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See detailYounger age as a bad prognostic factor in patients with carcinoma of the cervix.
Delaloye, J-F; Pampallona, S; COUCKE, Philippe ULg et al

in European Journal of Obstetrics & Gynecology & Reproductive Biology (1996)

Objective: To verify the influence of age on the prognosis of cervix carcinoma. Study design: Five hundred and sixty eight patients treated for a FIGO stage IB-IVA with radical irradiation in the Centre ... [more ▼]

Objective: To verify the influence of age on the prognosis of cervix carcinoma. Study design: Five hundred and sixty eight patients treated for a FIGO stage IB-IVA with radical irradiation in the Centre Hospitalier Universitaire Vaudois of Lausanne were subdivided according to the following age categories: _<45, 46-60, 61-69 and > 70 years. Taking the 46-60 years age group as the reference, the hazard ratios (HR) of death and corresponding 95% confidence intervals (95% CI) were estimated by means of a Cox multivariate analysis. Results: The 5-year survival rates were, respectively, 57%, 67%, 60% and 45%. For the youngest women the risk of death was significantly increased (HR = 2.00, 95% CI [1.32-3.00]) and was even more accentuated in advanced stages. Conclusion: Age under 45 years is a bad prognostic factor in carcinoma of the cervix. [less ▲]

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See detailEffect of total treatment time on event-free survival in carcinoma of the cervix
Delaloye, J-F; COUCKE, Philippe ULg; Pampallona, S et al

in Gynecologic Oncology (1996), 60

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See detailIdentification of antigens recognized in the developing mouse brain by the RC2 antibody, a marker of radial glia
Leprince, Pierre ULg; Chanas-Sacre, G.; Wattiez, R. et al

in International Journal of Developmental Neuroscience (1996), 14(Sup. 1), 84

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See detailWhat about lorisk Figo Stage Ia and Ib, G1-G2 endometrial adenocarcinoma ?
Delaloye, J-F; Megalo; COUCKE, Philippe ULg et al

in Radiotherapy & Oncology (1996), 43(Supp 1), 6

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See detailPlace de la nalbuphine (Nubain) dans l'arsenal analgésique moderne
SENARD, Marc ULg; Tazarourte, K.; Darmon, P. L.

in Urgences médicales (1996), 15

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See detailEtude de la fiabilité d'un nouvel analyseur de lactate portable chez le cheval
Meynie, J.; Art, Tatiana ULg; Olaerts, J. et al

in Pratique Vétérinaire Equine (1996), 28(1), 37-40

A new portable lactate analyzer has been tested for its accuracy and reproducibility. Venous blood has been sampled on 12 horses while they were performing a treadmill exercise. A total of 134 samples ... [more ▼]

A new portable lactate analyzer has been tested for its accuracy and reproducibility. Venous blood has been sampled on 12 horses while they were performing a treadmill exercise. A total of 134 samples were obtained and analyzed either with the portable analyzer or with a reference method. The packed cell volume has been also determined for each sample. The results obtained with both methods were compared : the correlation between the two sets of data was satisfactory ((R2 = 0,86) but higher when the PCV was lower or equal to 55 % (R2 = 0,88). It was concluded that the portable analyzer is reliable for lactate determination in horses [less ▲]

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See detailEvaluation du débit sanguin au niveau du quadriceps électrostimulé et contracté volontairement
Vanderthommen, Marc ULg; BAUVIR, Philippe ULg; Depresseux, J.C. et al

in Annales de Kinésithérapie (1996), 23(1), 20-23

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See detailL'endotoxémie dans l'espèce équine. 1ère partie: étiologie et physiopathologie.
Amory, Hélène ULg

in Pratique Vétérinaire Equine (1996), 28

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See detailThe BFKL pomeron: Can it be detected?
Cudell, Jean-René ULg; Donnachie, A.; Landshoff, P. V.

in Nuclear Physics B (1996), 482

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See detailStabilization of human triosephosphate isomerase by improvement of the stability of individual alpha-helices in dimeric as well as monomeric forms of the protein
Mainfroid, Véronique; Mande, Shekhar C; Hol, Wim G J et al

in Biochemistry (1996), 35(13), 4110-7

Human triosephosphate isomerase (hTIM) is a dimeric enzyme of identical subunits, adopting the alpha/beta-barrel fold. In a previous work, a monomeric mutant of hTIM was engineered in which Met14 and ... [more ▼]

Human triosephosphate isomerase (hTIM) is a dimeric enzyme of identical subunits, adopting the alpha/beta-barrel fold. In a previous work, a monomeric mutant of hTIM was engineered in which Met14 and Arg98, two interface residues, were changed to glutamine. Analysis of equilibrium denaturation of this monomeric mutant, named M14Q/R98Q, revealed that its conformational stability, 2.5kcal/mol, is low as compared to the stability of dimeric hTIM (19.3 kcal/mol). The fact that this value is also lower than the conformational stabilities usually found for monomeric proteins suggests that the hTIM monomers are thermodynamically unstable. In the present work, we attempted to stabilize the M14Q/R98Q mutant by introducing stabilizing mutations in alpha-helices of the protein. Five mutations were proposed, designed to increase alpha-helix propensity by introducing alanines at solvent-exposed sites (Q179A, K193A), to introduce favorable interactions with helix dipoles (Q179D, S105D), or to reduce the conformational entropy of unfolding by introducing proline residues at the "N-cap" position of alpha-helices (A215P). Three replacements (Q179D, K193A, and A215P) were found to increase the stability of the native dimeric hTIM and the monomeric M14Q/R98Q. These results suggest that the monomeric hTIM mutant can be stabilized to a considerable extent by following well-established rules for protein stabilization. A comparison of the stabilizing effect performed by the mutations on the dimeric hTIM and the monomeric M14Q/R98Q allowed us to reinforce a model of equilibrium denaturation proposed for both proteins. [less ▲]

