References of "Van Houtte, P"
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See detailShort course chemotherapy followed by concomitant chemoradiotherapy and surgery in locally advanced rectal cancer: a randomized multicentric phase II study.
Marechal, R.; Vos, B.; POLUS, Marc ULg et al

in Annals of Oncology (2012), 23(6), 1525-30

BACKGROUND: Induction chemotherapy has been suggested to impact on preoperative chemoradiation efficacy in locally advanced rectal cancer (LARC). To evaluate in LARC patients, the feasibility and efficacy ... [more ▼]

BACKGROUND: Induction chemotherapy has been suggested to impact on preoperative chemoradiation efficacy in locally advanced rectal cancer (LARC). To evaluate in LARC patients, the feasibility and efficacy of a short intense course of induction oxaliplatin before preoperative chemoradiotherapy (CRT). PATIENTS AND METHODS: Patients with T2-T4/N+ rectal adenocarcinoma were randomly assigned to arm A-preoperative CRT with 5-fluorouracil (5-FU) continuous infusion followed by surgery-or arm B-induction oxaliplatin, folinic acid and 5-FU followed by CRT and surgery. The primary end point was the rate of ypT0-1N0 stage achievement. RESULTS: Fifty seven patients were randomly assigned (arm A/B: 29/28) and evaluated for planned interim analysis. On an intention-to-treat basis, the ypT0-1N0 rate for arms A and B were 34.5% (95% CI: 17.2% to 51.8%) and 32.1% (95% CI: 14.8% to 49.4%), respectively, and the study therefore was closed prematurely for futility. There were no statistically significant differences in other end points including pathological complete response, tumor regression and sphincter preservation. Completion of the preoperative CRT sequence was similar in both groups. Grade 3/4 toxicity was significantly higher in arm B. CONCLUSIONS: Short intense induction oxaliplatin is feasible in LARC patients without compromising the preoperative CRT completion, although the current analysis does not indicate increased locoregional impact on standard therapy. [less ▲]

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See detailForming forces in single point incremental forming: prediction by finite element simulations, validation and sensitivity
Henrard, Christophe; Bouffioux, Chantal ULg; Eyckens, P. et al

in Computational Mechanics (2011), 47

The aim of this article is to study the accuracy of finite element simulations in predicting the tool force occurring during the single point incremental forming (SPIF) process. The forming of two cones ... [more ▼]

The aim of this article is to study the accuracy of finite element simulations in predicting the tool force occurring during the single point incremental forming (SPIF) process. The forming of two cones in soft aluminum was studied with two finite element (FE) codes and several constitutive laws (an elastic–plastic law coupled with various hardening models). The parameters of these laws were identified using several combinations of a tensile test, shear tests, and an inverse modeling approach taking into account a test similar to the incremental forming process. Comparisons between measured and predicted force values are performed. This article shows that three factors have an influence on force prediction: the type of finite element, the constitutive law and the identification procedure for the material parameters. In addition, it confirms that a detailed description of the behavior occurring across the thickness of the metal sheet is crucial for an accurate force prediction by FE simulations, even though a simple analytical formula could provide an otherwise acceptable answer. [less ▲]

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See detailStrain Evolution in the Single Point Incremental Forming Process: Digital Image Correlation Measurement and Finite Element Prediction
Eyckens, P.; Belkassem, B.; Henrard, Christophe et al

in International Journal of Material Forming (2011)

Incremental Sheet Forming (ISF) is a relatively new class of sheet forming processes that allow the manufacture of complex geometries based on computer-controlled forming tools in replacement (at least ... [more ▼]

