References of "et al"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailFish consumption patterns and hair mercury levels in children and their mothers in 17 EU countries
Castano, Argelia; Cutanda, Francisco; Esteban, Marta et al

in Environmental Research (2015), 141

The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential ... [more ▼]

The toxicity of methylmercury (MeHg) in humans is well established and the main source of exposure is via the consumption of large marine fish and mammals. Of particular concern are the potential neurodevelopmental effects of early life exposure to low-​levels of MeHg. Therefore, it is important that pregnant women, children and women of childbearing age are, as far as possible, protected from MeHg exposure. Within the European project DEMOCOPHES, we have analyzed mercury (Hg) in hair in 1799 mother-​child pairs from 17 European countries using a strictly harmonized protocol for mercury anal. Parallel, harmonized questionnaires on dietary habits provided information on consumption patterns of fish and marine products. After hierarchical cluster anal. of consumption habits of the mother-​child pairs, the DEMOCOPHES cohort can be classified into two branches of approx. similar size: one with high fish consumption (H) and another with low consumption (L)​. All countries have representatives in both branches, but Belgium, Denmark, Spain, Portugal and Sweden have twice as many or more mother-​child pairs in H than in L. For Switzerland, Czech Republic, Hungary, Poland, Romania, Slovenia and Slovakia the situation is the opposite, with more representatives in L than H. There is a strong correlation (r=0.72) in hair mercury concn. between the mother and child in the same family, which indicates that they have a similar exposure situation. The clustering of mother-​child pairs on basis of their fish consumption revealed some interesting patterns. One is that for the same sea fish consumption, other food items of marine origin, like seafood products or shellfish contribute significantly to the mercury levels in hair. We conclude that addnl. studies are needed to assess and quantify exposure to mercury from seafood products, in particular. The cluster anal. also showed that 95​% of mothers who consume once per wk fish only, and no other marine products, have mercury levels 0.55 μg​/g. Thus, the 95th percentile of the distribution in this group is only around half the US-​EPA recommended threshold of 1 μg​/g mercury in hair. Consumption of freshwater fish played a minor role in contributing to mercury exposure in the studied cohort. The DEMOCOPHES data shows that there are significant differences in MeHg exposure across the EU and that exposure is highly correlated with consumption of fish and marine products. Fish and marine products are key components of a healthy human diet and are important both traditionally and culturally in many parts of Europe. Therefore, the communication of the potential risks of mercury exposure needs to be carefully balanced to take into account traditional and cultural values as well as the potential health benefits from fish consumption. European harmonized human biomonitoring programs provide an addnl. dimension to national HMB programs and can assist national authorities to tailor mitigation and adaptation strategies (dietary advice, risk communication, etc.) to their country's specific requirements. [less ▲]

Detailed reference viewed: 123 (21 ULiège)
Full Text
Peer Reviewed
See detailMercury analysis in hair: Comparability and quality assessment within the transnational COPHES/DEMOCOPHES project
Esteban, Marta; Schindler, Birgit K.; Jiménez-Guerrero, José A. et al

in Environmental Research (2015), 141

Human biomonitoring (HBM) is an effective tool for assessing actual exposure to chemicals that takes into account all routes of intake. Although hair analysis is considered to be an optimal biomarker for ... [more ▼]

