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See detailThe internet as a source of information used by women after childbirth to meet their need for information: A web-based survey.
Slomian, Justine ULg; Bruyère, Olivier ULg; Reginster, Jean-Yves ULg et al

in Midwifery (2017), 48

OBJECTIVE: the aims of this survey were: (a) to evaluate the need of information after childbirth and what questions do 'new' mothers ask themselves; (b) to assess why and how women use the Internet to ... [more ▼]

OBJECTIVE: the aims of this survey were: (a) to evaluate the need of information after childbirth and what questions do 'new' mothers ask themselves; (b) to assess why and how women use the Internet to meet their need of information; (c) to describe how the respondents evaluate the reliability of the information found; (d) to understand how the information found on the Internet affects women's decision-making; and (e) to appreciate how health professionals react to the information found by the women. DESIGN: this study used a large web-based survey that was widely broadcasted on various websites and social networks. SETTING AND PARTICIPANTS: belgian women who had a child under 2 years old and who agreed to participate were included in the study. FINDINGS: 349 questionnaires were valid for analyses. After childbirth, 90.5% of women admitted to using the Internet to seek information about themselves or about their baby, regardless of socioeconomic status or age. There were various reasons for seeking information on the Internet, but the most frequent reason the women expressed was to find information 'on their own' (88.1%). The most searched for topic was breastfeeding. The women believed that the information was quite useful (82.7%) but they assigned an average score of 5.3 out of 10 for the quality of the information they found on the Internet. Approximately 80% of the women felt that the Internet helped them control a decision that they made 'a little', 'often' or 'very often'. Professionals are not always willing to talk about information found on the Internet with mothers. Therefore, many women believed that health professionals should suggest reliable Internet websites for new mothers. CONCLUSIONS: the integration of the Internet and new technologies could be a useful tool during postpartum management. [less ▲]

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See detailPrevalence of Concomitant Bone and Muscle Wasting in Elderly Women from the SarcoPhAge Cohort: Preliminary Results.
Locquet, Médéa ULg; Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg et al

in Journal of Frailty & Aging (2017), 6(1), 18-23

BACKGROUND: Recent studies suggest that bone and muscle wasting are closely interconnected. OBJECTIVE: The aim was of this study is to assess the prevalence of osteoporosis in a population of women ... [more ▼]

BACKGROUND: Recent studies suggest that bone and muscle wasting are closely interconnected. OBJECTIVE: The aim was of this study is to assess the prevalence of osteoporosis in a population of women diagnosed with sarcopenia. Participants, setting and design: We analyzed cross-sectional data of women, aged 65 years and above, for whom bone mineral density was available at the time of inclusion in the SarcoPhAge (Sarcopenia and Physical impairment with advancing Age) cohort, an ongoing prospective study with the aim to assess consequences of sarcopenia. MEASUREMENTS: Muscle strength was evaluated with a hydraulic hand-dynamometer, appendicular lean mass and bone mineral density by Dual-Energy X-Ray Absorptiometry and physical performance by the Short Physical Performance Battery test (SPPB). Sarcopenia was diagnosed according to the European Working Group on Sarcopenia in Older People definition, i.e. a low muscle mass plus either low muscle strength or low physical performance. A bone mineral density T-score equal to or below -2.5SD at the lumbar spine, at the total hip or at the femoral neck was used to define osteoporosis (World Health Organization definition). RESULTS: A total of 126 women aged 74.38+/-6.32 years were included. Among them, 26 were assessed with sarcopenia (20.6%) and 34 (27.0%) with osteoporosis. There were more osteoporotic women among sarcopenic subjects (46.1%) than among non-sarcopenic subjects (22.0%) (p-value=0.011). A significant lower appendicular lean mass index was observed in osteoporotic women (p-value=0.025). We also observed, in osteoporotic subjects, a lower muscle strength (p-value=0.023). Numerical values of bone mineral density were lower in the sarcopenic population but the differences did not reach the level of statistical significance. CONCLUSION: Our study demonstrated that muscle mass and strength are lower in patients with osteoporosis. Prospective changes in bone and muscle mass will be investigated during the follow-up of our cohort. [less ▲]

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See detailIdentification des besoins des mères dans l’année suivant leur accouchement : une étude qualitative.
Slomian, Justine ULg; EMONTS, Patrick ULg; Vigneron, Lara et al

in 44èmes Assises Nationales des Sages-Femmes (2016, May)

