References of "Menu, Eline"
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See detailMolecular mechanisms, current management and next generation therapy in myeloma bone disease.
Heusschen, Roy ULg; Muller, Joséphine ULg; Duray, Elodie ULg et al

in Leukemia & Lymphoma (2017)

Multiple myeloma (MM) bone disease is a major cause of morbidity and mortality in MM patients and persists even in patients in remission. This bone disease is caused by an uncoupling of bone remodeling ... [more ▼]

Multiple myeloma (MM) bone disease is a major cause of morbidity and mortality in MM patients and persists even in patients in remission. This bone disease is caused by an uncoupling of bone remodeling, with increased osteoclast and decreased osteoblast activity and formation, culminating in lytic bone destruction. Bisphosphonates are the current standard of care but new therapies are needed. As the molecular mechanisms controlling MM bone disease are increasingly well understood, new therapeutic targets are extensively explored in the preclinical setting and initial clinical trials with novel compounds now show promising results. In this review, we will provide a comprehensive overview of the biology of MM bone disease, summarize its current clinical management and discuss preclinical and clinical data on next generation therapies. [less ▲]

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See detailThe effects of forodesine in murine and human multiple myeloma cells
Bieghs, Liesbeth; Caers, Jo ULg; De Bruyne, Elke et al

in Advances in Hematology (2010)

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See detailThymosin Beta 4 has tumor suppressive effects and its decreased expression results in poor prognosis and decreased survival in multiple myeloma
Caers, Jo ULg; Hose, Dirk; Kuijpers, Ine et al

in Haematologica (2010), 95(1), 163-167

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See detailDecreased Thymosin Beta 4 Expression Results in Poor Prognosis and Decreased Survival in Multiple Myeloma
CAERS, Jo ULg; Hose, Dirk; Kuipers, Ine et al

Poster (2008)

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See detailUnraveling the biology of MM disease: cancer stem cells, acquired intracellular changes and interactions with the surrounding micro-environment.
Caers, Jo ULg; Van Valckenborgh, Els; Menu, Eline et al

in Bulletin du Cancer (2008), 95(3), 301-13

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See detailAntitumor and anti-angiogenic effects of aplidin in the 5T33MM model, syngeneic model of multiple myeloma
Caers, Jo ULg; De Raeve, Hendrik; Lepage, Doreen et al

in British Journal of Cancer (2008), 98(12), 1966-74

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See detailDe bijdrage van muismodellen bij studies naar multipel myeloom
Vanderkerken, Karin; Van Valckenborgh, Els; Menu, Eline et al

in Nederlands Tijdschrift voor Hematologie (2007), 4(4), 193-143

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See detailThe involvement of osteopontin and its receptors in multiple myeloma cell survival, migration and invasion in the murine 5T33MM model
Caers, Jo ULg; Günthert, Ursula; De Raeve, Hendrik et al

in British Journal of Haematology (2006), 132((4)), 469-77

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