Human biomonitoring (HBM) is an effective tool for assessing actual exposure to chemicals that takes into account all routes of intake. Although hair analysis is considered to be an optimal biomarker for assessing mercury exposure, the lack of harmonization as regards sampling and analytical procedures has often limited the comparison of data at national and international level. The European-funded projects COPHES and DEMOCOPHES developed and tested a harmonized European approach to Human Biomonitoring in response to the European Environment and Health Action Plan. Herein we describe the quality assurance program (QAP) for assessing mercury levels in hair samples from more than 1800 mother–child pairs recruited in 17 European countries. To ensure the comparability of the results, standard operating procedures (SOPs) for sampling and for mercury analysis were drafted and distributed to participating laboratories. Training sessions were organized for field workers and four external quality-assessment exercises (ICI/EQUAS), followed by the corresponding web conferences, were organized between March 2011 and February 2012. ICI/EQUAS used native hair samples at two mercury concentration ranges (0.20–0.71 and 0.80–1.63) per exercise. The results revealed relative standard deviations of 7.87–13.55% and 4.04–11.31% for the low and high mercury concentration ranges, respectively. A total of 16 out of 18 participating laboratories the QAP requirements and were allowed to analyze samples from the DEMOCOPHES pilot study. Web conferences after each ICI/EQUAS revealed this to be a new and effective tool for improving analytical performance and increasing capacity building. The procedure developed and tested in COPHES/DEMOCOPHES would be optimal for application on a global scale as regards implementation of the Minamata Convention on Mercury. [less ▲]

Detailed reference viewed: 37 (5 ULiège)
Full Text
Peer Reviewed
See detailStreptococcus agalactiae clones infecting humans were selected and fixed through the extensive use of tetracycline
Da Cunha, Violette; Davies, MR; Douarre, Pierre-Emmanuel et al

in Nature Communications (2014)

Streptococcus agalactiae (Group B Streptococcus, GBS) is a commensal of the digestive and genitourinary tracts of humans that emerged as the leading cause of bacterial neonatal infections in Europe and ... [more ▼]

Streptococcus agalactiae (Group B Streptococcus, GBS) is a commensal of the digestive and genitourinary tracts of humans that emerged as the leading cause of bacterial neonatal infections in Europe and North America during the 1960s. Due to the lack of epidemiological and genomic data, the reasons for this emergence are unknown. Here we show by com- parative genome analysis and phylogenetic reconstruction of 229 isolates that the rise of human GBS infections corresponds to the selection and worldwide dissemination of only a few clones. The parallel expansion of the clones is preceded by the insertion of integrative and conjugative elements conferring tetracycline resistance (TcR). Thus, we propose that the use of tetracycline from 1948 onwards led in humans to the complete replacement of a diverse GBS population by only few TcR clones particularly well adapted to their host, causing the observed emergence of GBS diseases in neonates. [less ▲]

Detailed reference viewed: 27 (4 ULiège)
Full Text
Peer Reviewed
See detailDevelopment of a Standard Reference Material for Metabolomics Research
Phinney, K; Ballihaut, G; Bedner, M et al

in Analytical Chemistry (2013), 85(24), 11732-11738

The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NIH), has developed a Standard Reference Material (SRM) to support technology ... [more ▼]

The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NIH), has developed a Standard Reference Material (SRM) to support technology development in metabolomics research. SRM 1950 Metabolites in Human Plasma is intended to have metabolite concentrations that are representative of those found in adult human plasma. The plasma used in the preparation of SRM 1950 was collected from both male and female donors, and donor ethnicity targets were selected based upon the ethnic makeup of the U.S. population. Metabolomics research is diverse in terms of both instrumentation and scientific goals. This SRM was designed to apply broadly to the field, not towards specific applications. Therefore, concentrations of approximately 100 analytes, including amino acids, fatty acids, trace elements, vitamins, hormones, selenoproteins, clinical markers, and perfluorinated compounds (PFCs), were determined. Value assignment measurements were performed by NIST and the Centers for Disease Control and Prevention (CDC). SRM 1950 is the first reference material developed specifically for metabolomics research. [less ▲]

Detailed reference viewed: 29 (3 ULiège)
Full Text
Peer Reviewed
See detailGenome-wide meta-analysis identifies new susceptibility loci for migraine.
SCHOENEN, Jean ULiege; Anttila, V; Winsvold BS et al

in Nature Genetics (2013), 45(8), 912-917

A genome wide association study of migraine subjects identifies several new susceptibility loci.

