References of "Reginster, Marie-Annick"
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See detailCorneosurfametry and corneoxenometry.
PIERARD, Gérald ULg; Franchimont, Claudine ULg; REGINSTER, Marie-Annick ULg

in Berardesca, Enzo; Wilhelm, K.P.; Maibach, H.I. (Eds.) Non invasive diagnostic techniques in clinical dermatology. (2014)

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See detailEhlers-Danlos syndrome.
HERMANNS-LE THI KIM, Trinh ULg; REGINSTER, Marie-Annick ULg; Franchimont, Claudine ULg et al

in Stirling, J; Curry, A; Eyden, B (Eds.) Diagnostic electron microscopy (2013)

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See detailDermal ultrastructure in low Beighton score members of 17 families with hypermobile-type Ehlers-Danlos syndrome.
Hermanns-Le, Trinh ULg; REGINSTER, Marie-Annick ULg; Franchimont, Claudine ULg et al

in Journal of Biomedicine & Biotechnology (2012), 2012

The distinction between the Ehlers-Danlos syndrome hypermobile type (EDSH) and the benign joint hypermobility syndrome (BJHS) is unclear. The aim of the present study was to compare skin ultrastructural ... [more ▼]

The distinction between the Ehlers-Danlos syndrome hypermobile type (EDSH) and the benign joint hypermobility syndrome (BJHS) is unclear. The aim of the present study was to compare skin ultrastructural abnormalities of EDSH and BJHS among different families. Skin of 23 EDSH, 27 BJHS, and 41 asymptomatic subjects from 17 families was examined using transmission electron microscopy. Similar ultrastructural abnormalities were found irrespective of the Beighton score. Flower-like collagen fibrils represented the key change and elastic fibers were altered as well. Beighton score is a clinical parameter rating joint mobility that appeared unrelated to quantitative and qualitative collagen ultrastructural alterations in the skin. Some EDSH family members fit with BJHS diagnosis. BJHS possibly represents a mild variant of EDSH. [less ▲]

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See detailTélédermatopathologie et dermatopathologie virtuelle en temps réel.
REGINSTER, Marie-Annick ULg; Pierard, Sébastien ULg; PIERARD, Gérald ULg et al

in Dermatologie Actualité (2012), 129

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See detailSmouldering malignant melanoma and metastatic dormancy: an update and review.
PIERARD, Gérald ULg; PIERARD-FRANCHIMONT, Claudine ULg; REGINSTER, Marie-Annick ULg et al

in Dermatology Research and Practice (2012), 2012

The fund of knowledge regarding the versatility of presentation of MM metastases is still quite incomplete. The recent literature pertaining to the current understanding of the mechanisms underlying two ... [more ▼]

The fund of knowledge regarding the versatility of presentation of MM metastases is still quite incomplete. The recent literature pertaining to the current understanding of the mechanisms underlying two special features of MM metastasis is reviewed. On the one hand, a long disease-free interval (MM dormancy) may occur before the surge of overt metastases. On the other hand, the so-called MM smouldering phenomenon refers to the condition where regional metastases wax and wane for long periods of time on restricted skin regions. It is important to emphasize that local micrometastases often predict sentinel lymph node involvement but may not reflect progression of the primary MM to full-blown visceral metastatic competence. It is likely that a combination of factors impacts the versatile MM metastasic progression. Among the main factors, one has to mention the phenotypic heterogeneity and variability in the phenotype of MM cells, the presence of MM stem cells and MM cells engaged in an amplification proliferation pool, as well as the host immune response, and possibly the induction of a particular stromal structure and vascularity. [less ▲]

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See detailMolecular dermatopathology in malignant melanoma.
REGINSTER, Marie-Annick ULg; PIERARD-FRANCHIMONT, Claudine ULg; PIERARD, Gérald ULg et al

in Dermatology Research and Practice (2012), 2012(684032), 1-6

At present, immunohistochemistry is taken for granted in the establishment of malignant melanoma (MM) diagnosis. In recent years, molecular diagnosis in dermatopathology has benefited from a vast array of ... [more ▼]

