Développement de nouvelles benzènesulfonylurées diversement substituées en tant qu'antagonistes des récepteurs au thromboxane A2Bambi Nyanguile, Sylvie-Mireille ![]() Scientific conference (2012, December 22) Detailed reference viewed: 10 (1 ULg) Development of original 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas as thromboxane A2 receptor antagonistsBambi Nyanguile, Sylvie-Mireille ; Hanson, Julien ; et alPoster (2012, August) A series of novel 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas were synthesized. The newly synthesized compounds were tested in vitro and ex vivo as thromboxane A2 receptor antagonists. Some of the ... [more ▼] A series of novel 2-aryloxy/arylamino-5-cyanobenzenesulfonylureas were synthesized. The newly synthesized compounds were tested in vitro and ex vivo as thromboxane A2 receptor antagonists. Some of the test compounds showed potent thromboxane A2 receptor antagonist activity. Three compounds (7h, 8h and 8e) were identified as leads for further pharmacological and toxicological studies. [less ▲] Detailed reference viewed: 21 (1 ULg) Development of original diversely substituted benzenesulfonylureas as thromboxane A2 receptor antagonistsBambi Nyanguile, Sylvie-Mireille ; Hanson, Julien ; et alPoster (2012, May) Detailed reference viewed: 13 (1 ULg) Conception, synthèse et évaluation biologique de dérivés coumariniques en tant qu’agents anti-cancéreux potentielsHemmer, Marc ; Bambi Nyanguile, Sylvie-Mireille ; De Tullio, Pascal et alPoster (2009, May) Detailed reference viewed: 35 (19 ULg) |
||