  Conservative Mutations In The Immunosuppressive Region Of The Bovine Leukemia Virus Transmembrane Protein Affect Fusion But Not Infectivity In Vivo; ; et al in Journal of Biological Chemistry (1998), 273(21), Detailed reference viewed: 5 (1 ULg)Common Prevalence Of Alanine And Glycine In Mobile Reactive Center Loops Of Serpins And Viral Fusion Peptides - Do Prions Possess A Fusion Peptide; ; Brasseur, Robert  et alin Journal of Computer-Aided Molecular Design (1994), 8(2), Serpin reactive centre loops and fusion peptides released by proteolytic cleavage are particularly mobile. Their amino acid compositions reveal a common and unusual abundance of alanine, accompanied by ... [more ▼] Serpin reactive centre loops and fusion peptides released by proteolytic cleavage are particularly mobile. Their amino acid compositions reveal a common and unusual abundance of alanine, accompanied by high levels of glycine. These two small residues, which are not simultaneously abundant in stable helices (standard or transmembrane), probably play an important role in mobility. Threonine and valine (also relatively small amino acids) are also abundant in these two kinds of peptides. Moreover, the known 3D structures of an uncleaved serpin reactive centre and a fusion peptide are strikingly similar. Such sequences possess many small residues and are found in several signal peptides and in PrP, a protein associated with spongiform encephalopathies and resembling virus envelope proteins. These properties may be related to the infection mechanisms of these diseases. [less ▲] Detailed reference viewed: 4 (2 ULg)Redox Mechanism For The Chaperone Activity Of Heat-Shock Proteins Hsp-60, Hsp-70 And Hsp-90 As Suggested By Hydrophobic Cluster-Analysis - Hypothesis; ; Portetelle, Daniel et alin Comptes Rendus de l'Académie des Sciences. Série III, Sciences de la Vie (1994), 317(8), Detailed reference viewed: 11 (3 ULg)Cloning And Characterization Of Mn, A Human Tumor-Associated Protein With A Domain Homologous To Carbonic-Anhydrase And A Putative Helix-Loop-Helix Dna-Binding Segment; ; et al in Oncogene (1994), 9(10), Detailed reference viewed: 47 (1 ULg)Functional Sites Of The Bovine Leukemia-Virus Envelope Glycoproteins Using Structural And Immunological Data; ; et al in Archives Internationales de Physiologie de Biochimie et de Biophysique (1994), 102(2), Detailed reference viewed: 4 (1 ULg)Identification Of Functional-Sites On Bovine Leukemia-Virus Envelope Glycoproteins Using Structural And Immunological Data; Portetelle, Daniel ; et alin European Journal of Biochemistry (1994), 222(2), Detailed reference viewed: 5 (1 ULg)The Bovine Leukemia-Virus (Blv) Envelope Glycoprotein Gp51 As A General-Model For The Design Of A Subunit Vaccine Against Retroviral Infection - Mapping Of Functional Sites Through Immunological And Structural Data; ; et al in Leukemia (1994), 8 Detailed reference viewed: 10 (1 ULg)Structural Similarities Between Chaperone Molecules Of The Hsp60 And Hsp70 Families Deduced From Hydrophobic Cluster-Analysis; ; Portetelle, Daniel et alin Febs Letters (1994), 342(3), Detailed reference viewed: 4 (1 ULg) |
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