References of "1996"
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See detailThe BFKL pomeron: Can it be detected?
Cudell, Jean-René ULg; Donnachie, A.; Landshoff, P. V.

in Nuclear Physics B (1996), 482

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See detailStabilization of human triosephosphate isomerase by improvement of the stability of individual alpha-helices in dimeric as well as monomeric forms of the protein
Mainfroid, Véronique; Mande, Shekhar C; Hol, Wim G J et al

in Biochemistry (1996), 35(13), 4110-7

Human triosephosphate isomerase (hTIM) is a dimeric enzyme of identical subunits, adopting the alpha/beta-barrel fold. In a previous work, a monomeric mutant of hTIM was engineered in which Met14 and ... [more ▼]

Human triosephosphate isomerase (hTIM) is a dimeric enzyme of identical subunits, adopting the alpha/beta-barrel fold. In a previous work, a monomeric mutant of hTIM was engineered in which Met14 and Arg98, two interface residues, were changed to glutamine. Analysis of equilibrium denaturation of this monomeric mutant, named M14Q/R98Q, revealed that its conformational stability, 2.5kcal/mol, is low as compared to the stability of dimeric hTIM (19.3 kcal/mol). The fact that this value is also lower than the conformational stabilities usually found for monomeric proteins suggests that the hTIM monomers are thermodynamically unstable. In the present work, we attempted to stabilize the M14Q/R98Q mutant by introducing stabilizing mutations in alpha-helices of the protein. Five mutations were proposed, designed to increase alpha-helix propensity by introducing alanines at solvent-exposed sites (Q179A, K193A), to introduce favorable interactions with helix dipoles (Q179D, S105D), or to reduce the conformational entropy of unfolding by introducing proline residues at the "N-cap" position of alpha-helices (A215P). Three replacements (Q179D, K193A, and A215P) were found to increase the stability of the native dimeric hTIM and the monomeric M14Q/R98Q. These results suggest that the monomeric hTIM mutant can be stabilized to a considerable extent by following well-established rules for protein stabilization. A comparison of the stabilizing effect performed by the mutations on the dimeric hTIM and the monomeric M14Q/R98Q allowed us to reinforce a model of equilibrium denaturation proposed for both proteins. [less ▲]

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See detailEffets du massage par appareil semi automatique : Etude scintigraphique et tonométrique
Crielaard, Jean-Michel ULg; Vanderthommen, Marc ULg; Dauchat, L. et al

in Kinésitherapie, les Annales (1996), 23(3), 102-105

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See detailA New Quicklook Optical Processor with Digital Input/Output
Litovchenko, Konstantin Ts.; Lemaire, Philippe; Barbier, Christian ULg

in Proceedings IGARSS'96 Symposium (1996)

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See detailEvolution des forêts - 1.2.5. Composition de la forêt et capital de production
Lecomte, Hugues; Rondeux, Jacques ULg

in Hallet, C.; Malaisse, François (Eds.) Etat de l'environnement wallon 1995 : 3. Forêt et sylviculture (1996)

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See detailContamination of European otters (Lutra lutra) by PCB congeners and organochlorinated pesticides in the wetlands of western France
Tans, Michael; Hugla, Jean Louis; Libois, Roland ULg et al

in Netherlands Journal of Zoology (1996), 46(3-4), 326-336

During the forty years, otter (Lutra lutra) populations have severely declined over much of Europe. One of the main regression factors appears to be pollution by organochlorine xenobiotics, especially ... [more ▼]

During the forty years, otter (Lutra lutra) populations have severely declined over much of Europe. One of the main regression factors appears to be pollution by organochlorine xenobiotics, especially PCBs. The present study took place in France, in the wetlands of the Atlantic border, where otter populations are considered to the stable. Muscle, pericaudal fat, and liver of 33 otters were analysed for 22 PCB congeners and organochlorine pesticides. The mean concentrations of organochlorinated pesticides in samples are relatively low (from 0 to 5.71 mg/kg lipid weight). The PCB concentrations are higher (mean in muscular tissue: 26.19 mg/kg lipid weight), but still remain low compared to similar samples from other countries. The relation between PCB concentration and physiological variables is discussed. Congener specific analysis shows an important contamination due to highly chlorinated congeners and a poor contaminatin due to low chlorinated congeners. Potential hazards due to organochlorinated compounds are also discussed. [less ▲]

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See detailL'entérotoxémie bovine: rôle de Clostridium perfringens
Daube, Georges ULg; Ginter, A; Manteca, C et al

Book published by Ministère de l'Agriculture et des Classes Moyennes (1996)

