References of "Remacle, Jean-Michel"
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See detailEffect of Multicolumn Lead Spinal Cord Stimulation on Low Back Pain in Failed Back Surgery Patients: A Three-Year Follow-Up
Remacle, Thibault ULiege; BONHOMME, Vincent ULiege; Renwart, Henri-Jean et al

in Neuromodulation (2017)

OBJECTIVES:Spinal cord stimulation (SCS) remains poorly efficient at reducing back pain in failed back surgery syndrome (FBSS) patients. We aimed at determining whether a new multicolumn lead SCS ... [more ▼]

OBJECTIVES:Spinal cord stimulation (SCS) remains poorly efficient at reducing back pain in failed back surgery syndrome (FBSS) patients. We aimed at determining whether a new multicolumn lead SCS technique was efficient at durably reducing their leg (LP) and back (BP) pain. MATERIALS AND METHODS:Sixty-two consecutive refractory FBSS patients received multicolumn SCS. Visual analogue scale (VAS) self-evaluation of BP, LP, and limitation of daily activity (LAD) were recorded preoperatively and at 2, 6, 12, 24, and 36 months after surgery. Quality of sleep and use of concomitant medications were also recorded. RESULTS:Complete datasets were obtained in 29 patients. BP (median VAS [25-75 centiles]) significantly decreased from 9 (8.5-10) preoperatively, to 3 (3-4) at short-term follow-up (2 months), and rose up to 5 (4-5) at 36 months. LP evolved from 7 (6-8) preoperatively, to 2.5 (2-3) at short-term follow-up, and 3 (2-3) at 36 months. Correspondingly, LAD VAS was 8 (8-9) preoperatively, and decreased to stable values of 3 (3-4) during the follow-up period. Quality of sleep also improved, with 72% of patients reporting poor sleep preoperatively to 0-7% in the follow-up period until 36 months. The percentages of patients regularly taking analgesic and/or co-analgesic medications decreased from 100% preoperatively to 8, 4, 12, 19, and 19%. CONCLUSION:Multicolumn lead SCS in FBSS patients significantly improve BP, LP, quality of life, and medication consumption for at least 36 months. A classical placebo effect cannot account for long-term improvements of such magnitude. [less ▲]

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See detailSustained effeciveness of occipital nerve stimulation in drug-resistant chronic cluster headache
MAGIS, Delphine ULiege; Gerardy, Pierre-Yves; Remacle, Jean-Michel et al

in Headache (2011)

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See detailSustained efficacy of occipital nerve stimulation in drug-resistant chronic cluster headache after up to 5 years treatment
Magis, Delphine ULiege; Gérardy, Pierre-Yves; Remacle, Jean-Michel et al

in Journal of Headache and Pain (2010), 11(Suppl 1), 15

Background. Drug-resistant chronic cluster headache (drCCH) is a devastating condition for which various invasive procedures have been tempted without any satisfactory effect. Our prospective pilot study ... [more ▼]

Background. Drug-resistant chronic cluster headache (drCCH) is a devastating condition for which various invasive procedures have been tempted without any satisfactory effect. Our prospective pilot study of great occipital nerve stimulation (ONS) in 8 drCCH patients showed encouraging results at 15 months (1). Methods. We recruited 15 patients with drCCH according to the previously published criteria of intractability (2). They were implanted with suboccipital stimulators on the side of their headache. Long-term follow-up was achieved by questionnaires administered during a headache consultation and/or by telephone interviews. Results. One patient had an immediate post operative infection of the material. Mean time with ONS was 28.8 months (range 3-60 months). Nine of the 14 remaining patients were totally pain-free (64%), 2 patients had an improvement in frequency exceeding 90% and one patient a 89% amelioration. Two patients did not respond or described mild improvement. Intensity of residual attacks was not improved by ONS. Four patients (29%) were able to reduce their prophylaxis. Common technical problems were battery depletion (N=8/14, 57%) and material infection (N=3/15, 20%). Recurrent battery replacement (until 2/ year in one patient) is now avoided by the availability of rechargeable batteries. Clinical peculiarities associated with ONS were occurrence of infrequent contralateral attacks (N=5/14, 36%), and/or isolated ispilateral autonomic attacks (N=5/14, 36%). Rapid attack recurrence after stimulator switch off was reported by 7/12 improved patients (58%). Two patients found ONS-related paresthesias unbearable; one had his stimulator removed, the other switched it off though he was objectively ameliorated. Subjectively, nine patients are very satisfied by ONS and one patient moderately satisfied. Conclusions. Our long-term follow-up confirms the efficacy of ONS in drCCH, which remains a safe and well-tolerated technique. The occurrence of contralateral attacks and isolated autonomic attacks in nearly 50% of ONS responders may have therapeutic and pathophysiological implications. [less ▲]

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See detailOccipital nerve stimulation for drug-resistant chronic cluster headache: a prospective pilot study
Magis, Delphine ULiege; Allena, Marta; Bolla, Monica et al

in Lancet Neurology (2007), 6(4), 314-321

Background Drug-resistant chronic duster headache (drCCH) is a devastating disorder for which various destructive procedures have been tried unsuccessfully. Occipital nerve stimulation (ONS) is a new ... [more ▼]

Background Drug-resistant chronic duster headache (drCCH) is a devastating disorder for which various destructive procedures have been tried unsuccessfully. Occipital nerve stimulation (ONS) is a new, safe strategy for intractable headaches. We undertook a prospective pilot trial of ONS in drCCH to assess clinical efficacy and pain perception. Methods Eight patients with drCCH had a suboccipital neurostimulator implanted on the side of the headache and were asked to record details of frequency, intensity, and symptomatic treatment for their attacks in a diary before and after Continuous ONS. To detect changes in cephalic and extracephalic pain processing we measured electrical and pressure pain thresholds and the nociceptive blink reflex. Findings Two patients were pain free after a follow-up of 16 and 22 months; one of them still had occasional autonomic attacks. Three patients had around a 90% reduction in attack frequency. Two patients, one of whom had had the implant for only 3 months, had improvement of around 40%. Mean follow-up was 15.1 months (SD 9.5, range 3-22). Intensity of attacks tends to decrease earlier than frequency during ONS and, on average, is improved by 50% in remaining attacks. All but one patient were able to substantially reduce their preventive drug treatment. Interruption of ONS by switching off the stimulator or because of an empty battery was followed within days by recurrence and increase of attacks in all improved patients. ONS did not significantly modify pain thresholds. The amplitude of the nociceptive blink reflex increased with longer durations of ONS. There were no serious adverse events. Interpretation ONS could be an efficient treatment for drCCH and could be safer than deep hypothalamic stimulation. The delay of 2 months or more between implantation and significant clinical improvement suggests that the procedure ads via slow neuromodulatory processes at the level of upper brain stem or diencephalic centres. [less ▲]

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See detailOccipital nerve stimulation in refractory chronic cluster headache: a pilot study of efficacy and mechanisms in five patients.
MAGIS, Delphine ULiege; Allena, Marta; Vandenheede, Michel et al

in Cephalalgia : An International Journal of Headache (2005, October), 25

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