L'etat de stress post-traumatique chez les brules: une revue.; Hansenne, Michel ; Pitchot, William et alin Acta Psychiatrica Belgica (1993), 93 Spec No While post-traumatic stress disorder has drawn increasing interest over the last years, very few studies have been focused to burned patients. In its first part, this article provides a brief reminder of ... [more ▼] While post-traumatic stress disorder has drawn increasing interest over the last years, very few studies have been focused to burned patients. In its first part, this article provides a brief reminder of the symptomatology of post-traumatic stress disorder, of its various pathogenic theories as well as its various treatment approaches. The second part of the article reviews more specifically the literature about post-traumatic stress disorder in burned patients, emphasizing the need of a rapid and effective psychological therapy. [less ▲] Detailed reference viewed: 107 (2 ULg) Role du systeme dopaminergique dans la depression: correlats cliniques du test a l'apomorphine.Pitchot, William ; ; Hansenne, Michel et alin Acta Psychiatrica Belgica (1993), 93 Spec No Disturbances in dopaminergic neurotransmission seem to play an important role in biochemical mechanisms involved in depressive disorders. The study of the growth hormone (GH) response to apomorphine, a ... [more ▼] Disturbances in dopaminergic neurotransmission seem to play an important role in biochemical mechanisms involved in depressive disorders. The study of the growth hormone (GH) response to apomorphine, a dopaminergic agonist, provides an indirect index of dopaminergic neurotransmission at the postsynaptic level. In the present study, we assessed the role of the dopaminergic system in some psychopathological dimensions in depression: personality dimensions, suicidal behavior, psychomotor disturbances and dichotomy unipolar/bipolar. Our studies included major depressed inpatients matched for gender, age and, in the case of women, menopausal status. Our results show that dopaminergic disturbances are related to social introversion and anxiety according to dopaminergic hypothesis of schizophrenic disorders and dopaminergic hyperactivity hypothesis of anxiety disorders. A blunted GH response to apomorphine could be considered as a biological marker of suicidal behavior. Moreover motor retardation appeared to be in relationship with dopaminergic disturbances. Finally, the dopaminergic system did not appear to play a significant role in the dichotomy unipolar/bipolar. The results show the interest of the apomorphine test in the assessment of the relationship between biochemical disturbances and clinical correlates. [less ▲] Detailed reference viewed: 35 (1 ULg) Dexamethasone suppression test and prediction of treatment response to selective antidepressantsANSSEAU, Marc ; PAPART, Patrick ; PITCHOT, William et alin European Psychiatry (1992) Detailed reference viewed: 4 (0 ULg) Growth hormone response to clonidine in male untreated panic patients; ANSSEAU, Marc ; et alin Psychological Medicine (1992) Detailed reference viewed: 4 (0 ULg) Therapeutic window for 5-HT reuptake inhibitorsPITCHOT, William ; ; ANSSEAU, Marc ![]() in Lancet (1992) Detailed reference viewed: 2 (1 ULg) Suicidal behavior and growth hormone response to apomorphine test.Pitchot, William ; Hansenne, Michel ; et alin Biological Psychiatry (1992), 31(12), 1213-9 Several cerebrospinal fluid (CSF) studies have provided support for a possible role for the dopaminergic system as a biological correlate of suicidal behavior. Indeed, low CSF levels of the dopamine ... [more ▼] Several cerebrospinal fluid (CSF) studies have provided support for a possible role for the dopaminergic system as a biological correlate of suicidal behavior. Indeed, low CSF levels of the dopamine metabolite homovanillic acid (HVA) have been described in depressed patients with a history of suicide attempts. In this study, we assessed the dopamine receptor sensitivity in relationship to suicidal behavior by measuring growth hormone (GH) response to apomorphine 0.5 mg subcutaneously (sc) in 15 DSM-III-R (APA 1987) major depressive inpatients with a history of suicide attempts, compared to age-matched and gender-matched major depressive inpatients without a history of suicide. Patients with a history of suicidal behavior exhibited a significantly lower GH response to apomorphine than patients who never attempted suicide (t = 3.60, df = 1.28, p = 0.0012). Therefore, these results suggest that a blunted GH response to apomorphine could represent a biological marker of suicidal behavior. [less ▲] Detailed reference viewed: 3 (0 ULg) Dopaminergic function in panic disorder: comparison with major and minor depression.Pitchot, William ; Ansseau, Marc ; et alin Biological Psychiatry (1992), 32(11), 1004-11 Several lines of evidence suggest that dopamine might be involved in anxiety states. In this study, we assessed the growth hormone (GH) response to apomorphine (a dopaminergic agonist) 0.5 mg SC in nine ... [more ▼] Several lines of evidence suggest that dopamine might be involved in anxiety states. In this study, we assessed the growth hormone (GH) response to apomorphine (a dopaminergic agonist) 0.5 mg SC in nine drug-free