Showing results 1 to 20 of 24
   Feline polymorphonuclear neutrophils produce pro-inflammatory cytokines following exposure to Microsporum canisCambier, Ludivine  ; ; et alin Veterinary Microbiology (2013), 162(2-4), 800-805 Detailed reference viewed: 33 (8 ULg) Inhibition of the keratinolytic subtilisin protease Sub3 from Microsporum canis by its propeptide (proSub3) and evaluation of the capacity of proSub3 to inhibit fungal adherence to feline epidermis; ; Dumez, Marie-Eve et alin Veterinary Microbiology (2012), 159(3-4), 479-484 Detailed reference viewed: 6 (2 ULg)Réponse cytokinique et expression du complexe majeur d'histocompatibilité de type II par les cellules dendritiques félines exposées à différents constituants de Microsporum canis; Cambier, Ludivine ; Defaweux, Valérie et alConference (2011) Detailed reference viewed: 33 (11 ULg)Rôle des cellules Th17 dans les maladies infectieuses et auto-immunesCambier, Ludivine ; Defaweux, Valérie ; Baldo, Aline et alin Annales de Médecine Vétérinaire (2011), 154 Detailed reference viewed: 113 (32 ULg)Cytokinic response and MHC class II expression in feline dendritic cells exposed to Microsporum canis componentsMignon, Bernard ; Hubert, Pascale ; Defaweux, Valérie et alConference (2010) Detailed reference viewed: 40 (21 ULg)Fungalysin and Dipeptidyl-Peptidase Gene Transcription in Microsporum canis Strains Isolated from Symptomatic and Asymptomatic CatsMathy, Anne ; Baldo, Aline ; et alPoster (2010) Detailed reference viewed: 37 (18 ULg)Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermisBaldo, Aline ; Mathy, Anne ; et alin British Journal of Dermatology (2010), 162(5), 990-997 Detailed reference viewed: 44 (18 ULg)Role of Microsporum canis secreted proteases in adherence to and invasion of epidermisMathy, Anne ; Baldo, Aline ; Cambier, Ludivine et alConference (2010) Detailed reference viewed: 26 (10 ULg)Fungalysin and dipeptidyl-peptidase gene transcription in Microsporum canis strains isolated from symptomatic and asymptomatic catsMathy, Anne ; Baldo, Aline ; Schoofs, Laura et alin Veterinary Microbiology (2010), 146(1-2), 179-182 Detailed reference viewed: 49 (26 ULg)Role of Microsporum canis antigens in the development of a specific and protective immune responseCamponova, Paméla ; ; Baldo, Aline et alConference (2009) Detailed reference viewed: 52 (7 ULg)Cytokinic response of feline dermatophytes towards Microsporum canis and fungal componentsMignon, Bernard ; ; Camponova, Paméla et alConference (2009) Detailed reference viewed: 33 (6 ULg)Involvement of the secreted serine protease Sub3 of Microsporum canis in adherence to feline epidermisMathy, Anne ; ; et alConference (2009) Detailed reference viewed: 25 (9 ULg)Immunization and dermatophytesBaldo, Aline ; ; Mathy, Anne et alConference (2009) Detailed reference viewed: 23 (6 ULg)Secreted subtilisins of Microsporum canis are involved in adhesion of arthroconidia to feline corneocytesMignon, Bernard ; ; Mathy, Anne et alConference (2008) Detailed reference viewed: 18 (10 ULg)RNA silencing in the dermatophyte Microsporum canis; ; Baldo, Aline et alin FEMS Microbiology Letters (2007), 275(1), 38-45 Dermatomycoses caused by Microsporum canis are frequent in domestic animals and easily transmissible to humans. Several proteases secreted by this fungus were identified as potential virulence factors ... [more ▼] Dermatomycoses caused by Microsporum canis are frequent in domestic animals and easily transmissible to humans. Several proteases secreted by this fungus were identified as potential virulence factors, but the construction of deficient strains is required to investigate their role in the pathogenesis of the disease. Using target genes encoding two of these proteases, a first evaluation of the utility of RNA-mediated silencing as a reverse genetic tool in dermatophytes was carried out. SUB3 and DPPIV, respectively coding for a subtilisin and a dipeptidyl peptidase, were both down-regulated, by means of two plasmid constructs designed to express an RNA hairpin that corresponds to part of their respective sequence. The degree of attenuation was evaluated by enzymatic assay of the transformants culture supernatants, and by real-time reverse transcriptase-polymerase chain reaction. Enzymatic activities and expression levels varied from less than 5% to 100% of that of control transformants obtained with plasmid without hairpin inserts. Inhibition was globally more efficient for SUB3 than for DPPIV. These results show that RNA silencing can be used for functional genomics in M. canis, and particularly to circumvent the limits and technical difficulties of conventional disruption methods. [less ▲] Detailed reference viewed: 61 (5 ULg)Les mécanismes d'adhérence des champignons responsables de mycoses superficiellesBaldo, Aline ; Mathy, Anne ; et alin Annales de Médecine Vétérinaire (2007), 151 Detailed reference viewed: 45 (8 ULg)Reconstructed interfollicular feline epidermis as a model for the screening of drugs against Microsporum canisMignon, Bernard ; ; Baldo, Aline et alin Veterinary Dermatology (2007), 18 Detailed reference viewed: 22 (5 ULg)Kinetics of Microsporum canis adherence using an in vitro model of reconstituted feline epidermisBaldo, Aline ; ; et alConference (2006) Detailed reference viewed: 7 (1 ULg)A randomized, double-blinded, placebo-controlled study on the efficacy of a new antifungal (compound MNLP1242) against Microsporum canis dermatophytosis in experimentally infected guinea pigsMignon, Bernard ; ; Baldo, Aline et alin Veterinary Dermatology (2006), 17 Detailed reference viewed: 49 (9 ULg)Recent findings on the pathogenesis of dermatophytoses in dogs and catsMignon, Bernard ; ; et alin Revista Scientia Parasitologica (2006), 7(3/4), 7-15 Detailed reference viewed: 11 (3 ULg)
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