Validity of the French hip and knee replacement expectations surveysNEUPREZ, Audrey ; François, Garance ; et alin Osteoporosis International (2013, April), 24(Suppl.1), 374 Detailed reference viewed: 7 (3 ULg) (111)Indium-oxine labelling for evaluating the homing process of autologous osteoblasts implanted percutaneously in atrophic nonunion fractures.; Bernard, Claire ; et alin International Orthopaedics (2013), 37(1), 131-6 PURPOSE: The aim of the study was to control the in vivo localisation of implanted cells in cell-based therapies. Labelling cells with (111)indium-oxine is one of the most interesting methods proposed. We ... [more ▼] PURPOSE: The aim of the study was to control the in vivo localisation of implanted cells in cell-based therapies. Labelling cells with (111)indium-oxine is one of the most interesting methods proposed. We evaluated this method in the setting of autologous osteoblast implantation in nonunion fractures. METHODS: An in vitro study of osteoblasts was conducted after (111)indium-oxine labelling. Radioactivity retention and viability, proliferation and the ability to produce alkaline phosphatase were evaluated in a seven-day culture. In vivo labelling of implanted osteoblastic cells was conducted during a therapeutic trial of atrophic nonunion fractures, with the leakage outside the nonunion site and local uptake evolution at four, 24 and 48 hour being studied. RESULTS: The mean labelling efficiency for osteoprogenitors was 78.8 +/- 4.6 %. The intracellular retention was 89.4 +/- 2.1 % at three hours and 67.3 +/- 4.7 % at 18 hours. The viability assessed at three hours was 93.7 +/- 0.6 %. After seven days of culture, morphology and alkaline phosphatase staining were similar for both labelled and unlabelled control cells, although the proliferation rate was decreased in the labelled cells. Some local intraosseous leakage was observed in four of 17 cases. All patients showed uptake at the injection site, with four having no other uptake. Four patients showed additional uptake in the bladder, liver and spleen, while 11 patients had additional uptake in the lungs in addition to the bladder, liver and spleen. The activity ratios (injection site/body) were 48 +/- 28 % at four hours, 40 +/- 25 % at 24 hours and 35 +/- 25 % at 48 hours. After correcting for decay, the activity within the injection site was 82 +/- 15 % at 24 hours and 69 +/- 11 % at 48 hours compared with the activity measured at four hours. No relationship was found between uptake and radiological bone repair. CONCLUSIONS: The (111)indium-oxine labelling appears to be a good method for monitoring the behaviour of the osteoblastic cells after their implantation in atrophic nonunion fractures. [less ▲] Detailed reference viewed: 9 (7 ULg) Health-related quality of life after total knee or hip replacement for osteoarthritis: a 7-year prospective studyBruyère, Olivier ; Ethgen, Olivier ; Neuprez, Audrey et alin Archives of Orthopaedic & Trauma Surgery (2012) Objective To assess health-related quality of life (HRQOL) in a prospective study with 7 years of follow-up in 49 consecutive patients who underwent a total joint replacement because of osteoarthritis ... [more ▼] Objective To assess health-related quality of life (HRQOL) in a prospective study with 7 years of follow-up in 49 consecutive patients who underwent a total joint replacement because of osteoarthritis. Methods Generic HRQOL was assessed with the shortform 36 (SF-36) and specific HRQOL with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Results Out of the 39 subjects who have completed the 7 years of follow-up of this study, 22 (56.4 %) underwent a hip replacement surgery and the other 17 (43.6 %) a knee replacement. Six months after surgery, a significant improvement, compared to preoperative scores, was observed in two of the eight dimensions of the SF-36 (i.e. physical function and pain). The same dimensions, pain and physical function, at the same time, 6 months after surgery, measured by the WOMAC, showed a significant improvement as well, but there was no significant change in the stiffness score. From 6 months to the end of followup, changes in SF-36 scores showed a significant improvement in physical function (p = 0.008), role-physical (p = 0.004) and role-emotional (p = 0.01) while all scores of the WOMAC improved (p\0.001 for pain, p\0.001 for stiffness and p\0.01 for physical function). Conclusion The improvements observed in HRQOL at short term after surgery, are at least maintained over a 7-year follow-up period. [less ▲] Detailed reference viewed: 28 (13 ULg) Radiological and clinical profil of osteoarthritic patients undergoing of total joint replacementNeuprez, Audrey ; François, Garance ; Bruyère, Olivier et alin Annals of the Rheumatic Diseases (2012, June), 71(Suppl.3), 693 Detailed reference viewed: 26 (9 ULg) Assessment of quality of life in patients undergoing total joint replacement for OA of the lower limbNeuprez, Audrey ; François, Garance ; Bruyère, Olivier et alin Annals of the Rheumatic Diseases (2012, June), 71(Suppl.3), 693 Detailed reference viewed: 32 (8 ULg) Radiological and clinical profil of osteoarthritic patients undergoing of total joint replacementNeuprez, Audrey ; François, Garance ; Bruyère, Olivier et alin Osteoporosis International (2012, March), 23(Suppl. 