References of "Barriat, Sébastien"
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See detailAudiometric results after stapedotomy operations in patients with otosclerosis and preoperative small air-bone gaps
SALMON, Caroline ULg; BARRIAT, Sébastien ULg; DEMANEZ, Laurent CH P ULg et al

in Audiology & Neuro-otology (in press)

Objectives: The efficacy of stapedotomies performed on patients with small air-bone gaps (<25 dB, sABG) was compared to the efficacy of the operation in patients who had otosclerosis with high air-bone ... [more ▼]

Objectives: The efficacy of stapedotomies performed on patients with small air-bone gaps (<25 dB, sABG) was compared to the efficacy of the operation in patients who had otosclerosis with high air-bone gaps (≥25 dB, hABG). Methods: This retrospective study evaluates the short-term postoperative air and bone conduction thresholds and air-bone gaps after 181 CO2 laser stapedotomies. Results: A significantly smaller air-bone gap (ABG) and lower air conduction thresholds after surgery were observed in the group of patients who underwent surgery with preoperative ABGs of less than 25 dB. Bone conduction thresholds improve in sABG group after surgery. Conclusions: The results after stapedotomies are good even if the preoperative air-bone gap is small and that the overall risk of hearing deterioration due to stapes surgery remains low. [less ▲]

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See detailHearing Preservation in Cochlear Implantation and Drug Treatment.
Barriat, Sébastien ULg; Poirrier, Anne-Lise ULg; Malgrange, Brigitte ULg et al

in Advances in Oto-Rhino-Laryngology (2010), 67

Insertion of an electrode array into the cochlea produces immediate damage to the inner ear, which is responsible for a hearing loss. In addition, a delayed hearing loss can be observed. In order to ... [more ▼]

Insertion of an electrode array into the cochlea produces immediate damage to the inner ear, which is responsible for a hearing loss. In addition, a delayed hearing loss can be observed. In order to maximize hearing preservation after insertion of an electrode and to enhance the performance of the cochlear implant, it has been proposed to deliver pharmacological agents to the inner ear. Molecules can be administered locally to the inner ear through a direct perilymphatic perfusion or through the round window membrane. These modalities of treatment have already been successfully applied to some patients with inner ear diseases. In this paper, we will review some basic aspects of drug delivery to the inner ear to prevent the degeneration of the neurosensory hair cells and auditory neurons, and the actual applicability to humans in order to maintain hearing function after the insertion of electrodes of a cochlear implant. [less ▲]

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