References of "Maertens De Noordhout, Alain"
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See detailIntravenous immunoglobulins in paraneoplastic brainstem encephalitis with anti-Ri antibodies
Fumal, Arnaud ULg; Jobe, Jérôme ULg; PEPIN, Jean-Louis ULg et al

in Journal of Neurology (2006), 253(10), 1360-1361

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See detailTranscranial magnetic stimulation of the visual cortex induces somatotopically organized qualia in blind subjects
Kupers, R.; Fumal, Arnaud ULg; Maertens De Noordhout, Alain ULg et al

in Proceedings of the National Academy of Sciences of the United States of America (2006), 103(35), 13256-13260

After loss of a particular sensory channel, the deprived cortex can be activated by inputs from other sensory modalities. It is not known whether activation of the rewired cortex evokes subjective ... [more ▼]

After loss of a particular sensory channel, the deprived cortex can be activated by inputs from other sensory modalities. It is not known whether activation of the rewired cortex evokes subjective experiences characteristic of that cortex or consistent with the rerouted sensory information. In a previous study, blind subjects were trained to perform visual tasks with a tongue display unit, a sensory substitution device that translates visual displays into electrotactile tongue stimulation. This cross-modal sensory stimulation activated their visual cortices. We now extend this finding by using transcranial magnetic stimulation to examine the perceptual correlates of training-induced plastic responses. We find that blind subjects proficient with the use of the tongue display unit report somatopicaily organized tactile sensations that are referred to the tongue when transcranial magnetic stimulation is applied over the occipital cortex. No such sensations were evoked in trained, blindfolded, seeing control subjects who performed the sensory substitution task equally well. These data show that the perceptual correlate of activity in a given cortical area reflects the characteristics of its novel sensory input source. [less ▲]

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See detailInduction of long-lasting changes of visual cortex excitability by five daily sessions of repetitive transcranial magnetic stimulation (rTMS) in healthy volunteers and migraine patients
Fumal, Arnaud ULg; Coppola, G.; Bohotin, V. et al

in Cephalalgia : An International Journal of Headache (2006), 26(2), 143-149

We have shown that in healthy volunteers (HV) one session of 1 Hz repetitive transcranial magnetic stimulation (rTMS) over the visual cortex induces dishabituation of visual evoked potentials (VEPs) on ... [more ▼]

We have shown that in healthy volunteers (HV) one session of 1 Hz repetitive transcranial magnetic stimulation (rTMS) over the visual cortex induces dishabituation of visual evoked potentials (VEPs) on average for 30 min, while in migraineurs one session of 10 Hz rTMS replaces the abnormal VEP potentiation by a normal habituation for 9 min. In the present study, we investigated whether repeated rTMS sessions (1 Hz in eight HV; 10 Hz in eight migraineurs) on 5 consecutive days can modify VEPs for longer periods. In all eight HV, the 1 Hz rTMS-induced dishabituation increased in duration over consecutive sessions and persisted between several hours (n = 4) and several weeks (n = 4) after the fifth session. In six out eight migraineurs, the normalization of VEP habituation by 10 Hz rTMS lasted longer after each daily stimulation but did not exceed several hours after the last session, except in two patients, where it persisted for 2 days and 1 week. Daily rTMS can thus induce long-lasting changes in cortical excitability and VEP habituation pattern. Whether this effect may be useful in preventative migraine therapy remains to be determined. [less ▲]

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See detailEarly boost and slow consolidation in motor skill learning
Hotermans, C.; Peigneux, Philippe ULg; Maertens De Noordhout, Alain ULg et al

in Learning & Memory (Cold Spring Harbor, N.Y.) (2006), 13(5, Sep-Oct), 580-583

Motorskill learning is a dynamic process that continues covertly after training has ended and eventually leads to delayed increments in performance. Current theories Suggest that this off-line improvement ... [more ▼]

