References of "Maudoux, Audrey"
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See detailIs oral feeding compatible with an unresponsive wakefulness syndrome?
MELOTTE, Evelyne ULiege; MAUDOUX, Audrey ULiege; DELHALLE, Sabrina ULiege et al

Conference (2017, May)

INTRODUCTION AND AIMS Vegetative state/Unresponsive wakefulness syndrome (VS/UWS) is defined by the presence of eye-opening and the absence of awareness and voluntary movement (Laureys et al., 2010). VS ... [more ▼]

INTRODUCTION AND AIMS Vegetative state/Unresponsive wakefulness syndrome (VS/UWS) is defined by the presence of eye-opening and the absence of awareness and voluntary movement (Laureys et al., 2010). VS/UWS patients classically receive hydration and nutrition through an enteral feeding tube. We present the cases of two patients that were diagnosed as VS/UWS but were able to resume oral feeding. It is however unclear if the presence of oral feeding is compatible with the diagnosis of VS/UWS or if this observation should lead to a modification of the diagnosis. METHODS AND RESULTS We retrospectively reviewed the clinical information of 65 VS/UWS patients (aged 45±12; range 16-85 years) evaluated at the CHU hospital of Liege searching for mention of oral feeding. VS/UWS diagnosis was made after repeated behavioral assessments using the standardized Coma Recovery Scale–Revised (CRS-R, (Teasdale & Jennet, 1974)) in association with complementary evaluations using neuroimaging techniques. Of the 65 VS/UWS patients, two could resume oral feeding (3%). One could achieve full oral feeding (mixed texture and liquid) and the other had oral feeding (liquid and semi-liquid) in addition to gastrostomy feeding. Neuroimaging evaluations showed in both patients a massive decrease in the spontaneous brain activity and its functional connectivity (using functional magnetic resonance imaging), bilateral cerebral cortex hypometabolism (fronto- parietal associative areas, posterior parietal areas, cingulate cortices, precuneus) and preserved metabolism in the brainstem and cerebellum (using positron emission tomography). CONCLUSIONS Oral feeding is rare in VS/UWS patients (3% in our cohort). Based on neuroimaging results, this behaviour does not seem to be incompatible with the diagnosis of VS/UWS but the neuromecanistic root, which allows this behavior, still needs to be elucidate. This study also emphasizes the importance of systematic swallowing evaluation in patients with altered state of consciousness regardless of their level of consciousness. Moreover, tactile oro-facial stimulation, manual therapy, taste stimulation and therapeutic feeding can be another “gateway” to interact with these patients and improve their quality of life. [less ▲]

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See detailFeasibility of Oral Feeding in Patients with Disorders of Consciousness
MAUDOUX, Audrey ULiege; Breuskin, I; Gosseries, Olivia ULiege et al

in Schnakers, C; LAUREYS, Steven (Eds.) Coma and Disorders of Consciousness, Second Edition (2017)

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See detailThe functional neuroanatomy of tinnitus: insights from resting-state fMRI
Maudoux, Audrey ULiege

Doctoral thesis (2012)

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See detailThe neuroscience of tinnitus: Perspectives from human neuroimaging studies
Maudoux, Audrey ULiege; Vanneste, Sven; De Ridder, Dirk et al

Conference (2012, November)

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See detailInvestigating the tinnitus brain using resting-state fMRI
Maudoux, Audrey ULiege; Vanneste, Sven; De Ridder, Dirk et al

Conference (2012, June)

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See detailAuditory Resting-State Network Connectivity in Tinnitus: a Functionnal MRI Study.
MAUDOUX, Audrey ULiege; LEFEBVRE, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

in PLoS ONE (2012)

The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test ... [more ▼]

The underlying functional neuroanatomy of tinnitus remains poorly understood. Few studies have focused on functional cerebral connectivity changes in tinnitus patients. The aim of this study was to test if functional MRI ‘‘resting-state’’ connectivity patterns in auditory network differ between tinnitus patients and normal controls. Thirteen chronic tinnitus subjects and fifteen age-matched healthy controls were studied on a 3 tesla MRI. Connectivity was investigated using independent component analysis and an automated component selection approach taking into account the spatial and temporal properties of each component. Connectivity in extra-auditory regions such as brainstem, basal ganglia/NAc, cerebellum, parahippocampal, right prefrontal, parietal, and sensorimotor areas was found to be increased in tinnitus subjects. The right primary auditory cortex, left prefrontal, left fusiform gyrus, and bilateral occipital regions showed a decreased connectivity in tinnitus. These results show that there is a modification of cortical and subcortical functional connectivity in tinnitus encompassing attentional, mnemonic, and emotional networks. Our data corroborate the hypothesized implication of non-auditory regions in tinnitus physiopathology and suggest that various regions of the brain seem involved in the persistent awareness of the phenomenon as well as in the development of the associated distress. leading to disabling chronic tinnitus. [less ▲]

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See detailConnectivity graph analysis of the auditory resting state network in tinnitus.
MAUDOUX, Audrey ULiege; Lefèbvre, Philippe ULiege; Cabay, J.-E. et al

in Brain Research (2012), 1485

Thirteen chronic tinnitus patients and fifteen age-matched healthy controls were studied on a 3T magnetic resonance imaging (MRI) scanner during resting condition (i.e. eyes closed, no task performance ... [more ▼]

