References of "Matarazzo, Luca"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailMemory Reactivation During Rapid Eye Movement (REM) Sleep Promotes Its Generalization and Integration in Cortical Stores
Sterpenich, Virginie; Schmidt, Christina ULg; Albouy, Genevièvre et al

in Sleep (2014), 37(6), 1061-1075

Memory reactivation appears to be a fundamental process in memory consolidation. Here, we tested the influence of memory reactivation during REM sleep on memory performance and brain responses at ... [more ▼]

Memory reactivation appears to be a fundamental process in memory consolidation. Here, we tested the influence of memory reactivation during REM sleep on memory performance and brain responses at retrieval in healthy human participants. Auditory cues were associated with pictures of faces during their encoding. These memory cues delivered during REM sleep enhanced subsequent accurate recollections but also false recognitions. These results suggest that reactivated memories interacted with semantically-related representations, and induced new creative associations, which subsequently reduced the distinction between new and previously encoded exemplars. Cues had no effect if presented during stage 2 sleep, or if they were not associated with faces during encoding. Functional MRI revealed that following exposure to conditioned cues during REM sleep, responses to faces during retrieval were enhanced both in a visual area and in a cortical region of multisensory (auditory-visual) convergence. These results show that reactivating memories during REM sleep enhances cortical responses during retrieval, suggesting the integration of recent memories within cortical circuits, favoring the generalization and schematization of the information. [less ▲]

Detailed reference viewed: 43 (2 ULg)
Full Text
Peer Reviewed
See detailThe impact of visual perceptual learning on sleep and local slow wave initiation
Mascetti, Laura ULg; Muto, Vincenzo ULg; Matarazzo, Luca et al

in Journal of Neuroscience (2013)

Detailed reference viewed: 59 (26 ULg)
Full Text
Peer Reviewed
See detailInfluence of acute sleep loss on the neural correlates of alerting, orientating and executive attention components
Muto, Vincenzo ULg; Shaffii, Anahita ULg; Matarazzo, Luca et al

in Journal of Sleep Research (2012), 21(6), 648-58

Detailed reference viewed: 51 (33 ULg)
See detailSleep, memory and the hippocampus
Foret, Ariane; Mascetti, Laura ULg; Kussé, Caroline ULg et al

in Clinical Neurobiology of the Hippocampus (2012)

Detailed reference viewed: 24 (9 ULg)
Peer Reviewed
See detailExperience-dependent induction of hypnagogic images during daytime naps: a combined behavioral and EEG study.
Kussé, Caroline ULg; Shaffii-Le Bourdiec, Anahita; Schrouff, Jessica ULg et al

in Association for the Scientific Study of Consciousness 15, Kyoto, Japan, 9-12 June 2011 (2011, June 09)

Detailed reference viewed: 8 (1 ULg)
Peer Reviewed
See detailAn easy-to-use pipeline for creating connectomes
Ziegler, Erik ULg; Foret, Ariane; Matarazzo, Luca et al

Poster (2011, June)

Detailed reference viewed: 15 (2 ULg)
Full Text
Peer Reviewed
See detailReciprocal interactions between wakefulness and sleep influence global and regional brain activity
Muto, Vincenzo ULg; Mascetti, Laura ULg; Matarazzo, Luca et al

in Current Topics in Medicinal Chemistry (2011), 11(19), 2403-13

Detailed reference viewed: 21 (11 ULg)
Peer Reviewed
See detailA systems-level approach to human REM sleep
Matarazzo, Luca; Foret, Ariane; Mascetti, Laura ULg et al

in Rapid Eye Movement Sleep: Regulation and Function (2011)

Detailed reference viewed: 14 (5 ULg)
Full Text
Peer Reviewed
See detailNeural Correlates of Human NREM Sleep Oscillations
Foret, Ariane ULg; Shaffii, Anahita ULg; Muto, Vincenzo ULg et al

in Hutt, Axel (Ed.) Sleep and Anesthesia (2011)

Detailed reference viewed: 26 (13 ULg)
Full Text
Peer Reviewed
See detailSpontaneous neural activity during human non-rapid eye movement sleep.
Mascetti, Laura ULg; Foret, Ariane ULg; Shaffii, Anahita ULg et al

in Progress in Brain Research (2011), 193

Recent neuroimaging studies characterized the neural correlates of slow waves and spindles during human non-rapid eye movement (NREM) sleep. They showed that significant activity was consistently ... [more ▼]