Contexte de l’étude : La grossesse et l’accouchement sont deux étapes fondamentales dans la vie d’une femme. Plusieurs études ont montré que le malaise psychologique était relativement fréquent dans ... [more ▼]

Contexte de l’étude : La grossesse et l’accouchement sont deux étapes fondamentales dans la vie d’une femme. Plusieurs études ont montré que le malaise psychologique était relativement fréquent dans l’année suivant un accouchement. Objectifs : L’objectif de cette étude était de déterminé les besoins des mères dans l’année suivant leur accouchement (qu’elles aient vécu un épisode psychologique pathologique ou non). Méthode : Plusieurs étapes qualitatives ont été entreprises dans cette étude. Premièrement, nous avons conduit 22 entretiens individuels et un focus group réunissant des mères ayant vécu ou non un épisode de détresse psychologique. Nous avons ensuite mené deux autres focus : un avec des professionnels de la santé, l’autre avec des pères. Le but était de comparer les besoins maternels avec la perception des professionnels ainsi que des pères. Règles éthiques : Cette étude a reçu l’accord du comité d’éthique hospitalo-facultaire du CHU de Liège sous le numéro : 2015/48. Chaque participante a signé un formulaire de consentement éclairé quant à sa participation à l’étude ainsi qu’à l’autorisation de diffuser les résultats de façon confidentielle. Résultats : Les besoins des mères après leur accouchement ont été classés en 4 grandes catégories : le besoin d’information, le besoin de soutien psychologique, le besoin de partage d’expériences et le besoin de support matériel et pratique. Les femmes ne se sentent pas assez informées dans cette période de vie difficile. Elles ne se sentent pas non plus assez soutenues au point de vue psychologique mais également dans les tâches ménagères. Elles sont souvent fatiguées et se posent beaucoup de questions. Elles ont besoin de partager cette expérience de vie et elles ont besoin d’être rassurées et de se sentir comprises. Il semblerait qu’il y ait des différences de vécu d’expériences entre les mères et les professionnels mais également entre les mères et les pères. Conclusion : L’arrivée d’un bébé est une étape importante dans la vie d’une femme et d’un couple. Cela demande un remaniement tant sur les plans physique que psychologique et social. Les mères semblent ressentir un manque de support à différents niveaux au cours de la période postnatale. Cette étude procure des pistes pour répondre à leurs besoins et tenter de prévenir le risque de détresse psychologique dans la période postnatale. [less ▲]

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See detailQuelle est la place d’internet pour combler le besoin d’information des nouvelles mères ?
Slomian, Justine ULg; Bruyère, Olivier ULg; Reginster, Jean-Yves ULg et al

Poster (2016, May)

Contexte de l’étude : Les femmes autour de la grossesse et de la naissance expriment un besoin d’information. Internet est devenu l’un des moyens les plus importants de s’informer sur sa santé. De ... [more ▼]

