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See detailTranscription factor TFIIH and DNA endonuclease Rad2 constitute yeast nucleotide excision repair factor 3: implications for nucleotide excision repair and Cockayne syndrome
Habraken, Yvette ULg; Sung, Patrick; Prakash, Louise et al

in Proceedings of the National Academy of Sciences of the United States of America (1996), 93(20), 10718-22

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See detailStatic and dynamic epidemics on looped chains and looped trees
Vandewalle, Nicolas ULg; Ausloos, Marcel ULg

in Physical Review. E : Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics (1996), 54(4), 3499-3507

The dynamic epidemic model [N. Vandewalle and M. Ausloos, J. Phys. A 29, 309 (1996)] considers the growth of a cluster in a medium containing a fraction x of mobile "particles" that are pushed by a ... [more ▼]

The dynamic epidemic model [N. Vandewalle and M. Ausloos, J. Phys. A 29, 309 (1996)] considers the growth of a cluster in a medium containing a fraction x of mobile "particles" that are pushed by a propagation front. This model is exactly solved here on various chains and trees that contain loops following an "evolution matrix" method. The exact value for the percolation threshold x(c) and the critical exponents are calculated for static and mobile particles, respectively. Surprisingly, the mobile character of the particles affects the values of the critical exponents on chains but not on trees. Thus there is a nonuniversal behavior for dynamic epidemics even on d=1 lattices. [less ▲]

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See detailMolecular Basis of Neuronal Biorhythms and Paroxysms
Grisar, Thierry ULg; Lakaye, Bernard ULg; Thomas, Elizabeth

in Archives of Physiology & Biochemistry (1996), 104(6), 770-4

The molecular basis of the biorhythms are evoked in relation to cerebral EEG rhythms and paroxysms. Basic oscillatory phenomena have been well shown and modeled in systems such as the glycolytic pathway ... [more ▼]

The molecular basis of the biorhythms are evoked in relation to cerebral EEG rhythms and paroxysms. Basic oscillatory phenomena have been well shown and modeled in systems such as the glycolytic pathway, the oscillations of cAMP in amoebas and rhythms of the intracellular cycline during mitosis. In excitable cells the intracellular calcium and cAMP oscillations exhibit a signalling system with many advantages. Thus the question arises: to what extent can the EEG paroxysms observed in epileptic syndrome be due to disturbances in such basic molecular pathways that underlie intracellular molecular oscillations? The usefulness of the absence-rat-model and the implication the T type Ca(2+)-channel of the thalamic nuclei in the pathophysiology of this epileptic syndrome are discussed. [less ▲]

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See detailIdentification of Post-Transplant Anti-Alpha 5 (Iv) Collagen Alloantibodies in X-Linked Alport Syndrome
Dehan, Pierre ULg; Van den Heuvel, L. P.; Smeets, H. J. et al

in Nephrology Dialysis Transplantation (1996), 11(10), 1983-8

X-linked Alport syndrome (AS) is a heritable disorder which is associated with mutations in the type IV collagen alpha 5 (IV) chain gene (COL4A5) located on chromosome X. Following renal transplantation ... [more ▼]

X-linked Alport syndrome (AS) is a heritable disorder which is associated with mutations in the type IV collagen alpha 5 (IV) chain gene (COL4A5) located on chromosome X. Following renal transplantation, an average of 6% of male AS patients develop anti-GBM nephritis. We studied the specificity of the antibodies against type IV collagen in the serum of a patient with COL4A5 partial deletion. The specificity of these alloantibodies was determined against collagenase-digested GBM, as well as against recombinant non-collagenous (NC1) domains of the type IV collagen alpha 1(IV)-alpha 6(IV) chains expressed in escherichia coli. Immunoblotting and ELISA demonstrated that these antibodies bound specifically to the NC1 domain of alpha 5(IV) collagen. There was no binding to the NC1 domain of the other chains, including the Goodpasture antigen. Competitive ELISA confirmed the results obtained by ELISA and immunoblotting. This patient developed alloantibodies directed against antigens present in the grafted kidney, but absent from his Alport kidney. The pathogenesis of post-transplantation glomerulonephritis in the Alport patient studied is thus similar to that of Goodpasture syndrome, with the exception that the pathogenic antibodies are targeted to another alpha chain of type IV collagen. [less ▲]

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See detailNew trends in clinical toxicology
Charlier, Corinne ULg; Plomteux, Guy ULg

Conference (1996, October)

