References of "Vranken, Laura"
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See detailComparison of cardiac biomarker fluctuation in runners of marathons, semi-marathons and untrained runners
LE GOFF, Caroline ULg; VRANKEN, Laura ULg; van Nueten, Jan et al

in Clinical Chemistry & Laboratory Medicine (2017, June)

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See detailEtude rétrospective du bilan thyroïdien: définition de valeurs de référence pédiatriques
LADANG, Aurélie ULg; VRANKEN, Laura ULg; LUYCKX, Françoise ULg et al

in Revue Médicale de Liège (2017)

Defining reference range is an essential tool for diagnostic. Age and sexe influences on thyroid hormone levels have been already discussed. In this study, we are defining a new pediatric reference range ... [more ▼]

Defining reference range is an essential tool for diagnostic. Age and sexe influences on thyroid hormone levels have been already discussed. In this study, we are defining a new pediatric reference range for TSH, FT3 and FT4 for Cobas C6000 analyzer. To do so, we have taken in account 0 to 18 year old outclinic patients. During the first year of life, thyroid hormone levels change dramatically before getting stabilized around 3 years old. We also compared our results to those obtained in a Canadian large-scale prospective study (the CALIPER initiative). [less ▲]

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See detailUnexpected high levels of Cobalamin (Vitamin B12): Numerous interferences are decreased by PEG treatment.
LADANG, Aurélie ULg; VRANKEN, Laura ULg; CAVALIER, Etienne ULg

Poster (2016, October)

Cobalamin (Vitamin B12) deficiency is a common cause of anemia. High levels of serum cobalamin is mainly due to cobalamin supplementation. It has also been associated with hematological malignancies ... [more ▼]

Cobalamin (Vitamin B12) deficiency is a common cause of anemia. High levels of serum cobalamin is mainly due to cobalamin supplementation. It has also been associated with hematological malignancies, liver or renal diseases. Cobalamin is sometimes found elevated in autoimmune disorders and infectious diseases but concerns are raised on the fact that those serum increases might be due to interference with immunoassays. Those data’s shed the lights on the high prevalence of interference in patients with unexpected high cobalamin level. Precipitation with PEG appears to be an easy and costless method to increase the reliability of cobalamin dosage. In accordance with our results, we recommand to treat systematically every serum with a cobalamin >1500 ng/L. [less ▲]

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See detailPrévalence de l’hypovitaminose D chez la femme enceinte : quelle est la situation en région liégeoise ?
VRANKEN, Laura ULg

Master of advanced studies dissertation (2016)

Vitamin D deficiency is a worldwide health problem, also during pregnancy, especially in women with limited access to sunlight due to minimal outdoor activity or heavy use of sunscreen, cultural practices ... [more ▼]

Vitamin D deficiency is a worldwide health problem, also during pregnancy, especially in women with limited access to sunlight due to minimal outdoor activity or heavy use of sunscreen, cultural practices or traditional clothing, and among women with dark skin pigmentation and poor dietary habits. Inadequate maternal vitamin D status in pregnancy is associated with poor fetal growth, impaired bone development and rickets in infants after birth. Furthermore, higher rates of preeclampsia and gestational diabetes are associated with low maternal vitamin D status during pregnancy. Toxicity of vitamin D is rare. Most countries recommend vitamin D supplementation during pregnancy but guidelines are controversial and inadequate compared to real mother’s and child’s needs. Wath’s the best strategy to follow and supplement mother during pregnancy? [less ▲]

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See detailUsing S-Monovette° lower the rate of hemolysed specimen from a belgian academic emergency department
VRANKEN, Laura ULg; DELCOUR, Sandra ULg; CAVALIER, Etienne ULg

in Clinical Chemistry & Laboratory Medicine (2015, October)

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See detailActive vitamin B12: detection and clinical implications
VRANKEN, Laura ULg

Conference (2012, October 25)

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See detailThe thyrogastric syndrome : an under diagnosed etiology for acquired gastric neuroendocrine tumors. A case report
VALDES SOCIN, Hernan Gonzalo ULg; LOLY, Jean ULg; GAST, Pierrette ULg et al

in Abstract Book - 13th International Workshop on Multiple Endocrine Neoplasia (2012, September)

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See detailInterpretation of serum PTH concentrations with different kits in dialysis patients according to the KDIGO guidelines: importance of the reference (normal) values
CAVALIER, Etienne ULg; DELANAYE, Pierre ULg; VRANKEN, Laura ULg et al

in Nephrology Dialysis Transplantation (2012), 27

Background. The recommended target range for serum parathyroid hormone (PTH) in dialysis patients has changed from 150 to 300 pg/mL in the KDOQI guidelines to two to nine times the upper normal limit in ... [more ▼]

Background. The recommended target range for serum parathyroid hormone (PTH) in dialysis patients has changed from 150 to 300 pg/mL in the KDOQI guidelines to two to nine times the upper normal limit in the KDIGO ones. Although inclusion/exclusion criteria for the reference population are highly important, they are usually not mentioned in the commercial kits. In this study, we used the same reference population of vitamin D-replete normal subjects to establish reference values for 10 commercial PTH kits. We evaluated whether this may improve the classification of dialysis patients according to the KDIGO compared to the use of reference values proposed by the manufacturers. Methods. We measured serum PTH with 10 different kits in 149 haemodialysis patients, and 240 25-OH-vitamin D-replete (>75 nmol/L) individuals with an estimated glomerular filtration rate >60 mL/min/1.73 m2. Results. For the 10 kits, our upper normal limit was lower than those of the manufacturers. The difference was, however, variable from one kit to another. The two kits that yielded the lowest and the highest absolute concentrations classified differently 84/149 patients (56.4%) according to the KDOQI and 53/149 (36.2%) according to the KDIGO using the manufacturers’ normal value.Using our normal values significantly decreased the discrepancies with 24/149 patients (16.1%) being still classified differently. Taking the measurement uncertainty into consideration, 8% of the patients only remained differently classified by these two kits. Conclusions. Using the same vitamin-D-replete population to establish the reference range for 10 commercial PTH kits significantly improved the classification of haemodialysis patients according to the KDIGO target range. [less ▲]

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