Contexte de l’étude : Les femmes autour de la grossesse et de la naissance expriment un besoin d’information. Internet est devenu l’un des moyens les plus importants de s’informer sur sa santé. De nombreuses innovations dans la santé mobile révolutionnent les soins de santé actuels. Ces outils constituent une aide pour les médecins et permettent également de responsabiliser les patients par rapport à leur santé. Objectifs : Le but de cette étude est d’évaluer, chez des femmes francophones ayant des enfants de 0 à 2 ans, utilisant déjà internet, l’intérêt et le degré d’utilisation d’Internet pour des questions relatives à la période postnatale ; que cela concerne leur propre santé où celle de leur enfant. Méthode : Un sondage en ligne a été créé et diffusé largement via les réseaux sociaux. Toutes les femmes comprenant le français pouvait y répondre peu importe leur pays de résidence. Règles éthiques : L’étude a été approuvée par le comité d’éthique hospitalo-facultaire du CHU de Liège sous le numéro : 2013/254. La première page du questionnaire consistait en une explication de l’étude. La participation à l’enquête étant libre, nous avons donc considéré celle-ci comme le consentement du répondant. Résultats : 507 femmes ont répondu à ce sondage (8 femmes ont dû être éliminées de l’échantillon : 6 car le dernier enfant avait minimum 3 ans et 2 parce qu’elles étaient enceintes) : 74,5% des femmes habitaient en Belgique, 23,6% en France et 1,8% de pays divers (Canada, Luxembourg, Burkina Faso, Nouvelle Calédonie, Tunisie). Leur moyenne d’âge était de 30,5 ± 4,25 ans et 54,6% étaient des primipares. Parmi ces femmes, 90,2% ont utilisé internet pour répondre à des questions relatives à la période postnatale concernant leur enfant (82,3%) et/ou leur propre santé (71,3%). Ces femmes recherchent souvent des informations concernant l’allaitement maternel (75,2%), les aliments à introduire dans l’alimentation de l’enfant (62,1%), les dents (48,3%), les pics de croissance de l’enfant (43,4%), les petits boutons que les enfants peuvent présenter (38,2%), leur sexualité (30,7%) ou encore leur perte de poids (24,4%). Elles recherchent également des informations (23,3%) sur des questions plus « ponctuelles » de situation de la vie de tous les jours (ex : douleur de césarienne, sommeil de l’enfant, dépression postnatale, ...). Les raisons de ces recherches sont diverses mais les trois plus courantes sont le fait de vouloir trouver l’information par soi-même (87,3%), trouver des informations sur des symptômes présentés par l’enfant (79,6%) et compléter les informations fournies par un professionnels de la santé (65,2%). La majorité des femmes (90,9%) disent ne pas avoir un site unique de référence et recherche les informations sur différents sites. Beaucoup (81,1%) pensent que les professionnels de santé devraient suggérer des sites internet adaptés aux nouvelles mamans dans lesquels elles pourraient trouver des informations utiles pour leur post-partum et leur enfant. Les informations trouvées sur internet sembleraient avoir influencé la façon dont les femmes pensaient gérer leur enfant dans 51,8% des cas. Malgré qu’elles jugent que les informations qu’elles trouvent sur internet leur sont plutôt utiles (84,3%), elles n’attribuent qu’une note moyenne de 5,28 ± 1,68/10 quant à la qualité des informations qu’elles trouvent sur internet. Conclusion : Il existe un grand besoin d’information durant la période postnatale. Internet semblerait être une solution largement utilisée par les femmes pour combler ce besoin bien qu’elles ne semblent pas toujours satisfaites de la qualité des informations qu’elles y trouvent. Un site internet centralisé et contrôlé pourrait constituer une piste de solution à exploiter. [less ▲]

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See detailPrevalence of concomitant bone and muscle wasting in patients from the SarcoPhAge study.
Locquet, Médéa ULg; Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg et al

in Osteoporosis International (2016, April), 27(supplement 1), 129

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See detailIl n'est jamais trop tard pour apprendre à (bien) lire ... Les essais croisés
Slomian, Justine ULg; Bruyère, Olivier ULg

in Vaisseaux, Coeur, Poumons (2016), 21(9), 34-36

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See detailPrevalence of concomitant bone and muscle wasting in elderly women from the SarcoPhAge cohort: preliminary results
Locquet, Médéa ULg; Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg et al

in Journal of Frailty & Aging (2016)

Background: Recent studies suggest that bone and muscle wasting are closely interconnected. Objective: The aim was of this study is to assess the prevalence of osteoporosis in a population of women ... [more ▼]

Background: Recent studies suggest that bone and muscle wasting are closely interconnected. Objective: The aim was of this study is to assess the prevalence of osteoporosis in a population of women diagnosed with sarcopenia. Participants, setting and design: We analyzed cross-sectional data of women, aged 65 years and above, for whom bone mineral density was available at the time of inclusion in the SarcoPhAge (Sarcopenia and Physical impairment with advancing Age) cohort, an ongoing prospective study with the aim to assess consequences of sarcopenia. Measurements: Muscle strength was evaluated with a hydraulic hand-dynamometer, appendicular lean mass and bone mineral density by Dual-Energy X-Ray Absorptiometry and physical performance by the Short Physical Performance Battery test (SPPB). Sarcopenia was diagnosed according to the European Working Group on Sarcopenia in Older People definition, i.e. a low muscle mass plus either low muscle strength or low physical performance. A bone mineral density T-score equal to or below -2.5SD at the lumbar spine, at the total hip or at the femoral neck was used to define osteoporosis (World Health Organization definition). Results: A total of 126 women aged 74.38±6.32 years were included. Among them, 26 were assessed with sarcopenia (20.6%) and 34 (27.0%) with osteoporosis. There were more osteoporotic women among sarcopenic subjects (46.1%) than among non-sarcopenic subjects (22.0%) (p-value=0.011). A significant lower appendicular lean mass index was observed in osteoporotic women (p-value=0.025). We also observed, in osteoporotic subjects, a lower muscle strength (p-value=0.023). Numerical values of bone mineral density were lower in the sarcopenic population but the differences did not reach the level of statistical significance. Conclusion: Our study demonstrated that muscle mass and strength are lower in patients with osteoporosis. Prospective changes in bone and muscle mass will be investigated during the follow-up of our cohort. [less ▲]

