in blood lymphocytes : for its high sensitivity, the frequency of sister chromatid exchanges (SCES) had been chosen. This biomonitoring method, quite commonly used to monitor occupational environment, had never before been applied to evaluate the potential health impact of the environment on a general population. Such data, although sophisticate and integrative, are only indicators of exposure and cannot be used, so far, as individual quantitative predictors of the possible evolution of the health of the individual persons. First designed as an epidemiological study, the campaign at Mellery revealed so high exposure levels that the experts did not keep with the original experimental line and decided to release individual information to the concerned persons, without much preparation nor risk communication policy. Several groups (experts, local doctors, local and regional authorities, public agencies and residents associations) were active integrating the information in their respective discourses, giving them specific interpretative and competing meanings. Any scenario for intervention had to be embedded in some meaningful and legitimating discourse : a quite difficult task for the authorities. The evolution of the expertise system used for public decision-making were marked by several such uncertainties (geological, biological, medical) but also by the difficult integration of health related aspects within environment interventions in the regulatory structures in Belgium : health responsibilities are scattered between federal and "communautaire" bodies, while most of the environmental actions are funded at the regional level. In this first heavy case, the young regional institutions reacted in a disorganized manner: they choose to not put at risk their frail power equilibrium and to not reconsider the attribution of the responsibilities. The authors propose to analyse how peculiar interlocking of the biological and political uncertainties were at the core of the general failure in public risk management around this landfill site: Mellery, after 10 years and a huge budget for site treatment, is still a nightmare for environmental authorities in Southern Belgium. [less ▲]

Les nouveaux marqueurs de l'infarctus du myocarde

Conference (1998, October 10)

Acromegalie : Onderzoeken

in Medical News (1998), 51

Canonical variabes of aquatic bryophyte combinations for predicting water trophic level.

in Hydrobiologia (1998), 386

Pathological Investigations on Guillemots (Uria Aalge) Stranded on the Belgian Coast During the Winter of 1993-94

in Veterinary Record : Journal of the British Veterinary Association (1998), 143(14), 387-90

Pathological investigations were carried out on 67 guillemots (Uria aalge) washed up on the Belgian coast between November 1993 and March 1994. Emaciation and acute haemorrhagic gastroenteropathy were ... [more ▼]

Pathological investigations were carried out on 67 guillemots (Uria aalge) washed up on the Belgian coast between November 1993 and March 1994. Emaciation and acute haemorrhagic gastroenteropathy were observed in more than 70 per cent of the birds. There was no statistical relationship between the level of oil contamination and the severity of the lesions. Differences in bodyweight were accounted for by age, sex, emaciation, and acute haemorrhagic gastroenteropathy. The birds had a severe weight deficit but the concentrations of pollutants were below acutely toxic levels. [less ▲]

Acromegalie : Differentiaal-diagnose

in Medical News (1998), 50

Molecular Cloning of a Mutated Hoxb7 Cdna Encoding a Truncated Transactivating Homeodomain-Containing Protein

in Journal of Cellular Biochemistry (1998), 71(1), 46-54

Homeodomain-containing proteins regulate, as transcription factors, the coordinated expression of genes involved in development, differentiation, and malignant transformation. We report here the molecular ... [more ▼]

Homeodomain-containing proteins regulate, as transcription factors, the coordinated expression of genes involved in development, differentiation, and malignant transformation. We report here the molecular cloning of a mutated HOXB7 transcript encoding a truncated homeodomain-containing protein in MCF7 cells. This is a new example of mutation affecting the coding region of a HOX gene. In addition, we detected two HOXB7 transcripts in several breast cell lines and demonstrated that both normal and mutated alleles were expressed at the RNA level in MCF7 cells as well as in a variety of breast tissues and lymphocytes, suggesting that a truncated HOXB7 protein might be expressed in vivo. Using transient co-transfection experiments, we demonstrated that both HOXB7 proteins can activate transcription from a consensus HOX binding sequence in breast cancer cells. Our results provide evidence that HOXB7 protein has transcription factor activity in vivo and that the two last amino acids do not contribute to this property. [less ▲]

Quasar polarization (Hutsemekers+ 1998)

Textual, factual or bibliographical database (1998)

Table 2 contains optical (V) polarimetric measurements for 42 optically selected QSOs including 29 broad absorption line QSOs. Table 3 contains a series of spectral indices characterizing the broad ... [more ▼]

Table 2 contains optical (V) polarimetric measurements for 42 optically selected QSOs including 29 broad absorption line QSOs. Table 3 contains a series of spectral indices characterizing the broad absorption line QSOs. (2 data files). [less ▲]