References of "Van Hees, Thierry"
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See detailPharmacists' role in handling problems with prescriptions for atithrombotic medication in Belgian community pharmacies
Desmaele; De Wulf, I; Dupont, AG et al

in International Journal of Clinical Pharmacy [=IJCP] (2015), 37(4), 656-668

Background Community pharmacists have an important task in the follow-up of patients treated with antithrombotics. When delivering these medicines, pharmacists can encounter drug–related problems (DRPs ... [more ▼]

Background Community pharmacists have an important task in the follow-up of patients treated with antithrombotics. When delivering these medicines, pharmacists can encounter drug–related problems (DRPs) with substantial clinical and economic impact. Objective To investigate the amount and type of antithrombotic related DRPs as well as how community pharmacists handled these DRPs. Setting Belgian community pharmacies. Methods MSc pharmacy students of six Belgian universities collected data about all DRPs encountered by a pharmacist during ten half days of their pharmacy internship. Data were registered about DRPs detected at delivery and in an a posteriori setting, when consulting the medical history of the patient. Classification of the DRP, cause of the DRP, intervention and result of the intervention were registered. Main outcome measure Amount and type of antotrombitocs related DRPs occurring in community pharmacies, as well as how community pharmacists handled these DRPs. Results 3.1 % of the 15,952 registered DRPs concerned antithrombotics. 79.3 % of these DRPs were detected at delivery and 20.7 % were detected a posteriori. Most antithrombotic-related DRPs concerned problems with the choice of the drug (mainly because of drug–drug interactions) or concerned logistic problems. Almost 80 % of the antithrombotic-related DRPs were followed by an intervention of the pharmacist, mainly at the patient’s level, resulting in 90.1 % of these DRPs partially or totally solved. Conclusion Different DRPs with antithrombotic medication occurred in Belgian community pharmacies. About 20 % was detected in an a posteriori setting, showing the benefit of medication review. Many of the encountered DRPs were of technical nature (60.7 %). These DRPs were time-consuming for the pharmacist to resolve and should be prevented. Most of the DRPs could be solved, demonstrating the added value of the community pharmacist as first line healthcare provider. [less ▲]

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See detailLes génériques d’antibiotiques : une fausse bonne idée ?
Van Hees, Thierry ULg

Scientific conference (2015, March 10)

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See detailPrésentation d'un nouvea&u site de données probantes pharmaceutiques
Guérin, A; Spinewine, A; Van Hees, Thierry ULg et al

in Journal de Pharmacie de Belgique (2015), 1

Conscient des choix difficiles auxquels les décideurs de la santé sont confrontés et de la volonté de développer les soins pharmaceutiques, l’équipe de l’Unité de recherche en pratique pharmaceutique du ... [more ▼]

Conscient des choix difficiles auxquels les décideurs de la santé sont confrontés et de la volonté de développer les soins pharmaceutiques, l’équipe de l’Unité de recherche en pratique pharmaceutique du CHU Sainte-Justine s’est intéressée aux preuves décrivant le rôle et les retombées des activités du pharmacien. Ce projet de recherche a pris la forme d’une démarche structurée de revue et d’analyse documentaire des preuves disponibles. Un site Internet a été développé et programmé afin d’assurer efficacement le partage des connaissances (http://impactpharmacie. org). Le site Impact Pharmacie recense les preuves du rôle et des retombées de l’activité pharmaceutique, tant en milieu hospitalier qu’en milieu ambulatoire. Ce site recense notamment douze articles issus de la littérature pharmaceutique belge ayant trait à la pratique hospitalière et communautaire. On recense quatre indicateurs de résultats avec des retombées positives (i.e. statistiquement significatives) des interventions pharmaceutiques. Ce site peut contribuer à alimenter la réflexion et les actions entourant le développement de la pharmacie clinique en Belgique. [less ▲]

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See detailPerception de la pharmacovigilance par les futurs pharmaciens hospitaliers belges, français, québécois et suisses
Cerruti, L; Lebel, D; Van Hees, Thierry ULg et al

in Journal of Population Therapeutics and Clinical Pharmacology (2014, September 17), 21(2), 320

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See detailSelf-medication in persistent rhinitis: overuse of decongestants in half of the patients.
Mehuys, Els; Gevaert, Philippe; Brusselle, Guy et al

in Journal of Allergy and Clinical Immunology - In Practice (2014), 2(3), 313-319

BACKGROUND: Patients with rhinitis often self-medicate with over-the-counter drugs, however this self-treating population has remained largely unstudied. OBJECTIVE: To characterize individuals self ... [more ▼]