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See detailPrevalence of concomitant bone and muscle wasting in patients from the SarcoPhAge Study
Locquet, Médéa ULg; Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg et al

in Journal of Frailty & Aging (2016), 5(Supplement 1), 84

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See detailQuality of life and physical components linked to sarcopenia: baseline data of the SarcoPhAge study
Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg; Petermans, Jean ULg et al

in European Geriatric Medicine (2015, September), 6S1

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See detailConcordance between muscle mass assessed by bioelectrical impedance analysis and by dual energy X-ray absorptionmetry among elderly people: a cross-sectional study
Buckinx, Fanny ULg; Reginster, Jean-Yves ULg; Dardenne, Nadia ULg et al

in BMC Musculoskeletal Disorders (2015), 16(1), 60-67

BACKGROUND: Besides magnetic resonance imaging, dual energy X-ray absorptiometry (DXA) seems the most reliable tool to evaluate body composition and is often considered as the gold standard in clinical ... [more ▼]

BACKGROUND: Besides magnetic resonance imaging, dual energy X-ray absorptiometry (DXA) seems the most reliable tool to evaluate body composition and is often considered as the gold standard in clinical practice. Bioelectrical impedance analysis (BIA) could provide a simpler, portative, and less expensive alternative. Because the body composition assessment by BIA is device-dependent, the aim of this study was to appraise the concordance between the specific bioelectrical impedance device InBody S10 and DXA for the body composition evaluation. METHODS: Body composition, included appendicular lean mass divided by height squared (ALM/ht2) was measured by DXA (Hologic QDR Discovery device) and by BIA (InBody S10 Biospace device). Agreement between tools was assessed by means of the Bland Altman method and reliability was determined using the IntraClass Coefficient (ICC). ICC was also computed to assess the reliability of the test-retest performed by the same operator or by two different ones. RESULTS: A total of 219 subjects were enrolled in this study (mean age: 43.7 +/- 19.1 years old, 51.6% of women). For the ALM/ht2, reliability of the test-retest of the BIA was high with an ICC of 0.89 (95%CI: 0.86-0.92) when performed by the same operator and an ICC of 0.77 (95%CI: 0.72-0.82) when performed by two different operators. Agreement between ALM/ht2 assessed by DXA and BIA was low (ICC = 0.37 (95%CI: 0.25-0.48)). Mean ALM/ht2 was 9.19 +/- 1.39 kg/m2 with BIA and 7.34 +/- 1.34 kg/m2 with DXA, (p < 0001). A formula developed using a multiple regression analysis, and taking into account muscle mass assessed by BIA, as well as sex and body mass index, explains 89% of the ALM/ht2 assessed by DXA. CONCLUSIONS: Although our results show that the measure of ALM/ht2 by BIA is reliable, the agreement between DXA and BIA is low. Indeed, BIA seems to overestimate ALM/ht2 compared to DXA and, consequently, it is important to use an adapted formula to obtain measurement of the appendicular lean mass by BIA close to that measured by DXA. [less ▲]

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See detailClinical Trials Using Mobile Health Applications
Lo Presti, Melissa; Abraham, Mickey; Appelboom, Geoff et al

in Pharmaceutical Medicine (2015), 29(1), 17-25

Background Mobile health (mHealth) is a growing sector of technology used in clinical practice. With the ubiquity of this technology in today’s society, the promise it holds for use in medicine is vast ... [more ▼]

