References of "2004"
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See detailGeneration of transient dayside subauroral proton precipitation
Fuselier, S. A.; Gary, S. P.; Thomsen, M. F. et al

in Journal of Geophysical Research. Space Physics (2004), 109(A12),

The Imager for Magnetopause-to-Aurora Global Exploration ( IMAGE) spacecraft obtained the first global images of the proton aurora. One of the discoveries from these images was a region of proton ... [more ▼]

The Imager for Magnetopause-to-Aurora Global Exploration ( IMAGE) spacecraft obtained the first global images of the proton aurora. One of the discoveries from these images was a region of proton precipitation equatorward of the nominal auroral oval. This precipitation can be observed for similar to10 min immediately following a large solar wind pressure pulse. Various mechanisms have been proposed for producing this precipitation. This study focuses on one of the proposed mechanisms, the scattering and precipitation of protons due to interaction with electromagnetic ion cyclotron (EMIC) waves. Using data from the IMAGE spacecraft FUV and EUV imagers, in situ ring current data from the Los Alamos geosynchronous spacecraft, and in situ solar wind data from the ACE spacecraft, two features of the precipitation, the local time occurrence and limited latitudinal extent, are explained. The local time occurrence of the precipitation is correlated with the orientation of the pressure pulse front in the solar wind. The limited latitudinal extent of the emissions appears to be related to the interaction between the hot ring current protons and the cold plasmaspheric ions that gives rise to EMIC wave growth. [less ▲]

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See detailConsensus algorithms for the generation of all maximal bicliques
Alexe, Gabriela; Alexe, Sorin; Crama, Yves ULg et al

in Discrete Applied Mathematics (2004), 145(1 Sp. Iss. SI), 11-21

We describe a new algorithm for generating all maximal bicliques (i.e. complete bipartite. not necessarily induced subgraphs) of a graph. The algorithm is inspired by, and is quite similar to. the ... [more ▼]

We describe a new algorithm for generating all maximal bicliques (i.e. complete bipartite. not necessarily induced subgraphs) of a graph. The algorithm is inspired by, and is quite similar to. the consensus method used in propositional logic. We show that some variants of the algorithm are totally polynomial, and even incrementally polynomial. The total complexity of the most efficient variant of the algorithms presented here is polynomial in the input size. and only linear in the output size. Computational experiments demonstrate its high efficiency on randomly generated graphs with up to 2000 vertices and 20,000 edges. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

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See detailDevelopment of response models for optimising HPLC methods
Dewé, Walthère ULg; Marini Djang'Eing'A, Roland ULg; Chiap, Patrice ULg et al

in Chemometrics and Intelligent Laboratory Systems (2004), 74(2), 263-268

For optimizing a liquid chromatographic method, direct modeling some responses like minimum resolution is sometimes difficult to perform. By modeling the retention time at apex and the times associated to ... [more ▼]

For optimizing a liquid chromatographic method, direct modeling some responses like minimum resolution is sometimes difficult to perform. By modeling the retention time at apex and the times associated to 13.4% of the peak height, it is possible to obtain estimations of these responses using an adequate cascade of equations, these equations being the definitions of these responses. As a multi-criteria decision has to be taken in most of these optimizations, a Derringer's function can be defined for each response of interest and a overall desirability, on which the final is taken, can be derived. In addition, the chromatogram in any experimental point can be predicted. (C) 2004 Elsevier B.V. All rights reserved. [less ▲]

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See detailMCI conversion to dementia and the APOE genotype : A prediction study with FDG-PET
Mosconi, L.; Perani, D.; Sorbi, S. et al

in Neurology (2004), 63(12), 2332-2340

Objectives: To investigate whether the combination of fluoro-2-deoxy-D-glucose (FDG) PET measures with the APOE genotype would improve prediction of the conversion from mild cognitive impairment (MCI) to ... [more ▼]

