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See detailInternal encoding style and schizotypy: towards a conceptually-driven account of positive symptoms
Belayachi, Sanaa ULg; Laloyaux, Julien ULg; Laroi, Frank ULg et al

in Journal of Personality Disorders (in press)

Perception results from a combination of actual data and interpretative schemata based on pre-existing knowledge. Thus, ensuing subjective experience depends on the dynamic interplay between data-driven ... [more ▼]

Perception results from a combination of actual data and interpretative schemata based on pre-existing knowledge. Thus, ensuing subjective experience depends on the dynamic interplay between data-driven and conceptually-driven processing. A chronic imbalance between these two sources of stimulus encoding is likely to be maladaptive and could underlie cognitive and behavioral disturbances similar to that observed in schizotypy, especially if the balance is tipped too far towards conceptually-driven processing (i.e., Internal encoding style). This study aimed to examine the relationships between encoding style and various dimensions of schizotypy, by using a questionnaire that evaluates the extent to which pre-existing schemata (versus cues from the outside world) affect encoding processes. Consistent with previous findings, our results revealed that both Cognitive-Perceptual and Disorganization dimensions were related to an internal mode of encoding, suggesting that individuals with these features may be characterized by a disposition to biases at early stages of encoding. [less ▲]

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See detailVers une approche intégrée de l'évaluation et de l'intervention psychologiques
Van der Linden, Martial ULg

Scientific conference (2014, October 17)

Dans cette présentation, nous défendrons une démarche d’évaluation clinique qui favorise la formulation d’une interprétation psychologique individualisée, prenant en compte la co-occurrence de difficultés ... [more ▼]

Dans cette présentation, nous défendrons une démarche d’évaluation clinique qui favorise la formulation d’une interprétation psychologique individualisée, prenant en compte la co-occurrence de difficultés psychologiques différentes, le caractère plurifactoriel de ces difficultés et l’hétérogénéité des mécanismes psychologiques qui les sous-tendent. Cette démarche d’évaluation implique d’examiner différents types de processus psychologiques (cognitifs, affectifs, motivationnels, relationnels, identitaires) et d’intégrer leur contribution respective dans une interprétation psychologique cohérente, conduisant en outre à l’identification du rôle des facteurs sociaux, situationnels et biologiques. Dans ce contexte, l’intervention psychologique devrait être taillée sur mesure en fonction des dysfonctionnements psychologiques spécifiques de la personne et devrait comporter plusieurs facettes d’intervention complémentaires, focalisées sur différents processus psychologiques. Nous illustrerons cette approche de l’évaluation et de l’intervention dans différents domaines des difficultés psychologiques (symptômes dépressifs, apathie chez les personnes âgées, insertion sociale chez les personnes ayant reçu un diagnostic de schizophrénie, difficultés de couple). [less ▲]

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See detailPerformance on a Computerized Shopping Task in Bipolar Disorder and Alcohol Dependency
Laloyaux, Julien ULg; Michel, Céline; Pellegrini, Nadia et al

Poster (2014, August 10)

Persons diagnosed with bipolar disorder and alcohol dependency are frequently subject to cognitive impairments and encounter difficulties during everyday life activities. However, little is known how ... [more ▼]

Persons diagnosed with bipolar disorder and alcohol dependency are frequently subject to cognitive impairments and encounter difficulties during everyday life activities. However, little is known how these deficits interact in real life. Moreover, previous studies have primarily used questionnaires or observational methods to assess everyday life functioning, both of which contain a number of limits. In order to address some of these limits, we developed a computerized real-life activity task, in particular, a shopping task where participants are required to shop for a list of 8 grocery store items in a virtual supermarket. Twenty individuals diagnosed with alcoholic dependence and 21 patients diagnosed with bipolar disorder were compared with healthy controls (20 and 21, respectively), matched for age, sex and educational level. All participants completed the shopping task, and both clinical groups were evaluated with an extensive battery of cognitive tests (assessing executive functioning, attention, processing speed and memory), clinical scales and a measure of real world functioning. Results showed that, for both clinical groups, performance on the computerized shopping task significantly differentiated patients and healthy controls for a number of variables, especially total time to complete the shopping task. Performances on shopping task variables, in both clinical groups, were also significantly correlated with cognitive tests measuring processing speed, episodic memory, cognitive flexibility and inhibition. Finally, performances on the computerized shopping task were significantly correlated with real world functioning in both patient groups. These findings suggest that the computerized task used in the present study provides a valid indication of the level of real world functioning for these clinical populations, and therefore may be viewed as a valuable instrument in both an evaluation and remediation context. [less ▲]

