References of "Gabriel, Sabine"
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See detailCathodic electrografting of acrylics: From fundamentals to functional coatings
Gabriel, Sabine ULg; Jérôme, Robert ULg; Jérôme, Christine ULg

in Progress in Polymer Science (2010), 35

Promoting permanent adhesion between so dissimilar materials as polymers and metals is a very challenging target and a severe brake to the implementation of many potential applications. However, synthetic ... [more ▼]

Promoting permanent adhesion between so dissimilar materials as polymers and metals is a very challenging target and a severe brake to the implementation of many potential applications. However, synthetic polymers can now be chemisorbed onto a variety of conducting surfaces by cathodic electrografting of acrylic monomers. The first part of this review will focus on the fundamental aspects of this emerging technology, thus from the historical discovery to experimental and theoretical developments, with the purpose to better comprehend the electrografting phenomenon. Once firmly established, this concept has been exploited in order to make polymeric coatings with specific functionality chemisorbed onto more diversified substrates in more convenient liquid media. This remarkable progress that largely relies on advanced controlled polymerization processes will be the topic of the second part of the review, with a special emphasis on the more recent development of smart coatings, particularly stimuli responsive coatings very well-suited to nanotechnologies. [less ▲]

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See detailA generic chemical platform for molecular recognition and stimuli-responsive probes based on scanning probe microscopy
Cecchet, Francesca; Lussis, Perrine ULg; Jérôme, Christine ULg et al

in Small : Nano Micro (2008), 4(8), 1101-1104

The grafting of poly-N-succinimidyl acrylate from scanning probe microscopy tips is shown to be a robust platform for the very easy elaboration of versatile probes with sensor capabilities and tunable ... [more ▼]

The grafting of poly-N-succinimidyl acrylate from scanning probe microscopy tips is shown to be a robust platform for the very easy elaboration of versatile probes with sensor capabilities and tunable properties. The modified tips can be easily postfunctionalized for single-molecule recognition of host-guest and ligand-receptor systems and for the design of smart probes that are thermo- and pH-responsive. [less ▲]

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See detailCombination of electrografting and layer-by-layer deposition: an efficient way to tailor polymer coatings of (semi)-conductors
Charlot, Aurélia; Gabriel, Sabine ULg; Detrembleur, Christophe ULg et al

in Chemical Communications (2007), (44), 4656-4658

This communication reports on a novel, simple and highly versatile concept, which consists in combining the advantages of two complementary and relevant techniques (i) electrografting and (ii) layer-by ... [more ▼]

This communication reports on a novel, simple and highly versatile concept, which consists in combining the advantages of two complementary and relevant techniques (i) electrografting and (ii) layer-by-layer deposition process with the goal to tailor strongly adhering coatings to (semi)-conducting surfaces imparting them with tunable specific properties. [less ▲]

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See detailAtomic force microscopy investigation of the morphology and the biological activity of protein-modified surfaces for bio- and immunosensors
Cecchet, Francesca; Duwez, Anne-Sophie ULg; Gabriel, Sabine ULg et al

in Analytical Chemistry (2007), 79(17), 6488-6495

With the purpose of developing biosensors, the reliable proof of the biological activity of two new sensor systems was obtained by atomic force microscopy (AFM) in both the imaging and the single-molecule ... [more ▼]

With the purpose of developing biosensors, the reliable proof of the biological activity of two new sensor systems was obtained by atomic force microscopy (AFM) in both the imaging and the single-molecule force spectroscopy modes. Antigens or antibodies of pharmacological interest were grafted onto self-assembled monolayers of thiols on gold, and AFM imaging demonstrated that the grafting process produced homogeneous submonolayers of isolated proteins. The analysis of the morphology of the surfaces at the different functionalization steps allowed evaluating the protein grafting density and showed that the recognition of complementary species present in the surrounding solution occurred. Single-molecule force spectroscopy experiments between the sensing surfaces and AFM probes, onto which the complementary species were grafted, enabled a direct and rapid test of the biological activity of the sensors by investigating the interaction occurring at the level of one single ligand-receptor bond. Ellipsometry and surface plasmon resonance allowed further characterization of the sensor surfaces and confirmed that the biological recognition took place. [less ▲]

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See detailOne-step polymer grafting from silicon nitride SPM probes: From isolated chains to brush regime
Gabriel, Sabine ULg; Jérôme, Christine ULg; Jérôme, Robert ULg et al

in Journal of the American Chemical Society (2007), 129(27), 8410

We show that a reactive polymer can be directly grafted from commercial Si3Nx SPM tips, without any intermediate layer. The conditions can be chosen to achieve either an isolated mushroom regime, with ... [more ▼]

We show that a reactive polymer can be directly grafted from commercial Si3Nx SPM tips, without any intermediate layer. The conditions can be chosen to achieve either an isolated mushroom regime, with only one or a few chains accessible at the tip apex, or a brush regime. [less ▲]

