References of "Vandenput, Sandrina"
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See detailProjet PEPS Portail électronique de périodiques scientifiques : Étude de faisabilité pour la réalisation d’une plate-forme de mise en ligne de revues scientifiques en Communauté française Wallonie-Bruxelles
Baguet, Muriel; Bernard, Robert; Brouwer, Christian et al

Report (2004)

Étude commanditée à la Bibliothèque Interuniversitaire de la Communauté française de Belgique (BICfB) par la Ministre de Enseignement supérieur et de la Recherche scientifique de la Communauté française ... [more ▼]

Étude commanditée à la Bibliothèque Interuniversitaire de la Communauté française de Belgique (BICfB) par la Ministre de Enseignement supérieur et de la Recherche scientifique de la Communauté française Wallonie-Bruxelles afin d'étudier la faisabilité de la création d'une plateforme de publication Open Access des périodiques scientifiques publiés en Communauté Wallonie-Bruxelles. [less ▲]

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See detailEvidence-Based Veterinary Medicine
Pasleau, Françoise ULg; Vandenput, Sandrina ULg; Fairon, Nicolas ULg et al

Conference (2004, September 24)

At the University of Liege, the medical library recently merged with several entities including the libraries of Zoology, Botany, Psychology and Veterinary Medicine. Everywhere, the librarians are ... [more ▼]

At the University of Liege, the medical library recently merged with several entities including the libraries of Zoology, Botany, Psychology and Veterinary Medicine. Everywhere, the librarians are involved in teaching activities and users training programs are rather well developped in every field. But the comparison of the curriculum contents points to a few amazing differences. The most surprising one is the approach of Evidence-Based Medicine (EBM). The concept is well introduced in the medical community and it is a legal obligation for the medical students to be thaught in and to practice EBM. Surprisingly, the veterinarians don't seem very interested. Besides its impact on clinical practice, EBM is a good opportunity to create new habits that are valuable for continuing education and to develop critical appraisal skills. Thus, we wish to analyze the reasons that might explain why EBM seems to be left aside at the Faculty of Veterinary Medicine. Two approaches are envisionned. First, we plan to ask the Faculty itself about its position regarding the concept. Surveys and interviews will be conducted, distinguishing between the general practitionners, the researchers and the teaching staff. On the other hand, an in depth analysis will be conducted regarding the media available at the veterinary library. Are they suited to the practice of EBM? If not, which additional tools should be purchased ? At the end of the process, we expect to be able to adapt the content of the training sessions we offer to library users and possibly to improve the collaboration with the veterinary teaching staff. [less ▲]

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See detailRapport sur la numérisation et l’avenir des bibliothèques de l’Université de Liège
Bouquegneau, Jean-Marie ULg; Denooz, Joseph ULg; Gathon, Henry-Jean ULg et al

Report (2003)

Les missions confiées par le Recteur de l'Université de Liège au groupe de travail chargé de rédiger ce rapport étaient : • Organiser le mieux et le plus rapidement possible le développement du ... [more ▼]

Les missions confiées par le Recteur de l'Université de Liège au groupe de travail chargé de rédiger ce rapport étaient : • Organiser le mieux et le plus rapidement possible le développement du numérique dans les bibliothèques ; • Apporter des solutions aux problèmes d’essaimage des budgets et des ressources humaines. Pour répondre à ces objectifs, le Groupe de travail a commencé par relever les principaux jalons de l’évolution historique de l’informatisation dans les bibliothèques de l’Université. Il s’est ensuite attaché à évaluer l’état actuel de la numérisation dans le réseau des bibliothèques de l’Université par rapport aux développements numériques du secteur. Face à cet état des lieux, il présente des pistes pour accélérer et renforcer la numérisation des bibliothèques. Enfin, pour permettre la mise en œuvre de ce projet, il propose en conclusion des mesures à prendre au niveau de la réorganisation des bibliothèques en termes de locaux et de personnel. [less ▲]

