MICROPOLLUTANTS ISSUES: A MODELLING STUDY OF HEAVY METALS WITHIN TWO FRENCH BASINS AND A TEST APPLICATION TO COCAINE IN BELGIUMDeliège, Jean-François ; Everbecq, Etienne ; Grard, Aline et alPoster (2010, April) European policies (European Framework Directive: Water 2000/60/CE, Directive 76/464/CE) impose to reduce the releases of about a hundred substances in surface water. In the last years, the AQUAPOLE has ... [more ▼] European policies (European Framework Directive: Water 2000/60/CE, Directive 76/464/CE) impose to reduce the releases of about a hundred substances in surface water. In the last years, the AQUAPOLE has been involved in two studies related to this matter. First, on the request and with the financial support of both the French Ministry of Environment and ONEMA (“Office National de l’Eau et des Milieux Aquatiques”), INERIS (“Institut National de l’Environnement Industriel et des Risques”) drew up the guidelines of a methodology allowing fixing the local Limit Values to Emission so as to abide by the quality standards on the whole watershed. Within this context, INERIS wishes to test the use of pollutant transfer models on pilot sub-basins. The PEGASE model has been used to simulate micropollutants on two concrete use cases (1): (iii) in the Meuse sub-basin, managed by the French Water Agency Rhine-Meuse, for simulations concerning cadmium and zinc; (iv) in the Adour sub-basin, managed by the French Water Agency Adour-Garonne, for simulations applied to cadmium and copper. The choice of each substances and sub-basins was made by mutual agreement between INERIS, the concerned Water Agencies, and the AQUAPOLE. A major selection criterion for the substances and the sub-basins was the availability of data (sources and in situ measurements). For the second study, the PEGASE model has been adapted to describe the cocaine’s behaviour (using a stable metabolite of the cocaine in the environment: the benzoylecgonine (BZE)) in waste water, waste water treatment plants (WWTP) and surface water (2). The cocaine is newly described in the model as an additional micropollutant (PEGASE already treats numerous heavy metals), thanks to the implementation of new state variable equations and their specific parameterizations. Simulations of BZE have been done in the Walloon and Flemish regions, where many measurements from the COWAT project (3) were available. The first results are showing good agreement between calculated and measured values. The ability of the model to simulate the fate of studied micropollutants (cadmium, zinc, copper, and the cocaine derivatives) in surface waters should be enhanced and extended to other substances and basins. Moreover, additional data still have to be collected and measured. [less ▲] Detailed reference viewed: 50 (15 ULg) Résidus de médicaments dans les eaux de rivièreTheunis, Laetitia ![]() Conference (2010, February) Detailed reference viewed: 46 (8 ULg) Le Cannabis: historique, culture et modes d'utilisationTheunis, Laetitia ; De Backer, Benjamin ; Charlier, Corinne ![]() in Regards croisés sur le Cannabis (2010) Detailed reference viewed: 41 (13 ULg) Innovative development and validation of an HPLC/DAD method for the qualitative and quantitative determination of major cannabinoids in cannabis plant materialDe Backer, Benjamin ; Debrus, Benjamin ; Lebrun, Pierre et alin Journal of Chromatography. B : Analytical Technologies in the Biomedical & Life Sciences (2009), 877(32), 4115-4124 GC is commonly used for the analysis of cannabis samples, e.g. in forensic chemistry. However, as this method is based on heating of the sample, acidic forms of cannabinoids are decarboxylated into their ... [more ▼] GC is commonly used for the analysis of cannabis samples, e.g. in forensic chemistry. However, as this method is based on heating of the sample, acidic forms of cannabinoids are decarboxylated into their neutral counterparts. Conversely, HPLC permits the determination of the original composition of plant cannabinoids by direct analysis. Several HPLC methods have been described in the literature, but most of them failed to separate efficiently all the cannabinoids or were not validated according to general guidelines. By use of an innovative methodology for modelling chromatographic responses, a simple and accurate HPLC/DAD method was developed for the quantification of major neutral and acidic cannabinoids present in cannabis plant material: Δ9-tetrahydrocannabinol (THC), THC-acid (THCA), cannabidiol (CBD), CBD-acid (CBDA), cannabigerol (CBG), CBG-acid (CBGA) and cannabinol (CBN). Δ8-tetrahydrocannabinol (∆8-THC) was determined qualitatively. Following the practice of design of experiments, predictive multilinear models were developed and used in order to find optimal chromatographic analytical conditions. The method was validated following an approach using accuracy profiles based on β-expectation tolerance intervals for the total error measurement, and assessing the measurements uncertainty. This analytical method can be used for diverse applications, e.g. plant phenotype determination, evaluation of psychoactive potency and control of material quality. [less ▲] Detailed reference viewed: 251 (83 ULg) Cocaïne and metabolites in waste and surface water across Belgium.; ; Theunis, Laetitia et alin Environmental Pollution (2009), 157 Detailed reference viewed: 84 (45 ULg) Can cocaine use be evaluated through analysis of wastewater? A nation-wide approach conducted in Belgium; ; Theunis, Laetitia et alin Addiction (2009), 104 Detailed reference viewed: 62 (26 ULg) Spatial and temporal variations in the occurrence of cocaine and benzoylecgonine in waste- and surface water from Belgium and removal during wastewater treatment; ; Theunis, Laetitia et alin Water Research (2009), 43 Detailed reference viewed: 27 (12 ULg) Lindane et goudron dans les shampoings: quelle toxicité ?Theunis, Laetitia ![]() Conference (2008, December) Detailed reference viewed: 13 (3 ULg) COcaine in WATerTheunis, Laetitia ; Dubois, Nathalie ; et alPoster (2008, September) Detailed reference viewed: 17 (4 ULg) GEOCAN - Etude de la part de marché occupée par le cannabis cultivé en Belgique sur le marché belge du cannabisTheunis, Laetitia ; De Backer, Benjamin ; et alPoster (2008) Detailed reference viewed: 44 (5 ULg) Cocaïne dans nos rivières : une approche méthodologique originale dans le domaine de la toxicologie environnementaleTheunis, Laetitia ; ; et alin Revue Médicale de Liège (2008), 63(S1), 39-43 Detailed reference viewed: 94 (30 ULg) COcaine in WATer - Cocaïne et ses métabolites dans les eaux de surface et les eaux de stations d'épuration en BelgiqueTheunis, Laetitia ; Conference (2008) Detailed reference viewed: 7 (3 ULg)![]() Cocaïne and metabolites in waste and surface water across Belgium - a monitoring study; ; et al Poster (2008) Detailed reference viewed: 21 (8 ULg) |
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