BACKGROUND: Patients with rhinitis often self-medicate with over-the-counter drugs, however this self-treating population has remained largely unstudied. OBJECTIVE: To characterize individuals self-medicating persistent rhinitis and to determine the prevalence of and risk factors for intranasal decongestant overuse within this population. METHODS: A cross-sectional observational study of individuals self-medicating persistent rhinitis (defined according to the Allergic Rhinitis and its Impact on Asthma guidelines). Participants (n = 895) completed a self-administered questionnaire to assess current symptoms, rhinitis medication, and previous physician diagnosis. Intranasal decongestant overuse was defined as daily use for at least 1 year. RESULTS: The vast majority of subjects (95%) had moderate-to-severe rhinitis. Nasal congestion was the predominant symptom (median visual analog scale, 6.6 cm; interquartile range, 3.4 cm). Sixty-five percent had had their current nasal problems for more than 5 years. Approximately 80% had a physician diagnosis (mainly allergic rhinitis or rhinosinusitis). The prevalence of intranasal decongestant overuse was high (49%), despite the fact that most of the patients (80%) were educated about the limit on duration of use. Use of intranasal glucocorticosteroids was inversely related to being an overuser (odds ratio 0.24 [95% CI, 0.17-0.35]). The risk of intranasal decongestant overuse also was reduced by use of other medications (oral H1 antihistamines and decongestants), use of nasal saline solution, and more symptoms of itchy and/or runny eyes or colored mucus. Risk was increased by a more severely blocked nose, longer duration of symptoms, the presence of sleep disturbance, higher body mass index, and previous advice to limit the duration of intranasal decongestant use. CONCLUSION: Half of the individuals self-medicating persistent rhinitis overused intranasal decongestants, despite the fact that they were educated about the limit on duration of use. [less ▲]

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See detailZelfbehandeling van frequente hoofdpijn : een Belgische apotheekstudie
Mehuys, E; Paemeleire, K; Van Hees, Thierry ULg et al

Conference (2014)

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See detailEffectiveness of PHARMAceutical care for patients with COPD (PHARMACOP): a randomized controlled trial
Tommelein, Eline; Mehuys, Els; Van Hees, Thierry ULg et al

in British Journal of Clinical Pharmacology (2014), 77(5), 756-766

AIM: Few well-designed randomized controlled trials (RCT) regarding the impact of community pharmacist interventions on pharmacotherapeutic monitoring of patients with Chronic Obstructive Pulmonary ... [more ▼]

AIM: Few well-designed randomized controlled trials (RCT) regarding the impact of community pharmacist interventions on pharmacotherapeutic monitoring of patients with Chronic Obstructive Pulmonary Disease (COPD) have been conducted. We assessed the effectiveness of a pharmaceutical care program for patients with COPD. METHODS: The PHARMACOP-trial is a single-blind 3-month RCT, conducted in 170 community pharmacies in Belgium, enrolling patients prescribed daily COPD medication, aged >/=50 years, and with a smoking history >/=10 pack-years. A computer-generated randomization sequence allocated patients to intervention (n=371), receiving protocol-defined pharmacist care, or control group (n=363), receiving usual pharmacist care (1:1 ratio, stratified by center). Interventions, focusing on inhalation technique and adherence to maintenance therapy, were carried out at start of the trial and at one month follow-up. Primary outcomes were inhalation technique and medication adherence. Secondary outcomes were exacerbation rate, dyspnea, COPD specific and generic health status and smoking behavior. RESULTS: From December 2010 to April 2011, 734 patients were enrolled. 42 patients (5.7%) were lost to follow-up. At the end of the trial, inhalation score (Mean estimated difference [Delta],13.5%; 95% Confidence Interval [CI], 10.8-16.1; P<.0001) and medication adherence (Delta, 8.51%; 95%CI, 4.63-12.4; P<.0001) were significantly higher in the intervention group compared to the control group. In the intervention group, a significantly lower hospitalization rate was observed (9 vs 35; Rate Ratio, 0.28; 95%CI, 0.12-0.64; P=.003). No other significant between-group differences were observed. CONCLUSION: Pragmatic pharmacist care programs improve the pharmacotherapeutic regime in patients with COPD and could reduce hospitalization rates. [less ▲]

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See detailLes problèmes liés aux médicaments dans les officines belges
Huysmans; De Wulf, I; Foulon, V et al

in Journal de Pharmacie de Belgique (2014), 1

Abstract INTRODUCTION: The identification, the management and if possible the prevention of drug related problems (DRP), are the main responsibilities of pharmacists. AIM: The aims of the study were 1/to ... [more ▼]

