References of "Snaps, Frédéric"
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See detailSalmeterol or doxycycline do not inhibit acute bronchospasm and airway inflammation in cats with experimentally-induced asthma
Leemans, J.; Kirschvink, N.; Bernaerts, Frederique ULg et al

in Veterinary Journal (2011)

The objective of this study was to determine if inhaled salmeterol, a long-acting β2-adrenergic agonist, and oral doxycycline, a tetracycline antibiotic displaying matrix metalloproteinase (MMP ... [more ▼]

The objective of this study was to determine if inhaled salmeterol, a long-acting β2-adrenergic agonist, and oral doxycycline, a tetracycline antibiotic displaying matrix metalloproteinase (MMP) inhibitory activity, reduce airway inflammation and obstruction in cats with experimentally-induced asthma. Eight Ascaris suum (AS)-sensitised cats were enrolled in a prospective study in which they underwent four AS-challenges at 1 month intervals. The challenged animals were given no treatment or were treated on 4 consecutive days with either: (1) oral prednisolone (1 mg/kg twice daily), (2) inhaled salmeterol (50 μg twice daily), or (3) oral doxycycline (5 mg/kg twice daily), according to a randomised cross-over design. Inhibition of allergen-induced early (EAR) and late (LAR) asthmatic reactions were assessed by barometric whole-body plethysmography. Cytology and measurement of MMP-2 and -9 activities were carried out on bronchoalveolar lavage fluid (BALF). Although none of the treatments prevented the EAR, prednisolone treatment inhibited the LAR. Relative to untreated cats, the eosinophil percentage and MMP-2 activity in BALF were significantly reduced following prednisolone treatment (P < 0.05). Short-term therapy with either salmeterol or doxycycline had no effect on the EAR or LAR or on airway inflammation. Given the chronic nature of this disease in cats, long-term therapy may be required to produce more favourable functional and clinical outcomes. [less ▲]

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See detailArterial head vascularization cartographies of normal metencephalic dogs using magnetic resonance angiography
Jacqmot, Olivier ULg; Snaps, Frédéric ULg; MAQUET, Nathalie ULg et al

in Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology (2011), 294

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See detailEffect of short-term oral and inhaled corticosteroids on airway inflammation and responsiveness in a feline acute asthma model
Leemans, Jérôme; Kirschvink, Nathalie; Clercx, Cécile ULg et al

in Veterinary Journal (2011)

The objective of this study was to investigate whether high-dose inhaled fluticasone propionate (FP), alone or in combination with salmeterol (SAL), is as effective as oral prednisolone in reducing airway ... [more ▼]

The objective of this study was to investigate whether high-dose inhaled fluticasone propionate (FP), alone or in combination with salmeterol (SAL), is as effective as oral prednisolone in reducing airway inflammation and obstruction in cats with experimentally-induced acute asthma. Six cats sensitised to Ascaris suum (AS) were enrolled in a prospective controlled therapeutic trial and underwent four aerosol challenges, at 1-month intervals with AS allergen. The allergen - stimulated animals received four consecutive days treatment with either oral prednisolone at 1mg/kg twice daily, 500μg of FP inhaled twice daily, or a combination of FP/SAL at 500μg/50μg inhaled twice daily, respectively, according to a randomised cross-over design. Treatment-related changes in lung function, airway responsiveness (AR) and bronchoalveolar lavage fluid (BALF) cytology were assessed. Barometric whole-body plethysmography (BWBP) was used for the assessment of respiratory variables and AR. No significant differences in respiratory rate or Penh (an estimate of airflow limitation measured by BWBP) were detected among treatment groups. Allergen-induced airway hyper-responsiveness was significantly inhibited by all three steroid treatments (P<0.05). The mean BALF eosinophil percentage (±SEM) was lower after oral and inhaled corticosteroid treatment and these changes were significant for groups receiving prednisolone and the FP/SAL combination. Findings suggest high-dose FP, particularly in combination with SAL, is effective in ameliorating airway inflammation and hyper-responsiveness in this model of acute feline asthma, and highlight the potential use of these drugs in cats experiencing acute exacerbations of the naturally occurring disease. [less ▲]

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See detailTranssinusoidal portal vein embolization with ethylene vinyl alcool polymer ( onyx): a feasibility study in pigs
Smits Maarten; Vanlangenhove Peter; Sturm Emiel et al

in Cardiovascular & Interventional Radiology (2011)

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See detailComputed Tomographic Features of Choanal Atresia in a Friesian Foal
Van Galen, Gaby ULg; Bolen, Géraldine ULg; Verwilghen, Denis ULg et al

in Journal of Equine Veterinary Science (2010), 30(8), 436-440

A 3 week old Friesian foal colt was presented with a history of respiratory distress since birth. Endoscopy showed obstruction of the right nasal passage to the nasopharynx. Computed tomography (CT) was ... [more ▼]

A 3 week old Friesian foal colt was presented with a history of respiratory distress since birth. Endoscopy showed obstruction of the right nasal passage to the nasopharynx. Computed tomography (CT) was performed to further characterize this unilateral blockage: images showed demonstrated a complete membranous obstruction of the ventral meatus, together with a deviation of the vomer bone to the left. The diagnosis of unilateral choanal atresia was confirmed. This is the first report describing CT features of choanal atresia in a foal. [less ▲]