Incremental Sheet Forming (ISF) is a relatively new class of sheet forming processes that allow the manufacture of complex geometries based on computer-controlled forming tools in replacement (at least partially) of dedicated tooling. This paper studies the straining behaviour in the Single Point Incremental Forming (SPIF) variant (in which no dedicated tooling at all is required), both on experimental basis using Digital Image Correlation (DIC) and on numerical basis by the Finite Element (FE) method. The aim of the paper is to increase understanding of the deformation mechanisms inherent to SPIF, which is an important issue for the understanding of the high formability observed in this process and also for future strategies to improve the geometrical accuracy. Two distinct large-strain FE formulations, based on shell and first-order reduced integration brick elements, are used to model the sheet during the SPIF processing into the form of a truncated cone. The prediction of the surface strains on the outer surface of the cone is compared to experimentally obtained strains using the DIC technique. It is emphasised that the strain history as calculated from the DIC displacement field depends on the scale of the strain definition. On the modelling side, it is shown that the mesh density in the FE models plays a similar role on the surface strain predictions. A good qualitative agreement has been obtained for the surface strain components. One significant exception has however been found, which concerns the circumferential strain evolution directly under the forming tool. The qualitative discrepancy is explained through a mechanism of through-thickness shear in the experiment, which is not fully captured by the present FE modelling since it shows a bending-dominant accommodation mechanism. The effect of different material constitutive behaviours on strain prediction has also been investigated, the parameters of which were determined by inverse modelling using a specially designed sheet forming test. Isotropic and anisotropic yield criteria are considered, combined with either isotropic or kinematic hardening. The adopted constitutive law has only a limited influence on the surface strains. Finally, the experimental surface strain evolution is compared between two cones with different forming parameters. It is concluded that the way the plastic zone under the forming tool accommodates the moving tool (i.e. by through-thickness shear or rather by bending) depends on the process parameters. The identification of the most determining forming parameter that controls the relative importance of either mechanism is an interesting topic for future research. [less ▲]

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See detailBiased symptoms attribution and radiation therapy for breast cancer: prevalence, changes over time and impact on distress
Bonamis, O.; Liénard, A.; Merckaert, I. et al

in Psycho-oncology (2010, May), 19(Suppl.2)(1-313), 133

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See detailForming Forces in Single Point Incremental Forming, Prediction by Finite Element Simulations
Henrard, Christophe; Bouffioux, Chantal ULg; Eyckens, P. et al

in Computational Mechanics (2010)

The aim of this article is to study the accuracy of the nite element simulations to predict the tool force during the Single Point Incremental Forming process. The forming of two cones in soft aluminum ... [more ▼]

The aim of this article is to study the accuracy of the nite element simulations to predict the tool force during the Single Point Incremental Forming process. The forming of two cones in soft aluminum was studied with two Finite Element (FE) codes and several constitutive laws (an elastic-plastic model coupled with different hardening approaches). The parameters of these laws were identi ed using tensile and shear tests, as well as an inverse approach taking into account a test similar to the incremental forming process. Comparisons between measured and predicted force values are performed. This article shows that three factors have an in uence on the force prediction: the type of nite element, the constitutive law and the identi cation procedure for the material parameters. In addition, it con rms that a very detailed description of the behavior occurring across the thickness of the metal sheet is crucial for an accurate force prediction by FE simulations, even though a simple analytical formula could provide an otherwise acceptable answer. [less ▲]

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See detailSymptom attribution and radiation thérapy for breast cancer : changes over time and associated psychological factors
Bonamis, O.; Liénard, A.; Coucke, Philippe ULg et al

in Psycho-oncology (2009, June), 18 (Suppl. 2)

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See detailForming limit predictions for single-point incremental sheet metal forming
Van Bael, A.; Eyckens, P.; He, S. et al

in Cueto, Elías; Chinesta, Francisco (Eds.) Proceedings of the 10th International ESAFORM Conference on Material Forming (2007)

A characteristic of incremental sheet metal forming is that much higher deformations can be achieved than conventional forming limits. In this paper it is investigated to which extent the highly non ... [more ▼]

A characteristic of incremental sheet metal forming is that much higher deformations can be achieved than conventional forming limits. In this paper it is investigated to which extent the highly non-monotonic strain paths during such a process may be responsible for this high formability. A Marciniak-Kuczynski (MK) model is used to predict the onset of necking of a sheet subjected to the strain paths obtained by finite-element simulations. The predicted forming limits are considerably higher than for monotonic loading, but still lower than the experimental ones. This discrepancy is attributed to the strain gradient over the sheet thickness, which is not taken into account in the currently used MK model. [less ▲]

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See detailAn FEM-aided investigation of the deformation during single point incremental forming
He, S.; Van Bael, A.; Van Houtte, P. et al

in Modelling & Simulation in Materials Science & Engineering (2006)

Incremental forming is an innovative and flexible sheet metal forming technology for small batch production and prototyping, which does not require any dedicated die or punch to form a complex shape. This ... [more ▼]