At present, immunohistochemistry is taken for granted in the establishment of malignant melanoma (MM) diagnosis. In recent years, molecular diagnosis in dermatopathology has benefited from a vast array of advances in the fields of genomics and proteomics. Sensitive techniques are available for detecting specific DNA and RNA sequences by molecular hybridization. This paper intends to update methods of molecular cytogenetics available as diagnostic adjuncts in the field of MM. Cytogenetics has highlighted the pathogenesis of atypical melanocytic neoplasms with emphasis on the activation of the mitogen-activated protein kinase (MAPK) signalling pathway during the initiation step of the neoplasms. 20 to 40% of MM families have mutations in the tumour suppressor gene p16 or CDKN2A. In addition, somatic mutations in p16, p53, BRAF, and cKIT are present in MM. Genome-wide scan analyses on MM indicate positive associations for genes involved in melanocytic naevi, but MM is likely caused by a variety of common low-penetrance genes. Molecular dermatopathology is expanding, and its use in the assessment of melanocytic neoplasms appears to be promising in the fields of research and diagnosis. Molecular dermatopathology will probably make its way to an increased number of diagnostic laboratories. The expected benefit should improve the patient management. This evolution points to a need for evolution in the training requirements and role of dermatopathologists. [less ▲]

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See detailComment j'explore...le meli-melo des ichtyoses.
Hermanns-Le, Trinh ULg; REGINSTER, Marie-Annick ULg; QUATRESOOZ, Pascale ULg et al

in Revue Médicale de Liège (2011), 66(2), 102-8

Ichthyoses are hereditary and sometimes acquired diseases of keratinisation. They are heterogeneous according to their clinical and histopathological presentations, as well as to the nature of their ... [more ▼]

Ichthyoses are hereditary and sometimes acquired diseases of keratinisation. They are heterogeneous according to their clinical and histopathological presentations, as well as to the nature of their molecular and genetic alterations. We present the most frequent types of hereditary ichthyoses. [less ▲]

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See detailIntense pulsed-light therapy for proliferative superficial strawberry haemangiomas of infancy.
CAUCANAS, Marie ULg; PAQUET, Philippe ULg; HENRY, Frédérique ULg et al

in Case Reports in Dermatological Medicine (2011), 2011(art.253607), 1-5

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See detailL'image du mois. Necrobiose lipoidique.
Szepetiuk, Gregory; FRANCHIMONT, Claudine ULg; REGINSTER, Marie-Annick ULg et al

in Revue Médicale de Liège (2011), 66(2), 61-3

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See detailRevisiting cutaneous adverse reactions to pemetrexed
PIERARD-FRANCHIMONT, Claudine ULg; QUATRESOOZ, Pascale ULg; REGINSTER, Marie-Annick ULg et al

in Oncology Letters (2011), (2), 769-772

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See detailMicropapules paroxysmales prurigineuses tronculaires.
CAUCANAS, Marie ULg; PIERARD, Gérald ULg; FRANCHIMONT, Claudine ULg et al

in Dermatologie Actualité (2011), 127

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See detailLa peau du patient sous chimiothérapie anticancéreuse.
PIERARD, Gérald ULg; PAQUET, Philippe ULg; FRANCHIMONT, Claudine ULg et al

in Dermatologie Actualité (2011), 124

Des effets cutanés indésirables peuvent survenir lors de chimiothérapies anticancéreuses. La morbidité peut être handicapante à des degrés divers. Certaines manifestations sont graves comme celles ... [more ▼]

Des effets cutanés indésirables peuvent survenir lors de chimiothérapies anticancéreuses. La morbidité peut être handicapante à des degrés divers. Certaines manifestations sont graves comme celles rencontrées lors de nécroses épithéliales et/ou vasculaires étendues. D’autres sont spécifiques à l’agent administré. Tel est le cas pour des éruptions acnéiformes induites par les antagonistes de l’EGFR. Dans la grande majorité des cas, les altérations de la structure de la couche cornée et de ses fonctions se résument seulement à un état de xérose. Parfois aussi, les altérations ne se décèlent qu’à l’examen histopathologique sans répercussion clinique manifeste. Pour chaque patient concerné, il convient d’identifier avec précision les effets indésirables de la chimiothérapie anticancéreuse afin de choisir les moyens les plus adéquats pour prévenir leur aggravation et les traiter au mieux. L’apport de l’examen dermatopathologique standard et fonctionnel est précieux au stade du diagnostic. [less ▲]