Objectives: To investigate whether the combination of fluoro-2-deoxy-D-glucose (FDG) PET measures with the APOE genotype would improve prediction of the conversion from mild cognitive impairment (MCI) to Alzheimer disease ( AD). Method: After 1 year, 8 of 37 patients with MCI converted to AD (22%). Differences in baseline regional glucose metabolic rate (rCMRglc) across groups were assessed on a voxel-based basis using a two-factor analysis of variance with outcome (converters [n = 8] vs nonconverters [n = 29]) and APOE genotype (E4 carriers [E4+] [n = 16] vs noncarriers [E4-] [n = 21]) as grouping factors. Results were considered significant at p < 0.05, corrected for multiple comparisons. Results: All converters showed reduced rCMRglc in the inferior parietal cortex (IPC) as compared with the nonconverters. Hypometabolism in AD-typical regions, that is, temporoparietal and posterior cingulate cortex, was found for the E4+ as compared with the E4- patients, with the E4+/converters (n = 5) having additional rCMRglc reductions within frontal areas, such as the anterior cingulate (ACC) and inferior frontal (IFC) cortex. For the whole MCI sample, IPC rCMRglc predicted conversion to AD with 84% overall diagnostic accuracy (p = 0.003). Moreover, ACC and IFC rCMRglc improved prediction for the E4+ group, yielding 100% sensitivity, 90% specificity, and 94% accuracy (p < 0.0005), thus leading to an excellent discrimination. Conclusion: Fluoro-2-deoxy-D-glucose-PET measures may improve prediction of the conversion to Alzheimer disease, especially in combination with the APOE genotype. [less ▲]

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See detailLactone end-capped poly(ethylene oxide) as a new building block for biomaterials
Rieger, Jutta ULg; Bernaerts, Katrien V.; Du Prez, Filip E et al

in Macromolecules (2004), 37(26), 9738-9745

This paper reports on the synthesis of a novel poly(ethylene oxide) (PEO) macromonomer, which can be copolymerized with epsilon-caprolactone (epsilon-CL) by ring-opening polymerization (ROP). PEO chains ... [more ▼]

This paper reports on the synthesis of a novel poly(ethylene oxide) (PEO) macromonomer, which can be copolymerized with epsilon-caprolactone (epsilon-CL) by ring-opening polymerization (ROP). PEO chains end-capped by an epsilon-caprolactone unit (gammaPEO(.)CL) have been synthesized by living anionic ring-opening polymerization of ethylene oxide (EO) initiated by the potassium alkoxide of 1,4-dioxaspiro[4.5]decan-8-ol, followed by derivatization of the acetal into a ketone and the Baeyer-Villiger oxidation of the ketone into a lactone. The end-capping of PEO by epsilon-CL was assessed by FTIR, MALDI-TOF, and H-1 NMR spectroscopy. This type of macromonomer is a precursor of amphiphilic comblike copolymers consisting of a biodegradable hydrophobic backbone of poly-(epsilon-caprolactone) (PCL) and hydrophilic PEO grafts. Copolymerization of gammaPEO(.)CL with epsilon-CL was successfully initiated by aluminum alkoxide. [less ▲]

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See detailProcess for depositing strong adherend polymer coating onto an electrically conductive surface
Bertrand, Olivier; Jérôme, Robert ULg; Gautier, Sandrine et al

Patent (2004)

Process for depositing by electrografting a strong adherent polymer coating onto an electrically conductive surface comprising an electrochemical grafting at the surface of an active monomer for forming a ... [more ▼]

Process for depositing by electrografting a strong adherent polymer coating onto an electrically conductive surface comprising an electrochemical grafting at the surface of an active monomer for forming a primer coating P onto said surface and having as general formula: X0 (meth)acrylate wherein X is either part of a preformed polymer or is an intermediate agent for polyaddition reaction or is an anchoring group for attachment of a molecule having at least one complementary reactive group. Such process allows formation of new primer by one-step electro-grafting of a reactive polymer called macromonomer.; Such process also allows further modification of an initial electrografted polymer (called primer coating) to increase the coating thickness by the so-called grafting-from technique i.e. polymerization of a second monomer or to introduce other types of polymers(also called top coating) via covalent attachment between the primer and the top coating through the X ester group by the so called grafting onto technique. Such process also allows to graft onto the primer coating compounds like functional polymer, peptide, protein, oligonucleotide, dyes, drugs, anti-bacterian compounds. [less ▲]