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See detailThe Neurocognitive Underpinnings of Multitasking Capacities in Persons Diagnosed with Schizophrenia
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Levaux, Marie-Noëlle ULg et al

Poster (2014, August 10)

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular during multitasking activities. Multitasking refers to activities where the person has ... [more ▼]

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia, and in particular during multitasking activities. Multitasking refers to activities where the person has to: carry out and alternate between different tasks that vary in terms of priority, difficulty and duration; define the tasks’ targets; and where the person is faced with unexpected problems during the realization of these tasks (Burgess, 2000). However, the neurocognitive underpinnings of multitasking have never been explored in schizophrenia. Further, only two cognitive models exist in the literature, based on a student sample (Logie et al., 2011) and a neurological sample (Burgess et al., 2000). Both of these models suggest three primary constructs including Memory, Planning and Intent. However, there are several limitations related to the way multitasking was evaluated in these studies. We thus developed a computerized real-life activity task designed to take into account the multitasking nature of certain everyday life activities where participants are required to prepare a room for a meeting – the Computerized Meeting Preparation Task (CMPT). Using this new task, and based on previous studies (Burgess et al., 2000; Logie et al., 2011), the aim of the present study was to evaluate a new cognitive model of multitasking ability and that takes into account certain cognitive processes that are not integrated in existing models. Fifty-seven individuals diagnosed with schizophrenia and 41 matched healthy controls completed the CMPT. Participants were also evaluated with a battery of cognitive tests. The results suggest that the CMPT has a good sensitivity. Moreover, structural equation modelling confirmed the three underlying constructs of multitasking (Memory, Planning and Intent) which are underpinned by several cognitive functions and multitasking aspects. Taken together, this new cognitive model and the CMPT could be a good basis for cognitive intervention on multitasking. [less ▲]

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See detailRelations between negative symptomatology and executive measures in schizophrenia.
Laloyaux, Julien ULg; Guettafi, Yassine; Dessart, Gregory et al

Poster (2014, June 03)

Introduction: Negative symptomatology and cognitive impairments are core features of persons diagnosed with schizophrenia that have a major negative impact on everyday life functioning. Further, some ... [more ▼]

Introduction: Negative symptomatology and cognitive impairments are core features of persons diagnosed with schizophrenia that have a major negative impact on everyday life functioning. Further, some authors (Konstantakopoulos et al., 2011) have suggested that negative symptoms and executive functions might represent different manifestations of the same syndrome, but this relation remains poorly understood. Objective: The objective was to explore relations between negative symptomatology (and in particular apathy) and executive functions in persons diagnosed with schizophrenia. Method: Twenty-seven individuals diagnosed with schizophrenia were evaluated with an extensive executive battery in addition to several measures of negative symptomatology (including specific measures of apathy) and real world functioning. Results: Results revealed that apathy was significantly related to measures of initiation (i.e. verbal fluency) and everyday life functioning. Moreover, more general measures of negative symptomatology were significantly related to multitasking abilities and cognitive flexibility. Discussion: In this study, we assessed the relations between negative symptomatology and executive measures. The results confirmed the links between these constructs, thus suggesting a common neural substrate. Conclusion: Based on results from the present study, executive dysfunctions and negative symptomatology may be seen as representing different manifestations of the same syndrome. [less ▲]

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See detailMultitasking capacities in persons diagnosed with schizophrenia: A preliminary examination of their neurocognitive underpinnings and ability to predict real world functioning
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Levaux, Marie-Noëlle ULg et al

Poster (2014, April 08)