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See detailEffets du massage par appareil semi automatique : Etude scintigraphique et tonométrique
Crielaard, Jean-Michel ULg; Vanderthommen, Marc ULg; Dauchat, L. et al

in Kinésitherapie, les Annales (1996), 23(3), 102-105

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See detailA New Quicklook Optical Processor with Digital Input/Output
Litovchenko, Konstantin Ts.; Lemaire, Philippe; Barbier, Christian ULg

in Proceedings IGARSS'96 Symposium (1996)

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See detailEvolution des forêts - 1.2.5. Composition de la forêt et capital de production
Lecomte, Hugues; Rondeux, Jacques ULg

in Hallet, C.; Malaisse, François (Eds.) Etat de l'environnement wallon 1995 : 3. Forêt et sylviculture (1996)

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See detailContamination of European otters (Lutra lutra) by PCB congeners and organochlorinated pesticides in the wetlands of western France
Tans, Michael; Hugla, Jean Louis; Libois, Roland ULg et al

in Netherlands Journal of Zoology (1996), 46(3-4), 326-336

During the forty years, otter (Lutra lutra) populations have severely declined over much of Europe. One of the main regression factors appears to be pollution by organochlorine xenobiotics, especially ... [more ▼]

During the forty years, otter (Lutra lutra) populations have severely declined over much of Europe. One of the main regression factors appears to be pollution by organochlorine xenobiotics, especially PCBs. The present study took place in France, in the wetlands of the Atlantic border, where otter populations are considered to the stable. Muscle, pericaudal fat, and liver of 33 otters were analysed for 22 PCB congeners and organochlorine pesticides. The mean concentrations of organochlorinated pesticides in samples are relatively low (from 0 to 5.71 mg/kg lipid weight). The PCB concentrations are higher (mean in muscular tissue: 26.19 mg/kg lipid weight), but still remain low compared to similar samples from other countries. The relation between PCB concentration and physiological variables is discussed. Congener specific analysis shows an important contamination due to highly chlorinated congeners and a poor contaminatin due to low chlorinated congeners. Potential hazards due to organochlorinated compounds are also discussed. [less ▲]

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See detailThe current situation of wild mammals in Belgium: an outline
Libois, Roland ULg

in Hystrix: the Italian Journal of Mammalogy (1996), 8(1-2), 35-41

The distrbution of the wild mammals of Belgium has been intensively stutied during the years '78-81'. It was the first time that such a work was undertaken in Belgium and could lead to a better ... [more ▼]

The distrbution of the wild mammals of Belgium has been intensively stutied during the years '78-81'. It was the first time that such a work was undertaken in Belgium and could lead to a better understanding of the current status of the different species. Conservation measures were olso proposed to the political authorities who thereafter edicted a legal protection of the most vulnerable species. Unfortunately, habitat protection is rather unachieved and the situation of the most endangered species is still getting worse. [less ▲]

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See detailUse of day resting places by the European otter (Lutra lutra) in the Marais Poitevin (France). A radiotracking study
Rosoux, René; Libois, Roland ULg

in Mathias, Maria da Luz; Santos Reis, Margarida; Amori, Giovanni (Eds.) et al European mammals. Proceedings of the European congress of Mammalogy (1996)

1. resting place situation. 2. pattern use of the resting places. 3. occupation pattern of resting place and the characteristics of th habitat

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See detailIsolation of nucleoli from ELT cells: a quick new method that preserves morphological integrity and high transcriptional activity.
Vandelaer, M.; Thiry, Marc ULg; Goessens, Guy ULg

in Experimental Cell Research (1996), 228(1), 125-31

We have developed a quick new method for isolating nucleoli which, unlike the methods in current use, preserves the nucleolar ultrastructure. Until now, the isolation process has generally been assumed to ... [more ▼]

We have developed a quick new method for isolating nucleoli which, unlike the methods in current use, preserves the nucleolar ultrastructure. Until now, the isolation process has generally been assumed to empty one of the three major compartments of the nucleolus, the fibrillar center, of its content. We have used the AgNOR staining and in vitro transcription assay to test the degree of structural and functional preservation of the isolated nucleoli. Our results demonstrate the value of our procedure as a reliable tool for biochemical and ultrastructural studies on the nucleolus. Moreover, these proprieties prompt us to investigate the rRNA synthesis, using a nonisotopic approach, within morphologically intact isolated nucleoli. Thus, we show that newly synthesized rRNA transcripts are located not only in the dense fibrillar component, but also indubitably in the fibrillar center. [less ▲]

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See detail3. Gestion - 3.2. Outils de gestion des forêts - 3.2.4. L'inventaire permanent des ressources ligneuses
Lecomte, Hugues; Rondeux, Jacques ULg

in Hallet, C.; Malaisse, François (Eds.) Etat de l'environnement wallon 1995 : 3. Forêt et sylviculture (1996)

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