Motorskill learning is a dynamic process that continues covertly after training has ended and eventually leads to delayed increments in performance. Current theories Suggest that this off-line improvement takes time and appears only after several hours. Here we show an early transient and short-lived boost in performance, emerging as early as 5-30 min after training but no longer observed 4 h later. This early boost is predictive of the performance achieved 48 h later, Suggesting its functional relevance for memory processes. [less ▲]

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See detailValeur pronostique de la TASPM dans la SLA
WANG, François-Charles ULg; GERARD, Pascale ULg; MAERTENS DE NOORDHOUT, Alain ULg

in Neurophysiologie Clinique = Clinical Neurophysiology (2006)

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See detailDiagnosing entrapment neuropathies: probes and magnets instead of electrodes and needles?
MAERTENS DE NOORDHOUT, Alain ULg

in Clinical Neurophysiology (2006), 117(3), 484-5

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See detailDopa-responsive parkinsonism after acute subdural hematoma.
MAERTENS DE NOORDHOUT, Alain ULg; DAENEN, Frédéric ULg; Bex, Vincent

in European Journal of Neurology (2006), 13(7), 10-1

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See detailGeneral principles for clinical use of repetitive transcraniat magnetic stimulation (rTMS)
Maertens De Noordhout, Alain ULg

in Neurophysiologie Clinique = Clinical Neurophysiology (2006), 36(3, May-Jun), 97-103

Repetitive transcranial magnetic stimulation (rTMS), a non-invasive technique allowing stimulating neurons in the cerebral cortex, is able to modify durably local as well as distant neuronal activity ... [more ▼]

Repetitive transcranial magnetic stimulation (rTMS), a non-invasive technique allowing stimulating neurons in the cerebral cortex, is able to modify durably local as well as distant neuronal activity. Results obtained by stimulation of the primary motor cortex and measurements of induced muscle responses suggest that effects on cortical excitability depend on stimulation frequency and intensity, as welt as of pulse-train duration. Such data, as welt as results of animal studies have brought a physiological basis for the use of rTMS for treatment of various neurological and psychiatric disorders, and particularly depression. Nevertheless, as tong as large randomized studies have not been conducted, rTMS should not replace other existing and validated therapies. (c) 2006 Elsevier Masson SAS. All rights reserved. [less ▲]

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See detailThe syndrome of transient headache with neurological deficits and CSF lymphocytosis (HaNDL): electrophysiological findings suggesting a migrainous pathophysiology
Fumal, Arnaud ULg; Vandenheede, Michel; Coppola, Giunluca et al

in Cephalalgia : An International Journal of Headache (2005), 25(9), 754-758

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See detailHypothalamic stimulation in chronic cluster headache: a pilot study of efficacy and mode of action
SCHOENEN, Jean ULg; Di Clemente, L.; Vandenheede, Michel et al

in Brain (2005), 128(Pt 4), 940-947

We enrolled six patients suffering from refractory chronic cluster headache in a pilot trial of neurostimulation of the ipsilateral ventroposterior hypothalamus using the stereotactic coordinates ... [more ▼]

We enrolled six patients suffering from refractory chronic cluster headache in a pilot trial of neurostimulation of the ipsilateral ventroposterior hypothalamus using the stereotactic coordinates published previously. After the varying durations needed to determine optimal stimulation parameters and a mean follow-up of 14.5 months, the clinical outcome is excellent in three patients (two are pain-free; one has fewer than three attacks per month), but unsatisfactory in one patient, who only has had transient remissions. Mean voltage is 3.28 V, diplopia being the major factor limiting its increase. When the stimulator was switched off in one pain-free patient, attacks resumed after 3 months until it was turned on again. In one patient the implantation procedure had to be interrupted because of a panic attack with autonomic disturbances. Another patient died from an intracerebral haemorrhage that developed along the lead tract several hours after surgery; there were no other vascular changes on post-mortem examination. After 1 month, the hypothalamic stimulation induced resistance against the attack-triggering agent nitroglycerin and tended to increase pain thresholds at extracephalic, but not at cephalic, sites. It had no detectable effect on neurohypophyseal hormones or melatonin excretion. We conclude that hypothalamic stimulation has remarkable efficacy in most, but not all, patients with treatment-resistant chronic cluster headache. Its efficacy is not due to a simple analgesic effect or to hormonal changes. Intracerebral haemorrhage cannot be neglected in the risk evaluation of the procedure. Whether it might be more prevalent than in deep-brain stimulation for movement disorders remains to be determined. [less ▲]