Abstract INTRODUCTION: The identification, the management and if possible the prevention of drug related problems (DRP), are the main responsibilities of pharmacists. AIM: The aims of the study were 1/to investigate the frequency and nature of drug related problems detected by community pharmacists, 2/to inventories the frequency and nature of the interventions by community pharmacists on prescribed medicines, and 3/to evaluate whether there is a difference between DRP detection at the moment of dispensing versus in a quiet setting (a posteriori detection). METHOD: All trainees of the participating universities of Belgian were asked to contribute to a observational study. Participating pharmacists quantified DRP's and their interventions on prescribed medicines for 5 days. Registrations were made by using a web tool based on an adapted version of the classification list of PCNE. The registration took place in two phases, at the time of delivery as well as in an a posteriori verification of the prescriptions with the pharmaceutical record file of the patients. RESULTS: The study was conducted from November 2012 to April 2013 in 534 community-pharmacies with internship. During this period 9.869 prescriptions (15%) with at least one DRP were detected on a total of 64.962 prescriptions treated by tutor pharmacists. Since there could be more than one problem on a prescription, 15.952 DRP's were registered. 2.597 of the DRP's were detected by a posteriori verification. 75% of all problems had a technical cause and 37% were clinical in nature. Under the technical causes an incomplete prescription was the most common. The most frequently registered clinical causes were a drug interaction, an inopportune time of intake, a too high or too low dose and an unsuitable drug. Participating pharmacists solved almost 3 of the 4 detected DRP's. In more than half of the DRP's, the patient was verbally and/or written informed. In 44% of the a posteriori discovered problems, the pharmacist intervened. CONCLUSION: Pharmacist detected one or more DRP's with 15% of the prescriptions. Analysis of a prescription prior to dispensing the medicines therefore appears necessary. The active intervention of the pharmacist in 83% of the problems indicates that he contributes to the optimization of drug therapy with a potential increase in the quality of life of the patient and a reduction in the cost of healthcare. The a posteriori discovered DRP's demonstrate the need for pharmacist lead meditation reviews possibly together with the physician and/or patient. [less ▲]

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See detailDrug related problems and interventions of pharmacists on prescribed medicines in Belgium
De Wulf, Isabelle; Boussery, Koen; De Vriese, Carine et al

in International Journal of Clinical Pharmacy [=IJCP] (2013, June), 35(3), 497

Aim of project/study (1) To study the frequency and nature of drug related problems (DRP) detected by community pharmacists and internship students when dispensing prescribed medicines. (2) To investigate ... [more ▼]

Aim of project/study (1) To study the frequency and nature of drug related problems (DRP) detected by community pharmacists and internship students when dispensing prescribed medicines. (2) To investigate the nature and frequency of interventions by pharmacists. (3) To study whether there is a difference between DRP detection at the moment of dispensing versus in a quiet setting. [less ▲]

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See detailLes génériques d’antibiotiques : une fausse bonne idée ?
Van Hees, Thierry ULg

Scientific conference (2013, May 07)

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See detailLe rôle du pharmacien comme conseiller en allaitement: perception des étudiants en pharmacie
Noirhomme-Renard, Florence ULg; Osorio Lopez, Rosa Elena; Gosset, Christiane ULg et al

Conference (2012, September 15)

L’OMS et l’UNICEF recommandent un allaitement maternel exclusif durant les six premiers mois de vie et un allaitement maternel complété jusque deux ans. En Belgique, l’avis du Conseil Supérieur de la ... [more ▼]

L’OMS et l’UNICEF recommandent un allaitement maternel exclusif durant les six premiers mois de vie et un allaitement maternel complété jusque deux ans. En Belgique, l’avis du Conseil Supérieur de la Santé relatif à la vente exclusive en pharmacie des préparations pour nourrissons (2008) souligne « l’importance d’un conseil éclairé de la part d’un universitaire sensibilisé et formé aux problématiques de santé et de nutrition ». Le pharmacien, par le contact fréquent qu’il a avec les jeunes parents, peut donc jouer un rôle dans l’allaitement. <br />Cette étude vise à explorer la perception du rôle du pharmacien comme conseiller en allaitement. <br />Cinquante-trois étudiants de dernière année de pharmacie de l’Université de Liège ont complété un questionnaire incluant des questions relatives à leurs perceptions, leur niveau de connaissances et leur expérience en matière d’allaitement, ainsi qu’une échelle d’attitude vis-à-vis de l’alimentation du nourrisson, l’IIFAS (Iowa Infant Feeding Attitude Scale). <br />92% des étudiants pensent que le pharmacien a un rôle (très) important à jouer comme conseiller en allaitement à différents niveaux (recommandations, prise de médicaments, lait artificiel,…), et 77% estiment qu’il peut influencer les décisions prises par les mères, même si l’officine n’apparaît pas toujours comme un lieu propice pour répondre en toute discrétion aux questions posées (41%). <br />Bien que l’expérience professionnelle et personnelle des étudiants soit faible, leur attitude est plutôt favorable à l’allaitement maternel selon l’échelle IIFAS (score de 61.25 ± 7.17). Toutefois, les étudiants évaluent globalement leur niveau de connaissance comme faible à très faible (insuffisance de lait maternel, stimulation de la lactation, utilisation du tire-lait, conservation du lait maternel, stérilisation des biberons,…). <br />Les futurs pharmaciens estiment avoir un rôle de conseiller important en matière d’allaitement, mais il y aurait lieu de renforcer leur curriculum de formation actuel pour leur permettre de remplir adéquatement, en officine, ce rôle de conseiller auprès des parents. [less ▲]

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