References of "de Landsheere, Christian"
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See detailHow light and occupational therapy intervention could fight some psychogeriatric symptoms
Maggi, Patrick ULg; Bassain, Fatima; Gosset, Christiane ULg et al

Conference (2014, November 27)

Purpose: Aggregated results of systematic reviews separately show how light used as a treatment and some occupational therapy interventions could have a positive impact on psychobehavioural disorders in ... [more ▼]

Purpose: Aggregated results of systematic reviews separately show how light used as a treatment and some occupational therapy interventions could have a positive impact on psychobehavioural disorders in older people. Since the beginning of June 2014 the Walloon Government has been financing a project which consists of a non-pharmacological approach that combines light and occupational therapy for a psychogeriatric population with specific symptoms: spatial and temporal disorientations, apathy, depression, agitation, anxiety, confusion and circadian disorder. The objective of this abstract is to expose the assumptions that the combination of two different light devices and one specific occupational therapy program could have an impact on the different symptoms of a psychogeriatric population. Methods: To build our hypothesis, two literature reviews have been achieved. The first one concerning the use of light as therapy gathered 30 studies while the other one about occupational therapy activities collected 35 articles. Results: Despite of a heterogeneity between studies dealing with light and occupational therapy, the combination of these two non-pharmacological interventions might fight the depressive syndrome, reduce the temporal disorientation thanks to a regularity in the period of activity, restore the circadian rhythm and so reduce some troubles that can be linked to them: sleep disorder, risk of fall, apathy, agitation, behavioural and cognitive troubles (attention, concentration). Moreover, one of the two light devices used which can modulate the light intensity according to the rooms might reduce the spatial disorientation if it’s employed as a landmark. Conclusions: Based on literature reviews and our experience into this field it’s seems that a non-pharmacological approach involving light and occupational therapy intervention could have a positive effect on symptoms of psychogeriatric population. In admitting that those effects are becoming true after experimentation and analyses, we can also expect an improvement of the quality of life. [less ▲]

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See detailThe role of wrist actigraphy in the evaluation and safety of patients in psychogeriatric ward
GILLAIN, Daniel ULg; Schyns, Edwin ULg; LEJEUNE, Christophe ULg et al

in European Geriatric Medicine (2013), 4(S1),

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See detailEffect of Spinal Cord Stimulation on Regional Myocardial Perfusion Assessed by Positron Emission Tomography
de Landsheere, Christian ULg; Mannheimer, C.; Habets, A. et al

in American Journal of Cardiology (1992), 69(14), 1143-9

Spinal cord stimulation (SCS) can relieve symptoms in patients with severe angina pectoris refractory to conventional medical or surgical therapy. This symptomatic improvement may result from decreased ... [more ▼]

Spinal cord stimulation (SCS) can relieve symptoms in patients with severe angina pectoris refractory to conventional medical or surgical therapy. This symptomatic improvement may result from decreased myocardial ischemia. To test this hypothesis, positron emission tomography (PET) and potassium-38 as a flow tracer were used in 8 patients for the quantitative evaluation of regional myocardial perfusion at rest and after exercise, before and during SCS. Potassium uptake was evaluated as myocardial clearance (flow times net extraction) in ml/min/100 g. Tomographic segments were categorized as nonaffected and affected on the basis of the absence or presence of arterial stenosis on coronary angiography and on the basis of thallium scintigraphic data. In nonaffected segments, before SCS, regional myocardial clearance significantly increased from rest (28 +/- 4) to exercise (47 +/- 13 clearance units; p less than 0.004). A similar increase occurred after SCS. In affected segments, before SCS, regional myocardial clearance barely increased (p = 0.065) from rest (26 +/- 6) to exercise (33 less than or equal to 12). In comparison, after SCS, the resting regional myocardial clearance was slightly elevated (29 +/- 8) reflecting an increased double product, but did not increase (p = 0.192) with exercise (34 +/- 12). However, the magnitude and duration of ST-segment depression decreased during treatment with SCS. Anginal pain occurred in all patients during control exercise, but was attenuated in all but one with SCS. These results indicate that SCS improves exercise-induced angina and electrocardiographic signs of ischemia but this influence does not appear to be mediated by changes in regional myocardial perfusion. [less ▲]

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See detailAutomated Production of Potassium-38 for the Study of Myocardial Perfusion Using Positron Emission Tomography
Guillaume, Marcel; de Landsheere, Christian ULg; Rigo, Pierre ULg et al

in International Journal of Radiation Applications and Instrumentation. Part A : Applied Radiation and Isotopes (1988), 39(2), 97-107

The 35Cl(alpha, n)38K nuclear reaction was developed for the routine cyclotron production of repeated multimillicurie batches of 38K for dynamic studies of regional tissue perfusion with positron emission ... [more ▼]

The 35Cl(alpha, n)38K nuclear reaction was developed for the routine cyclotron production of repeated multimillicurie batches of 38K for dynamic studies of regional tissue perfusion with positron emission tomography. The objective is to make this isotope available as an alternative to the use of [13N]NH3 and 82Rb for the investigation of flow in experimental and clinical use. A sodium chloride powder target mounted on a water-cooled nickel backing is bombarded with 26 MeV helium-4 ions at a maximum beam current of 25 microA. The target is remotely disconnected from the bombardment port, transported to a hot cell and entirely processed by a computer-controlled system within a total time of less than 4 min. The final pyrogen-free isotonic and sterile solution of 38K has a radionuclidic purity of more than 99.99%. A typical yield of 19 +/- 2 mCi of 38K is obtained at the end of a 30 min bombardment at 10 microA. The production rate at saturation can therefore be estimated to 2.05 +/- 0.2 mCi/microA. [less ▲]

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