![]() Evaluation thérapeutique précoce par tomographie à émission de positronsJerusalem, Guy ; Beguin, Yves ; Fassotte, Marie-France et alin Médecine et Hygiène (2000), 58 Detailed reference viewed: 5 (0 ULg) Clinical PET in oncology; ; Bury, Thierry et alin Radioactive Isotopes in Clinical Medicine Research XXII (1997) Detailed reference viewed: 7 (4 ULg)![]() Tomographie a émission de positons dans l'évaluation de l'extension ganglionnaire intrathoracique du cancer bronchique non petites cellules. Etude préliminaire chez 30 patientsBURY, Thierry ; CORHAY, Jean-Louis ; et alin Revue des Maladies Respiratoires (1996), 13(3), 281-6 Current methods for evaluating the mediastinum include chest radiography, computed tomography (CT) or magnetic resonance (MR) imaging and mediastinoscopy. Despite advances in morphologic imaging, some ... [more ▼] Current methods for evaluating the mediastinum include chest radiography, computed tomography (CT) or magnetic resonance (MR) imaging and mediastinoscopy. Despite advances in morphologic imaging, some lung cancer patients are found to have unresectable disease at surgery. In contrast to CT scan or MR imaging, which depend primarily on anatomic and morphological criteria, positron emission tomography (PET) with 18fluorodeoxyglucose (FDG) depends mainly of the metabolic characteristics of a tissue for the diagnosis of disease. We perform a prospective study to compare FDG-PET and CT of the thorax in the presurgical assessment of the mediastinum in patients with newly diagnosed non-small cell lung cancer. Thirty patients have been included. CT and PET-scans were interpreted separately and results were compared to surgical staging during thoracotomy. In assessing mediastinal involvement, CT scan had a sensitivity of 56% and a specificity of 64%. For diagnosis mediastinal nodal disease, FDG-PET was 87% sensitive and 78% specific. Its positive predictive value was 82%, and the negative value was 83%. In conclusion, our preliminary results show that FDG-PET appears more accurate than CT in staging of mediastinal non-small cell lung cancer. [less ▲] Detailed reference viewed: 6 (1 ULg) Evaluation of the Solitary Pulmonary Nodule by Positron Emission Tomography ImagingBURY, Thierry ; ; et alin European Respiratory Journal (1996), 9(3), 410-4 Current noninvasive imaging methods are not sufficiently reliable for accurate detection of malignancy in most solitary pulmonary nodules (SPNs). Positron emission tomography (PET) using 18 ... [more ▼] Current noninvasive imaging methods are not sufficiently reliable for accurate detection of malignancy in most solitary pulmonary nodules (SPNs). Positron emission tomography (PET) using 18-fluorodeoxyglucose (FDG), showing increased FDG uptake and retention in malignant cells, has proved useful to differentiate malignant from benign tissue and could, therefore, contribute to the evaluation of the SPN. We performed a prospective study of 50 patients referred to the Pneumology Department with unclear diagnoses of SPN after conventional radiological screening. PET study was performed on each subject before an invasive procedure was proposed. Thirty three patients had a malignant nodule and 17 had a benign nodule. The mean size of malignant nodule was 3 cm (range 1.5-4.5 cm). All showed a marked increase in 18-FDG uptake. The mean size of benign nodule was 1.8 cm (range 0.5-3.5 cm). PET imaging showed the absence of 18-FDG uptake and correctly identified 15 of 17 benign nodules. There was two false-positive cases with a moderate increase in 18-FDG uptake (1 postprimary tuberculosis; and 1 anthracosilicotic nodule with nonspecific inflammation). At present, the sensitivity and specificity of the method are 100 and 88%, respectively. The positive and negative predictive values of PET imaging for SPNs are 94 and 100%, respectively. Our preliminary results demonstrate that PET-FDG imaging is a noninvasive technique, which appears highly accurate in differentiating malignant SPN from benign SPN. [less ▲] Detailed reference viewed: 8 (1 ULg)![]() Experimental acute spinal cord injury in rats : behavioural and histopathological analyses. Morphological studies on autologous transplants of cultured, adult DRG-derived Schwann cells to the injured spinal cord in adult ratsMartin, Didier ; ; Schoenen, Jean et alConference (1990, September) Detailed reference viewed: 9 (5 ULg) Viabilité myocardique après infarctus du myocarde traité par fibrinolyse: évaluation directe par tomographie à émission de positons combinant une étude régionale de la perfusion et de la captation glucidique; ; Pierard, Luc et alPoster (1987, September) Detailed reference viewed: 27 (5 ULg)![]() Thrombolysis in anterior myocardial infarction: effect on regional viability studied with positon emission tomography; ; Pierard, Luc et alin Circulation (1987), 76(suppl.IV), 5 Detailed reference viewed: 5 (1 ULg) Infarct size estimates from myocardial thallium and phosphate scans. prognostic implications; ; et al Poster (1980, March) Detailed reference viewed: 3 (0 ULg) |
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