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See detailThe Use of Cardboard Bedding Material as Part of an Environmental Control Regime for Heaves-affected Horses: In Vitro Assessment of Airborne Dust and Aeroallergen Concentration and In Vivo Effects on Lung Function
Kirschvink, Nathalie; Di silvestro, F.; Sbai, Ilham ULg et al

in Veterinary Journal (2002), 163

This study aimed to test whether shredded cardboard is an appropriate minimum-dust bedding material for heaves-affected horses. Results of standardized in vitro measurement of airborne dust and ... [more ▼]

This study aimed to test whether shredded cardboard is an appropriate minimum-dust bedding material for heaves-affected horses. Results of standardized in vitro measurement of airborne dust and aeroallergen concentrations of cardboard bedding were significantly lower than those of common bedding materials. Six heaves-affected horses in clinical remission after pasturing were stabled for two months on cardboard bedding and fed grass silage. Pulmonary function tests (PFT: ventilatory mechanics, arterial blood gases, airway inflammation scoring, bronchoalveolar cytology) were performed before, during and after this period and after stabling the horses in poor hygienic conditions. PFT values measured during and after the stabling period on cardboard bedding were not significantly different from those recorded after the period at pasture or from those of healthy horses, but were significantly different from those recorded in poor hygienic conditions. On basis of the in vitro and in vivo results it can be concluded that cardboard bedding, used in conjunction with low-dust forage, may be appropriate in the provision of minimum-dust management of heaves-affected horses [less ▲]

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See detailEffects of inhaled ipratropium bromide on breathing mechanics and gas exchange in exercising horses with chronic obstructive pulmonary disease
Bayly, W. M.; Duvivier, D. H.; Votion, D. et al

in Equine Veterinary Journal (2002), 34(1), 36-43

Six Warmblood horses suffering an acute exacerbation of COPD were tested to investigate whether inhalation of ipratropium bromide (IB) dry powder (2,400 microg) 30 min preexercise would improve their ... [more ▼]

Six Warmblood horses suffering an acute exacerbation of COPD were tested to investigate whether inhalation of ipratropium bromide (IB) dry powder (2,400 microg) 30 min preexercise would improve their exercise capacity. A cross-over protocol with an inert powder placebo (P) was used. Mechanics of breathing and arterial blood gases were determined before treatment, after treatment but pre-exercise, and during an incremental exercise test. Oxygen consumption (VO2) was also measured before and during exercise, and the time to fatigue recorded. Inhalation of IB reduced total pulmonary resistance (RL) and maximum intrapleural pressure changes (deltaPpl(max)) and increased dynamic compliance before exercise. The onset of exercise was associated with a marked decrease in RL in P-treated horses but not those receiving IB, so that RL during exercise was not affected by treatment. Although deltaPpl(max) was lower at 8,9 and 10 m/s with IB, there were no treatment-related changes in VO2, blood gases, time to fatigue or any other measurement of breathing mechanics. Therefore, although inhalation of IB prior to exercise may have improved deltaPpl(max), it had no apparent impact on the horses' capacity for exercise. [less ▲]

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See detailExercise-induced pulmonary perfusion redistribution in heaves
Harmegnies, N. F.; Duvivier, D. H.; Vandenput, Sandrina ULg et al

in Equine Veterinary Journal. Supplement (2002), 34(suppl), 478-484

This study aimed to compare exercise-induced pulmonary perfusion redistribution in healthy vs. 'heavey' horses using scintigraphy, a minimally invasive technique. Six healthy (A) and 5 'heavey' horses in ... [more ▼]

This study aimed to compare exercise-induced pulmonary perfusion redistribution in healthy vs. 'heavey' horses using scintigraphy, a minimally invasive technique. Six healthy (A) and 5 'heavey' horses in remission (B(I)) and during clinical signs of disease (B(II)) were investigated. Dimensions of the exercising pulmonary perfusion (QE) images were expressed in percent of the resting perfusion (QR) images. Computed QE to QR ratios (QE/QR) images enabled the definition of the region more perfused at exercise than at rest (R1). In all groups, exercise induced a major enlargement of the Q image but a larger increase of the lung height was found in 'heavey' horses. Compared to A, 'heavey' horses showed a larger R1 region with a significantly higher QE/QR. Location of R1 pointed out the dorsal lung region as a major site of pulmonary perfusion redistribution for all groups. This work demonstrated (1) the feasibility of using scintigraphy for studying exercise-induced pulmonary perfusion redistribution; (2) perfusion redistribution to the dorsal lung with exercise and (3) an intensified redistribution in 'heavey' horses, either clinically affected or not. [less ▲]

