Protection du citoyen et expérimentation médicale

Report (1996)

Responses of six coniferous forest soils to increased (NH4)2SO4 inputs

Conference (1996, September)

Defining Critical N Loads for forests remains a major challenge, as our understanding of processes determining forest ecosystem responses to increased N deposition is still poor. Acidification will mainly ... [more ▼]

Defining Critical N Loads for forests remains a major challenge, as our understanding of processes determining forest ecosystem responses to increased N deposition is still poor. Acidification will mainly depend on the nitrification capacity, and coupled nitrate leaching, of the forest soil; yet factors controlling nitrification are not clearly established. As part of the CORE project (CEC), investigating nutrient dynamics in European coniferous forest soils, we studied the effects of increased (NH4)2SO4 deposition on soil solution chemistry at six sites situated across a climatic and pollution gradient. Roofed tension lysimeters were treated every two weeks with 2.88 kg N ha-1 (75 kg N ha-1 a-1) above ambient throughfall and monitored at the same interval for a total of 18 months. Responses to increased (NH4)2SO4 inputs varied from high ammonium retention, to highly increased ammonium leaching at the different sites. The important links between N cycle transformations and cation leaching were confirmed. The response of the nitrifiers to increased external ammonium supply was slow at all sites. The different responses of these six soils to increased (NH4)2SO4 deposition emphasizes that the effects of N loads have to be discussed in relation to soil N storage and nitrification capacity. [less ▲]

Aerosol therapy in the equine species

in In Proceedings: Journées Vétérinaires Suisses (1996, September)

Dynamic loads caused by lightning stroke in a conductor angle arrangement.

in Proceedings of teh 23rd ICLP (1996, September)

Lightning stroke going through condutor angle may cause dramatic failure of the conductors if mechanical loads are not taken into account in the design.The paper evaluate such effects by simulation and ... [more ▼]

Lightning stroke going through condutor angle may cause dramatic failure of the conductors if mechanical loads are not taken into account in the design.The paper evaluate such effects by simulation and make some proposal to reduce the maximum stress. [less ▲]

Short-circuit electrodynamic effects on multiconductors bundled.

in Proceedings of the 7th ESCC (1996, September)

Budle conductor during short-circuit behaves with a clash inducing large loads on structures, so called "pinch effect". This paper looks after simulations, tests and simple method to better understand the ... [more ▼]

Budle conductor during short-circuit behaves with a clash inducing large loads on structures, so called "pinch effect". This paper looks after simulations, tests and simple method to better understand the physics behind the general behaviour of bundle conductors. [less ▲]

Caractérisation métabolique cérébrale et neuropsychologique des syndromes parkinsoniens

in Revue Médicale de Liège (1996), 51(9), 566-70

S'il existe des signes neurologiques caractéristiques de la maladie de Parkinson, l'expérience clinique nous apprend que l'évolution individuelle des patients parkinsoniens est fort variable, et des ... [more ▼]

S'il existe des signes neurologiques caractéristiques de la maladie de Parkinson, l'expérience clinique nous apprend que l'évolution individuelle des patients parkinsoniens est fort variable, et des études anatomopathologioques révèlent que le diagnostic clinique d'un syndrome parkinsonien est parfois difficile à poser. Nous revoyons dans cet article les diagnostics différentiels des syndromes parkinsoniens, et nous discutons l'utilité de la neuroimagerie fonctionnelle et du bilan neuropsychologique pour essayer de mieux comprendre la présentation clinique. [less ▲]

The CD-Rom's in the Medical Library : an 8 year Follow-up Evaluation.

Poster (1996, September)

Laboratory and in situ grazing rates of freshwater rotifers and their contribution to community grazing rates

in Archiv für Hydrobiologie. Supplementband, Large rivers (1996), 13(1-4), 353-361

Acute Diverticulitis in Heart Transplant Recipients

in Transplant International (1996), 9(4), 376-9

Immunosuppressed patients are susceptible to complicated diverticulitis, but reports of this complication are scarce in heart graft recipients. To estimate the prevalence of acute diverticulitis in heart ... [more ▼]

Immunosuppressed patients are susceptible to complicated diverticulitis, but reports of this complication are scarce in heart graft recipients. To estimate the prevalence of acute diverticulitis in heart graft recipients, we retrospectively reviewed the cases of diverticulitis in a series of 143 patients who underwent orthotopic heart transplantation in a period of 10 years. Six (4%) of these developed acute diverticulitis and required colectomy. All of them were male patients and were older than 50 years. Four patients underwent urgent laparotomy and colon resection with end colostomy (Hartmann procedure). The two other patients suffered from diverticulitis without generalized peritonitis and underwent laparoscopic sigmoidectomy with direct transanal end-to-end anastomosis. The postoperative outcomes of these six patients were satisfactory. As are other immunosuppressed patients, heart graft recipients are susceptible to diverticulitis. Early surgical management may be safe in well-compensated patients. [less ▲]

Expression of Bone Sialoprotein in Primary Human Breast Cancer Is Associated with Poor Survival

in International Journal of Cancer = Journal International du Cancer (1996), 69(4), 350-3

We have recently demonstrated that bone sialoprotein (BSP), a bone-matrix protein involved in hydroxyapatite crystal formation, is ectopically expressed in human breast cancers. We explored a possible ... [more ▼]

We have recently demonstrated that bone sialoprotein (BSP), a bone-matrix protein involved in hydroxyapatite crystal formation, is ectopically expressed in human breast cancers. We explored a possible association between expression of BSP in primary breast cancer and patients' survival. We analyzed BSP expression in 454 breast-cancer patients by immunohistochemistry on archival paraffin-embedded material using an anti-BSP polyclonal antibody. BSP expression was correlated to survival, tumor size, axillary lymph-node status and first site of distant metastasis. Of the breast cancers analyzed, 89% expressed detectable amounts of BSP. We found a statistical association between expression of BSP and poor prognosis as indicated by survival curves analyzed using the log rank and the Gehan methods. BSP expression was significantly higher in breast-cancer patients with axillary lymph-node involvement. Interestingly, survival of patients with positive lymph nodes but BSP-negative tumors was significantly higher than that of patients with no lymph-node involvement but BSP-positive cancers. The frequency of bone metastases was higher in the group of patients with BSP-positive tumors (22%) than in the group with BSP-negative cancers (7%). There was a significant increase in the incidence of lung metastases in patients whose tumors were negative for BSP. Our data show that bone sialoprotein expression in breast cancer is associated with poor prognosis. BSP detection also appears to be a valuable marker with which to identify, among the lymph-node-negative patients, those who have high risk of disease progression. [less ▲]