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See detailThe current situation of wild mammals in Belgium: an outline
Libois, Roland ULg

in Hystrix: the Italian Journal of Mammalogy (1996), 8(1-2), 35-41

The distrbution of the wild mammals of Belgium has been intensively stutied during the years '78-81'. It was the first time that such a work was undertaken in Belgium and could lead to a better ... [more ▼]

The distrbution of the wild mammals of Belgium has been intensively stutied during the years '78-81'. It was the first time that such a work was undertaken in Belgium and could lead to a better understanding of the current status of the different species. Conservation measures were olso proposed to the political authorities who thereafter edicted a legal protection of the most vulnerable species. Unfortunately, habitat protection is rather unachieved and the situation of the most endangered species is still getting worse. [less ▲]

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See detailUse of day resting places by the European otter (Lutra lutra) in the Marais Poitevin (France). A radiotracking study
Rosoux, René; Libois, Roland ULg

in Mathias, Maria da Luz; Santos Reis, Margarida; Amori, Giovanni (Eds.) et al European mammals. Proceedings of the European congress of Mammalogy (1996)

1. resting place situation. 2. pattern use of the resting places. 3. occupation pattern of resting place and the characteristics of th habitat

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See detailIsolation of nucleoli from ELT cells: a quick new method that preserves morphological integrity and high transcriptional activity.
Vandelaer, M.; Thiry, Marc ULg; Goessens, Guy ULg

in Experimental Cell Research (1996), 228(1), 125-31

We have developed a quick new method for isolating nucleoli which, unlike the methods in current use, preserves the nucleolar ultrastructure. Until now, the isolation process has generally been assumed to ... [more ▼]

We have developed a quick new method for isolating nucleoli which, unlike the methods in current use, preserves the nucleolar ultrastructure. Until now, the isolation process has generally been assumed to empty one of the three major compartments of the nucleolus, the fibrillar center, of its content. We have used the AgNOR staining and in vitro transcription assay to test the degree of structural and functional preservation of the isolated nucleoli. Our results demonstrate the value of our procedure as a reliable tool for biochemical and ultrastructural studies on the nucleolus. Moreover, these proprieties prompt us to investigate the rRNA synthesis, using a nonisotopic approach, within morphologically intact isolated nucleoli. Thus, we show that newly synthesized rRNA transcripts are located not only in the dense fibrillar component, but also indubitably in the fibrillar center. [less ▲]

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See detail3. Gestion - 3.2. Outils de gestion des forêts - 3.2.4. L'inventaire permanent des ressources ligneuses
Lecomte, Hugues; Rondeux, Jacques ULg

in Hallet, C.; Malaisse, François (Eds.) Etat de l'environnement wallon 1995 : 3. Forêt et sylviculture (1996)

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See detailRetour à l'expéditeur
Durand, Pascal ULg

Article for general public (1996)

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See detailIncidence d'autres facteurs extérieurs - 1.4.1. Incidence des tempêtes récentes - 1.4.1.1. Estimation des dégâts
Lecomte, Hugues; Rondeux, Jacques ULg

in Hallet, C.; Malaisse, François (Eds.) Etat de l'environnement wallon 1995 : 3. Forêt et sylviculture (1996)

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See detailThermographic facial pattern following an alpha2-adrenergic agonist injection in two horses suffering from Horner's syndrome
Ghafir, Y.; Art, Tatiana ULg; Lekeux, Pierre ULg

in Equine Veterinary Education (1996), 8(4), 192-195

The objective of the present study was to confirm this latter assumption, by measuring the facial skin temperature by infrared thermography after administration of an alpha2-adrenergic agonist to horses ... [more ▼]

The objective of the present study was to confirm this latter assumption, by measuring the facial skin temperature by infrared thermography after administration of an alpha2-adrenergic agonist to horses suffering from HS. [less ▲]

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See detailCytokine gene polymorphisms in inflammatory bowel disease.
Louis, Edouard ULg; Satsangi, J.; Roussomoustakaki, M. et al

in Gut (1996), 39(5), 705-10

BACKGROUND: Concordance rates in siblings and twins provide strong evidence that genetic susceptibility is important in the pathogenesis of inflammatory bowel disease. The number and identity of ... [more ▼]