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See detailPulmonary perfusion redistribution in exercises horses
Votion, Dominique ULg; Harmegnies, N. F.; Duvivier, D. H. et al

in European Journal of Nuclear Medicine (2000), 41

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See detailAlveolar clearance in horses with chronic obstructive pulmonary disease
Votion, Dominique ULg; Vandenput, Sandrina ULg; Duvivier, D. H. et al

in American Journal of Veterinary Research (1999), 60

OBJECTIVE: To assess sensitivity of scintigraphic alveolar clearance rate as an indicator of alveolar epithelium damage in horses. ANIMALS: 5 healthy horses (group A) and 5 with chronic obstructive ... [more ▼]

OBJECTIVE: To assess sensitivity of scintigraphic alveolar clearance rate as an indicator of alveolar epithelium damage in horses. ANIMALS: 5 healthy horses (group A) and 5 with chronic obstructive pulmonary disease (COPD; group B). PROCEDURE: Horses underwent clearance rate (k [%/min]) determination. Clearance rate of group-B horses was determined after remission of the disease following 2 months at pasture (remission 1), stabling in a controlled environment (remission 2), and during crisis induced by exposure to moldy hay and straw. Methacholine challenge test was performed at each investigation period to determine nonspecific pulmonary airway hyperresponsiveness. Pulmonary function tests (PFT) also were performed, and cell populations in bronchoalveolar lavage (BAL) fluid were determined on another occasion. RESULTS: Group-B horses had significantly faster mean clearance rate during crisis (k = 4.30+/-0.95%/min), compared with that for remission 1(k = 1.98+/-0.55%/min), which did not differ from the rate in group-A horses (k = 1.95+/-0.33%/min). Despite lack of clinical signs of COPD during remission when stabled in a controlled environment, an intermediate value was found (k = 3.20+/-0.72%/min). CONCLUSIONS: This technique allowed grading of lung damage induced by COPD, whereas use of PFT and determination of BAL fluid cell populations failed to differentiate between remission 1 and remission 2. CLINICAL RELEVANCE: Determination of alveolar clearance rate by use of scintigraphy is a sensitive indicator of lung damage. A modified clearance rate was found despite the lack of clinical and functional changes [less ▲]

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See detailAnalysis of Scintigraphical Lung Images before and after Treatment of Horses Suffering from Chronic Pulmonary Disease
Votion, Dominique ULg; Ghafir, Y.; Vandenput, Sandrina ULg et al

in Veterinary Record : Journal of the British Veterinary Association (1999), 144(9), 232-236

Scintigraphical analysis of the ratio of inhalation (I) to perfusion (Q) was designed to determine whether chronic pulmonary disease in horses induced mismatches in I/Q and to assess whether medical ... [more ▼]

Scintigraphical analysis of the ratio of inhalation (I) to perfusion (Q) was designed to determine whether chronic pulmonary disease in horses induced mismatches in I/Q and to assess whether medical treatment would restore an I/Q distribution pattern identical to that of control horses. In addition, the results of the I/Q analysis were correlated with the alveolar-arterial PO2 difference (AaDO2). The I/Q matching found in a group of control horses was compared with the I/Q analysis of a group of diseased horses before and after their clinical signs had been treated. The analysis indicated that there was mismatching between I and Q before they were treated. The treatment improved the diseased horses, pulmonary function but there was still heterogeneity in the I/Q distribution after they had been treated. The I/Q analysis parameters were well correlated with the ratio of ventilation (VA) and pulmonary blood flow (Q), evaluated by the determination of AaDO2 [less ▲]

