References of "Van Wouwe, Nathalie"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailValidation and interpretation of CALUX as a tool for the estimation of dioxin-like activity in marine biological matrixes.
Windal, Isabelle; Van Wouwe, Nathalie; Eppe, Gauthier ULg et al

in Environmental Science & Technology (2005), 39(6), 1741-1748

Among the different analytical tools proposed as an alternative to the very expensive gas chromatography high-resolution mass spectrometry (GC-HRMS) analyses of polychlorodibenzo-p-dioxin and ... [more ▼]

Among the different analytical tools proposed as an alternative to the very expensive gas chromatography high-resolution mass spectrometry (GC-HRMS) analyses of polychlorodibenzo-p-dioxin and polychlorodibenzofurans, Chemically Activated LUciferase gene eXpression (CALUX) in vitro cell bioassay is very promising. It allows the analyses of a high number of samples since it is relatively fast, inexpensive, and sensitive. However, this technique is not yet widely applied for screening or environmental monitoring. The main reasons are probably the lack of validation and the difficulty in interpreting the global biological response of the bioassay. In this paper, the strict quality control criteria set up for the validation of CALUX are described. The validation has shown good repeatability (relative standard deviation (RSD) = 9%) and good within-lab reproducibility (RSD = 15%) of the results. The quantification limit, in the conditions applied in this paper, is 1.25 pg CALUX-TEQ/g fat. Comparison of CALUX and GC-HRMS analysis was made for various marine matrixes (fishes, mussels, starfishes, sea birds, and marine mammals). Good correlations are usually observed, but there are systematic differences between the results. Attempts are made to identify the origin of the discrepancy between the two methods. [less ▲]

Detailed reference viewed: 32 (1 ULg)
Full Text
Peer Reviewed
See detailFactors influencing the PCDD/F levels in plasma of Belgian blood donors
Debacker, Neomi; Van Wouwe, Nathalie; Sasse, André et al

in Organohalogen Compounds (2005)

Detailed reference viewed: 16 (0 ULg)
Full Text
Peer Reviewed
See detailLevels of contamination for various pollutants present in Belgian human plasma
Van Wouwe, Nathalie; Covaci, Adrian; Kannan, Kurunthachalam et al

in Organohalogen Compounds (2004)

Detailed reference viewed: 31 (9 ULg)
Full Text
Peer Reviewed
See detailDIOXIN BODY BURDEN AMONG BLOOD DONORS BEFORE AND AFTER THE BELGIAN DIOXIN/PCB INCIDENT
Debacker, Noemi; Sasse, André; Van Wouwe, Nathalie et al

in Organohalogen Compounds (2004)

Detailed reference viewed: 24 (0 ULg)
Full Text
Peer Reviewed
See detailApplication of the CALUX bioassay for epidemiological study: analyses of Belgian human plasma
Van Wouwe, Nathalie; Debacker, Noemi; Sasse, André et al

in Organohalogen Compounds (2004)

Detailed reference viewed: 18 (0 ULg)
Full Text
Peer Reviewed
See detailValidation and discussion of CALUX analysis for marine samples
Windal, Isabelle; Van Wouwe, Nathalie; Carbonnelle, Sophie et al

in Organohalogen Compounds (2003)

Detailed reference viewed: 22 (2 ULg)
Full Text
Peer Reviewed
See detailAnalysis of PCDD/Fs in human blood plasma using CALUX bioassay and GC-HRMS: a comparison
Van Wouwe, Nathalie; Eppe, Gauthier ULg; Xhrouet, Céline ULg et al

in Organohalogen Compounds (2003)

Detailed reference viewed: 15 (1 ULg)