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See detailThe Numerical Simulations and Physical Model of Pipeline under Wave Action
Li; Lai; Chen et al

in Pacific/Asia Offshore Mechanics Symposium, PACOMS 96, Edited by ISOPE (1996, October)

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See detailDistribution of Aromatase-Immunoreactive Cells in the Forebrain of Zebra Finches (Taeniopygia Guttata): Implications for the Neural Action of Steroids and Nuclear Definition in the Avian Hypothalamus
Balthazart, Jacques ULg; Absil, Philippe ULg; Foidart, Agnès ULg et al

in Journal of Neurobiology (1996), 31(2), 129-48

Cells immunoreactive for the enzyme aromatase were localized in the forebrain of male zebra finches with the use of an immunocytochemistry procedure. Two polyclonal antibodies, one directed against human ... [more ▼]

Cells immunoreactive for the enzyme aromatase were localized in the forebrain of male zebra finches with the use of an immunocytochemistry procedure. Two polyclonal antibodies, one directed against human placental aromatase and the other directed against quail recombinant aromatase, revealed a heterogeneous distribution of the enzyme in the telencephalon, diencephalon, and mesencephalon. Staining was enhanced in some birds by the administration of the nonsteroidal aromatase inhibitor, R76713 racemic Vorozole) prior to the perfusion of the birds as previously described in Japanese quail. Large numbers of cells immunoreactive for aromatase were found in nuclei in the preoptic region and in the tuberal hypothalamus. A nucleus was identified in the preoptic region based on the high density of aromatase immunoreactive cells within its boundaries that appears to be homologous to the preoptic medial nucleus (POM) described previously in Japanese quail. In several birds alternate sections were stained for immunoreactive vasotocin, a marker of the paraventricular nucleus (PVN). This information facilitated the clear separation of the POM in zebra finches from nuclei that are adjacent to the POM in the preoptic area-hypothalamus, such as the PVN and the ventromedial nucleus of the hypothalamus. Positively staining cells were also detected widely throughout the telencephalon. Cells were discerned in the medial parts of the ventral hyperstriatum and neostriatum near the lateral ventricle and in dorsal and medial parts of the hippocampus. They were most abundant in the caudal neostriatum where they clustered in the dorsomedial neostriatum, and as a band of cells coursing along the dorsal edge of the lamina archistriatalis dorsalis. They were also present in high numbers in the ventrolateral aspect of the neostriatum and in the nucleus taeniae. None of the telencephalic vocal control nuclei had appreciable numbers of cells immunoreactive for aromatase within their boundaries, with the possible exception of a group of cells that may correspond to the medial part of the magnocellular nucleus of the neostriatum. The distribution of immunoreactive aromatase cells in the zebra finch brain is in excellent agreement with the distribution of cells expressing the mRNA for aromatase recently described in the finch telencephalon. This widespread telencephalic distribution of cells immunoreactive for aromatase has not been described in non-songbird species such as the Japanese quail, the ring dove, and the domestic fowl. [less ▲]

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See detailL'isocinétisme peut il être «excentrique» ?
Croisier, Jean-Louis ULg; Crielaard, Jean-Michel ULg

in Actes des 16èmes Journées Internationales de Médecine et de Traumatologie du Sport (1996, October)

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See detailAn Elastic-visco-plastic Damage Model: from Theory to Application
Wang, X. C.; Habraken, Anne ULg

in Journal de Physique IV (1996, October), 6

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See detailLas palabras bajo las palabras. La teoría de los anagramas de Ferdinand de Saussure
Starobinski, Jean; Varela, Lía; Willson, Patricia ULg

Book published by Editorial Gedisa (1996)

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See detailThyroïde et grossesse
Beckers, Albert ULg

Scientific conference (1996, October)

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See detailConvex Approximation Methods for Large Scale Structural Problems
Duysinx, Pierre ULg

in Proceedings of the 9th Nordic Seminar on Computational Mechanics (NSCM IX) (1996, October)

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See detailVimentin Expression in Cervical Carcinomas: Association with Invasive and Migratory Potential
Gilles, Christine ULg; Polette, M.; Piette, Jacques ULg et al

in Journal of Pathology (The) (1996), 180(2), 175-80

Vimentin is an intermediate filament protein normally expressed in mesenchymal cells, but evidence is accumulating in the literature which suggests that the aberrant expression of vimentin in epithelial ... [more ▼]