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See detailEffects of inhaled dry powderipratropium broide on reconvery from exercise of horses with COPD
Duvivier, Dominique Hannia; Bayly, Warwick M; Votion, Dominique ULg et al

in Equine Veterinary Journal (1999), 31(1), 20-24

The present study evaluated ventilatory, cardiovascular and metabolic parameters during recovery from strenuous exercise in horses suffering from a crisis of chronic obstructive pulmonary disease (COPD ... [more ▼]

The present study evaluated ventilatory, cardiovascular and metabolic parameters during recovery from strenuous exercise in horses suffering from a crisis of chronic obstructive pulmonary disease (COPD) and to determine whether ipratropium dry powder inhalation (DPI) before exercise has an effect on these parameters. When 6 saddle horses, affected with COPD, developed airway obstruction, they inhaled placebo and ipratropium (2400 pghorse), the order being randomly chosen. Pulmonary function tests were then recorded 15 min after inhalation. Following these tests, the horses underwent a strenuous treadmill exercise, followed by a ecovery period that consisted of a 10 min walk. Measurements were made at the first and tenth min of recovery. Respiratory flow, 0 2 and C02 fractions in the respired gas, pleural pressure changes and heart rate were recorded. Arterial and mixed venous blood samples were analysed or gas tensions, haemoglobin and plasma lactate concentrations. Oxygen consumption (Wz), C02 production, tidal volume, alveolar oxygen tension (PAOz), alveolar ventilation, the alveolar-pulmonary capillary oxygen difference ((A-a)dOz) and total pulmonary resistance (RL) were measured. The PA02 was the only parameter significantly improved during recovery following ipratropium DPI. This improvement was not accompanied by evidence of improvement of other ventilatory or cardiorespiratory parameters. The results showed that in horses suffering from a crisis of COPD, recovery is characterised by an exercise-induced bronchodilation. Secondly, ipratropium DPI at a dose of 2400 pghorse is an effective bronchoddator in these horses at rest but it has little effect on the airway calibre during the recovery period. It is suggested that the short term recovery period is still Muenced by exercise-induced adjustments that may exceed the bronchodilatory effect of inhaled ipratropium that are observed before exercise [less ▲]

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See detailImpact of different environmental managements on spatial distribution of ventilation in COPD horses
Vandenput, Sandrina ULg; Rollin, Frédéric ULg; Votion, Dominique ULg et al

in Plügers Archives European Journal of Physiology (1998)

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See detailDoes an Acute COPD Crisis Modify the Cardiorespiratory and Ventilatory Adjustments to Exercise in Horses?
Art, Tatiana ULg; Duvivier, Dominique Hannia; Votion, Dominique ULg et al

in Journal of Applied Physiology (Bethesda, Md. : 1985) (1998), 84(3), 845-52

The present study was conducted to understand better the mechanisms leading to the decrease in exercise capacity observed in horses suffering from chronic obstructive pulmonary disease (COPD). Five COPD ... [more ▼]

The present study was conducted to understand better the mechanisms leading to the decrease in exercise capacity observed in horses suffering from chronic obstructive pulmonary disease (COPD). Five COPD horses were submitted to a standardized submaximal treadmill exercise test while they were in clinical remission or in acute crisis. Respiratory airflow, O2 and CO2 fractions in the respired gas, pleural pressure changes and heart rate were recorded, and arterial and mixed venous blood were analyzed for gas tensions, hemoglobin, and plasma lactate concentrations. O2 consumption, CO2 production, expired minute ventilation, tidal volume, alveolar ventilation, cardiac output, total pulmonary resistance, and mechanical work of breathing were calculated. The results showed that, when submaximally exercised, COPD horses in crisis were significantly more hypoxemic and hypercapnic and that their total pulmonary resistance and mechanical work of breathing were significantly higher and their expired minute ventilation significantly lower than when they were in remission. However, their O2 consumption remained unchanged, which was probably due to the occurrence of compensatory mechanisms, i.e., higher heart rate, cardiac output, and hemoglobin concentration. Last, their net anaerobic metabolism seemed to be more important. [less ▲]