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See detailImputabilite medicamenteuse dans les iatrogenies cutanees.
PIERARD-FRANCHIMONT, Claudine ULg; QUATRESOOZ, Pascale ULg; REGINSTER, Marie-Annick ULg et al

in Revue Médicale de Liège (2011), 66(9), 474-7

Drug eruptions are frequently encountered. Their putative diagnosis is based on a set of imputability arguments. The histopathological aspect is often evocative of the nature of the dermatosis. It varies ... [more ▼]

Drug eruptions are frequently encountered. Their putative diagnosis is based on a set of imputability arguments. The histopathological aspect is often evocative of the nature of the dermatosis. It varies according to the type of drug reaction. Some drug eruptions follow a benign course, but others are life-threatening. [less ▲]

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See detailLa maladie de Paget mammaire indicatrice d'un adenocarcinome sous-jacent.
REGINSTER, Marie-Annick ULg; QUATRESOOZ, Pascale ULg; PIERARD-FRANCHIMONT, Claudine ULg et al

in Revue Médicale de Liège (2011), 66(5-6), 265-8

Mammary Paget's disease is an intraepithelial carcinoma present on the nipple and its areola. The tumor typically develops in middle aged women. It is frequently associated or contiguous to an underlying ... [more ▼]

Mammary Paget's disease is an intraepithelial carcinoma present on the nipple and its areola. The tumor typically develops in middle aged women. It is frequently associated or contiguous to an underlying galactophoric adenocarcinoma. The histopathologic and immunopathologic aspects are typical and linked to the presence of Paget's cells. Early diagnosis is required searching for a possible underlying carcinoma. The surgical treatment is directed by the characteristics of the deep mammary carcinoma. [less ▲]

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See detailImagerie de la microcirculation cutanée défaillante.
QUATRESOOZ, Pascale ULg; REGINSTER, Marie-Annick ULg; FRANCHIMONT, Claudine ULg et al

in Dermatologie Actualité (2010), 123

Le réseau microvasculaire de la peau joue des rôles physiologiques majeurs en oxygénant les tissus et en permettant des échanges thermiques finement régulés. Son parcours résistif et capacitif module les ... [more ▼]

Le réseau microvasculaire de la peau joue des rôles physiologiques majeurs en oxygénant les tissus et en permettant des échanges thermiques finement régulés. Son parcours résistif et capacitif module les résistances périphériques au débit sanguin. La microvascularisation est sous l’influence de divers facteurs, mais globalement, elle semble presque immuable dans la peau saine. En revanche, certaines circonstances pathologiques engendrent des hyperplasies ou des hypoplasies vasculaires. Parfois aussi, le réseau semble garder son extension normale, mais sa structure intime est remaniée. Cette revue est un florilège d’aspects microscopiques associés à des perturbations majeures de la fonctionnalité vasculaire cutanée. [less ▲]

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See detailFacing towards epidermal stem cells (Review).
Schreder, Anelaure; Pierard, Gérald ULg; Paquet, Philippe ULg et al

in International Journal of Molecular Medicine (2010), 26(2), 171-4

Skin contains somatic stem cells that generate keratinocyte, melanocyte and mesenchymal cell lineages. These somatic stem cells have traditionally been thought to be restricted in their differentiation ... [more ▼]

Skin contains somatic stem cells that generate keratinocyte, melanocyte and mesenchymal cell lineages. These somatic stem cells have traditionally been thought to be restricted in their differentiation and regeneration potential to the tissues in which they reside. This review focused on epidermal stem cells (ESCs). These cells are distinguished from transitory amplifier cells and post-mitotic cells. ESC are found in the interadnexal epidermis and in the bulge region of hair follicles. A series of ESCs markers are available, but increased sensitivity and specificity require further development. [less ▲]

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See detailLe pilomatricome unique ou multifocal et son pendant malin.
Reginster, Marie-Annick ULg; Quatresooz, Pascale ULg; Franchimont, Claudine ULg et al

in Dermatologie Actualité (2010), 121

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