Hypovitaminosis D and osteoporosis in burn patients: are the current practices enough ?

in Osteoporosis International (2013), 24(Suppl 1), 377

Clinical sedation and bispectral index in burn children receiving gamma-hydroxybutyrate.

in Paediatric Anaesthesia (2012), 22(8), 799-804

Background:  Gamma-hydroxybutyrate (GHB) may be an interesting hypnotic agent in burn patients because of its good respiratory or hemodynamic tolerance. However, its clinical and electroencephalographic ... [more ▼]

Background:  Gamma-hydroxybutyrate (GHB) may be an interesting hypnotic agent in burn patients because of its good respiratory or hemodynamic tolerance. However, its clinical and electroencephalographic (EEG) sedative effects are not yet described in children. The aim of this prospective and randomized study was to assess clinical and EEG effects of increasing intravenous (IV) doses of GHB in burn children requiring sedation for burn wound cares. Methods:  Thirty six children hospitalized in a burn care unit were included and randomly assigned into three groups (G) according to the single IV dose of GHB they received before burn wound care: 10 mg·kg(-1) in G10, 25 mg·kg(-1) in G25, or 50 mg·kg(-1) in G50. All patients received oral premedication (morphine and hydroxyzine) 30 min before GHB injection. Respiratory rate, heart rate, pulse oximetry, and bispectral index (BIS) were continuously monitored. Depth of sedation was clinically assessed using Observer's Assessment of Alertness and Sedation (OAAS) Score, every 2 min until recovery (i.e., OAAS = 4). Results:  Median age was 17.5 [12-34] months. Whatever the dose, BIS decreased after IV GHB. Nadir value of BIS was significantly lower in G25 and G50 than in G10, as was for OAAS score. Nadir values were reached after same delays in G25 and G50. Duration of sedation was dose-dependant. Conclusion:  Bispectral index decreased after GHB injection and was correlated with OAAS score. Deep sedation can be safely achieved with IV doses of 25 or 50 mg·kg(-1) , but the last dose was associated with prolonged duration of clinical sedation. [less ▲]

Insuffisance respiratoire après électrisation par haute tension : évaluation quantitative

Poster (2012, June)

Evaluation quantitative de la réanimation volémique chez l'enfant brûlé : étude rétrospective.

Conference (2011, June)

Quantitative evaluation of fluid resuscitation in burn children : a retrospective study.

in Burns : Journal of the International Society for Burn Injuries (2011), 37(suppl 1), 12

Sédation par gamma-hydroxybutyrate et effets sur l'indice bispectral chez l'enfant.

Conference (2010, September)

L'anesthésiste et l'enfant brûlé.

Scientific conference (2009, March)

L'infusion intraveineuse de lidocaine réduit les besoins en propofol lors d'une AIVOC associant remifentanil et propofol.

in Annales Françaises d'Anesthésie et de Réanimation (2006), 25

Utilisation du MEOPA en pédiatrie

Poster (2004, March)

L'image du mois. Sous le pont myocardique coule la coronaire.

in Revue Médicale de Liège (2003), 58(10), 601-604