References of "Pire, G"
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See detailEconomic evaluation of an osteoporosis screening campaign: using FRAX as a prescreening tool
Hiligsmann, Mickaël ULg; Ben Sedrine, Wafa ULg; Bruyère, Olivier ULg et al

in Osteoporosis International (2014), 25(2), 38-39

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See detailAnalysis of the discriminant ability of shorter versions of the French ADAM questionnaire
Tancredi, Annalisa ULg; Legros, Jean-Jacques ULg; Pire, G. et al

in Aging Male : The Official Journal of the International Society for the Study of the Aging Male (2007), 10(3), 159-164

Objective. To investigate whether shorter versions of the ADAM test, a screening questionnaire for andropause, provide better diagnostic value than the original tool. Methods. Five thousand and twenty ... [more ▼]

Objective. To investigate whether shorter versions of the ADAM test, a screening questionnaire for andropause, provide better diagnostic value than the original tool. Methods. Five thousand and twenty-eight volunteer men aged 50-70 years attending a screening campaign for andropause, provided a fasting blood sample and completed the French ADAM test. Logistic regression analysis identified items that best predict andropause defined as serum free testosterone level below 70 ng/l. ROC curves assessed the diagnostic value of modified versions of the ADAM test, obtained by elimination of the less relevant predictors of andropause. Results. Only four items of the ADAM questionnaire may account for the diagnosis of andropause. These items concerned loss of height, decrease in libido and in enjoyment of life and deterioration in work performance. Item 9 was borderline significant. The area under the ROC curve for the short versions varied slightly from 0.555 to 0.560. As expected, model 6 has a greater specificity (56.02%) than the original tool while the efficiency increased slightly (54.85%). Conclusion. The modified versions of the ADAM test do not provide better diagnostic value than the original tool. Conclusion. The modified versions of the ADAM test do not provide better diagnostic value than the original tool. [less ▲]

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See detailContribution of MX dynamin, oligoadenylate synthetase, and protein kinase R to anti-paramyxovirus activity of type-1 interferons in vitro
Leroy, M.; Baise, Etienne ULg; Pire, G. et al

in American Journal of Veterinary Research (2007), 68

OBJECTIVE: To determine the contribution of MX dynamin, oligoadenylate synthetase (OAS), and double-stranded RNA-dependent protein kinase R (PKR) to the antiviral effects of type 1 interferons (IFNs ... [more ▼]

OBJECTIVE: To determine the contribution of MX dynamin, oligoadenylate synthetase (OAS), and double-stranded RNA-dependent protein kinase R (PKR) to the antiviral effects of type 1 interferons (IFNs) against bovine parainfluenza-3 virus (PI-3V) infection of Vero cells. SAMPLE POPULATION: Vero cell cultures. PROCEDURES: PI-3V yield was first compared between control and transfected type 1 IFNs-incompetent Vero cells expressing recombinant OAS or MX proteins. Afterwards, phosphorylation of eukaryotic initiation factor 2 alpha (eIF2alpha) was used to scale the degree of PKR activation upon infection of Vero cells by PI-3V. RESULTS: Overexpression of OAS did not result in significantly decreased viral replication. Phosphorylated eIF2alpha forms, the hallmark of PKR activation, were not increased in IFNalpha-primed infected Vero cells. Although human MXA contributed to partial blockade of replication of bovine PI-3V, the antiviral effect was not as strong as that of IFNalpha. CONCLUSIONS AND CLINICAL RELEVANCE: The powerful anti-Paramyxovirus activity of type 1 IFNs is mediated by noncanonic pathways. [less ▲]