Background: Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia. Moreover, patients seem to demonstrate particular difficulties during complex and ... [more ▼]

Background: Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia. Moreover, patients seem to demonstrate particular difficulties during complex and multitasking activities, such as cooking a meal (Semkovska et al., 2004). Multitasking refers to activities where the person has to: carry out and alternate between different tasks that vary in terms of priority, difficulty and duration; define the tasks’ targets; and where the person is faced with unexpected problems during the realization of these tasks (Burgess, 2000). However, at present, patients’ multitasking capacities have not been adequately examined in the literature due to an absence of suitable assessment strategies. We thus recently developed a computerized real-life activity task designed to take into account the complex and multitasking nature of certain everyday life activities where participants are required to prepare a room for a meeting – the Computerized Meeting Preparation Task (CMPT) Methods: Twenty-one individuals diagnosed with schizophrenia and 20 matched healthy controls completed the CMPT. During the CMPT, participants found themselves in a virtual room that they had to prepare for a meeting while respecting a list of instructions (the placement of the guests, the needed objects, the desired drinks, etc.). Patients were also evaluated with an extensive cognitive battery (assessing executive functions, attention, processing speed and memory), measures of symptomatology and real world functioning. To examine the ecological validity of the CMPT, 14 others patients were recruited and were given the computerized version and a real version of the meeting preparation task. Results: Results demonstrated that performance on the CMPT significantly differentiated patients and healthy controls for the total time to complete task, planning efficiency, and the respect of the instructions. Moreover, these variables were significantly correlated with executive functioning (i.e. cognitive flexibility and planning), suggesting the major implication of these cognitive processes in multitasking activities. Performance on the CMPT also significantly predicted up to 50% of real world functioning. Finally, performances on the computerized version and the real version of the meeting preparation task were highly correlated, suggesting good ecological validity. Discussion: In this study, we created a novel task involving the multitasking nature of real world activities. The results demonstrated that this approach provides a good indication of the real world functioning in patients diagnosed with schizophrenia. Moreover, results suggest a particular implication of executive functioning in multitasking activities. These findings suggest the importance of evaluating multitasking capacities in patients diagnosed with schizophrenia in order to predict real world functioning. [less ▲]

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See detailMultitasking capacities in persons diagnosed with schizophrenia: A preliminary examination of their neurocognitive underpinnings and ability to predict real world functioning
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Levaux, Marie-Noëlle ULg et al

in Schizophrenia Research (2014, April), 153(Supl. 1), 344

Background: Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia. Moreover, patients seem to demonstrate particular difficulties during complex and ... [more ▼]

Background: Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia. Moreover, patients seem to demonstrate particular difficulties during complex and multitasking activities, such as cooking a meal (Semkovska et al., 2004). Multitasking refers to activities where the person has to: carry out and alternate between different tasks that vary in terms of priority, difficulty and duration; define the tasks’ targets; and where the person is faced with unexpected problems during the realization of these tasks (Burgess, 2000). However, at present, patients’ multitasking capacities have not been adequately examined in the literature due to an absence of suitable assessment strategies. We thus recently developed a computerized real-life activity task designed to take into account the complex and multitasking nature of certain everyday life activities where participants are required to prepare a room for a meeting – the Computerized Meeting Preparation Task (CMPT) Methods: Twenty-one individuals diagnosed with schizophrenia and 20 matched healthy controls completed the CMPT. During the CMPT, participants found themselves in a virtual room that they had to prepare for a meeting while respecting a list of instructions (the placement of the guests, the needed objects, the desired drinks, etc.). Patients were also evaluated with an extensive cognitive battery (assessing executive functions, attention, processing speed and memory), measures of symptomatology and real world functioning. To examine the ecological validity of the CMPT, 14 others patients were recruited and were given the computerized version and a real version of the meeting preparation task. Results: Results demonstrated that performance on the CMPT significantly differentiated patients and healthy controls for the total time to complete task, planning efficiency, and the respect of the instructions. Moreover, these variables were significantly correlated with executive functioning (i.e. cognitive flexibility and planning), suggesting the major implication of these cognitive processes in multitasking activities. Performance on the CMPT also significantly predicted up to 50% of real world functioning. Finally, performances on the computerized version and the real version of the meeting preparation task were highly correlated, suggesting good ecological validity. Discussion: In this study, we created a novel task involving the multitasking nature of real world activities. The results demonstrated that this approach provides a good indication of the real world functioning in patients diagnosed with schizophrenia. Moreover, results suggest a particular implication of executive functioning in multitasking activities. These findings suggest the importance of evaluating multitasking capacities in patients diagnosed with schizophrenia in order to predict real world functioning. [less ▲]