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See detailEnvironmental control to maintain stabled COPD horses in clinical remission: effects on pulmonary function
Vandenput, Sandrina ULg; Duvivier, D. H.; Votion, Dominique ULg et al

in Equine Veterinary Journal (1998), 30(2), 93-96

The objective of this study was to test the hypothesis that stabled COPD horses can be maintained in clinical remission by replacing hay by grass silage and bedding made of wood shavings (Period B) and of ... [more ▼]

The objective of this study was to test the hypothesis that stabled COPD horses can be maintained in clinical remission by replacing hay by grass silage and bedding made of wood shavings (Period B) and of wheat straw (Period C) during 6 weeks, respectively. At the end of these different periods, the pulmonary function of the horses was assessed by mechanics of breathing and arterial blood analyses. These results were compared to those measured in clinical remission obtained after 2 months in pasture (Period A). No significant difference was observed between these 3 periods neither to values obtained for healthy horses placed during 6 weeks in a hay environment. For all that, COPD horses placed in contact with hay in the same barn developed within mean +/- s.d. 8+/-3 days clinical signs of heaves and significant alterations of pulmonary function parameters. [less ▲]

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See detailScintigraphical Evaluation of Alveolar Clearance in Horses
Votion, Dominique ULg; Vandenput, Sandrina ULg; Duvivier, D. H. et al

in Veterinary Journal (1998), 156(1), 51-58

This study proposed a standardized method for measuring alveolar epithelium membrane permeability in the horse. The normal rate of clearance (%.min-1) from lung into blood of nebulized 99mTc-DTPA has been ... [more ▼]

This study proposed a standardized method for measuring alveolar epithelium membrane permeability in the horse. The normal rate of clearance (%.min-1) from lung into blood of nebulized 99mTc-DTPA has been established for healthy horses (Group A) compared with values obtained with horses suffering from chronic obstructive pulmonary disease (COPD; Group B). The 99mTc-DTPA clearance was measured in the caudoventral (R1) and in the half caudal (R2) parts of the left lung during different time intervals. The two regions aimed to define the influence of the airways on measured clearance (R2 contained proportionally more conducting airways than R1). It was concluded that a comparison of groups of subjects may be performed in R2 and on data collected during a 20 min period. The normal clearance rate in R2 was 1.80 +/- 0.46%.min-1 (T1/2R2 = 40.99 +/- 12.45 min) in Group A. In Group B, a significantly faster 99mTc-DTPA transfer rate was found (4.17 +/- 0.83%.min-1 or T1/2R2 = 17.17 +/- 3.38min). Bronchoalveolar lavage (BAL) suggested that the increased permeability measured in Group B could be the result of lung inflammatory responses. Our results have demonstrated the ability of the 99mTc-DTPA clearance test to detect alveolar epithelial damage in horses. Furthermore, we were able to show that a regional analysis of the alveolar-capillary barrier integrity may be performed satisfactorily in the equine patient. [less ▲]

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See detailEffect of a set stabled environmental control on pulmonary function and airway reactivity of COPD affected horses
Vandenput, Sandrina ULg; Votion, Dominique ULg; Duvivier, D. H. et al

in Veterinary Journal (1998), 155(2), 189-195

The aim of this study was to evaluate the respiratory function of horses affected with chronic obstructive pulmonary disease (COPD) when maintained in a barn on wood shavings and fed grass silage for a ... [more ▼]

The aim of this study was to evaluate the respiratory function of horses affected with chronic obstructive pulmonary disease (COPD) when maintained in a barn on wood shavings and fed grass silage for a period of 6 weeks. The mechanics of breathing, blood gas analysis and bronchial reactivity were examined on five horses with COPD at the end of the environment-controlled period (Period B) and the results compared with values obtained after 2 months at pasture (Period A) and after the onset of clinical signs of acute crisis (Period C). The results showed that clinical and functional parameters were similar in healthy horses and in COPD horses placed on pasture or stabled and fed grass silage. Moreover, the bronchial reactivity of COPD horses at pasture was similar to the bronchial reactivity of healthy horses. COPD horses fed grass silage however presented a bronchial reactivity intermediate between those measured after Period A and Period C which suggested they would be more susceptible to develop bronchoconstriction when in contact with inhaled irritants. [less ▲]