2), 129-130 Detailed reference viewed: 24 (8 ULg) Comparison of gaseous cryotherapy with more traditional forms of cryotherapy following total knee arthroplastyDemoulin, Christophe ; ; et alin Annals of Physical and Rehabilitation Medicine (2012), 55 Detailed reference viewed: 43 (8 ULg) Comparaison de la cryothérapie gazeuse à des formes de cryothérapie plus traditionnelles après arthroplastie totale du genouDemoulin, Christophe ; ; et alin Annales de Réadaptation et de Médecine Physique (2012), 55 Detailed reference viewed: 34 (5 ULg) Evolution récente de l'incidence des fractures de hanche et de la consommation de médicaments anti-ostéoporotiques en BelgiqueHiligsmann, Mickaël ; Bruyère, Olivier ; et alin Revue du Rhumatisme (2011, December), 78(Suppl. 5), 43-44 Detailed reference viewed: 20 (6 ULg) Le rôle de l'IRM préopératoire systématique avant arthrodèse du rachis lombaire dans la prévention du syndrome néo-charnière; GILLET, Philippe ; GEORIS, Pierre ![]() in Revue Médicale de Liège (2011), 66(10), 529-534 Detailed reference viewed: 28 (9 ULg) Mécanisme et imagerie des fractures de la chevilleMEUNIER, Benoît ; JOSKIN, Julien ; GILLET, Philippe et alin Revue Médicale de Liège (2011), 66(9), 491-497 Detailed reference viewed: 41 (6 ULg) Le laboratoire d’Anatomie : un banc d’essai des nouvelles technologiesBonnet, Pierre ; Carlier, Alain ; Radermecker, Marc et alin Revue Médicale de Liège (2010), 65(Synthèse 2010), 35-40 Detailed reference viewed: 77 (23 ULg) Migration and wear of the Duraloc "1200 series" cup associated with Enduron UHWMPE using the EBRA method and the Imagika softwareThirion, Thierry ; Georis, Pierre ; Gillet, Philippe ![]() in Hip International (2010), 20(2), 198-203 Detailed reference viewed: 46 (15 ULg) Intérêt du suivi radiologique des prothèses totales de hancheThirion, Thierry ; Georis, Pierre ; Gillet, Philippe ![]() in Revue Médicale de Liège (2010), 64(2), 93-97 Detailed reference viewed: 25 (4 ULg) Le cas clinique du mois. Une cause inhabituelle de sciatalgie nécessitant un traitement chirurgical : le kyste arthrosynovial lombaireLommers, Emilie ; Gillet, Philippe ![]() in Revue Médicale de Liège (2010), 65(12), 665-8 We describe the case of a 46-year-old woman suffering from an hyperalgic sciatica caused by a lumbar synovial cyst. These are uncommon lesions associated with degenerative spine disease. They may be ... [more ▼] We describe the case of a 46-year-old woman suffering from an hyperalgic sciatica caused by a lumbar synovial cyst. These are uncommon lesions associated with degenerative spine disease. They may be asymptomatic or may produce symptoms resulting from nervous structures compression. They are commonly found at the L4-L5 level, the site of maximum mobility. Their etiopathogeny is still unclear but degenerative spinal instability is the strongest factor for their growth. MRI is the most effective for the diagnosis. Conservative management is usually unsuccessful. Resection with or without fusion remains the more appropriate therapeutic option. [less ▲] Detailed reference viewed: 21 (3 ULg) Repérage scintigraphique préopératoire d'une métastase costale unique d'un adénocarcinome prostatique opéré.Sanjurjo, Sylvia ; ; et alin Progrès en Urologie (2008), 18(6), 402-5 We present a case of a lonely bone lesion after a prostatic adenocarcinoma with recurrent increased PSA. The localization of the metastasis at the level of a rib is infrequent. The precise localization of ... [more ▼] We present a case of a lonely bone lesion after a prostatic adenocarcinoma with recurrent increased PSA. The localization of the metastasis at the level of a rib is infrequent. The precise localization of the lesion was made possible by intraoperative scintigraphy. Histology confirmed the complete resection of the lesion with safe margins. [less ▲] Detailed reference viewed: 92 (11 ULg) Biofilms endodontiques et infections tardives des prothèses totales de hancheGoffart, Joseph ; Gillet, Philippe ![]() in Revue Médicale de Liège (2007), 62(12), 736-42 Biofilms are well recognised in different settings. Endodontic biofilms containing bacteria responsible for bacteraemia and secondary infection of total hip arthroplasties (THA) represent a diagnostic ... [more ▼] Biofilms are well recognised in different settings. Endodontic biofilms containing bacteria responsible for bacteraemia and secondary infection of total hip arthroplasties (THA) represent a diagnostic challenge because they are often asymptomatic. Their treatment is difficult and inadequate management of such unrecognised sources of systemic infection can lead to the devastating situation of an infected arthroplasty necessitating implant removal, long term antibiotic treatment and secondary implantation of a new prosthesis. Since about ten percent of secondary infected THA can have a dental origin, this article is intended to give guidelines to all intervening care providers: general practitioner, orthopaedic surgeon and dentist. [less ▲] Detailed reference viewed: 77 (2 ULg) Actualités dans le traitement des pseudarthroses aseptiquesVan Cauwenberge, Henry ; Hauzeur, Jean-Philippe ; Gillet, Philippe ![]() in Revue Médicale de Liège (2007), 62(5-6), 344-351 Detailed reference viewed: 34 (4 ULg) Comment on: Long term actuarial survivorship analysis of an interspinous stabilization system (J Senegas et al.)Gillet, Philippe ![]() in European Spine Journal (2007), 16(8), 1289-1290 Detailed reference viewed: 15 (1 ULg) Actualités thérapeutiques en chirurgie orthopédique : évolution des arthroplastiesGillet, Philippe ![]() in Revue Médicale de Liège (2007), 62(5-6), 335-343 Detailed reference viewed: 22 (4 ULg) |
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