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See detailPROGNOSTIC VALUE OF AMPS METHOD IN ALS PATIENTS
WANG, François-Charles ULg; GERARD, Pascale ULg; BOUQUIAUX, Olivier ULg et al

in Amyotrophic Lateral Sclerosis & Other Motor Neuron Disorders (2005)

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See detailTranscranial magnetic stimulation in migraine
Maertens De Noordhout, Alain ULg; Ambrosini, A.; Sandór, P. S. et al

in Hallett, M.; Chokroverty, S. (Eds.) Magnetic stimulation in Clinical Neurophysiology (2005)

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See detailTherapeutic application of right prefrontal low repetitive transcranial magnetic stimulation on depressed patients
Fuchs, S.; Reggers, Jean ULg; Pinto, Emmanuel ULg et al

in European Neuropsychopharmacology (2004, October), 14(Suppl. 3), 226

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See detailL'électroneuromyographie en 2004 : Mises au point
WANG, François-Charles ULg; MAERTENS DE NOORDHOUT, Alain ULg

Book published by Faculté de Médecine de Liège (H. Kulbertus) (2004)

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See detailEtiologies et exploration electrophysiologique des paralysies diaphragmatiques.
MAERTENS DE NOORDHOUT, Alain ULg

in Revue Neurologique (2004), 160(12), 1239-44

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See detailMotor cortex excitability in Alzheimer's disease and in subcortical ischemic vascular dementia.
Alagona, Giovanna; Ferri, Raffaele; Pennisi, Giovanni et al

in Neuroscience Letters (2004), 362(2), 95-8

Twenty Alzheimer's disease (AD) patients, 20 subcortical ischemic vascular dementia (SIVD) patients and 20 neurologically and cognitively normal subjects underwent transcranial magnetic stimulation to ... [more ▼]

Twenty Alzheimer's disease (AD) patients, 20 subcortical ischemic vascular dementia (SIVD) patients and 20 neurologically and cognitively normal subjects underwent transcranial magnetic stimulation to study motor cortex excitability changes. Motor threshold (MT), amplitude of motor evoked potentials, silent period and the H/M ratio (amplitude of maximal Hoffman reflex vs. that of maximal motor response) were considered. MT was lower in SIVD patients when compared with AD patients (P = 0.003) and the control group (P < 0.001) and lower in AD patients when compared with the control group (P < 0.001). The increment of motor cortex excitability in AD and SIVD did not lead us to distinguish clearly the two types of dementia. It is likely that the electrophysiological similarity between AD and SIVD could represent another common mechanism shared from these forms of dementia. [less ▲]

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See detailApplications cliniques de la stimulation magnetique transcranienne repetitive.
MAERTENS DE NOORDHOUT, Alain ULg

in Revue Médicale de Liège (2004), 59 Suppl 1

Transcranial magnetic stimulation (TMS), when delivered in trains of pulses is able to induce long-lasting changes of excitability of neuronal networks, not only in the vicinity of the stimulating coil ... [more ▼]

Transcranial magnetic stimulation (TMS), when delivered in trains of pulses is able to induce long-lasting changes of excitability of neuronal networks, not only in the vicinity of the stimulating coil, but also at distant sites. Results of stimulation experiments over the motor cortex indicate that the effects (excitatory or inhibitory) depend on the frequency of stimulation. These data have prompted researchers to use repetitive transcranial magnetic stimulation (rTMS) as a therapeutic tool in various brain disorders, most notably depression. However, as long as large randomized trials have not been conducted, rTMS cannot be recommended as an alternative to validated conventional therapies of such disorders. [less ▲]

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