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See detailAirway response of horses with COPD to dry powder inhalation of ipratropium bromide
Duvivier, Dominique Hannia; Votion, Dominique ULg; Vandenput, Sandrina ULg et al

in Veterinary Journal (1997), 154(2), 149-53

To determine the effects of the dry powder inhalation (DPI) of ipratropium bromide (ipratropium) on the airways of health horses and the dose-response curve in horses suffering from chronic obstructive ... [more ▼]

To determine the effects of the dry powder inhalation (DPI) of ipratropium bromide (ipratropium) on the airways of health horses and the dose-response curve in horses suffering from chronic obstructive pulmonary disease (COPD) by means of pulmonary function tests, five healthy horses were first studied. Ipratropium (2400 micrograms ipratropium horse-1) was contained in gelatine capsules and administered using a dry powder device connected to an adapted face mask. Pulmonary function tests were recorded before inhalation and 15 and 60 min after inhalation. No modification of pulmonary function was observed. The airway response to ipratropium DPI was then determined in six horses suffering from COPD. To induce airway obstruction, the horses were bedded on straw and fed hay. When the maximal change in pleural pressure during tidal breathing exceeded 1.96 kPa, pulmonary function tests were recorded before DPI, and 15 and 60 min post-inhalation. Placebo (six capsules horse-1) or ipratropium (600, 1200 and 2400 micrograms horse-1) was administered in a randomized order to each horse using the dry powder device and the adapted face mask. Neither ipratropium nor placebo DPI affected respiratory frequency (f) or tidal volume (VT). Inhalation of 600 micrograms ipratropium horse-1 resulted in a delayed decrease of total pulmonary resistance (RL) whereas dynamic compliance (Cdyn) was improved (although not significantly) at both times of measurement when compared with values following placebo inhalation. Simultaneous decreased RL and increased Cdyn, was observed within 15 min after DPI of 1200 micrograms ipratropium horse-1 and persisted for the 1 h duration of the experiment. Doubling the dose also improved pulmonary function but not significantly more than following inhalation of 1200 micrograms ipratropium. No systemic side effects were observed in either group of horses. [less ▲]

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See detailAnalysis of Equine Scintigraphical Lung Images
Votion, Dominique ULg; Vandenput, Sandrina ULg; Duvivier, H. et al

in Veterinary Journal (1997), 153(1), 49-61

A method is proposed (1) to create inhalation to perfusion ratio (I/Q) images from equine lung scintiscans and (2) to analyse these I/Q images. This method was applied to five healthy horses in order to ... [more ▼]

A method is proposed (1) to create inhalation to perfusion ratio (I/Q) images from equine lung scintiscans and (2) to analyse these I/Q images. This method was applied to five healthy horses in order to establish reference ranges of I/Q distribution pattern. Computed I/Q images were divided in three regions based on the activity due to the inhalation (I) versus perfusion (Q) procedure. For each region a regional mismatching factor (Iri), i.e. the I/Q of the region, and an intraregional mismatching factor (Lri), which expresses the variability of pixels' I/Q within the region, were calculated. The Per(Ri) and Cen(Ri), which are the percentage of pixels in the parenchymal and in the central parts of the lung belonging to the region, were also computed. Results of this analysis showed a good match between I and Q distribution pattern. [less ▲]

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See detailPemphigus foliacé dans l'espèce équine : synthèse et description de 2 cas.
Amory, Hélène ULg; Beco, Luc; Desmecht, Daniel ULg et al

in Annales de Médecine Vétérinaire (1997), 141

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See detailTreatment of COPD horses by dry powder inhalation of ipratropium bromide
Duvivier, D. H.; Votion, Dominique ULg; Vandenput, Sandrina ULg et al

in Proceedings of the 36th British Equine Veterinary Association Congress (1997)

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See detailAlveolar clearance in COPD horses
Votion, Dominique ULg; Duvivier, D. H.; Vandenput, Sandrina ULg et al

in Proceedings of the 36th British Equine Veterinary Association Congress (1997)

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