BACKGROUND: Concordance rates in siblings and twins provide strong evidence that genetic susceptibility is important in the pathogenesis of inflammatory bowel disease. The number and identity of susceptibility genes is largely uncertain. Cytokine genes are attractive candidate loci. AIMS: To study allelic frequencies of polymorphisms of the interleukin-1 receptor antagonist (IL-1RA) gene and the tumour necrosis factor alpha gene in patients with inflammatory bowel disease. SUBJECTS: One hundred and twenty nine North European caucasoid patients with ulcerative colitis, 120 patients with Crohn's disease, and 89 healthy controls. METHODS: Genotyping was performed by polymerase chain reaction. A variable number of tandem repeats (VNTR) in the IL-1RA gene and a single base pair polymorphism in the TNF alpha gene promoter region (TNF-308) were analysed. RESULTS: No significant differences in IL-1RA VNTR allelic frequencies were noted between Crohn's disease (allele 1: 72.6%, allele 2: 24.7%, allele 3: 2.6%), ulcerative colitis (72.6%, 24.3%, 3.1%, respectively), and controls (76.9%, 20.8% and 2.3%). Some 42.4% of patients with ulcerative colitis and 43.4% patients with Crohn's disease were carriers of allele 2, compared with 34.8% healthy subjects. The TNF2 allele was modestly reduced in Crohn's disease (13.2%), compared with healthy subjects (21.3%; p = 0.04), and ulcerative colitis (21.6%). CONCLUSIONS: The associations demonstrated are modest: these polymorphisms are unlikely to be important determinants of overall disease susceptibility. [less ▲]

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See detailLa thermographie infrarouge dans l'étude de la thermorégulation chez le cheval : effets de l'entraînement
Ghafir, Y.; Art, Tatiana ULg; Lekeux, Pierre ULg

in Annales de Médecine Vétérinaire (1996), 140

Thermography records radiant thermal emissions and represents thermal patterns of a body. The aim of this article was to study the training effects on thermoregulation in exercising horses, by means of ... [more ▼]

Thermography records radiant thermal emissions and represents thermal patterns of a body. The aim of this article was to study the training effects on thermoregulation in exercising horses, by means of measurements of rectal and skin temperature. The results have shown a smaller increase of rectal temperature and a greater increase of cutaneous temperature following a training period of 6 weeks. They suggest an improvement of thermoregulation via the skin. [less ▲]

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See detailStandardisation des mesures en imagerie thermique infrarouge chez les grands animaux domestiques
Ghafir, Y.; Spruyt, P.; Art, Tatiana ULg et al

in Annales de Médecine Vétérinaire (1996), 140

Thermography studies pictures recorded from radiant thermal emissions of a body. This paper analyses several measurement conditions in order to make thermographic unit reliable, ie the effects of distance ... [more ▼]

Thermography studies pictures recorded from radiant thermal emissions of a body. This paper analyses several measurement conditions in order to make thermographic unit reliable, ie the effects of distance and position of the camera, the color, lenght and power. Moreover, the effects of the site on cutaneous temperature measurements were studied in exercising horses. It can be concluded that infrared thermography is a technical to measure skin temperature which requires a few conditions to be respected. Moreover, it is a sure, simple and fast method. The ideal site for measuring skin temperature inexercising horses is the neck because of its vascularisation. [less ▲]

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See detailBrecht, maintenant
Durand, Pascal ULg

Article for general public (1996)

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See detailA comprehensive pollen- and tephra- based chronostratigraphic model for the Late Glacial and Holocene Period in the French Massif Central.
Juvigné, E; Bastin, B; Delibrias, G et al

in Quaternary International (1996), 34-36

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See detailEvaluation du rôle préventif des oestroprogestatifs et des thérapeutiques non hormonales dans le cadre de l'ostéoporose postménopausique
Reginster, Jean-Yves ULg

in Journal de Gynécologie, Obstétrique et Biologie de la Reproduction (1996), 25(7), 677-83

Osteoporosis is a medical, social and economical problem for developed countries. Prevention remains the only realistic approach to reduce the burden related to this disorder. Primary prevention of ... [more ▼]

Osteoporosis is a medical, social and economical problem for developed countries. Prevention remains the only realistic approach to reduce the burden related to this disorder. Primary prevention of osteoporosis is based on efforts to reach a maximal peak bone mass at the end of the growth period and, subsequently, at the time of menopause. No pharmacological intervention is considered at this stage. Biologically, hormone replacement therapy induces a correction of the biochemical changes observed in markers of bone remodeling at the time of the menopause. A systematic screening of asymptomatic postmenopausal women followed by the induction of hormonal replacement therapy in high risk subjects appears to be an interesting cost/benefit strategy in terms of reasonable attribution of health resources. Nasal administration of calcitonin fully prevents the trabecular bone loss observed during the first years of menopause. Notwithstanding, the exact dose of nasal calcitonin able to prevent bone loss remains to be fully elucidated. Bisphosphonates inhibit bone resorption. Tiludronate prevents trabecular postmenopausal bone loss. The use of selectif estrogen receptor modulators is based on a possible differential action of these molecules, at the level of the estrogenic receptors, depending of the tissue considered. Several direct inhibitors of osteoclastic resorption are also under development. Their main target is either to prevent the linkage of osteoclasts to the bone matrix or to prevent the acidification of bone matrix required to induce the resorption process. [less ▲]

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