  Sustained antihypertensive activity of telmisartan compared with valsartan; Krzesinski, Jean-Marie  ; et alin Blood Pressure Monitoring (2004), 9 Early morning bood pressure (BP) surge and 24h mean BP are linked to target-organ damage and cardiovascular events. Antihypertensive agents should sustain BP control, particularly in the last 6h of the ... [more ▼] Early morning bood pressure (BP) surge and 24h mean BP are linked to target-organ damage and cardiovascular events. Antihypertensive agents should sustain BP control, particularly in the last 6h of the dosing interval or if dosing is missed. The efficacies of the long half-life telmisartan compared with shorter half-life valsartan in the last 6h of the dosing interval following active treatment and during 24h after a missed dose were compared. [less ▲] Detailed reference viewed: 23 (2 ULg) Sustained antihypertensive activity of telmisartan compared vs valsartan; Krzesinski, Jean-Marie ; et alin Journal of Hypertension (Supplement) (2004), 22(suppl 1), 196 DBP reduction in the last 6 h of the once-daily dosing interval and 24-h mean DBP control when a dose is missed are significantly superior with telmisartan than with valsartan. Thus, telmisartan due to ... [more ▼] DBP reduction in the last 6 h of the once-daily dosing interval and 24-h mean DBP control when a dose is missed are significantly superior with telmisartan than with valsartan. Thus, telmisartan due to its longer half -life offers more sustained BP control, especially at the end of the dosing period and provides sustained efficacy in poorly compliant patients. [less ▲] Detailed reference viewed: 30 (8 ULg) |
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