References of "Stoilova, Olya"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailC-60-containing nanostructured polymeric materials with potential biomedical applications
Stoilova, Olya; Jérôme, Christine ULg; Detrembleur, Christophe ULg et al

in Polymer (2007), 48(7), 1835-1843

Star-shaped polymers with a fullerene (C-60) Core and an unexpanded structure were successfully prepared by reaction Of C60 with amino end-capped polyesters HxC60(NHPCLn)(x) and polyethers HxC60(NHPEG(n ... [more ▼]

Star-shaped polymers with a fullerene (C-60) Core and an unexpanded structure were successfully prepared by reaction Of C60 with amino end-capped polyesters HxC60(NHPCLn)(x) and polyethers HxC60(NHPEG(n))(x), respectively. Upon irradiation of these C-60-derivatives, a large amount of singlet oxygen was released. Compared to previously synthesized star-shaped azafulleroids with an expanded structure, the photosensitivity of HxC60(NHPCLn)(x) is higher as assessed by a higher production of singlet oxygen. The cytotoxicity of the photoactive water-soluble HxC60(NHPEG(n))(x) derivatives was tested against THP-1 cells and expressed in terms of cell viability. Moreover, they were processed as micro-/nanosized fibers by electrospinning, which however required the addition of poly(F-caprolactone) (PCL). The diameter distribution of the fibers was trimodal, where the fraction with the 270 nm average diameter was the major population. Because of their photoactivity, the herein reported star-shaped C-60-derivatives are promising candidates for photodynamic cancer therapy and treatment of multidrug resistant pathogens. (c) 2007 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 58 (3 ULg)
Full Text
Peer Reviewed
See detailNew nanostructured materials based on fullerene and biodegradable polyesters
Stoilova, Olya; Jérôme, Christine ULg; Detrembleur, Christophe ULg et al

in Chemistry of Materials (2006), 18(20), 4917-4923

Star-shaped poly(epsilon-caprolactone) (PCL) with a fullerene (C-60) core, C-60[N(CH2)(12)OPCLOH](x), was successfully synthesized by reaction of azide-terminated PCL with C-60. Both the experimental ... [more ▼]

Star-shaped poly(epsilon-caprolactone) (PCL) with a fullerene (C-60) core, C-60[N(CH2)(12)OPCLOH](x), was successfully synthesized by reaction of azide-terminated PCL with C-60. Both the experimental conditions and the stoichiometry were optimized, such that an average of six PCL chains was grafted per fullerene core. The molecular weight of the polyester chains directly controlled the length of the arms of the star-shaped polymers. Singlet oxygen was generated on irradiation of the C-60[N(CH2)(12)OPCLOH] x nanohybrids. These C-60[N(CH2)(12)OPCLOH](x) nanohybrids were then processed in two kinds of nanomaterials. First, they were encapsulated within the core of micelles formed by biocompatible amphiphilic block copolymers. In water, the particle size distribution of these nanoparticles was narrow, and their diameter was in the range of 100 to 200 nm. Second, C-60-containing micro-/nanosized polymer fibers were prepared, for the first time, by electrospinning. The average diameter of the fibers was varied by tuning the PCL/C-60[N(CH2)(12)OPCLOH](x) weight ratio. Grafting of polyester chains onto C-60 is thus a suitable strategy for producing easily processable C-60 and attractive building blocks for incorporation of C-60 in nanomaterials. [less ▲]

Detailed reference viewed: 40 (4 ULg)
Full Text
Peer Reviewed
See detailPreparation of well-defined PVOH/C60 nanohybrids by cobalt-mediated radical polymerization of vinyl acetate
Detrembleur, Christophe ULg; Stoilova, Olya; Bryaskova, Rayna ULg et al

in Macromolecular Rapid Communications (2006), 27(7), 498-504

Poly(vinyl acetate) chains end-capped by a Co(acac)(2) complex [PVAc-Co(acac)(2)] were prepared by bulk cobalt-mediated radical polymerization (CMRP) of vinyl acetate and used for grafting fullerene (C60 ... [more ▼]

Poly(vinyl acetate) chains end-capped by a Co(acac)(2) complex [PVAc-Co(acac)(2)] were prepared by bulk cobalt-mediated radical polymerization (CMRP) of vinyl acetate and used for grafting fullerene (C60) with four PVAc arms at low temperature (30 degrees C). A photoactive water-soluble poly(vinyl alcohol)/C60 nanohybrid was then prepared by hydrolysis of the PVAc arms of the nanohybrid. Because of photoactivity and very low cytotoxicity, this type of water-soluble nanohybrid is very promising for the photodynamic cancer therapy. [less ▲]

Detailed reference viewed: 35 (5 ULg)
See detailFunctionlization of biodegradable aliphatic polyesters by mannose-residue for the design of surface-modified polymeric nanoparticles
Rieger, Jutta ULg; Stoffelbach, François; Stoilova, Olya et al

Conference (2005, June 01)

Detailed reference viewed: 10 (2 ULg)
See detailFullerene containing (co)polymers for biomedical applications
Stoilova, Olya; Detrembleur, Christophe ULg; Jérôme, Christine ULg et al

Conference (2005, June 01)

Detailed reference viewed: 16 (2 ULg)