Recent neuroimaging studies characterized the neural correlates of slow waves and spindles during human non-rapid eye movement (NREM) sleep. They showed that significant activity was consistently associated with slow (> 140 muV) and delta waves (75-140 muV) during NREM sleep in several cortical areas including inferior frontal, medial prefrontal, precuneus, and posterior cingulate cortices. Unexpectedly, slow waves were also associated with transient responses in the pontine tegmentum and in the cerebellum. On the other hand, spindles were associated with a transient activity in the thalami, paralimbic areas (anterior cingulate and insular cortices), and superior temporal gyri. Moreover, slow spindles (11-13 Hz) were associated with increased activity in the superior frontal gyrus. In contrast, fast spindles (13-15 Hz) recruited a set of cortical regions involved in sensorimotor processing, as well as the mesial frontal cortex and hippocampus. These findings indicate that human NREM sleep is an active state during which brain activity is temporally organized by spontaneous oscillations (spindles and slow oscillation) in a regionally specific manner. The functional significance of these NREM sleep oscillations is currently interpreted in terms of synaptic homeostasis and memory consolidation. [less ▲]

Detailed reference viewed: 49 (24 ULg)
See detailInfluence of brain-derived neurotrophic factor val66met human polymorphism on declarative memory consolidation
Mascetti, Laura ULg; Foret, Ariane ULg; Matarazzo, Luca et al

Poster (2010, November 15)

The Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin which in the adult brain regulates long-term potentiation. In humans, valine (val) to methionine (met) substitution in the 5’ pro-region of ... [more ▼]

The Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin which in the adult brain regulates long-term potentiation. In humans, valine (val) to methionine (met) substitution in the 5’ pro-region of the BDNF protein is associated with poorer episodic memory. Neurons transfected with met-BDNF-Green Fluorescence Protein showed lower depolarization-induced secretion, while constitutive secretion is unchanged. Here, we hypothesized that the differences in BDNF release determined by this polymorphism would influence memory consolidation and that in comparison with the val/met (=val/met or met/met), val/val individuals would show higher memory performance and different brain responses during a 16h-delayed rather than immediate retrieval session. Participants encoded a series of neutral faces in the afternoon. Retrieval sessions took place one hour after the encoding session, and in the following morning, during the acquisition of functional Magnetic Resonance Imaging (fMRI) time series with a 3 Tesla Allegra scanner. During retrieval, studied faces and new ones were presented in random order. For each stimulus, the subjects indicated whether they could retrieve the encoding episode with (“Remember”), or without details (“Know”), or if they thought the item had not been presented during encoding (“New”). A repeated-measure ANOVA on discrimination index (d’) showed significant effects of group (F(1, 27)=8.65, p=0.007, n(val/val)=14, n(val/met)=15) and session (F(1, 27)=24.64, p=0.000), although the group by session interaction was not significant (F(1, 27)=1.29, p=0.267). fMRI results showed a significant genotype (val/val > val/met) by session (delayed > immediate retrieval) by memory type (Remember > Know) interaction in the right inferior occipital gyrus (x=42, y=-78, z=0, p=0.004, Z=3.77), the left inferior parietal lobule (x=-56, y=-40, z=48, p=0.013, Z=3.43), the posterior cingulate cortex (x=14, y=-42, z=42, p=0.019, Z=3.29) and the right hippocampus (x=28, y=-22, z=-22, p=0.03, Z=3.11). Val/val individuals demonstrate higher memory performance than met-carriers but the change in memory performance between immediate and delayed retests is similar in both allelic groups. In contrast, neural correlates of recollection change between sessions differently according to genotype: responses increase significantly more in val/val than in val/met individuals in brain areas involved in the retrieval, accumulation and binding of perceptual memory details during delayed, relative to immediate retest. These data suggest that activity-dependent BDNF release promotes memory consolidation during the first post-training hours. [less ▲]

Detailed reference viewed: 48 (10 ULg)
See detailInfluence of Brain-Derived Neurotrophic Factor val66met human polymorphism on declarative memory consolidation during sleep
Mascetti, Laura ULg; Foret, Ariane ULg; Matarazzo, Luca et al

Poster (2010, September 15)

