  Development of a Chitosan Nanofibrillar Scaffold for Skin Repair and Regeneration.Tchemtchoua Tateu, Victor  ; ; Aqil, Abdelhafid et alin Biomacromolecules (2011), 12 The final goal of the present study was the development of a 3-D chitosan dressing that would shorten the healing time of skin wounds by stimulating migration, invasion, and proliferation of the relevant ... [more ▼] The final goal of the present study was the development of a 3-D chitosan dressing that would shorten the healing time of skin wounds by stimulating migration, invasion, and proliferation of the relevant cutaneous resident cells. Three-dimensional chitosan nanofibrillar scaffolds produced by electrospinning were compared with evaporated films and freeze-dried sponges for their biological properties. The nanofibrillar structure strongly improved cell adhesion and proliferation in vitro. When implanted in mice, the nanofibrillar scaffold was colonized by mesenchymal cells and blood vessels. Accumulation of collagen fibrils was also observed. In contrast, sponges induced a foreign body granuloma. When used as a dressing covering full-thickness skin wounds in mice, chitosan nanofibrils induced a faster regeneration of both the epidermis and dermis compartments. Altogether our data illustrate the critical importance of the nanofibrillar structure of chitosan devices for their full biocompatibility and demonstrate the significant beneficial effect of chitosan as a wound-healing biomaterial. [less ▲] Detailed reference viewed: 39 (18 ULg) Comparison of Spectral Colorimetric Measurements vs. Color Pictures in DermatologyBlain, Pascal ; ; et alPoster (2010, April 13) We studied scars and wounds depths and surfaces thanks to our interferometric fringes projector 3D scanner1, 2. Color information of a wound indicates its deterioration level. That’s why the visual color ... [more ▼] We studied scars and wounds depths and surfaces thanks to our interferometric fringes projector 3D scanner1, 2. Color information of a wound indicates its deterioration level. That’s why the visual color restitution, as realistic as possible, is a highly important parameter. Firstly our acquired 3D pictures were color mapped with an image recorded by a RGB camera. The results were not efficient enough. In order to improve our technique and provide more precise information, we add a spectral characterization to the set-up. Before adding the spectral information and a realistic color mapping to the 3D measurements, we evaluate the performances of colorimetric measurements. The tests have been made on mice with scars on their back. [less ▲] Detailed reference viewed: 9 (0 ULg)En chemin vers les cancers photo-induits.Pierard, Gérald ; ; et alin Skin (2009), 12 Detailed reference viewed: 53 (25 ULg)Scedosporium apiospermum septicemia following a wedge excision of an ingrown toenail.Vanhooteghem, Olivier ; Gillard, Patricia ; Dezfoulian, Bita et alin International Journal of Dermatology (2009), 48(10), 1137-1139 Detailed reference viewed: 5 (0 ULg)Schöpf-Schulz-Passarge syndrome with pili torti: a new association?Szepetiuk, Grégory ; Vanhooteghem, Olivier ; et alin European Journal of Dermatology (2009), 19(5), 1-2 Detailed reference viewed: 24 (5 ULg)Un ongle d'inclusion: une complication de la cure chirurgicale d'ongle incarne selon la technique de ZadikVanhooteghem, Olivier ; ; André, Jean-François et alin Annales de Dermatologie et de Vénéréologie (2006), 133(12), 1009-10 Detailed reference viewed: 24 (1 ULg)Le lichen sclereux vulvaireGillard, Patricia ; Vanhooteghem, Olivier ; Richert, Bertrand et alin Revue Médicale de Liège (2005), 60(7-8), 656-660 Vulvar lichen sclerosus is a frequent mucocutaneous disease especially affecting 50 to 60 year-old women but with a possible onset at very young age. Symptoms are most disabling including pruritus and ... [more ▼] Vulvar lichen sclerosus is a frequent mucocutaneous disease especially affecting 50 to 60 year-old women but with a possible onset at very young age. Symptoms are most disabling including pruritus and dyspareunia. Vulvar mucosa gradually becomes more white and atrophied. Degeneration into epidermoid carcinoma is possible. Treatment only consists of topical corticosteroids. [less ▲] Detailed reference viewed: 124 (2 ULg)Cheloide et cicatrice hypertrophique; Vanhooteghem, Olivier ; Richert, Bertrand et alin Annales de Dermatologie et de Vénéréologie (2005), 132(4), 384-7 Detailed reference viewed: 33 (0 ULg)Osteo-onychodysplasie héréditaire (Nail Patella Syndrome)Vanhooteghem, Olivier ; ; Richert, Bertrand et alin Annales de Dermatologie et de Vénéréologie (2001), 128(10, Pt 1), 1063-7 Detailed reference viewed: 5 (0 ULg)Raynaud Phenomenon after Treatment of Verruca Vulgaris of the Sole with Intralesional Injection of BleomycinVanhooteghem, Olivier ; Richert, Bertrand ; de LA BRASSINNE, Michel in Pediatric Dermatology (2001), 18(3), 249-251 Intralesional injection of bleomycin (BLM) for the treatment of warts resistant to all conventional therapies is of certain interest because of the drug's low toxicity and its efficacy. However, delayed ... [more ▼] Intralesional injection of bleomycin (BLM) for the treatment of warts resistant to all conventional therapies is of certain interest because of the drug's low toxicity and its efficacy. However, delayed side effects may appear, particularly Raynaud phenomenon. Accordingly, some precautions must be taken in patients with vascular or collagen diseases and, as a precaution, pregnant or lactating women and infants should not be treated with this drug. [less ▲] Detailed reference viewed: 17 (0 ULg)Subungual abscess: a new ungual side-effect related to docetaxel therapyVanhooteghem, Olivier ; Richert, Bertrand ; et alin British Journal of Dermatology (2000), 143(2), 462-464 Detailed reference viewed: 5 (0 ULg)Une tâche pigmentée suspecteVanhooteghem, Olivier ; Richert, Bertrand ; de LA BRASSINNE, Michel in Revue de Médecine Générale [=RMG] (1999), 166 What is your diagnosis for this periungual coloured spot of the thumb ? Detailed reference viewed: 20 (0 ULg)Un orteil douloureuxVanhooteghem, Olivier ; Richert, Bertrand ; de LA BRASSINNE, Michel in Revue de Médecine Générale [=RMG] (1999), 16 Case story of a patient with a painfull sub-ungueal tumentia. Detailed reference viewed: 42 (0 ULg) |
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