References of "Voncken, Audrey"
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See detailDevelopmental defects in zebrafish for classification of EGF pathway inhibitors.
Pruvot, Benoist ULg; Curé, Yoann ULg; Djiotsa, Joachim et al

in Toxicology and Applied Pharmacology (2014), 274

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See detailA panel of biological tests reveals developmental effects of pharmaceutical pollutants on late stage zebrafish embryos.
Pruvot, Benoist ULg; Quiroz O' Donova, Yobhana ULg; Voncken, Audrey ULg et al

in Reproductive Toxicology (2012)

Standard toxicological assays using the zebrafish model system evaluate lethality and teratogenicity upon exposure during the first two days after fertilization. We tested the biological effects of ... [more ▼]

Standard toxicological assays using the zebrafish model system evaluate lethality and teratogenicity upon exposure during the first two days after fertilization. We tested the biological effects of several widely used drugs on zebrafish by acute treatment for 24hours starting at late embryonic stages, between 48 and 72hours post-fertilization. For 4 out of 6 compounds, we observed a higher sensitivity of late stage zebrafish embryos for general toxicity (lethality) compared to younger embryos. Morphological defects such as edema, body curvature, delayed growth, decreased heart rate and locomotion were observed for each of the compounds tested, often at sublethal concentrations. Gene expression studies on a set of four selected genes revealed a specific regulatory pattern for the different compounds tested. Our results allow us to compare various toxicological endpoints and may contribute to the design of a rational high throughput approach using the zebrafish model. [less ▲]

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See detailZebrafish as model in toxicology/pharmacology.
Voncken, Audrey ULg; Piot, Amandine ULg; Stern, Olivier ULg et al

Poster (2010, March 17)

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See detailOptimizing active avoidance conditioning for high-throughput behavioral and cognitive screening in fish. Proceedings of Measuring behaviour
Ylieff, Marc ULg; Ferrara, André ULg; Fagniart, C. et al

in A.J. Spink et al. (Ed.) Proceedings of Measuring Behaviour (2008)

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