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See detailDesign of smart SPM probes by electrografting
Gabriel, Sabine ULg; Jérôme, Christine ULg; Duwez, Anne-Sophie ULg

Conference (2007, May 11)

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See detailSynthesis of adherent hydrophilic polypyrrole coatings onto (semi)conducting surfaces
Gabriel, Sabine ULg; Cecius, Michaël ULg; Fleury-Frenette, Karl ULg et al

in Chemistry of Materials (2007), 19(9), 2364-2371

Hydrophilic and adherent polypyrrole coatings were prepared by a two-step electrochemical method. First, alpha-pyrrole, omega-acrylate polyethylene oxide (Py-PEO-A) dual macromonomer was synthesized by ... [more ▼]

Hydrophilic and adherent polypyrrole coatings were prepared by a two-step electrochemical method. First, alpha-pyrrole, omega-acrylate polyethylene oxide (Py-PEO-A) dual macromonomer was synthesized by anionic polymerization and electrografted onto (semi)conducting substrates by cathodic polymerization of the acrylic end-group. The obtained adherent coating is hydrophilic and thus swells in water and bears a pyrrole ring, a precursor of the conducting polymer. In a second step, the coating is anodically polarized in a mixture of Py and Py-PEO to give the hydrophilic and adherent polypyrrole. Properties such as morphology, adherence, electroactivity, and hydrophilicity of these coatings were investigated by conventional methods and compared to those of pure polypyrrole coatings. These novel coatings exhibit efficient protein adsorption repellency and are thus good candidates for applications in biomaterials and biosensors. [less ▲]

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See detailThermoresponsive coatings strongly adhering to (semi)conducting surfaces
Gabriel, Sabine ULg; Duwez, Anne-Sophie ULg; Jérôme, Robert ULg et al

in Langmuir (2007), 23(1), 159-161

Thermoresponsive brushes have been efficiently grafted onto (semi)conductive surfaces by a two-step process. In the first step, poly(N-succinimidyl acrylate) chains have been chemisorbed onto silicon or ... [more ▼]

Thermoresponsive brushes have been efficiently grafted onto (semi)conductive surfaces by a two-step process. In the first step, poly(N-succinimidyl acrylate) chains have been chemisorbed onto silicon or stainless steel by the electrografting method. Then, these modified electrodes were immersed in isopropylamine in order to transform the grafted chains to the thermoresponsive poly(N-isopropyl acrylamide). The thermal response of these brushes has been shown by AFM. This straightforward grafting process is quite attractive for surface modification in confined media and is thus promising for microfludics application. [less ▲]

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See detailElectrografting of thermo-responsive polymer film on conductive substrate
Gabriel, Sabine ULg; Stach, M.; Zhang, T. et al

Poster (2006, May 18)

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See detailA generic platform for SPM-based molecular recognition processes and stiluli-responsive probes
Gabriel, Sabine ULg; Jérôme, Christine ULg; Silva-Goncalves, Elsa et al

Poster (2006, May 18)

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See detailElectrografting of thin polymer films: Three strategies for the tailoring of functional adherent coatings
Voccia, Samuel; Gabriel, Sabine ULg; Serwas, Harry et al

in Progress in Organic Coatings (2006), 55(2), 175-181

Cathodic electrografting is an efficient technique to impart adhesion to poly(meth)acrylate coatings onto inorganic conducting surfaces. Although this technique was restricted for many years to very few ... [more ▼]

Cathodic electrografting is an efficient technique to impart adhesion to poly(meth)acrylate coatings onto inorganic conducting surfaces. Although this technique was restricted for many years to very few monomers ((meth)acrylonitrile and (meth)acrylates) and to deposition of very thin polymer films, recent developments have overcome these limitations. First of all, classical controlled/living polymerization techniques have been combined with cathodic electrografting as a powerful strategy for tuning thickness, properties and reactivity of the chemisorbed organic films. Secondly, thanks to the successful electrografting of a new reactive monomer bearing an activated ester, electrografted surfaces are now available for further derivatization by a wide variety of nucleophiles. Finally, the electrografting process has been extended to the direct electrografting of reactive polymers, i.e. preformed polymers beating pendant acrylic functions, which opens the way to the grafting of, e.g., polycondensates. [less ▲]

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See detailFirst insights into electrografted polymers by AFM-based force spectroscopy
Cuenot, Stéphane; Gabriel, Sabine ULg; Jérôme, Robert ULg et al

in Macromolecules (2006), 39(24), 8428-8433

The very first characterization of the structural properties of polymer films obtained by electrografting is reported. AFM-based force spectroscopy was used to investigate poly-N-succinimidyl acrylate ... [more ▼]