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See detailPsychometric properties of the French translation of the Behavioral Activation for Depression Scale - Short Form (BADS-SF) in non-clinical adults
Wagener, Aurélie ULg; Van der Linden, Martial ULg; Blairy, Sylvie ULg

in Comprehensive Psychiatry (2014)

A decrease in the level of engagement in activities (“behavioral activation”) is usually observed in major depressive disorder. Because behavioral treatments of depression aim to counteract that mechanism ... [more ▼]

A decrease in the level of engagement in activities (“behavioral activation”) is usually observed in major depressive disorder. Because behavioral treatments of depression aim to counteract that mechanism, assessing changes in behavioral activation during treatment is of great interest. Therefore, Manos et al. (2011) developed a scale that assesses these changes, which was called the Behavioral Activation for Depression Scale – Short Form (BADS-SF). The aim of this study is to present a French version of this scale and to discuss its psychometric properties. The BADS-SF was translated into French, and 504 non-clinical adults completed an online survey that was composed of that scale and convergent measures. Exploratory and confirmatory factor analyses were performed in two independent samples, and a two-factor solution was recommended, which references two functions of the engagement in activities (i.e., “activation” and “avoidance”). The results showed high levels of internal consistency and satisfying scores in terms of skewness and kurtosis. Moreover, relationships with measures of depression and behavioral systems indicated a good convergent validity. Therefore, the French BADS-SF can be seen as a reliable and valid instrument. [less ▲]

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See detailMultitasking capacities in persons diagnosed with schizophrenia: A preliminary examination of their neurocognitive underpinnings and ability to predict real world functioning
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Levaux, Marie-Noëlle ULg et al

in Psychiatry Research (2014), 217

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia and in particular during multitasking activities. However, at present, patients' multitasking capacities ... [more ▼]

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia and in particular during multitasking activities. However, at present, patients' multitasking capacities have not been adequately examined in the literature due to an absence of suitable assessment strategies. We thus recently developed a computerized real-life activity task designed to take into account the complex and multitasking nature of certain everyday life activities where participants are required to prepare a room for a meeting. Twenty-one individuals diagnosed with schizophrenia and 20 matched healthy controls completed the computerized task. Patients were also evaluated with a cognitive battery, measures of symptomatology and real world functioning. To examine the ecological validity, 14 other patients were recruited and were given the computerized version and a real version of the meeting preparation task. Results showed that performance on the computerized task was significantly correlated with executive functioning, pointing to the major implication of these cognitive processes in multitasking situations. Performance on the computerized task also significantly predicted up to 50% of real world functioning. Moreover, the computerized task demonstrated good ecological validity. These findings suggest the importance of evaluating multitasking capacities in patients diagnosed with schizophrenia in order to predict real world functioning. [less ▲]

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See detailMultitasking capacities in persons diagnosed with schizophrenia: A preliminary examination of their neurocognitive underpinnings and ability to predict real world functioning
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Levaux, Marie-Noëlle ULg et al

in Psychiatry Research (2014), 217

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia and in particular during multitasking activities. However, at present, patients' multitasking capacities ... [more ▼]

