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See detailThe COSPIX mission: focusing on the energetic and obscured Universe
Ferrando, P.; Goldwurm, A.; Laurent, P. et al

in Rieger, F.; van Eldik, C. (Eds.) 25th Texas Symposium on Relativistic Astrophysics (2011, April 01)

Tracing the formation and evolution of all supermassive black holes, including the obscured ones, understanding how black holes influence their surroundings and how matter behaves under extreme conditions ... [more ▼]

Tracing the formation and evolution of all supermassive black holes, including the obscured ones, understanding how black holes influence their surroundings and how matter behaves under extreme conditions, are recognized as key science objectives to be addressed by the next generation of instruments. These are the main goals of the COSPIX proposal, made to ESA in December 2010 in the context of its call for selection of the M3 mission. In addition, COSPIX, will also provide key measurements on the non thermal Universe, particularly in relation to the question of the acceleration of particles, as well as on many other fundamental questions as for example the energetic particle content of clusters of galaxies. COSPIX is proposed as an observatory operating from 0.3 to more than 100 keV. The payload features a single long focal length focusing telescope offering an effective area close to ten times larger than any scheduled focusing mission at 30 keV, an angular resolution better than 20 arcseconds in hard X-rays, and polarimetric capabilities within the same focal plane instrumentation. In this paper, we describe the science objectives of the mission, its baseline design, and its performances, as proposed to ESA. [less ▲]

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See detailUnrelated cord blood transplantation in adults with myelodysplasia or secondary acute myeloblastic leukemia : a survey on behalf of Eurocord and CLWP of EBMT
Robin, M.; Sanz, G. F.; Ionescu, I. et al

in Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K (2011), 25

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See detailKIR-ligand incompatibility in the Graft-versus-host direction improves outcome after umbilical cord blood transplantation for acute leukemia
Willemze, R.; Rodrigues, C. A.; Labopin, M. et al

in Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K (2009), 23

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See detailOn the nature of the hard X-ray source IGR J2018+4043
Bykov, Andrei Mikhailovich; Krassilchtchikov, Alexandre Mikhailovich; Uvarov, Yuri Alexandrovich et al

in Astrophysical Journal (2006), 649(1, Part 2), 21-24

We found a very likely counterpart to the recently discovered hard X-ray source IGR J2018 + 4043 in the multiwavelength observations of the source field. The source, originally discovered in the 20-40 keV ... [more ▼]

We found a very likely counterpart to the recently discovered hard X-ray source IGR J2018 + 4043 in the multiwavelength observations of the source field. The source, originally discovered in the 20-40 keV band, is now confidently detected also in the 40-80 keV band, with a flux of (1.4 +/- 0.4) x 10(-11) ergs cm(-2) s(-1). A 5 ks Swift observation of the IGR J2018 + 4043 field revealed a hard pointlike source with an observed 0.5-10 keV flux of 3.4(-0.8)(+0.7) x 10(-12) ergs cm(-2) s(-1) (90% confidence level) at alpha = 20(h)18(m)38(s).55, delta = +40 degrees 41'00.4" (with a 4".2 uncertainty). The combined Swift-INTEGRAL spectrum can be described by an absorbed power-law model with photon index Gamma = 1.3 +/- 0.2 and N-H = 6.1(-2.2)(+3.3) x 10(22) cm(-2). In archival optical and infrared data we found a slightly extended and highly absorbed object at the Swift source position. There is also an extended VLA 1.4 GHz source peaked at a beamwidth distance from the optical and X-ray positions. The observed morphology and multiwavelength spectra of IGR J2018 + 4043 are consistent with those expected for an obscured accreting object, i.e., an AGN or a Galactic X-ray binary. The identification suggests possible connection of IGR J2018 + 4043 to the bright gamma-ray source GEV J2020 + 4023 detected by COS B and CGRO EGRET. [less ▲]

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See detailINTEGRAL detection of hard X-rays from NGC 6334: nonthermal emission from colliding winds or an AGN?
Bykov, A. M.; Krassilchtchikov, A. M.; Uvarov, Y. A. et al

in Astronomy and Astrophysics (2006), 449(3), 917-923

Aims. We report the detection of hard X-ray emission from the field of the star-forming region NGC 6334 with the International Gamma-Ray Astrophysics Laboratory INTEGRAL. Methods. The JEM-X monitor and ... [more ▼]

Aims. We report the detection of hard X-ray emission from the field of the star-forming region NGC 6334 with the International Gamma-Ray Astrophysics Laboratory INTEGRAL. Methods. The JEM-X monitor and ISGRI imager aboard INTEGRAL and Chandra ACIS imager were used to construct 3-80 keV images and spectra of NGC 6334. Results. The 3-10 keV and 10-35 keV images made with JEM-X show a complex structure of extended emission from NGC 6334. The ISGRI source detected in the energy ranges 20-40 keV, 40-80 keV, and 20-60 keV coincides with the NGC 6334 ridge. The 20-60 keV flux from the source is (1.8 +/- 0.37) x 10(-11) erg cm(-2) s(-1). Spectral analysis of the source revealed a hard power-law component with a photon index about 1. The observed X-ray fluxes are in agreement with extrapolations of X-ray imaging observations of NGC 6334 by Chandra ACIS and ASCAGIS. Conclusions. The X-ray data are consistent with two very different physical models. A probable scenario is emission from a heavily absorbed, compact and hard Chandra source that is associated with the AGN candidate radio source NGC 6334B. Another possible model is the extended Chandra source of nonthermal emission from NGC 6334 that can also account for the hard X-ray emission observed by INTEGRAL. The origin of the emission in this scenario is due to electron acceleration in energetic outflows from massive early type stars. The possibility of emission from a young supernova remnant, as suggested by earlier infrared observations of NGC 6334, is constrained by the non-detection of Ti-44 lines. [less ▲]

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