References of "Votion, Dominique"
     in
Bookmark and Share    
Full Text
See detailMetabolic responses to exercise and training
Votion, Dominique ULg

in Hinchcliff K.W; Kaneps A.J.; Geor R.J. (Eds.) Equine Sport Medicine and Surgery (2014)

This chapter reviews the whole-body and muscular metabolic responses and also describes the effects of training adaptation on these processes.

Detailed reference viewed: 20 (10 ULg)
Full Text
See detailProceedings of the 3rd Scientific Meeting of the Faculty of Veterinary Medicine
Bayrou, Calixte ULg; Cabaraux, Jean-François ULg; Delguste, Catherine ULg et al

Book published by Presses de la Faculté de Médecine Vétérinaire (2013)

Detailed reference viewed: 44 (18 ULg)
Full Text
See detailManaging acute myopathies
Votion, Dominique ULg

in In proceedings: 51th British Equine Veterinary Association (BEVA) Congress (2013, September)

Detailed reference viewed: 26 (7 ULg)
Full Text
See detailAtypical myopathy: epidemiology and aetiopathogenesis
Votion, Dominique ULg

in In proceedings: 51th British Equine Veterinary Association (BEVA) Congress (2013, September)

Detailed reference viewed: 59 (1 ULg)
Full Text
Peer Reviewed
See detailThe challenge of understanding myopathies in horses using permeabilized muscle cells
Votion, Dominique ULg; Mouithys-Mickalad, Ange ULg; Ceusters, Justine ULg et al

in In proceedings 9th Conference on Mitochondrial Physiology (2013, September)

Detailed reference viewed: 39 (19 ULg)
Full Text
See detailPrédiction des performances sportives et détection précoce des myopathies par respirométrie à haute résolution
Votion, Dominique ULg; Serteyn, Didier ULg

in cheval athlète, stress oxydant & inflammation (2013, June 07)

Detailed reference viewed: 44 (18 ULg)
Full Text
Peer Reviewed
See detailIdentification of methylenecyclopropyl acetic acid in serum of European horses with atypical myopathy
Votion, Dominique ULg; van Galen, G; Sweetan et al

in Equine Veterinary Journal (2013)

Detailed reference viewed: 144 (24 ULg)
Full Text
Peer Reviewed
See detailManagement of cases suffering from atypical myopathy: Interpretations of descriptive, epidemiological and pathophysiological findings. Part 2: Muscular, urinary, respiratory and hepatic care, and inflammatory/ infectious status
Van Galen, Gaby ULg; Votion, Dominique ULg

in Equine Veterinary Education (2013), 25(6), 308-314

Atypical myopathy is highly fatal, but about a quarter of affected horses survive. This highlights the need for provision of supportive treatment for these patients. This review is a practical guideline ... [more ▼]

Atypical myopathy is highly fatal, but about a quarter of affected horses survive. This highlights the need for provision of supportive treatment for these patients. This review is a practical guideline for equine practitioners and includes suggestions for close monitoring of involved organ systems and discusses options of supportive treatment based on current knowledge of the condition. Part 2 covers the muscular, urinary, respiratory and hepatic systems, and the general inflammatory/infectious status of the case. [less ▲]

Detailed reference viewed: 230 (33 ULg)
Full Text
Peer Reviewed
See detailTraditional and quantitative assessment of acid-base and shock variables in horses with atypical myopathy
van Galen, G; Cerri, Simona ULg; Porter, S et al

in Journal of Veterinary Internal Medicine (2013), 27(1), 186-193

BACKGROUND: Descriptions of acid-base disturbances in atypical myopathy (AM) are limited. OBJECTIVES: Describe and compare traditional and quantitative acid-base abnormalities and cardiovascular shock ... [more ▼]

BACKGROUND: Descriptions of acid-base disturbances in atypical myopathy (AM) are limited. OBJECTIVES: Describe and compare traditional and quantitative acid-base abnormalities and cardiovascular shock status in horses with AM at admission. ANIMALS: 34 horses with AM, 15 healthy controls. METHODS: Retrospective case-control study. Records were searched for shock variables (packed cell volume [PCV], blood urea nitrogen [BUN], heart and respiratory rate) and acid-base variables (venous blood gas analysis, electrolytes, total protein, lactate) on admission. Base excess (BE) of free water (BEfw), chloride (BEcl), total protein (BEtp), and unidentified anions (BEua), anion gap (AG), measured strong ion difference (SIDm), and concentration of total nonvolatile weak acids ([Atot]) were calculated. Acid-base classifications, using simplified strong ion model and traditional approach, and shock grades were assigned. A 2-sample Wilcoxon rank-sum test and Bonferroni correction compared variables in AM cases versus control horses. Significance was P < .05/16 for acid-base and P < .05/5 for shock variables. RESULTS: Tachycardia, tachypnea, and normal to increased PCV and BUN were common in AM cases. Respiratory, metabolic acid-base alterations, or both were mainly caused by respiratory alkalosis, lactic acidosis, and SIDm alkalosis, alone or in combination. Evaluated variables (except pH, potassium concentration, total protein, and related calculations) were significantly different (P < .001) between AM cases and control horses. The strong ion model provided a more accurate assessment than the traditional approach and identified mixed derangements. CONCLUSIONS AND CLINICAL IMPORTANCE: Acid-base derangements should be evaluated in horses with AM and this preferably with the strong ion model. [less ▲]

Detailed reference viewed: 15 (6 ULg)
Full Text
Peer Reviewed
See detailAltered mitochondrial oxidative phosphorylation capacity in horses suffering from polysaccharide storage myopathy
Tosi, Irène ULg; Art, Tatiana ULg; Cassart, Dominique ULg et al

