Determination of seven azole antifungals in human serum by UHPLC-DAD.

Poster (2012, October 20)

Determination of seven azole antifungal drugs in human serum by UHPLC-DAD and its clinical application

Poster (2012)

Intérêt des anticorps monoclonaux dans le laboratoire d'analyses biomédicales

in Revue Médicale de Liège (2009), 64(5-6), 257-263

Circulating Concentrations of 25-Hydroxyvitamin D after a Single Oral Dose of 100.000 IU of Vitamin D2 or Vitamin D3

in Journal of Bone and Mineral Research (2008, September), 23

Vitamine D2 ou vitamine D3?

in Revue de Médecine Interne (2008), 29(10), 815-20

PURPOSE: Nearly one billion people around the world are deficient in vitamin D and need to be supplemented. Vitamin D is available in medicines and fortified foods. It is available in two forms: vitamin ... [more ▼]

PURPOSE: Nearly one billion people around the world are deficient in vitamin D and need to be supplemented. Vitamin D is available in medicines and fortified foods. It is available in two forms: vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). KEY POINTS: The pharmacopeiae consider these steroid hormones as equivalent and interchangeable. However, several studies have showed that serum level of 25(OH)D is increased more effectively with vitamin D3 than vitamin D2. Vitamin D2 has shorter plasma half-life and a lower affinity for the vitamin D binding protein, the hepatic vitamin D hydroxylase and the vitamin D receptor. CONCLUSION: Vitamin D2 should not be regarded anymore as suitable for supplementation or fortification. Currently though, it is still the most used in some countries such as Portugal and Australia. [less ▲]