Detailed reference viewed: 17 (1 ULiège)
Full Text
Peer Reviewed
See detailThermal optimality of net ecosystem exchange of carbon dioxide and underlying mechanisms
Niu, Shuli; Fei, Shenfeng; Yuan, Wenping et al

in New Phytologist (2012), 194

• It is well established that individual organisms can acclimate and adapt to temperature to optimize their functioning. However, thermal optimization of ecosystems, as an assemblage of organisms, has not ... [more ▼]

• It is well established that individual organisms can acclimate and adapt to temperature to optimize their functioning. However, thermal optimization of ecosystems, as an assemblage of organisms, has not been examined at broad spatial and temporal scales. • Here, we compiled data from 169 globally distributed sites of eddy covariance and quantified the temperature response functions of net ecosystem exchange (NEE), an ecosystem- level property, to determine whether NEE shows thermal optimality and to explore the underlying mechanisms. • We found that the temperature response of NEE followed a peak curve, with the optimum temperature (corresponding to the maximum magnitude of NEE) being positively correlated with annual mean temperature over years and across sites. Shifts of the optimum temperature of NEE were mostly a result of temperature acclimation of gross primary productivity (upward shift of optimum temperature) rather than changes in the temperature sensitivity of ecosystem respiration. • Ecosystem-level thermal optimality is a newly revealed ecosystem property, presumably reflecting associated evolutionary adaptation of organisms within ecosystems, and has the potential to significantly regulate ecosystem–climate change feedbacks. The thermal optimality of NEE has implications for understanding fundamental properties of ecosystems in changing environments and benchmarking global models. [less ▲]

Detailed reference viewed: 18 (2 ULiège)
Full Text
Peer Reviewed
See detailClinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project.
McHugh, David; Cameron, C. A.; Abdenur, J. E. et al

in Genetics in Medicine : Official Journal of the American College of Medical Genetics (2011), 13(3), 230-54

Detailed reference viewed: 36 (4 ULiège)
Peer Reviewed
See detailFrom Non-invasive Site Characterization to Site Amplification: Recent Advances in the Use of Ambient Vibration Measurements.
Bard, P-Y; et al.; Havenith, Hans-Balder ULiege

in Geotechnical, Geological and Earthquake Engineering : Earthquake Engineering in Europe (2010)

Detailed reference viewed: 45 (0 ULiège)
Full Text
Peer Reviewed
See detailUsing passive nonlinear targeted energy transfer to stabilize drill-stringsystems
Viguié, Régis ULiege; Kerschen, Gaëtan ULiege; Golinval, Jean-Claude ULiege et al

in Mechanical Systems & Signal Processing (2009), 23

Torsional vibrations of drill strings used in drilling oil and gas wells arises from a complex interaction of the dynamics of the drilling structure with speed-dependent effective rock-cutting forces ... [more ▼]

Torsional vibrations of drill strings used in drilling oil and gas wells arises from a complex interaction of the dynamics of the drilling structure with speed-dependent effective rock-cutting forces. These forces are often difficult to model, and contribute substantially to the instability problems of controlling the drilling operation so as to produce steady cutting. In this work we show how nonlinear passive targeted energy transfer to a lightweight attachment can be used to passively control these instabilities. This is performed by means of a nonlinear energy sink (NES), a lightweight attachment which has been shown to be effective in reducing or even completely eliminating self-excited motions in aeroelastic and other systems. The NES is a completely passive, inherently broadband vibration absorber capable of attracting and dissipating vibrational energy from the primary structure to which it is attached, in this case a nonlinear discontinuous model of a drill-string system. In this paper we describe a prototypical drill string-NES system, briefly discuss some of the analytical and computational tools suitable for its analysis, and then concentrate on mathematical results on the efficacy of the NES in this application and their physical interpretation. [less ▲]

Detailed reference viewed: 50 (6 ULiège)
Peer Reviewed
See detailCerebral correlates of false memories and illusory recollection after sleep and sleep deprivation.
Darsaud, A.; Dehon, Hedwige ULiege; et al.