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See detailPneumoinie à pseudomonas aeruginosa chez le python indien
Gandar; Szalo; Etienne et al

in Monde Vétérinaire (Le) : European Veterinary Magazine (2010), 107

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See detailCharacterisation of the acute and reversible airway inflammation induced by cadmium chloride inhalation in healthy dogs and evaluation of the effects of salbutamol and prednisolone.
Bolognin, M.; Kirschvink, N.; Leemans, Jérôme ULg et al

in Veterinary Journal (2009), 179(3), 443-450

The aims of this study were firstly to characterise a model of subclinical and reversible bronchial inflammation induced by cadmium chloride inhalation in healthy dogs and then to examine the effect of ... [more ▼]

The aims of this study were firstly to characterise a model of subclinical and reversible bronchial inflammation induced by cadmium chloride inhalation in healthy dogs and then to examine the effect of prednisolone or salbutamol treatment on the resulting bronchitis. The model characterisation and the effects of treatment were studied using clinical symptoms, haematology, thoracic radiography, bronchoscopy and bronchoalveolar lavage, barometric whole-body plethysmography and histamine broncho-provocation tests. In addition, the activity of matrix metalloproteinases (MMP)-2 and -9 were determined in serum and bronchoalveolar lavage fluid (BALF). Cadmium inhalation induced: (1) a transient bronchial inflammation, dominated by neutrophils; (2) a neutrophilia of the blood that persisted for up to 4weeks; (3) a transient increased bronchial reactivity, and (4) a significant increase in MMP-9 activity in the BALF. Prednisolone treatment reduced the influx of inflammatory cells into the BALF, but not significantly, had no effect on pulmonary function, and did not reduce of airway hypersensitivity. Salbutamol had almost no effect on any of the parameters investigated. [less ▲]

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See detailThe Norberg angle revisited
Comhaire, F.; Criel, A.; Dassy, C. et al

in American Journal of Veterinary Research (2009), 70(2), 228-235

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See detailTransinusoidal portal vein embolisation with Onyx: feasibility study in pigs
Smits; Hav; Vanlengenhoeve et al

Poster (2009)

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See detailEvaluation of computed tomographic anatomy of the equine metacarpophalangeal joint
Vanderperren, K.; Ghaye, Benoit ULg; Hoegaerts, M. et al

in American Journal of Veterinary Research (2008), 69(5), 631-638

OBJECTIVE: To determine the detailed computed tomography (CT) anatomy of the metacarpophalangeal (MCP) joint in healthy horses. SAMPLE POPULATION: 10 cadaveric forelimbs from 10 adult horses without ... [more ▼]

OBJECTIVE: To determine the detailed computed tomography (CT) anatomy of the metacarpophalangeal (MCP) joint in healthy horses. SAMPLE POPULATION: 10 cadaveric forelimbs from 10 adult horses without orthopedic disease. PROCEDURES: CT of the MCP joint was performed on 4 forelimbs. In 1 of the limbs, CT was also performed after intra-articular injection of 30 mL of contrast medium (40 mg of iodine/mL). Transverse slices 1-mm thick were obtained, and sagittal and dorsal planes were reformatted with a slice thickness of 2 mm. The CT images were matched with corresponding anatomic slices from 6 additional forelimbs. RESULTS: The third metacarpal bone, proximal sesamoid bones, and proximal phalanx could be clearly visualized. Common digital extensor tendon; accessory digital extensor tendon; lateral digital extensor tendon; superficial digital flexor tendon (including manica flexoria); deep digital flexor tendon; branches of the suspensory ligament (including its attachment); extensor branches of the suspensory ligament; collateral ligaments; straight, oblique, and cruciate distal sesamoidean ligaments; intersesamoidean ligament; annular ligament; and joint capsule could be seen. Collateral sesamoidean ligaments and short distal sesamoidean ligaments could be localized but not at all times clearly identified, whereas the metacarpointersesamoidean ligament could not be identified. The cartilage of the MCP joint could be assessed on the postcontrast sequence. CONCLUSIONS AND CLINICAL RELEVANCE: CT of the equine MCP joint can be of great value when results of radiography and ultrasonography are inconclusive. Images obtained in this study may serve as reference for CT of the equine MCP joint. [less ▲]

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See detailPrimary ciliary dyskinesia and situs inversus in a young dog.
Cavrenne, Romain; De Busscher, Virginie; Bolen, Géraldine ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2008), 163(2), 54-5

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See detailMagnetic resonance imaging arteriography of canine normal brain: an anatomic study
Jacqmot, Olivier ULg; Hoffmann, A. C.; Bustin, P. H. et al

Poster (2008)

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See detailRelation between body mass index and prevalence of hip dysplasia among different dog breeds
Comhaire, F.; Snaps, Frédéric ULg

in American Journal of Veterinary Research (2008), 69

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See detailLa méthode PenHip : un moyen de dépistage précoce de la dyspasie dans l'espèce canine.
Guévar, M.; Snaps, Frédéric ULg

in Pratique médicale & chirurgicale de l'animal de compagnie (2008), 43

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See detailComparison of T1 and T2 - weighted and Blade MRI sequences for examination of canine normal abdomen
Hoffmann; Buttin; Haye et al

Poster (2008)

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See detailPrimary ciliary dyskinesia in a family of Old English Sheepdogs
Billen, Frédéric ULg; Binst, Dominique; Geyskens, Valerie et al

in Proceedings of the 17th ECVIM-CA congress (2007, September)

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