Objectives The Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin which in the adult brain, regulates long-term potentiation and has been involved in the build up of the homeostatic sleep pressure ... [more ▼]

Objectives The Brain-Derived Neurotrophic Factor (BDNF) is a neurotrophin which in the adult brain, regulates long-term potentiation and has been involved in the build up of the homeostatic sleep pressure in rodents. In humans, valine (val) to methionine (met) substitution in the 5’ pro-region of the BDNF protein is associated with poorer episodic memory. Neurons transfected with met-BDNF-Green Fluorescence Protein showed lower depolarization-induced secretion, while constitutive secretion is unchanged. Here, we hypothesized that the differences in BDNF release determined by this polymorphism would influence sleep-dependent memory consolidation and that in comparison with the met-carriers (val/met or met/met), val/val individuals would show higher memory performance after one night of sleep rather than an immediate retrieval session. Methods Participants encoded a series of neutral faces in the afternoon. Retrieval sessions took place one hour after the encoding session, and in the following morning, after a night of polysomnographic-monitored sleep. During retrieval, studied faces and new ones were presented in random order. For each stimulus, the subjects indicated whether they could retrieve the encoding episode with (“Remember” response), or without details (“know” response), or if they thought the item had not been presented during encoding (“New” response). Results A repeated-measure ANOVA on discrimination index (d’) showed significant effects of group (F(1, 22)=4.66, p=0.042) and session (F(1, 22)=12.21, df=1, p=0.002). Although the group by session interaction was not significant (F(1, 22)=1.84, p=0.188), exploratory planned comparisons showed that at immediate retrieval, d’ was not significantly different between groups (val/val, d’ = 1.94±0.16; met-carriers, d’= 1.61±0.14; p>0.5). In contrast, during the second retest (the next day) d’ in the val/val group (d’=2.56±0.23) was significantly higher than in the met-carriers group (d’=1.88±0.21; p=0.041). Likewise, a between-session enhancement in d’ was detected only in the val/val population (p=0.003). Conclusion Val/val individuals demonstrate higher memory performance than met-carriers after a night of sleep but not at immediate retest. These data suggest that activity-dependent BDNF release promotes memory consolidation during the first post-training hours. Further analysis of the present data set will assess the respective effect of sleep and time on the BDNF-associated delayed memory enhancement. This study was supported by FNRS-FRIA, the University of Liège, and the QEMF. [less ▲]

Detailed reference viewed: 30 (5 ULg)
Full Text
Peer Reviewed
See detailContribution of sleep to memory consolidation
Shaffii-Le Bourdiec, Anahita; Muto, Vincenzo ULg; Mascetti, Laura et al

in Future Neurology (2010), 5(2), 325-338

Detailed reference viewed: 18 (1 ULg)
Full Text
Peer Reviewed
See detailNeuroimaging of dreaming: state of the art and limitations
Kussé, Caroline ULg; Muto, Vincenzo ULg; Mascetti, Laura ULg et al

in International Review of Neurobiology (2010)

Detailed reference viewed: 51 (22 ULg)
See detailNeuroimaging Insights into the Dreaming Brain
Desseilles, Martin ULg; Dang Vu, Thien Thanh ULg; Schabus, Manuel et al

in Dreams and Dreaming (2010)

Detailed reference viewed: 14 (2 ULg)
Full Text
Peer Reviewed
See detailSome facts about sleep relevant for Landau-Kleffner syndrome.
Mascetti, Laura ULg; Foret, Ariane ULg; Bonjean, Maxime et al

in Epilepsia (2009), 50 Suppl 7

Our understanding of the neural mechanisms of non-rapid eye movement sleep (NREM) is steadily increasing. Given the intriguing activation of paroxysmal activity during NREM sleep in patients with Landau ... [more ▼]

Our understanding of the neural mechanisms of non-rapid eye movement sleep (NREM) is steadily increasing. Given the intriguing activation of paroxysmal activity during NREM sleep in patients with Landau-Kleffner syndrome (LKS), a thorough characterization of commonalities and differences between the neural correlates of LKS paroxysms and normal sleep oscillations might provide useful information on the neural underpinning of this disorder. Especially, given the suspected role of sleep in brain plasticity, this type of information is needed to assess the link between cognitive deterioration and electroencephalography (EEG) paroxysms during sleep. [less ▲]

Detailed reference viewed: 22 (3 ULg)