Vimentin is an intermediate filament protein normally expressed in mesenchymal cells, but evidence is accumulating in the literature which suggests that the aberrant expression of vimentin in epithelial cancer cells might be related to local invasiveness and metastatic potential. Vimentin expression has previously been associated with invasive properties in an in vitro model consisting of a set of HPV-33-transformed cervical keratinocyte cell lines. In the present study, in order to emphasize those in vitro findings, the expression of vimentin has been investigated in cervical neoplasms of different grades, using immunohistochemistry. A clear association is reported between vimentin expression and metastatic progression, since vimentin was detected in all invasive carcinomas and lymph node metastases, but not in CIN III lesions. These in vivo results are compared with present and previous data obtained in vitro on cervical keratinocyte cell lines, where vimentin expression also correlated with in vitro invasiveness. [less ▲]

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See detailUn état de l'offre bancaire de crédits aux Petites et Moyennes Entreprises en 1996
Van Caillie, Didier ULg; Denis, Sabine

Report (1996)

This report presents, discusses and higllights the main types of bank credit available for SMEs in Belgium in the mid-90's

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See detailThe numerical simulation and physical model test of pipeline under water action
Marchal, Jean ULg; Yucheng, Li; Guozhang, Lai et al

in Proceedings of the Fourth Pacific/Asia Offshore Mechanics Symposium, Pusan, Korea (1996)

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See detailObservations sur l'efficacité de la nouvelle passe à poissons sur l'Aisne à Bomal
Philippart, Jean-Claude ULg; Birtles, Cymon; Giroux, Florian et al

Article for general public (1996)

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See detailL'accompagnement d'équipes éducatives dans la mise en place de la réforme du premier degré: parcours scolaires et pratiques de différenciation
Guillaume, Marie-Elisabeth; Hindryckx, Marie-Noëlle ULg

in Informations pédagogiques (1996), 29

Synthèse d'une année de recherche-action basée sur l'accompagnement d'équipes éducatives dans la mise en place de la réforme du premier degré du secondaire : chronique d'une collaboration. Le travail ... [more ▼]

Synthèse d'une année de recherche-action basée sur l'accompagnement d'équipes éducatives dans la mise en place de la réforme du premier degré du secondaire : chronique d'une collaboration. Le travail collaboratif s'est effectué avec des équipes de professeurs de français de l'Athénée de Visé. Les axes de travail choisis furent les suivants :définir les compétences minimales qui devront être maîtrisées par les élèves au terme du premier degré de l'enseignement secondaire - concevoir et mettre au point de nouvelles pratiques pédagogiques et de nouveaux outils visant la construction des compétences choisies pour la première année du cycle - Intégrer des démarches d'évaluation diagnostique (quels savoirs, quelles compétences sont acquises), d'évaluation formative (repérage et analyse des difficultés d'apprentissage rencontrées par les élèves) et de pratiques de différenciation - Expérimenter les actions éducatives conçues - Evaluer celles-ci, analyser les paramètres qui ont présider à leur élaboration. [less ▲]

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See detailElaboration d'un plan de formation
Thirion, Paul ULg

in Groupe Formation des Utilisateurs de l'ABD; RéCoDA (Eds.) La bibliothèque au coeur du projet pédagogique : Compte rendu du colloque organisé par le groupe "Formation des utilisateurs" de l'ABD et RéCoDA (1996, October)

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See detailRegional brain activity during working memory tasks
Salmon, Eric ULg; Van der Linden, Martial ULg; Collette, Fabienne ULg et al

in Brain (1996), 119(Pt 5), 1617-1625

The first aim of our PET study was to replicate previous findings concerning the brain areas activated by a verbal working memory task. The second aim was to specify the neural basis of the central ... [more ▼]

The first aim of our PET study was to replicate previous findings concerning the brain areas activated by a verbal working memory task. The second aim was to specify the neural basis of the central executive, using a task of working memory updating. Our data confirm that the lower left supramarginal gyms and premotor area are the key regions subserving short-term verbal memory processes. They also suggest that the updating memory task is related to mid-dorsolateral prefrontal activation most probably responsible for the updating function of the central executive. An unexpected, predominantly right activation occurred in the inferior parietal region during the verbal memory updating task, which we related to a visuospatial strategy used to maintain the information in short-term memory. A third purpose was to explore the brain regions activated by a nonverbal, visual memory task, and our results confirm the importance of the superior occipital gyrus in the visual short-term memory. [less ▲]

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