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia and in particular during multitasking activities. However, at present, patients' multitasking capacities have not been adequately examined in the literature due to an absence of suitable assessment strategies. We thus recently developed a computerized real-life activity task designed to take into account the complex and multitasking nature of certain everyday life activities where participants are required to prepare a room for a meeting. Twenty-one individuals diagnosed with schizophrenia and 20 matched healthy controls completed the computerized task. Patients were also evaluated with a cognitive battery, measures of symptomatology and real world functioning. To examine the ecological validity, 14 other patients were recruited and were given the computerized version and a real version of the meeting preparation task. Results showed that performance on the computerized task was significantly correlated with executive functioning, pointing to the major implication of these cognitive processes in multitasking situations. Performance on the computerized task also significantly predicted up to 50% of real world functioning. Moreover, the computerized task demonstrated good ecological validity. These findings suggest the importance of evaluating multitasking capacities in patients diagnosed with schizophrenia in order to predict real world functioning. [less ▲]

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See detailMultitasking capacities in persons diagnosed with schizophrenia: A preliminary examination of their neurocognitive underpinnings and ability to predict real world functioning
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Levaux, Marie-Noëlle ULg et al

in Psychiatry Research (2014), 217

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia and in particular during multitasking activities. However, at present, patients' multitasking capacities ... [more ▼]

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia and in particular during multitasking activities. However, at present, patients' multitasking capacities have not been adequately examined in the literature due to an absence of suitable assessment strategies. We thus recently developed a computerized real-life activity task designed to take into account the complex and multitasking nature of certain everyday life activities where participants are required to prepare a room for a meeting. Twenty-one individuals diagnosed with schizophrenia and 20 matched healthy controls completed the computerized task. Patients were also evaluated with a cognitive battery, measures of symptomatology and real world functioning. To examine the ecological validity, 14 other patients were recruited and were given the computerized version and a real version of the meeting preparation task. Results showed that performance on the computerized task was significantly correlated with executive functioning, pointing to the major implication of these cognitive processes in multitasking situations. Performance on the computerized task also significantly predicted up to 50% of real world functioning. Moreover, the computerized task demonstrated good ecological validity. These findings suggest the importance of evaluating multitasking capacities in patients diagnosed with schizophrenia in order to predict real world functioning. [less ▲]

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See detailMultitasking capacities in persons diagnosed with schizophrenia: A preliminary examination of their neurocognitive underpinnings and ability to predict real world functioning
Laloyaux, Julien ULg; Van der Linden, Martial ULg; Levaux, Marie-Noëlle ULg et al

in Psychiatry Research (2014), 217

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia and in particular during multitasking activities. However, at present, patients' multitasking capacities ... [more ▼]

Difficulties in everyday life activities are core features of persons diagnosed with schizophrenia and in particular during multitasking activities. However, at present, patients' multitasking capacities have not been adequately examined in the literature due to an absence of suitable assessment strategies. We thus recently developed a computerized real-life activity task designed to take into account the complex and multitasking nature of certain everyday life activities where participants are required to prepare a room for a meeting. Twenty-one individuals diagnosed with schizophrenia and 20 matched healthy controls completed the computerized task. Patients were also evaluated with a cognitive battery, measures of symptomatology and real world functioning. To examine the ecological validity, 14 other patients were recruited and were given the computerized version and a real version of the meeting preparation task. Results showed that performance on the computerized task was significantly correlated with executive functioning, pointing to the major implication of these cognitive processes in multitasking situations. Performance on the computerized task also significantly predicted up to 50% of real world functioning. Moreover, the computerized task demonstrated good ecological validity. These findings suggest the importance of evaluating multitasking capacities in patients diagnosed with schizophrenia in order to predict real world functioning. [less ▲]

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See detailBrains creating stories of selves: the neural basis of autobiographical reasoning.
D'Argembeau, Arnaud ULg; Cassol, Helena; Phillips, Christophe ULg et al

in Social Cognitive and Affective Neuroscience (2014), 9

Personal identity critically depends on the creation of stories about the self and one's life. The present study investigates the neural substrates of autobiographical reasoning, a process central to the ... [more ▼]

