References of "Szepetiuk, Grégory"
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See detailFondements physico-biologiques de la fluorescence cutanee - Revue.
SZEPETIUK, Grégory ULg; FRANCHIMONT, Claudine ULg; QUATRESOOZ, Pascale ULg et al

in Pathologie Biologie (2012), 60

Fluorescence is a peculiar aspect of photoluminescence. Some intrinsic components of the skin are fluorophores. Other synthetic components are metabolized into fluorophores. These characteristics may be ... [more ▼]

Fluorescence is a peculiar aspect of photoluminescence. Some intrinsic components of the skin are fluorophores. Other synthetic components are metabolized into fluorophores. These characteristics may be used for identifying some specific aspects of skin physiopathology. Recent technological evolution has provided new devices bringing sensitive and specific information from the skin. This review presents a synthesis of the progress made in the field of fluorescence and specular reflexion of incident UV light on the skin. [less ▲]

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See detailLa peau infectée par des bactéries au cours des hémopathies malignes.
FRANCHIMONT, Claudine ULg; SZEPETIUK, Grégory ULg; LESUISSE, Marianne et al

in Dermatologie Actualité (2012), 133

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See detailLa drosophile, les récepteurs Toll-like et nous.
PIERARD, Gérald ULg; FRANCHIMONT, Claudine ULg; SZEPETIUK, Grégory ULg et al

in Dermatologie Actualité (2012), 132

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See detailL'image du mois. Calcinose idiopathique du scrotum.
Paquet, Philippe ULg; Devillers, C.; Szepetiuk, Grégory ULg et al

in Revue Médicale de Liège (2010), 65(3), 113-4

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See detailThe therapeutic potential of TNF-alpha antagonists for skin psoriasis comorbidities.
Pierard, Gérald ULg; Pierard, Claudine ULg; Szepetiuk, Grégory ULg et al

in Expert Opinion on Biological Therapy (2010), 10(8), 1197-208

IMPORTANCE OF THE FIELD: Alopecia, psoriatic arthritis, the metabolic syndrome, inflammatory bowel diseases and cardiovascular diseases may occur as skin psoriatic comorbidities. TNF-alpha antagonists are ... [more ▼]

IMPORTANCE OF THE FIELD: Alopecia, psoriatic arthritis, the metabolic syndrome, inflammatory bowel diseases and cardiovascular diseases may occur as skin psoriatic comorbidities. TNF-alpha antagonists are used to treat psoriasis. Adalimumab is one of the recognized active agents for this indication. AREAS COVERED IN THIS REVIEW: The current peer-reviewed publications and presentation of original findings. WHAT THE READER WILL GAIN: Adalimumab is active on recalcitrant psoriasis and some of its comorbidities, particularly arthropathies and Crohn's disease. However, the progression of the radiological alterations is limited with regression of the bony erosions. Psoriatic enthesopathy also regresses. Mortality associated with psoriasis arthropathy is on the decline. Crohn's disease, the most frequent inflammatory bowel comorbidity of psoriasis, is responsive to adalimumab. The effect of adalimumab on the metabolic syndrome and cardiovascular involvement is more erratic. The spectacular effects of adalimumab may be associated with some adverse effects. In particular, despite a marked reduction in the psoriasis area-and-severity index (PASI) score some new acute lesions of cutaneous psoriasis may develop corresponding to paradoxical psoriasis. Other potential adverse effects include infections, granulomas, rapid growth of cancers and occurrence of lymphomas. TAKE HOME MESSAGE: Adalimumab frequently controls moderate-to-severe forms of cutaneous psoriasis and some of its comorbidities. [less ▲]

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See detailL'image du mois. Langue villeuse noire.
Szepetiuk, Grégory ULg; Pierard, Claudine ULg; Pierard, Gérald ULg

in Revue Médicale de Liège (2010), 65(4), 169-70

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See detailAvoir le rythme dans la peau.
Szepetiuk, Grégory ULg; Franchimont, Claudine ULg; Pierard, Gérald ULg

in Dermatologie Actualité (2010), 118

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See detailComment j'explore... une dermatose hypochromique ou achromique.
Devillers, C.; Szepetiuk, Grégory ULg; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2010), 65(2), 109-12

Some skin disorders typically share in common a hypochromic or achromic aspect. The diagnostic approach relies on a directed evaluation of the medical history and a careful clinical examination. In ... [more ▼]

Some skin disorders typically share in common a hypochromic or achromic aspect. The diagnostic approach relies on a directed evaluation of the medical history and a careful clinical examination. In addition, the cyanoacrylate skin surface biopsy helps establish the diagnosis. [less ▲]

