effects of cholecaciferol supplementation and optimized calcium intakes on vitamin D status, muscle strength and bone health: a one-year pilot randomized controlled trial in adults with severe burns
ROUSSEAU, Anne-Françoise ; FOIDART-DESSALLE, Marguerite ; LEDOUX, Didier et al
in Burns : Journal of the International Society for Burn Injuries (2015), 41(2), 317-325
Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess ... [more ▼]
Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess effects of a cholecalciferol (VD3) supplementation and an optimized calcium (Ca) regimen on vitamin D (VD) status, bone and muscle health during sequelar stage of burn injury. Design: Monocentric randomized controlled trial. Methods: Fifteen adults with thermal burns dating from 2 to 5 years were randomized into two groups. For 12 months, they either received a quarterly IM injection of 200,000 IU VD3 and daily oral Ca (Group D) or placebo (Group P). VD status and bone remodeling markers were assessed every 3 months. Knee muscle strength and bone mineral density were, respectively, assessed using isokinetic dynamometry and dual X-ray absorptiometry at initiation (M0) and completion (M12) of the protocol. Results: Of all the patients, 66% presented with VD deficiency and 53% (with 3 men <40 y) were considered osteopenic at inclusion. After one year, calcidiol levels significantly increased in Group D to reach 40 (37–61) ng/ml. No significant change in bone health was observed in both groups while Group D significantly improved quadriceps strength when tested at high velocity. Conclusions: This VD3 supplementation was safe and efficient to correct hypovitaminosis D in burn adults. When combined with optimized Ca intakes, it demonstrated positive effects on muscle health but not on bone health. A high prevalence of hypovitaminosis D and osteopenia in these patients, as well as their wide range of muscle performances, seem to be worrying when considering rehabilitation and quality of life. [less ▲]Detailed reference viewed: 30 (11 ULg)
Effect of optimized cholecalciferol and calcium intakes on bone mineral density: a randomized controlled trial in adult burns during sequelae stage.
ROUSSEAU, Anne-Françoise ; FOIDART-DESSALLE, Marguerite ; REMY, Christophe et al
in Nutrients (2014), 6Detailed reference viewed: 23 (7 ULg)
La prise en charge précoce du patient brûlé en kinésithérapie.
REMY, Christophe ; JACQUEMIN, Denise ; MASSAGE, Patrick et al
in Réanimation (2013), 22(5), 543-551
Profonde ou atteignant une large surface cutanée, la brûlure engendre souvent des séquelles fonctionnelles impor- tantes. Ces séquelles se constituent précocement et ont des répercussions non négligeables ... [more ▼]
Profonde ou atteignant une large surface cutanée, la brûlure engendre souvent des séquelles fonctionnelles impor- tantes. Ces séquelles se constituent précocement et ont des répercussions non négligeables sur la qualité de vie des patients. Pour les prévenir et les traiter, le kinésithérapeute est un acteur important dans leur prise en charge précoce. Il devra évaluer les fonctions respiratoires, musculaires, orthopédiques mais également cutanées. L’objectif est de définir des stratégies de traitement faisant appel à des techniques de kinésithérapie classiques adaptées à cette pathologie spécifique. [less ▲]Detailed reference viewed: 147 (52 ULg)
Insuffisance respiratoire après électrisation par haute tension : évaluation quantitative
REMY, Christophe ; KELLENS, Isabelle ; JACQUEMIN, Denise et al
Poster (2012, June)Detailed reference viewed: 54 (15 ULg)
How a topic treatment can worsen the situation: A new type of iatrogenic "burn".
REMY, Christophe ; ; MAGNETTE, André et al
Poster (2011, September 15)
Many studies showed the high frequency of cutaneous intolerances to ketoprofen but in 85 percent of them, these are photoallergies. The Belgian dematologists published an article a few years ago ... [more ▼]
Many studies showed the high frequency of cutaneous intolerances to ketoprofen but in 85 percent of them, these are photoallergies. The Belgian dematologists published an article a few years ago, demonstrating that it is important to avoid prescription of topical ketoprofen during sunny periods. Our experience showed the risks of lesions without exposing to UV radiations. These gels, on free sale, are widely used by the public. In physiotherapy, they are also regularly used by practitioners who rarely know the risk of photoallergies and often ignore the possibility of burn. In France, many questions have already been asked about these gels and they were even the object of a temporary withdrawal. [less ▲]Detailed reference viewed: 12 (0 ULg)