The very first characterization of the structural properties of polymer films obtained by electrografting is reported. AFM-based force spectroscopy was used to investigate poly-N-succinimidyl acrylate (PNSA) layers electrografted directly from a silicon substrate. Quantitative analysis of compression profiles obtained in a good solvent and single molecule bridging interaction, in light of the Alexander-de Gennes model, gave access to the grafting density and degree of polymerization. A high swelling capacity has been evidenced. This report is the first evidence that polymers obtained by cathodic electrografting are in fact brush systems, and consequently the first evidence that a polymer brush can be obtained from a direct "grafting from" method, without any intermediate layer. [less ▲]

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See detailMechanochemistry: targeted delivery of single molecules
Duwez, Anne-Sophie ULg; Cuenot, Stéphane; Jérôme, Christine ULg et al

in Nature Nanotechnology (2006), 1

The use of scanning probe microscopy-based techniques to manipulate single molecules(1) and deliver them in a precisely controlled manner to a specific target represents a significant nanotechnological ... [more ▼]

The use of scanning probe microscopy-based techniques to manipulate single molecules(1) and deliver them in a precisely controlled manner to a specific target represents a significant nanotechnological challenge(2,3). The ultimate physical limit in the design and fabrication of organic surfaces can be reached using this approach. Here we show that the atomic force microscope (AFM), which has been used extensively to investigate the stretching of individual molecules(4-12), can deliver and immobilize single molecules, one at a time, on a surface. Reactive polymer molecules, attached at one end to an AFM tip, are brought into contact with a modified silicon substrate to which they become linked by a chemical reaction. When the AFM tip is pulled away from the surface, the resulting mechanical force causes the weakest bond - the one between the tip and polymer - to break. This process transfers the polymer molecule to the substrate where it can be modified by further chemical reactions. [less ▲]

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See detailMechanochemistry: targeted delivery of single molecules
Duwez, Anne-Sophie ULg; Cuenot, Stéphane; Jérôme, Christine ULg et al

in Nature Nanotechnology (2006), 1

The use of scanning probe microscopy-based techniques to manipulate single molecules1 and deliver them in a precisely controlled manner to a specific target represents a significant nanotechnological ... [more ▼]

The use of scanning probe microscopy-based techniques to manipulate single molecules1 and deliver them in a precisely controlled manner to a specific target represents a significant nanotechnological challenge. The ultimate physical limit in the design and fabrication of organic surfaces can be reached using this approach. Here we show that the atomic force microscope (AFM), which has been used extensively to investigate the stretching of individual molecules, can deliver and immobilize single molecules, one at a time, on a surface. Reactive polymer molecules, attached at one end to an AFM tip, are brought into contact with a modified silicon substrate to which they become linked by a chemical reaction. When the AFM tip is pulled away from the surface, the resulting mechanical force causes the weakest bond — the one between the tip and polymer — to break. This process transfers the polymer molecule to the substrate where it can be modified by further chemical reactions [less ▲]

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See detailElectrografting of Poly(ethylene glycol) Acrylate : A One-Step Strategy for the Synthesis of Protein-Repellent Surfaces
Gabriel, Sabine ULg; Dubruel, Peter; Schacht, Etienne et al

in Angewandte Chemie (International ed. in English) (2005), 44(34), 5505-5509

Electrografting of acrylate end-capped poly(ethylene glycol) (PEG) is an important technique for the one-step coating of electroconductive substrates by an adherent hydrophilic coating (see figure). This ... [more ▼]

Electrografting of acrylate end-capped poly(ethylene glycol) (PEG) is an important technique for the one-step coating of electroconductive substrates by an adherent hydrophilic coating (see figure). This technique is very efficient for the production of new protein-repellent surfaces. [less ▲]

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See detailAre electrografted polymers chemisorbed or physisorbed onto their substrate ?
Cuenot, Stéphane; Gabriel, Sabine ULg; Jérôme, Christine ULg et al

in Macromolecular Chemistry and Physics (2005), 206(12), 1216-1220

AFM-based single-molecule force spectroscopy was used to evaluate the mechanical strength of the link between a polymer and the substrate onto which the polymer is electrografted. Poly(N-succinimidyl ... [more ▼]

AFM-based single-molecule force spectroscopy was used to evaluate the mechanical strength of the link between a polymer and the substrate onto which the polymer is electrografted. Poly(N-succinimidyl acrylate) was electrografted onto gold substrates and brought into contact with an aminothiol-functionalized AFM tip. Bridging of single polymer chains resulting from the strong coupling between the activated esters on the polymer and amine groups on the tip was investigated. We found that the link between the polymer and the gold substrate can withstand a force far beyond the force characteristic for physisorption on gold. [less ▲]

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See detailElectrografting of poly(ethylene glycol) acrylate: a novel one-step strategy for protein repellent surfaces
Gabriel, Sabine ULg; Dubruel, P.; Schacht, Etienne et al

Conference (2005, June 01)

Detailed reference viewed: 14 (4 ULg)