Thirteen chronic tinnitus patients and fifteen age-matched healthy controls were studied on a 3T magnetic resonance imaging (MRI) scanner during resting condition (i.e. eyes closed, no task performance). The auditory resting-state component was selected using an automatic component selection approach. Functional connectivity (correlations/anti-correlations) in the extracted network was portrayed by integrating the independent component analysis (ICA) approach with a graph theory method. Tinnitus and control groups showed different graph connectivity patterns. In the control group, the connectivity graph was divided into two distinct anti-correlated networks. The first one encompassed the auditory cortices and the insula. The second one encompassed frontoparietal and anterior cingulate cortices, brainstem, amygdala, basal ganglia/nucleus accumbens and parahippocampal regions. In the tinnitus group, only one of the two previously described networks was observed, encompassing the auditory cortices and the insula. Direct group comparison showed, in the tinnitus group, an increased functional connectivity between auditory cortices and the left parahippocampal region surviving multiple comparisons. We investigated a possible correlation between four tinnitus relevant measures (tinnitus handicap inventory (THI) and tinnitus questionnaire (TQ) scores, tinnitus duration and tinnitus intensity during the scanning session) and the connectivity pattern in the tinnitus population. We observed a significant positive correlation between the beta values of the posterior cingulate/precuneus region and the THI score. Our results show a modified functional connectivity pattern in tinnitus sufferers and highlight the role of the parahippocampal region in tinnitus physiopathology. They also point out the importance of the activity and connectivity pattern of the posterior cingulate cortex/precuneus region to the development of the tinnitus associated distress. This article is part of a Special Issue entitled: Tinnitus Neuroscience. [less ▲]

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See detailFeasibility of oral feeding in patients with disorders of consciousness
Maudoux, Audrey ULiege; BREUSKIN, Ingrid ULiege; Gosseries, Olivia ULiege et al

in Schnakers, Caroline; Laureys, Steven (Eds.) Coma and Disorders of Consciousness (2012)

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See detailResting-state fMRI activity in tinnitus
MAUDOUX, Audrey ULiege

Conference (2011, August)

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See detailResting-state activity in the tinnitus brain
Maudoux, Audrey ULiege; LEFEBVRE, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

Conference (2011, March)

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See detailDisorders of consciousness: coma, vegetative and minimally conscious states
Gosseries, Olivia ULiege; Vanhaudenhuyse, Audrey ULiege; Bruno, Marie-Aurélie ULiege et al

in D. Cvetkovic & I. Cosic (Ed.) States of Consciousness: Experimental Insights into Meditation, Waking, Sleep and Dreams (2011)

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See detailResting-state fMRI activity in tinnitus
Maudoux, Audrey ULiege

Poster (2011)

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See detailFaisabilité d’une alimentation orale chez les patients avec troubles de la conscience
Maudoux, Audrey ULiege; BREUSKIN, Ingrid ULiege; Gosseries, Olivia ULiege et al

in Schnakers, Caroline (Ed.) Coma et états de conscience altérée (2011)

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See detailResting-state auditory network in tinnitus: a fMRI study
Maudoux, Audrey ULiege; LEFEBVRE, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

Poster (2010, June)

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See detailResting-state auditory network in tinnitus: a fMRI study
Maudoux, Audrey ULiege; LEFEBVRE, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

Conference (2010, June)

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See detailAcouphènes
Maudoux, Audrey ULiege

Conference (2010, March)

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See detailResting-state auditory network in tinnitus: a fMRI study
Maudoux, Audrey ULiege; LEFEBVRE, Philippe ULiege; CABAY, Jean-Evrard ULiege et al

Conference (2010, March)

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See detailImagerie fonctionnelle et audition.
MAUDOUX, Audrey ULiege; Poirrier, Anne-Lise ULiege; Lefèbvre, Philippe ULiege et al

in Cahiers de l'Audition (Les) (2010)

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See detailFunctional Neuroimaging Approaches to the Changing Borders of Consciousness
Noirhomme, Quentin ULiege; Soddu, Andrea ULiege; Vanhaudenhuyse, Audrey ULiege et al

in Journal of Psychophysiology (2010), 24(2), 68-75

The bedside diagnosis of vegetative and minimally conscious patients is extremely challenging, and prediction of individual long-term outcome remains difficult. State-of the art neuroimaging methods could ... [more ▼]

The bedside diagnosis of vegetative and minimally conscious patients is extremely challenging, and prediction of individual long-term outcome remains difficult. State-of the art neuroimaging methods could help disentangle complex cases and offer new prognostic criteria. These methods can be divided into to three categories: First, new anatomical MRI neuroimaging methods, like diffusion tensor imaging (DTI) or spectroscopy, and passive functional imaging methods (looking at the brain’s activation induced by external stimuli), could provide new diagnostic and prognostic markers. Second, neuroimaging methods based on active collaboration from the patient could help to detect clinically unnoticed signs of consciousness. Third, developments in brain-computer interfaces based on EEG, functional MRI, or EMG offer communication possibilities in brain-damaged patients who can neither verbally nor nonverbally express their thoughts or wishes. These new approaches raise important issues not only from a clinical and ethical perspective (i.e., patients’ diagnosis, prognosis and management) but also from a neuroscientific standpoint, as they enrich our current understanding of the emergence and function of the conscious human mind. [less ▲]

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