Personal identity critically depends on the creation of stories about the self and one's life. The present study investigates the neural substrates of autobiographical reasoning, a process central to the construction of such narratives. During fMRI scanning, participants approached a set of personally significant memories in two different ways: on some trials, they remembered the concrete content of the events (autobiographical remembering), whereas on other trials they reflected on the broader meaning and implications of their memories (autobiographical reasoning). Relative to remembering, autobiographical reasoning recruited a left-lateralized network involved in conceptual processing (including the dorsal medial prefrontal cortex (MPFC), inferior frontal gyrus, middle temporal gyrus, and angular gyrus). The ventral MPFC-an area that may function to generate personal/affective meaning-was not consistently engaged during autobiographical reasoning across participants but, interestingly, the activity of this region was modulated by individual differences in interest and willingness to engage in self-reflection. These findings support the notion that autobiographical reasoning and the construction of personal narratives go beyond mere remembering in that they require deriving meaning and value from past experiences. [less ▲]

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See detailIndividual differences in cognitive representations of action influence the activation of goal concepts
Belayachi, Sanaa ULg; Van der Linden, Martial ULg

in Acta Psychologica (2013), 142(2), 259-264

Goal representations play a key role in various psychological processes, including behavioral regulation, self-perception and social understanding. Research on cognitive representations of action has ... [more ▼]

Goal representations play a key role in various psychological processes, including behavioral regulation, self-perception and social understanding. Research on cognitive representations of action has identified individual differences in the general tendency to construe actions in terms of their goal (vs. movement parameters), which can be reliably assessed with the Behavior Identification Form (BIF). The aim of the present study was to examine how individual differences in action identification, as measured by the BIF, affect online processing of action in a laboratory study. The main results showed that the level of action identification predicted participants' performance in a task designed to implicitly assess people's automatic processing of action regarding goal features. We discussed the possible role of impaired goal processing in psychological dysfunctions. [less ▲]

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See detailPerformance on a computerized shopping task significantly predicts real world functioning in persons diagnosed with bipolar disorder.
Laloyaux, Julien ULg; Pellegrini, Nadia; Mourad, Haitham et al

in Psychiatry Research (2013), 210(2), 465-471

Persons diagnosed with bipolar disorder often suffer from cognitive impairments. However, little is known concerning how these cognitive deficits impact their real world functioning. We developed a ... [more ▼]

Persons diagnosed with bipolar disorder often suffer from cognitive impairments. However, little is known concerning how these cognitive deficits impact their real world functioning. We developed a computerized real-life activity task, where participants are required to shop for a list of grocery store items. Twenty one individuals diagnosed with bipolar disorder and 21 matched healthy controls were administered the computerized shopping task. Moreover, the patient group was assessed with a battery of cognitive tests and clinical scales. Performance on the shopping task significantly differentiated patients and healthy controls for two variables: Total time to complete the shopping task and Mean time spent to consult the shopping list. Moreover, in the patient group, performance on these variables from the shopping task correlated significantly with cognitive functioning (i.e. processing speed, verbal episodic memory, planning, cognitive flexibility, and inhibition) and with clinical variables including duration of illness and real world functioning. Finally, variables from the shopping task were found to significantly explain 41% of real world functioning of patients diagnosed with bipolar disorder. These findings suggest that the shopping task provides a good indication of real world functioning and cognitive functioning of persons diagnosed with bipolar disorder. [less ▲]

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See detailMemory disorders in children
Majerus, Steve ULg; Van der Linden, Martial ULg

in Handbook of Clinical Neurology (2013), 111

Memory disorders are a frequent consequence of a variety of childhood neurological conditions. We will review the characteristics of memory disorders as a function of the main four memory systems: short ... [more ▼]

Memory disorders are a frequent consequence of a variety of childhood neurological conditions. We will review the characteristics of memory disorders as a function of the main four memory systems: short-term memory, episodic memory, semantic memory, and procedural memory. For each system, we will identify the most typical cerebral and/or genetic correlates, and we will discuss the impact of impairment of each memory system on everyday life functioning. © 2013 Elsevier B.V. [less ▲]

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See detailFactorial structure and psychometric properties of the French adaptation of the Dissociative Experiences Scale (DES) in non-clinical participants
Laroi, Frank ULg; Billieux, J; Defeldre, A-C et al

in European Review of Applied Psychology = Revue Européenne de Psychologie Appliquée (2013), 63

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