Poster (2008, May)

Detailed reference viewed: 11 (1 ULiège)
Full Text
Peer Reviewed
See detailL'Hôpital général de référence en Ituri : des normes sanitaires à la réalité
Karemere, Hermes; Porignon, Denis ULiege; et al

in Revue d'Epidémiologie et de Santé Publique = Epidemiology and Public Health (2008)

Detailed reference viewed: 16 (2 ULiège)
Full Text
See detailREVIEW OF ON-LINE DYNAMIC SECURITY ASSESSMENT TOOLS AND TECHNIQUES
Morison, Kip; Glavic, Mevludin ULiege; et al.

Report (2007)

The CIGRE WG C4.601 on Power System Security Assessment was formed in August 2004, at the CIGRE Session 2004 and was given the charter to specifically look at the following needs in the industry: 1. The ... [more ▼]

The CIGRE WG C4.601 on Power System Security Assessment was formed in August 2004, at the CIGRE Session 2004 and was given the charter to specifically look at the following needs in the industry: 1. The design of controls to enhance system security. This includes local device controls as well as system wide area controls and remedial action schemes. 2. Modeling of existing and new equipment required for power system analysis. (In this task it was felt that the most pertinent and timely activity was to look at the modeling and dynamic performance of wind generation systems.) 3. The design of monitoring systems for real time stability evaluation and control. 4. New analytical techniques for assessment of power system security. In addition to advances in computational methods, this includes the development of emerging approaches such as risk-based security assessment and the application of intelligent technologies. To this end, all of the above subject matters were tackled by the Working Group. More specifically, of the more than one hundred members and contributors to the work, three adhoc groups were developed within the Working Group, each given the task to address one of the first three subject matters above. The fourth task is one that the working group as a whole has presently started on, after having finished the other three tasks. The three completed tasks have resulted in the publication of three CIGRE Technical Brochures. These are: • CIGRE Technical Brochure on Wide Area Monitoring and Control For Transmission Capability Enhancement (this effort was lead by C. Rehtanz) • CIGRE Technical Brochure on Modeling and Dynamic Behavior of Wind Generation as it Relates to Power System Control and Dynamic Performance (this effort was lead by P. Pourbeik) • CIGRE Technical Brochure on Review of On-Line Dynamic Security Assessment Tools and Techniques (this effort was lead by K. Morison) During the course of the work, in addition to the formally elected WG members a large number of others contributed significantly to these efforts. All have been properly acknowledged. The combined group of members and contributors constituted 125 experts from 25 countries. These included experts from equipment manufacturers, utility engineers, consultants and research organizations around the world. The work on the three Technical Brochures mentioned above was completed in December 2006, with final reviews and approvals before publication occurring in early 2007. Thus, the work took nearly two and a half years to complete. All three documents constitute timely and valuable information for transmission system planer, operators, reliability organization and engineers in research and consulting firms. As stated previously, the Working Group is currently working on its last assignments (item 4. above). It is expected that this will be reported on in the near future. [less ▲]

Detailed reference viewed: 64 (0 ULiège)
See detailAstroPoles : Astronomy from the Polar Plateaus; The astronomy program for the International Polar Year
Burton, M.; et al.; Surdej, Jean ULiege et al

Poster (2006, August)

Detailed reference viewed: 15 (0 ULiège)
Full Text
See detailInformation Technology - Enhancements to LOTOS (E-LOTOS)
Leduc, Guy ULiege; et al.

Report (2001)

Detailed reference viewed: 19 (2 ULiège)
See detailHealth Services in Rwanda: A Review of Public Expenditure in 1998.
Porignon, Denis ULiege; et al

Report (1999)

Detailed reference viewed: 16 (0 ULiège)