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See detailL'image du mois. Chancre mixte, combinaison d'un chancre mou et d'un chancre syphilitique.
Henry, Frédérique ULg; Devillers, Céline ULg; Szepetiuk, Grégory ULg et al

in Revue Médicale de Liège (2009), 64(4), 177-8

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See detailFungal chitin-glucan scaffold for managing diabetic xerosis of the feet in menopausal women.
Quatresooz, Pascale ULg; Franchimont, Claudine ULg; Szepetiuk, Grégory ULg et al

in Expert Opinion on Pharmacotherapy (2009), 10(14), 2221-9

BACKGROUND: Corneocyte accumulation (hyperkeratosis, xerosis) commonly occurs in the stratum corneum (SC) of the feet of diabetic patients, as well as menopausal women. OBJECTIVE: To compare the effects ... [more ▼]

BACKGROUND: Corneocyte accumulation (hyperkeratosis, xerosis) commonly occurs in the stratum corneum (SC) of the feet of diabetic patients, as well as menopausal women. OBJECTIVE: To compare the effects of a 2.5% chitin-glucan formulation with its placebo, and commercially available glycerol formulations. METHODS: This two-step controlled double-blind, randomized, intra-individual study was performed in 30 type 1 and 2 diabetic menopausal women suffering from xerosis of the feet. The formulations were applied once daily for 3 weeks. Electrometric assessments were performed on three sites of the feet at entry in the study, at weekly intervals during the treatment phase, and in a 2-week follow-up out of treatment. Positive controls consisted in two commercially available formulations enriched in glycerol. RESULTS: Data revealed an unequivocal benefit provided by the 2.5% chitin-glucan formulation compared with placebo. The electrometric values were significantly higher at each evaluation time during both treatment and follow-up phases. The two glycerol-enriched formulations showed slightly different kinetics of SC moisturization. A steep increase was followed by a plateau level and a rapid decline after stopping the treatments. CONCLUSION: The increased moisturization of the SC of the sole probably improves the desquamation process and reduces xerosis of the soles. [less ▲]

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See detailSchöpf-Schulz-Passarge syndrome with pili torti: a new association?
Szepetiuk, Grégory ULg; Vanhooteghem, Olivier ULg; Muller, G. et al

in European Journal of Dermatology (2009), 19(5), 1-2

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See detailBiometrology of physical properties of skin in thyroid dysfunction.
Szepetiuk, Grégory ULg; Pierard, Gérald ULg; Betea, Daniela ULg et al

in Journal of the European Academy of Dermatology & Venereology (2008), 22(10), 1173-1177

OBJECTIVE: There is ample clinical evidence that skin is responsive to physiopathological levels of circulating thyroid hormones. The aim of the study was to assess some physical changes of the skin in ... [more ▼]

OBJECTIVE: There is ample clinical evidence that skin is responsive to physiopathological levels of circulating thyroid hormones. The aim of the study was to assess some physical changes of the skin in the presence of moderate thyroid dysfunction. SETTING: University Hospital. PATIENTS AND METHODS: A total of 119 adults suffering from hypothyroidism or hyperthyroidism and 60 healthy controls were enrolled in this study. Hormonal dosages (TSH, fT3, fT4) were assessed in the serum. A series of biometrological assessments were also performed on the volar and dorsal aspects of the forearms. These included electrometric assessments (Nova Dermal Phase Meter, Corneometer), evaporimetry (Tewameter)), colorimetry (Mexameter), ultrasound shear wave propagation (Reviscometer) and squamometry X. Correlations were searched between each of the serum hormonal dosages and each of the biometrological parameters. RESULTS: The hormonal changes in the untreated patients with thyroid dysfunction were modest in intensity. A few outlier values with regard to the normal range were found for each biometrological parameter. No correlations were found between fT3 or fT4 and each of the physical parameters. By contrast, significant negative linear correlations were found between thyroid-stimulating hormone (TSH) and skin hydration measured by the Corneometer and the Nova DPM. CONCLUSION: This multipronged exploratory study shows that direct or indirect effects of TSH may influence the stratum corneum hydration. This correlation seemed very sensitive, as no other specific biophysical parameter was significantly correlated with the thyroid hormonal concentrations in the serum. However, our findings do not exclude the possibility of some other skin changes supervening in case of more severe thyroid dysfunction. The mechanism by which TSH alters the stratum corneum hydration is yet unknown. [less ▲]

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See detailManifestations cutanées des pathologies endocriniennes
Quatresooz, Pascale ULg; Thirion, Laurence; Pierard, Claudine ULg et al

in Revue Médicale de Liège (2006), 61(2), 104-8

Some cutaneous lesions accompany or reveal endocrine disorders. Identifying the endocrinopathy is very important because it sometimes allows corrective rather than symptomatic treatment. The most ... [more ▼]

Some cutaneous lesions accompany or reveal endocrine disorders. Identifying the endocrinopathy is very important because it sometimes allows corrective rather than symptomatic treatment. The most frequenly involved diseases include thyrotoxicosis, hypothyroidism, the auto-immune disorders of thyroid, Cushing syndrome, Addison disease, acromegaly, androgen-dependent disorders, hypopituitarism, hypoparathyroidism, pseudohypoparathyroidism and diabetes mellitus. [less ▲]

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