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See detailMethacholine bronchoprovocation test:a useful ancillary test for diagnosis of hyperresponsiveness in horses ?
Frippiat, Thibault ULg; Frellstedt, Linda ULg; Bustin, Jean-Clément ULg et al

in Proceedings of the European Veterinary Conference - Voorjaarsdagen (2012)

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See detailLes tests de bronchoprovocation à la métacholine dans le diagnostic de l'hyperréactivité bronchique chez le cheval asymptomatique
Frippiat, Thibault ULg; Frellstedt, Linda ULg; Bustin, Jean-Clément ULg et al

in Proceedings de la 38ème Journée de la Recherche Equine (2012)

The clinical examination and the ancillary tests at the disposal from the veterinarian may be poor diagnostics in horses suffering from subclinical inflammatory airway disease or in clinical remission of ... [more ▼]

The clinical examination and the ancillary tests at the disposal from the veterinarian may be poor diagnostics in horses suffering from subclinical inflammatory airway disease or in clinical remission of recurrent airway obstruction (RAO). The objective of this study was to determine whether the methacholine bronchoprovocation test -which is daily used for diagnosis of asymptomatic human asthma- may be used as an applicable and repeatable method for the diagnosis of an increased susceptibility to bronchospasm in horses. The test, realised on 8 horses (6 with RAO history and 2 controls) presents a good feasibility and significant repeatability. Dust exposure increased the bronchoreactivity, while it did not affect other clinical and functional parameters or inflammatory markers. In the future, the bronchoprovocation test could therefore find its place in clinicat practice for the detection of asymptomatic horses which are susceptible to develop bronchospasm in poor environmental conditions. [less ▲]

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