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See detailSelf-reported versus measured prevalence of osteoporosis. An age-stratified analysis of its diagnostic coverage
Richy, Florent; Bruyère, Olivier ULg; Maassen, P. et al

in Osteoporosis International (2006, June), 17(Suppl.2), 45-46

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See detailSelf-reported versus measured prevalence of osteoporosis. An age-stratified analysis of its diagnostic coverage
Richy, Florent; Bruyère, Olivier ULg; Maassen, P. et al

in Osteoporosis International (2006, March), 17(Suppl.1), 93-94

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See detailInterest of the androgen deficiency in aging males (ADAM) questionnaire for the identification of hypogonadism in elderly community-dwelling male volunteers
Tancredi, Annalisa ULg; Reginster, Jean-Yves ULg; Schleich, FLorence ULg et al

in European Journal of Endocrinology (2004), 151(3), 355-360

Objective: To date, serum free testosterone measurement is considered to be the gold standard for the diagnosis of hypogonadism in elderly males but it is not available to all subjects suspected of a ... [more ▼]

Objective: To date, serum free testosterone measurement is considered to be the gold standard for the diagnosis of hypogonadism in elderly males but it is not available to all subjects suspected of a decrease in testicular function. Therefore, we evaluated whether the Androgen Deficiency in Aging Males (ADAM) questionnaire, in its original or in a modified 'quantitative' version (qADAM), could be used as a surrogate to biochemical determinations for the identification of hypogonadism in elderly males. Methods: 5028 men, aged 50-70 years, spontaneously consulting for the assessment of their gonadal function were studied. ADAM and qADAM, allocating a value of 1 point for any positive answer to each of the 10 questions of the ADAM test, were assessed for their ability to discriminate between males with free testosterone levels below or above 70 ng/l. Results: The sensitivity and specificity of the ADAM score were 81% and 21.6% respectively. The use of ADAM resulted in an appropriate classification of our population in normal or hypogonadal subjects in 44.5% of the cases. The area under the receiver operating characteristics (ROC) curve for the qADAM (0.529) revealed a highly marginal interest of this quantitative approach compared with the original scoring system. Conclusions: The ADAM test has a high sensitivity to identify aging males with low free testosterone levels. However, due to its lack of specificity, this test cannot be used as a surrogate to serum free testosterone testing for the identification of androgen deficiency in elderly, community-dwelling males. [less ▲]

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See detailEvaluation of prevalence of osteoporosis and osteopenia in men presenting at multiple risk detection campaign
Hanssens, L. C.; De Ceulaer, F.; Tancredi, Annalisa ULg et al

in Osteoporosis International (2004, May), 15(Suppl.1), 54

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See detailEvaluation of the osteoporosis self-assessment tool (OST) as a screening test for osteoporosis and osteopenia in men
DeCeulaer, F.; Hanssens, L.; Tancredi, Annalisa ULg et al

in Osteoporosis International (2004, May), 15(Suppl.1), 54

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See detailEvaluation of the relationship between IGF-1, IGF-BP3, BMD and age in men presenting at a multiple risk detection campaign
Hanssens, L.; Tancredi, Annalisa ULg; DeCeulaer, F. et al

in Osteoporosis International (2004, May), 15(Suppl.1), 48-49

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See detailEvaluation of the relationship between IGF-I, IGF-BP3, BMD and age in men presenting at a multiple risk detection campaign
Hanssens, L.; Tancredi, Annalisa ULg; De Ceulaer, F. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 90-91

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See detailEvaluation of the osteoporosis self-assessment tool (OST) as a screening test for osteoporosis and osteopenia in men
De Ceulaer, F.; Hanssens, L.; Tancredi, Annalisa ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 93

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See detailEvaluation of prevalence of osteoporosis and osteopenia in men presenting at multiple risk detection campaign
Hanssens, L.; De Ceulaer, F.; Tancredi, Annalisa ULg et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 90

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See detailEvaluation of a campaign for osteoporosis screening in the general population: what is the follow-up given by general practitioners to a positive screening result?
Richy, Florent; Pire, G.; Maassen, P. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 67

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See detailEvaluation of an osteoporosis screening campaign in the general population: does misclassification by screening test impact on the perception of the campaign?
Richy, Florent; Pire, G.; Maassen, P. et al

in Osteoporosis International (2003, November), 14(Suppl. 7), 68

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