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See detailDETECTION OF SPECIFIC NITRATED MARKERS
Reginster, Jean-Yves ULg; Deberg, Michelle; Henrotin, Yves ULg et al

Patent (2004)

Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to ... [more ▼]

Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein. [less ▲]

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See detailEvaluation des compétences cognitives, langagières et mnésiques des personnes trisomiques 21 ; pour une conception intégrative du retard mental
Frenkel, Stéphanie ULg

Doctoral thesis (2004)

Lying within the scope of the integrative theories of mental retardation, this research studies the processes of memorizing used by people with Down’s syndrome and more particularly, the strategy of ... [more ▼]

Lying within the scope of the integrative theories of mental retardation, this research studies the processes of memorizing used by people with Down’s syndrome and more particularly, the strategy of active rehearsal. The latter is defined as being the cumulative repetition of the verbal items to memorize. From this point of view, we undertook three research studies aiming at evaluating the impact of the modifications of the environment on the use of this strategy (in particular by means of a training program). The first two studies relate to adults and the last one, on children and teenagers. Moreover, the effect of linguistic competences in the use of this mnemonic strategy is examined. Furthermore, the study of this population raises many questions relating to the constitution of homogeneous groups and the evaluation of their developmental level (cognitive and linguistic), as well as the development of the various short-term memories. This work also presents our proposals for a solution to these three points. [less ▲]

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See detailCrp of Streptomyces Coelicolor Is the Third Transcription Factor of the Large Crp-Fnr Superfamily Able to Bind Camp
Derouaux, Adeline ULg; Dehareng, Dominique ULg; Lecocq, Elke et al

in Biochemical and Biophysical Research Communications (2004), 325(3), 983-90

The chromosomal inactivation of the unique transcription factor of Streptomyces coelicolor that displays a cyclic-nucleotide-binding domain, Crp(Sco), led to a germination-defective phenotype similar to ... [more ▼]

The chromosomal inactivation of the unique transcription factor of Streptomyces coelicolor that displays a cyclic-nucleotide-binding domain, Crp(Sco), led to a germination-defective phenotype similar to the mutant of the adenylate cyclase gene (cya) unable to produce cAMP. By means of cAMP affinity chromatography we demonstrate the specific cAMP-binding ability of Crp(Sco), which definitely demonstrate that a Cya/cAMP/Crp system is used to trigger germination in S. coelicolor. However, electromobility shift assays with the purified Crp(Sco)-cAMP complex and the CRP-like cis-acting element of its own promoter failed. Moreover, we were unable to complement an Escherichia coli crp mutant in trans with Crp(Sco). The fact that Vfr from Pseudomonas aeruginosa and GlxR from Corynebacterium glutamicum could complement such an E. coli mutant suggests that the way Crp(Sco) interacts with DNA should mechanistically differ from its most similar members. This hypothesis was further supported by homology modelling of Crp(Sco) that confirmed an unusual organisation of the DNA-binding domain compared to the situation observed in Crp(Eco). [less ▲]

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See detailUn mot d'ordre : bouger !
Henrotin, Yves ULg

Article for general public (2004)

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See detailPrevention of perinatal GBS infections: update and guidelines
MELIN, Pierrette ULg

Conference (2004, December 17)

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See detailHistoricité de la condition rurale en République populaire de Chine
Florence, Eric ULg

Scientific conference (2004, December 17)

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See detailDiscovery of non-biodegradable fossil cellulose.
Lechien, V.; Rodriguez, Ch.; Grandjean, Jean ULg et al

Poster (2004, December 17)

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