Poster (2013)

Introduction: Exertional rhabdomyolyses are a common cause of exercise intolerance in the equine athlete, and Polysaccharide Storage Myopathy (PSSM) is a widely described muscular pathology. It is ... [more ▼]

Introduction: Exertional rhabdomyolyses are a common cause of exercise intolerance in the equine athlete, and Polysaccharide Storage Myopathy (PSSM) is a widely described muscular pathology. It is characterized by an accumulation of abnormal glycogen in myofibers due to a genetic defect in the skeletal muscle glycogen synthase (GYS1) enzyme. We hypothesized that the energetic production through the oxidative phosphorylation (OXPHOS) in muscular mitochondria might be impaired in type-1 PSSM-affected horses. Material and Methods: Eight horses with a history of exertional rhabdomyolysis were tested for the GYS1 mutation. Muscle biopsies were collected and used for histological analysis and high resolution respirometry (HRR). HRR values from 3 groups of horses (PSSM-positive horses, horses with a history of myopathy but negative to PSSM and healthy controls) were compared using a linear mixed model to take into account repeated (2-3 times) measurements made for each horse. Results: In four horses histology revealed an accumulation of abnormal glycogen in myofibers. A severe depression of the maximal OXPHOS capacity was observed by HRR in all horses with exertional rhabodmyolysis, with lower values in PSSM-positive cases. Conclusions: Our study shows a severe decreased OXPHOS capacity in PSSM-affected horses. PSSM is considered primarily a defect in glycogen synthesis but altered OXPHOS might play a central role in its pathogenesis. [less ▲]

Detailed reference viewed: 32 (2 ULg)
Full Text
Peer Reviewed
See detailManagement of cases suffering from atypical myopathy:Interpretations of descriptive, epidemiological and pathophysiological findings. Part 1: First aid, cardiovascular, nutritional and digestive care
Van Galen, Gaby ULg; Votion, Dominique ULg

in Equine Veterinary Education (2013), 25(5), 264-270

Atypical myopathy is highly fatal, but about a quarter of affected horses survive. This highlights the need for provision of supportive treatment for these cases. This review is a practical guideline for ... [more ▼]

Atypical myopathy is highly fatal, but about a quarter of affected horses survive. This highlights the need for provision of supportive treatment for these cases. This review is a practical guideline for equine practitioners and includes suggestions for close monitoring of involved organ systems and discusses options of supportive treatment based on current knowledge of the condition. [less ▲]

Detailed reference viewed: 225 (18 ULg)
Full Text
See detailThe cause of atypical myopathy in grazing European horses revealed
Votion, Dominique ULg

Scientific conference (2012, December 11)

Detailed reference viewed: 110 (15 ULg)
Full Text
See detailProceedings of the 2nd Scientific Meeting of the Faculty of Veterinary Medicine (University of Liège – Belgium)
Bayrou, Calixte ULg; Cabaraux, Jean-François ULg; Delguste, Catherine ULg et al

Book published by Presses de la Faculté de Médecine vétérinaire de l’Université de Liège (2012)

Detailed reference viewed: 40 (11 ULg)
Full Text
Peer Reviewed
See detailPhysical Fitness and Mitochondrial Respiratory Capacity in Horse Skeletal Muscle
Votion, Dominique ULg; Gnaiger, Erich; Lemieux, Hélène et al

in PLoS ONE (2012), 7(4), 1-12

We applied high-resolution respirometry and multiple substrate-uncoupler-inhibitor titration protocols to study mitochondrial physiology in small (1.0–2.5 mg) permeabilized muscle fibres sampled from ... [more ▼]

We applied high-resolution respirometry and multiple substrate-uncoupler-inhibitor titration protocols to study mitochondrial physiology in small (1.0–2.5 mg) permeabilized muscle fibres sampled from triceps brachii of healthy horses. The present investigation on horse skeletal muscle has tested the methodology used to study mitochondrial function in muscle microbiopsies by high-resolution respirometry to define reference protocols for horses (from sampling procedure to data analysis). [less ▲]

Detailed reference viewed: 38 (20 ULg)
Full Text
See detailWhat have the last outbreaks of atypical myopathy in Europe told us: new treatment plans
Van Galen, Gaby ULg; Votion, Dominique ULg

in Verwilghen, Denis; Van Galen, Gaby; Busoni, Valeria (Eds.) Belgian International Congress: Hippos 2012 (2012, February)

Management and treatment of atypical myopathy cases

Detailed reference viewed: 120 (20 ULg)
Full Text
See detailWhat have the last outbreaks of atypical myopathy in Europe told us: new epidemiological evidence.
Votion, Dominique ULg

in Verwilghen, Denis; Van Galen, Gaby; Busoni, Valeria (Eds.) Belgian International Congress: Hippos 2012 (2012, February)

Atypical myopathy outbreaks are of an acute and unexpected nature and the information given in this review aims at helping equine practitioners in the recognition and handling of a suspected case in the ... [more ▼]

Atypical myopathy outbreaks are of an acute and unexpected nature and the information given in this review aims at helping equine practitioners in the recognition and handling of a suspected case in the event of AM outbreaks. So, this review (1) describes the diagnostic tools for AM, (2) reports prognostic criteria, and (3) lists preventive measures based on recent epidemiological surveys. [less ▲]

Detailed reference viewed: 65 (7 ULg)
Full Text
See detailSystemisch-entzuendliche Reaktion beim Hochleistungssportpferd
Sandersen, Charlotte ULg; Lejeune, Jean-Philippe ULg; Votion, Dominique ULg et al

Book published by Leipziger Blaue Hefte (2012)

Detailed reference viewed: 31 (7 ULg)