Incremental forming is an innovative and flexible sheet metal forming technology for small batch production and prototyping, which does not require any dedicated die or punch to form a complex shape. This paper investigates the process of single point incremental forming of an aluminium cone both experimentally and numerically. Finite element models are established to simulate the process. The output of the simulation is given in terms of final geometry, the thickness profile of the product and the strain history and distribution during the deformation. Comparison between the simulation results and the experimental data is made. [less ▲]

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See detailEffect of FEM choices in the modelling of incremental forming of aluminium sheets
He, S.; Van Bael, A.; Van Houtte, P. et al

in Banabic, D. (Ed.) Proceedings of the 8th ESAFORM Conference on Material Forming (2005)

This paper investigates the process of single point incremental forming of an aluminium cone with a 50-degree wall angle. Finite element (FE) models are established to simulate the process. Different FE ... [more ▼]

This paper investigates the process of single point incremental forming of an aluminium cone with a 50-degree wall angle. Finite element (FE) models are established to simulate the process. Different FE packages have been used. Various aspects associated with the numerical choices as well as the material and process parameters have been studied. The final geometry and the reaction forces are presented as the results of the simulations. Comparison between the simulation results and the experimental data is also made. [less ▲]

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See detailAxes rotation during simple shear test: Measurement and predictions
Lelotte, Thomas; Gerday, Anne-Françoise ULg; Flores, Paulo et al

in Oñate, E.; Owen, D. R. J. (Eds.) Proceedings of the VIII International Conference on Computational Plasticity (COMPLAS VIII) (2005)

For a simple shear test, the finite element (FE) local frame, that stays orthogonal, does not follow the anisotropic material frame. To study this effect, FE simulations have been compared with ... [more ▼]

For a simple shear test, the finite element (FE) local frame, that stays orthogonal, does not follow the anisotropic material frame. To study this effect, FE simulations have been compared with experimental results (optical and texture measurements) and it was shown that it is necessary to take into account the effect of texture updating for local axes rotation. [less ▲]

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See detailFinite element modeling of incremental forming of aluminium sheets
He, S.; Van Bael, A.; Van Houtte, P. et al

in Advanced Materials Research (2005), 6/8

Incremental forming is an innovative and flexible sheet metal forming technology for small batch production and prototyping, which does not require any dedicated die or punch to form a complex shape. This ... [more ▼]

Incremental forming is an innovative and flexible sheet metal forming technology for small batch production and prototyping, which does not require any dedicated die or punch to form a complex shape. This paper investigates the process of single point incremental forming of an aluminum cone with a 50-degree wall angle both experimentally and numerically. Finite element models are established to simulate the process. The output of the simulation is given in terms of final geometry, the thickness distribution of the product, the strain history and distribution during the deformation as well as the reaction forces. Comparison between the simulation results and the experimental data is made. [less ▲]

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See detailComparison of FEM simulations for the incremental forming process
Henrard, Christophe ULg; Habraken, Anne ULg; Szekeres, A. et al

in Advanced Materials Research (2005), 6-8

Incremental forming is an innovative and highly flexible sheet metal forming technology for small batch production and prototyping that does not require any adapted dies or punches to form a complex shape ... [more ▼]

Incremental forming is an innovative and highly flexible sheet metal forming technology for small batch production and prototyping that does not require any adapted dies or punches to form a complex shape. The purpose of this article is to perform FEM simulations of the forming of a cone with a 50-degree wall angle by incremental forming and to investigate the influence of some crucial computational parameters on the simulation. The influence of several parameters will be discussed: the FEM code used (Abaqus or Lagamine, a code developed at the University of Liège), the mesh size, the potential simplification due to the symmetry of the part and the friction coefficient. The output is given in terms of final geometry (which depends on the springback), strain history and distribution during the deformation, as well as reaction forces. It will be shown that the deformation is localized around the tool and that the deformations constantly remain close to a plane strain state for this geometry. Moreover, the tool reaction clearly depends on the way the contact is taken into account. [less ▲]

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See detailFinite-element simulations of cup drawing using the taylor and the lamel model
Van Bael, A.; He, S.; Van Houtte, P. et al

in Stören, Sigurd (Ed.) Proceedings of the 7th ESAFORM conference on Materials Forming (2004)

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See detailPrognostic factors in urothelial renal pelvis and ureter tumors: A multicenter Rare Cancer Network study
Ozsahin, Mahmut; Zouhair, Abderrahim; Villà, S. et al

in International Journal of Radiation, Oncology, Biology, Physics (1997), 3(2(supp)), 290

Detailed reference viewed: 5 (2 ULg)