inpatients meeting Research Diagnostic Criteria (RDC) for panic disorder who were age-matched and gender-matched with nine major depressive, and nine minor depressive inpatients. The three groups differed significantly in their mean GH peak response: 5.29 +/- 2.75 ng/ml in major depressives, 26.27 +/- 12.71 ng/ml in minor depressives, and 37.28 +/- 10.58 ng/ml in panics, with a significantly higher response in panic than in either minor or major depressive patients. These results support dopaminergic overactivity in panic disorder as compared with major and minor depression. [less ▲] Detailed reference viewed: 20 (0 ULg) Psychotic reactions to zolpidem.Ansseau, Marc ; Pitchot, William ; Hansenne, Michel et alin Lancet (1992), 339(8796), 809 Detailed reference viewed: 23 (1 ULg) The lack of relationship between DST nonsuppression in the dexamethasone suppression test and EEG abnormalities.Pitchot, William ; Hansenne, Michel ; Ansseau, Marc ![]() in European Archives of Psychiatry & Clinical Neuroscience (1991), 241(3), 193-4 As a recent study suggested a relationship between cortisol escape following dexamethasone suppression test (DST) and electroencephalogram (EEG) abnormalities, we tried to replicate these findings in 52 ... [more ▼] As a recent study suggested a relationship between cortisol escape following dexamethasone suppression test (DST) and electroencephalogram (EEG) abnormalities, we tried to replicate these findings in 52 major depressive inpatients. A total of 23 patients exhibited DST nonsuppression (44%) and 18 patients had EEG abnormalities (35%). No relationship existed between DST and EEG results. [less ▲] Detailed reference viewed: 18 (2 ULg) The clonidine test in posttraumatic stress disorder.Hansenne, Michel ; Pitchot, William ; Ansseau, Marc ![]() in American Journal of Psychiatry (The) (1991), 148(6), 810-1 Detailed reference viewed: 17 (2 ULg) Psychopathological correlates of dopaminergic disturbances in major depression.Pitchot, William ; Hansenne, Michel ; et alin Neuropsychobiology (1990), 24(4), 169-72 In a recent report, we confirmed the role of dopamine in the pathophysiology of depression by demonstrating a blunted response of growth hormone (GH) to apomorphine, a selective dopaminergic agonist, in ... [more ▼] In a recent report, we confirmed the role of dopamine in the pathophysiology of depression by demonstrating a blunted response of growth hormone (GH) to apomorphine, a selective dopaminergic agonist, in endogenous depressive patients. Few data are available on the possible psychopathological correlates of disturbances in the apomorphine test. In this study, we assessed the relationship between GH response to apomorphine and the Minnesota multiphasic personality inventory (MMPI) scales in a sample of 20 major depressive inpatients. The GH response (area under the curve) after apomorphine injection was positively correlated with the social introversion scale scores (r = 0.56, df = 19, p less than 0.01) and the anxiety scale scores (r = 0.45, df = 19, p = 0.04). These results suggest dopaminergic overactivity in anxious psychopathology rather than in depressive psychopathology. The relationship between the social introversion scale score and the apomorphine test is in agreement with the dopaminergic hypothesis of schizophrenic disorders. [less ▲] Detailed reference viewed: 10 (2 ULg) Contingent negative variation in psychopharmacology; Ansseau, Marc ; et alin Brunia, C. H. M.; Mulder, G.; Verbater, M. N. (Eds.) Event related potentials in brain research (1990) Detailed reference viewed: 11 (1 ULg) Hyponatrémie induite par la carbamazépine et affection rénale : à propos d'un casPITCHOT, William ; ANSSEAU, Marc ; PAPART, Patrick et alin Psychiatrie et psychobiologie (1989) Detailed reference viewed: 17 (3 ULg) Blunted response of growth hormone to clonidine and apomorphine in endogenous depressionAnsseau, Marc ; ; et alin British Journal of Psychiatry (1988), 153 Detailed reference viewed: 5 (2 ULg) Inhibitory influence of oxytocin infusion on contingent negative variation and some memory tasks in normal menGeenen, Vincent ; ; et alin Psychoneuroendocrinology (1988), 13 Detailed reference viewed: 11 (1 ULg) Neuroendocrine evaluation of catecholaminergic neurotransmission in maniaAnsseau, Marc ; ; et alin Psychiatry Research (1987), 22 Detailed reference viewed: 4 (1 ULg) Diagnostic performance of basal free cortisol/18-hydroxy-11-deoxy-corticosterone (18-OH-DOC) ratio in endogenous depression: comparison with the dexamethasone suppression test; Ansseau, Marc ; et alin Biological Psychiatry (1987), 22 Detailed reference viewed: 11 (1 ULg) Intranasal oxytocin in obsessive-compulsive disorderAnsseau, Marc ; Legros, Jean-Jacques ; Mormont, Christian et alin Psychoneuroendocrinology (1987), 12 Detailed reference viewed: 22 (5 ULg) Le point actuel sur l'utilisation de la vasopressine et de l'ocytocine en psychiatrieLegros, Jean-Jacques ; Geenen, Vincent ; Ansseau, Marc ![]() in Médecine et Hygiène (1987), 45 Detailed reference viewed: 21 (1 ULg) Dexamethasone suppression test and MMPI scalesAnsseau, Marc ; Geenen, Vincent ; et alin Neuropsychobiology (1986), 16 Detailed reference viewed: 5 (0 ULg) |
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