Background Mobile health (mHealth) is a growing sector of technology used in clinical practice. With the ubiquity of this technology in today’s society, the promise it holds for use in medicine is vast. Purpose To conduct a study examining the current research and clinical trials involving mHealth applications used by human participants worldwide. Design Wesearched the ClinicalTrials.gov database for all original trials examining the role of mHealth applications and their use internationally and in varying clinical settings. Results Fifty trials were included. Eighty-eight percent of included trials were initiated from 2012 to 2014, with only 20 % of all included trials currently completed. The overwhelming majority of trials originated from the USA and other Western or European countries. There was a broad distribution of the trials with regard to study focus and purpose, involving applications in behaviour change, treatment adherence, diagnosis, disease management and patient-reported outcomes. Most included trials were performed in the setting of chronic diseases. Conclusion Use of mHealth applications is a growing field with broad implications and indications in clinical practice. This trend of increasing trials, studies and pervasiveness of technology in health care is a more recent development. Evidence in support of this technology is unclear from the trials included in this study; however, mHealth applications, devices and technology most assuredly have a role in chronic disease management and work to improve patient engagement. [less ▲]

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See detailEstimation of sarcopenia prevalence using various assessment tools
Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg; Slomian, Justine ULg et al

in Experimental Gerontology (2015), 61

BACKGROUND: Sarcopenia is defined as a progressive and generalized loss of muscle mass with either a loss of muscle strength or a loss of physical performance but there is no recommendation regarding the ... [more ▼]

BACKGROUND: Sarcopenia is defined as a progressive and generalized loss of muscle mass with either a loss of muscle strength or a loss of physical performance but there is no recommendation regarding the diagnostic tools that have to be used. In this study, we compared the prevalence of sarcopenia assessed using different diagnostic tools. METHODS: To measure muscle mass, muscle strength and physical performance, we used for each outcome two different diagnostic tools. For muscle mass, we used Dual Energy X-Ray Absorptiometry (DXA) and bio-electrical impedance analysis (BIA); for muscle strength, we used a hydraulic dynamometer and a pneumatic dynamometer; for physical performance we used the Short Physical Performance Battery test (SPPB test) and the walk speed. Eight diagnostic groups were hereby established. RESULTS: A total of 250 consecutive subjects were recruited in an outpatient clinic in Liège, Belgium. Estimated prevalence of sarcopenia varied from 8.4% to 27.6% depending on the method of diagnosis used. Regarding muscle mass, BIA systematically overestimated muscle mass compared to DXA (mean estimated prevalence with BIA=12.8%; mean prevalence with DXA=21%). For muscle strength, the pneumatic dynamometer diagnosed twice more sarcopenic subjects than the hydraulic dynamometer (mean estimated prevalence with PD=22.4%; mean estimated prevalence with HD=11.4%). Finally, no difference in prevalence was observed when the walking speed or the SPPB test was used. A weak overall kappa coefficient was observed (0.53), suggesting that the 8 methods of diagnosis are moderately concordant. CONCLUSION: Within the same definition of sarcopenia, prevalence of sarcopenia is highly dependent on the diagnostic tools used. [less ▲]

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See detailIs there a specific pattern of lean/fat mass ratio in sarcopenic subjects?
Beaudart, Charlotte ULg; Reginster, Jean-Yves ULg; Croisier, Jean-Louis ULg et al

in Journal of Frailty & Aging (2015), 4(S1), 61

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See detailOstéoporose et Médecine Personnalisée
Reginster, Jean-Yves ULg; NEUPREZ, Audrey ULg; LECART, Marie-Paule ULg et al

in Revue Médicale de Liège (2015), 70(5-6), 321-324

Osteoporosis is at the very early stages of the implementation of personalized medicine. However, the development of FRAX®, an algorithm offering the opportunity to calculate, in an individual patient ... [more ▼]

Osteoporosis is at the very early stages of the implementation of personalized medicine. However, the development of FRAX®, an algorithm offering the opportunity to calculate, in an individual patient, his/her 10-year fracture risk improves the decision process on the appropriateness to initiate a pharmacological treatment. This algorithm helps the physician to select drugs which are active on non-vertebral fractures only in high risk patients. Taking into consideration patients’ preferences, when selecting a therapeutic option, will improve long term adherence and subsequently efficacy and efficiency of the treatments. Attempts to define the natural course of osteoporosis or the response to therapy in individual patients by assessing their genetic profile remains, so far, inconclusive. [less ▲]

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