Long-Term Protection Against Bovine Leukaemia Virus Replication In Cattle And Sheep

in Journal of General Virology (2000), 81

The Creb, Atf-1, And Atf-2 Transcription Factors From Bovine Leukemia Virus-Infected B Lymphocytes Activate Viral Expression

in Journal of Virology (1996), 70(3),

The Yxxl Signaling Motifs Of The Bovine Leukemia-Virus Transmembrane Protein Are Required For In-Vivo Infection And Maintenance Of High Viral Loads

in Journal of Virology (1995), 69(7),

Involvement Of The Cyclic Amp-Responsive Element-Binding Protein In Bovine Leukemia-Virus Expression In-Vivo

in Journal of Virology (1994), 68(9),

Epidemiological evaluation of a monoclonal ELISA detecting antibodies against bovine leukaemia virus in serum pools.

in Epidemiology & Infection (1994), 113(3), 563-9

Sensitivity, specificity and predictive values of an enzyme-linked immunosorbent assay (ELISA) for detecting antibodies against bovine leukaemia virus (BLV) were evaluated using a representative sample of ... [more ▼]

Sensitivity, specificity and predictive values of an enzyme-linked immunosorbent assay (ELISA) for detecting antibodies against bovine leukaemia virus (BLV) were evaluated using a representative sample of 145 serum pools, comprising from 3 to 48 individual sera. The sample was constituted according to the frequency distribution of the negative and positive pools analysed during a screening involving the whole cattle population of Belgium. Sensitivity and specificity were estimated to 88.9% and 100% and the predicted negative and positive values were 99.9% and 100%, respectively. These results indicate the use of serum pools is suitable for the detection of BLV infected herds in eradication campaigns. [less ▲]

In vivo infection of sheep by bovine leukemia virus mutants.

in Journal of virology (1993), 67(7),

Mapping Of B-Neutralizing And T-Helper Cell Epitopes On The Bovine Leukemia-Virus External Glycoprotein Gp51

in Journal of Virology (1993), 67(9),

Eradication de la leucose bovine enzootique en Belgique : estimation du temps nécessaire à l'assainissement des foyers découverts

in Annales de Médecine Vétérinaire (1991), 135(4), 281-285

Bovine leukemia : facts and hypotheses derived from the study of an infectious cancer

in Retroviruses biology and human disease, Dekker Press (1990)

Antigenic Variants Of Bovine Leukemia-Virus (Blv) Are Defined By Amino-Acid Substitutions In The Nh2 Part Of The Envelope Glycoprotein-Gp51

in Virology (1989), 169(1),

Bovine leukemia virus (BLV) p24 gene was expressed in Saccharomyces cerevisiae under the control of the PHO5 (encoding repressible acid phosphatase, rAPase) promoter. Yeast cells were transformed by a ... [more ▼]

Bovine leukemia virus (BLV) p24 gene was expressed in Saccharomyces cerevisiae under the control of the PHO5 (encoding repressible acid phosphatase, rAPase) promoter. Yeast cells were transformed by a yeast-E. coli shuttle vector carrying the PHO5 promoter, the p24 gene and the CYC1 transcription terminator. After low inorganic phosphate (Pi) induction of the PHO5 promoter, p24 accumulated in the producing cells up to a concentration representing 10% of total soluble proteins. The expression level of p24 gene was not increased by insertion of the positive regulatory gene PHO4 on the p24 expression vector. The p24 produced in this system and incubated in crude yeast extract showed a remarkably high resistance to proteolytic degradation, a feature that presumably correlates with the compact globular conformation of the protein combined to the stabilizing effect of the N-terminal residue. [less ▲]